J Levitsky

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint Operational tolerance: past lessons and future prospects
    Josh Levitsky
    Division of Hepatology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 17:222-32. 2011
  2. doi request reprint Outcomes and native renal recovery following simultaneous liver-kidney transplantation
    J Levitsky
    Comprehensive Transplant Center, Northwestern University, Chicago, IL, USA
    Am J Transplant 12:2949-57. 2012
  3. pmc Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients
    Josh Levitsky
    Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Hepatology 57:239-48. 2013
  4. doi request reprint Meeting report of the International Liver Transplantation Society's 18th annual international congress: Hilton San Francisco Hotel, San Francisco, CA, May 16-19, 2012
    Josh Levitsky
    Division of Gastroenterology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 19:27-35. 2013
  5. doi request reprint Risk for immune-mediated graft dysfunction in liver transplant recipients with recurrent HCV infection treated with pegylated interferon
    Josh Levitsky
    Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
    Gastroenterology 142:1132-1139.e1. 2012
  6. doi request reprint Meeting report of the 2011 Joint International Congress of the International Liver Transplantation Society, the European Liver and Intestine Transplant Association, and the Liver Intensive Care Group of Europe
    Josh Levitsky
    Division of Gastroenterology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Chicago, IL 60611, USA
    Liver Transpl 18:282-9. 2012
  7. doi request reprint Alemtuzumab induction in non-hepatitis C positive liver transplant recipients
    Josh Levitsky
    Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 17:32-7. 2011
  8. ncbi request reprint A survey of CMV prevention strategies after liver transplantation
    J Levitsky
    Department of Medicine, Division of Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Transplant 8:158-61. 2008
  9. ncbi request reprint Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction
    Josh Levitsky
    Division of Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Transplantation 91:199-206. 2011
  10. ncbi request reprint Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents
    Josh Levitsky
    Division of Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Hum Immunol 70:146-50. 2009

Collaborators

Detail Information

Publications35

  1. doi request reprint Operational tolerance: past lessons and future prospects
    Josh Levitsky
    Division of Hepatology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 17:222-32. 2011
    ....
  2. doi request reprint Outcomes and native renal recovery following simultaneous liver-kidney transplantation
    J Levitsky
    Comprehensive Transplant Center, Northwestern University, Chicago, IL, USA
    Am J Transplant 12:2949-57. 2012
    ..85, CI 1.22-12.5). Our data support the need to refine SLK selection utilizing more definitive biomarkers and predictors of native renal recovery than current clinical criteria...
  3. pmc Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients
    Josh Levitsky
    Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Hepatology 57:239-48. 2013
    ..Finally, 289 novel genes and 22 proteins, several important in immunoregulatory pathways, were expressed after conversion...
  4. doi request reprint Meeting report of the International Liver Transplantation Society's 18th annual international congress: Hilton San Francisco Hotel, San Francisco, CA, May 16-19, 2012
    Josh Levitsky
    Division of Gastroenterology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 19:27-35. 2013
    ..As always, the new data herein are presented in the context of the published literature to further enhance knowledge in the field...
  5. doi request reprint Risk for immune-mediated graft dysfunction in liver transplant recipients with recurrent HCV infection treated with pegylated interferon
    Josh Levitsky
    Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
    Gastroenterology 142:1132-1139.e1. 2012
    ..Patients with recurrent hepatitis C virus infection treated with pegylated interferon (PEG) after liver transplantation can develop severe immune-mediated graft dysfunction (IGD) characterized by plasma cell hepatitis or rejection...
  6. doi request reprint Meeting report of the 2011 Joint International Congress of the International Liver Transplantation Society, the European Liver and Intestine Transplant Association, and the Liver Intensive Care Group of Europe
    Josh Levitsky
    Division of Gastroenterology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Chicago, IL 60611, USA
    Liver Transpl 18:282-9. 2012
    ..It is not meant to be a critical or comprehensive evaluation of all the meeting presentations and is merely intended to highlight presentations and associated published literature dealing with key topics...
  7. doi request reprint Alemtuzumab induction in non-hepatitis C positive liver transplant recipients
    Josh Levitsky
    Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 17:32-7. 2011
    ..In conclusion, a steroid-free AL induction regimen was associated with less hypertension and rejection but with more infectious complications; thus, the overall benefit of AL induction in LT recipients is called into question...
  8. ncbi request reprint A survey of CMV prevention strategies after liver transplantation
    J Levitsky
    Department of Medicine, Division of Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Transplant 8:158-61. 2008
    ..In conclusion, the majority of LT centers utilize CMV prophylaxis over other strategies. Valganciclovir is the most commonly used agent for both antiviral prophylaxis and treatment of CMV viremia in the preemptive approach...
  9. ncbi request reprint Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction
    Josh Levitsky
    Division of Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Transplantation 91:199-206. 2011
    ....
  10. ncbi request reprint Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents
    Josh Levitsky
    Division of Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Hum Immunol 70:146-50. 2009
    ..However, TAC patients may have other regulatory characteristics, supporting the need for larger, prospective studies to clarify differences...
  11. pmc Detection and diagnosis of herpes simplex virus infection in adults with acute liver failure
    Josh Levitsky
    Northwestern Memorial Hospital Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Liver Transpl 14:1498-504. 2008
    ....
  12. ncbi request reprint Hepatic complications of hematopoietic cell transplantation
    Josh Levitsky
    Department of Medicine, Division of Hepatology, Northwestern University Feinberg School of Medicine, 675 N St Clair, 15 250, Chicago, IL 60611, USA
    Curr Gastroenterol Rep 9:60-5. 2007
    ..Because treatments are directed at the underlying etiology of liver disease, prompt diagnosis by means of laboratory tests, hepatic imaging, and often liver biopsy is required after HCT...
  13. ncbi request reprint The liver transplant recipient: what you need to know for long-term care
    Josh Levitsky
    Hepatology Division, Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, 675 North St Clair Street, Chicago, IL 60611, USA
    J Fam Pract 55:136-44. 2006
    ..Patients should wait at least 2 years before considering pregnancy and use barrier-type methods in this period. Vaccinate patients against hepatitis A and B, influenza, and pneumococcus. Avoid live vaccines...
  14. doi request reprint Next level of immunosuppression: drug/immune monitoring
    Josh Levitsky
    Division of Hepatology and Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 17:S60-5. 2011
    ..6. Future immune monitoring assays should be focused on genomic or immunological predispositions and on specific reactivities to donor antigens to guide the appropriate dosing and minimization of IS after LT...
  15. pmc Clinical and plasma proteomic markers correlating with chronic kidney disease after liver transplantation
    J Levitsky
    Comprehensive Transplant Center Division of Hepatology, Northwestern University, Chicago, IL, USA
    Am J Transplant 11:1972-8. 2011
    ..These preliminary results are currently being validated in a prospective, multicenter study to determine if this signature precedes the onset of CKD and resolves with early interventions aimed at preserving kidney function...
  16. doi request reprint A non-induction renal sparing approach after liver transplantation: high dose mycophenolate mofetil with delayed, low-dose tacrolimus
    V Rao
    Department of Internal Medicine, Loyola University Medical Center, Chicago, Illinois, USA
    Transplant Proc 45:320-2. 2013
    ....
  17. doi request reprint Factors associated with sustained virological response in liver transplant recipients with recurrent hepatitis C
    A A Pillai
    Department of Transplant Surgery and Hepatology, Northwestern Memorial Hospital, and Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Transplant Proc 42:3647-51. 2010
    ..Antiviral therapy has achieved sustained virological response (SVR) in less than one third of orthotopic liver transplantation (OLT) patients with recurrent hepatitis C...
  18. ncbi request reprint Acid-base and potassium disorders in liver disease
    Shubhada N Ahya
    Division of Nephrology and Hypertension, Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Semin Nephrol 26:466-70. 2006
    ..Potassium disorders are often the result of the therapies used to treat advanced liver disease...
  19. pmc Posttransplant hyperglycemia is associated with increased risk of liver allograft rejection
    Amisha Wallia
    Division of Endocrinology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Transplantation 89:222-6. 2010
    ..Intensive glycemic control has been shown to positively impact outcomes in an intensive care setting. Whether this practice is beneficial after liver transplantation (LT) is not known...
  20. doi request reprint Role of pretransplant echocardiographic evaluation in predicting outcomes following liver transplantation
    L Kia
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
    Am J Transplant 13:2395-401. 2013
    ..In conclusion, pre-LT echocardiographic assessments of the right heart may be useful in predicting post-LT morbidity and mortality and guiding the selection of appropriate LT candidates...
  21. doi request reprint Evaluation of the coagulation and inflammatory responses in solid organ transplant recipients and donors
    Josh Levitsky
    Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Clin Transplant 23:943-50. 2009
    ..This activation diminishes over time unless transplant complications occur. Our results support further research in approaches to altering these cascades in SOT recipients...
  22. ncbi request reprint American Association for the Study of Liver Diseases--53rd Annual Meeting. 1-5 November 2002, Boston, MA, USA
    Josh Levitsky
    Gastroenterology Division, University of Chicago Hospitals, 5842 South Maryland Avenue, Chicago, IL 60637, USA
    IDrugs 6:30-3. 2003
  23. doi request reprint Outcomes of patients with hepatitis C undergoing simultaneous liver-kidney transplantation
    Lisa B Van Wagner
    Division of Hepatology, Medicine Northwestern University, Chicago, IL, USA
    J Hepatol 51:874-80. 2009
    ..The number of simultaneous liver-kidney transplants (SLK) has increased since the MELD era. Data on short- and long-term outcomes of hepatitis C virus positive (HCV+) SLK compared to HCV+ liver transplant alone (LTA) recipients are limited...
  24. pmc The human "Treg MLR": immune monitoring for FOXP3+ T regulatory cell generation
    Josh Levitsky
    Division of Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Transplantation 88:1303-11. 2009
    ..Controversy exists about the conditions effecting the development of forkhead/winghead helix transcription factor P3 (FOXP3) expressing T cells and their relevance in transplant recipients...
  25. ncbi request reprint Herpes simplex virus hepatitis: an analysis of the published literature and institutional cases
    John P Norvell
    Department of Internal Medicine, Division of Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 13:1428-34. 2007
    ..Based on the frequent delay in HSV diagnosis, low risk-benefit ratio, and significantly improved outcomes, empiric acyclovir therapy for patients presenting with ALF of unknown etiology is recommended until HSV hepatitis is excluded...
  26. ncbi request reprint The safety and outcome of joint replacement surgery in liver transplant recipients
    Josh Levitsky
    Center for Liver Diseases, Gastroenterology Division, University of Chicago Hospitals, IL, USA
    Liver Transpl 9:373-6. 2003
    ..Our study suggests that joint replacement surgery may be safely and successfully performed in this population, although larger, randomized, prospective trials are needed to confirm our findings...
  27. ncbi request reprint Operative risk of total hip and knee arthroplasty in cirrhotic patients
    Stanley Martin Cohen
    University of Chicago, Division of Gastroenterology, Liver Study Unit, Chicago, IL, USA
    J Arthroplasty 20:460-6. 2005
    ..However, emergent THA to repair fractures in cirrhotic patients is associated with significantly increased morbidity and mortality...
  28. ncbi request reprint Chicken pox after pediatric liver transplantation
    Josh Levitsky
    Department of Medicine, Division of Hepatology, Northwestern Memorial Hospital, Feinberg School of Medicine, Chicago, IL, USA
    Liver Transpl 11:1563-6. 2005
    ..No risk factors were identified. Some cases required prolonged hospitalizations. Close monitoring for the development of late bacterial infections is warranted...
  29. doi request reprint Cytomegalovirus viremia in solid organ transplantation: does the initial viral load correlate with risk factors and outcomes?
    Josh Levitsky
    Division of Hepatology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Clin Transplant 22:222-8. 2008
    ..Alternatively, late asymptomatic viremia and recurrent CMV are associated with lower PCR levels and a low likelihood to progress and result in clinical disease...
  30. ncbi request reprint Meta-analysis: the efficacy of strategies to prevent organ disease by cytomegalovirus in solid organ transplant recipients
    Andre C Kalil
    University of Nebraska Medical Center, Omaha, Nebraska 68198 5400, USA
    Ann Intern Med 143:870-80. 2005
    ..Cytomegalovirus (CMV), the most common opportunistic viral infection in solid organ transplant recipients, is associated with substantial morbidity and mortality...
  31. ncbi request reprint Fulminant liver failure associated with the use of black cohosh
    Josh Levitsky
    Department of Gastroenterology, University of Nebraska Medical Center, Omaha, Nebraska 68198 3285, USA
    Dig Dis Sci 50:538-9. 2005
  32. ncbi request reprint Herpes zoster infection after liver transplantation: a case-control study
    Josh Levitsky
    Department of Internal Medicine Gastroenterology, University of Nebraska Medical Center, University of Nebraska, Omaha, Nebraska, 68198 5400, USA
    Liver Transpl 11:320-5. 2005
    ..In conclusion, this study is the largest series on HZ after OLT. HZ is neither a common nor a serious infection after OLT and can be managed with antiviral therapy with a low likelihood of visceral dissemination...
  33. ncbi request reprint The effect of immunosuppressive regimens on the recurrence of primary biliary cirrhosis after liver transplantation
    Josh Levitsky
    Center for Liver Diseases, The University of Chicago Hospitals, IL 60637, USA
    Liver Transpl 9:733-6. 2003
    ..In conclusion, recurrent PBC developed in a small number of patients 2 years or longer after OLT. In our population, there was no difference in recurrence rates between those administered cyclosporine or tacrolimus for immunosuppression...
  34. ncbi request reprint Varicella infection following varicella vaccination in a liver transplant recipient
    Josh Levitsky
    Center for Liver Diseases Section of Gastroenterology, University of Chicago Hospitals, IL, USA
    Am J Transplant 2:880-2. 2002
    ..We will discuss VZV infection, particularly in relation to liver transplantation, and review the prophylaxis and management of VZV infection after OLT...
  35. ncbi request reprint Group G streptococcal bacteremia and de novo hepatocellular carcinoma after liver transplantation
    Josh Levitsky
    Liver Transpl 8:572. 2002