Andrew P Mazar

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study
    Martin C Boonstra
    Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands
    BMC Cancer 14:269. 2014
  2. pmc Development of novel therapeutics targeting the urokinase plasminogen activator receptor (uPAR) and their translation toward the clinic
    Andrew P Mazar
    Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA
    Curr Pharm Des 17:1970-8. 2011
  3. pmc The many spaces of uPAR: delivery of theranostic agents and nanobins to multiple tumor compartments through a single target
    THOMAS V O'HALLORAN
    Robert H Lurie Comprehensive Cancer Center, Northwestern University 2145 Sheridan Rd, Evanston, IL 60208, USA
    Theranostics 3:496-506. 2013
  4. pmc Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo
    Richard W Ahn
    Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America
    PLoS ONE 8:e58491. 2013
  5. pmc Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV
    Ji Young Yoo
    Dardinger Laboratory for Neuro oncology and Neurosciences, Northwestern University, Evanston, Illinois, USA
    Clin Cancer Res 18:4931-41. 2012

Collaborators

  • THOMAS V O'HALLORAN
  • Jane N Winter
  • E Antonio Chiocca
  • Martin C Boonstra
  • Richard W Ahn
  • Ji Young Yoo
  • Cornelis F M Sier
  • Cornelis J H Van De Velde
  • Peter J K Kuppen
  • Hendrica A J M Prevoo
  • Alexander L Vahrmeijer
  • Floris P R Verbeek
  • Susan L Barrett
  • Haimei Chen
  • Meera R Raja
  • Lonnie D Shea
  • Leo I Gordon
  • Marcel B Bally
  • Jennifer K Jozefik
  • Michael J Avram
  • Lidia Spaho
  • Teresa K Woodruff
  • Joseph C Glorioso
  • Christopher A Alvarez-Breckenridge
  • Jun Ge Yu
  • Jason Pradarelli
  • Anna Bratasz
  • Azeem Kaka
  • Theodoros N Teknos
  • Balveen Kaur
  • Kimerly Powell
  • Jeffrey Wojton
  • Matthew Old
  • Amy Haseley

Detail Information

Publications5

  1. pmc Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study
    Martin C Boonstra
    Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands
    BMC Cancer 14:269. 2014
    ..This study compares the association of uPAR expression in both colorectal tumor-associated stromal cells and neoplastic cells with clinico-pathological characteristics and patient survival using tissue micro arrays (TMA)...
  2. pmc Development of novel therapeutics targeting the urokinase plasminogen activator receptor (uPAR) and their translation toward the clinic
    Andrew P Mazar
    Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA
    Curr Pharm Des 17:1970-8. 2011
    ..This review will discuss some of the pitfalls that have delayed progress on uPAR-targeted interventions and will summarize recent progress in the development of uPAR-targeted therapeutics...
  3. pmc The many spaces of uPAR: delivery of theranostic agents and nanobins to multiple tumor compartments through a single target
    THOMAS V O'HALLORAN
    Robert H Lurie Comprehensive Cancer Center, Northwestern University 2145 Sheridan Rd, Evanston, IL 60208, USA
    Theranostics 3:496-506. 2013
    ..This review will highlight some of these new discoveries and the new uPA system-based therapeutic approaches that have arisen from them. ..
  4. pmc Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo
    Richard W Ahn
    Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America
    PLoS ONE 8:e58491. 2013
    ....
  5. pmc Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV
    Ji Young Yoo
    Dardinger Laboratory for Neuro oncology and Neurosciences, Northwestern University, Evanston, Illinois, USA
    Clin Cancer Res 18:4931-41. 2012
    ..Here, we tested whether copper inhibits oHSV infection and replication and whether copper chelation would augment therapeutic efficacy of oHSV...