C B Langman
Affiliation: Northwestern University
- A randomized controlled crossover trial with delayed-release cysteamine bitartrate in nephropathic cystinosis: effectiveness on white blood cell cystine levels and comparison of safetyCraig B Langman
Division of Kidney Diseases, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60614, USA
Clin J Am Soc Nephrol 7:1112-20. 2012..Cystagon efficacy requires strict lifelong dosing every 6 hours. Such a dosing schedule and Cystagon-associated side effects are often cited by patients as reasons for nonadherence...
- The optimal approach to the patient with oxalosisC B Langman
Department of Pediatrics, Northwestern University Medical School, Chicago, IL, USA
Adv Ren Replace Ther 8:214-22. 2001..It ends with potential, innovative therapies that are not yet at the patient's bedside...
- Renal osteodystrophy: a pediatric perspective, 2005Craig B Langman
Feinberg School of Medicine, Northwestern University, and Children s Memorial Hospital, 2300 Children s Plaza, MS 37, Chicago, IL 60614, USA
Growth Horm IGF Res 15:42-7. 2005..An algorithmic approach to the management of ROD in children is presented; to be most effective, this approach requires close and frequent surveillance to prevent side effects related to potent therapies...
- Genetic regulation of bone mass: from bone density to bone strengthCraig B Langman
Division of Kidney Diseases, Children s Memorial Hospital, 2300 Children s Plaza, MS 37, Chicago, IL 60614, USA
Pediatr Nephrol 20:352-5. 2005..Future therapeutics for improving peak bone density or delaying bone loss later in life may take advantage of the genetic nature of bone density development...
- Women with wrist fractures are at increased risk for future fractures because of both skeletal and non-skeletal risk factorsBeatrice J Edwards
Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Age Ageing 35:438-41. 2006
- Osteoporosis screening of postmenopausal women in the primary care setting: a case-based approachBeatrice J Edwards
Bone Health and Osteoporosis Program, Division of Geriatric Medicine, Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Gend Med 1:70-85. 2004....
- Short-term reduction in bone markers with high-dose simvastatinRobert S Rosenson
Preventive Cardiology Center, Division of Cardiology, Departments of Medicine and Preventive Medicine, Northwestern University, Feinberg School of Medicine, 301 E Huron Street, Galter Pavilion, Chicago, IL 60611, USA
Osteoporos Int 16:1272-6. 2005..Short-term use of high-dose simvastatin lowers the level of the serum bone marker bone-specific alkaline phosphatase, which suggests the possibility of reduced bone turnover...
- Assessing cardiovascular risk in children with chronic kidney disease. B-type natriuretic peptide: a potential new markerGema Ariceta
Division of Kidney Diseases, Children s Memorial Hospital, Chicago, IL 60614, USA
Pediatr Nephrol 20:1701-7. 2005..It is appropriate to analyze the potential application of this tool in children with CKD, a well-known factor for CV disease...
- The molecular basis of kidney stonesCraig B Langman
Feinberg School of Medicine, Northwestern University, Kidney Diseases, Children s Memorial Hospital, Chicago, Illinois 60614, USA
Curr Opin Pediatr 16:188-93. 2004..To emphasize an exploration of mechanisms of kidney stone disease based on a molecular understanding of excess urinary excretions of calcium, oxalate, cystine, and uric acid...
- Bioelectric impedance predicts total body water, blood pressure, and heart rate during hemodialysis in children and adolescentsEllen R Brooks
Department of Pediatrics, Division of Kidney Diseases, Northwestern University Feinberg Medical School, Children s Memorial Hospital, Chicago, Illinois 60614, USA
J Ren Nutr 18:304-11. 2008....
- Methylated arginine derivatives in children and adolescents with chronic kidney diseaseEllen R Brooks
Department of Pediatrics, Division of Kidney Diseases, Children s Memorial Hospital and Northwestern University Feinberg Medical School, Chicago, IL, USA
Pediatr Nephrol 24:129-34. 2009..SDMA is a strong marker for reduced eGFR and serves as a moderate but significant indicator of 24-hr BP load variability...
- Vitamin D deficiency in children with chronic kidney disease: uncovering an epidemicFarah N Ali
Feinberg School of Medicine, Northwestern University, Children s Memorial Hospital, 2300 Children s Plaza, Box 37, Chicago, IL 60614, USA
Pediatrics 123:791-6. 2009....
- Renal osteodystrophy in children: a systemic disease associated with cardiovascular manifestationsCraig B Langman
Children s Memorial Hospital, 2300 Children s Plaza, MS 37, Chicago, IL 60614, USA
Growth Horm IGF Res 16:S79-83. 2006..Preliminary studies indicate that vitamin D therapy for control of secondary hyperparathyroidism may confer cardioprotection and reduce mortality. Attention to care of osteodystrophy in CKD must take into account heart health as well...
- RANKL:osteoprotegerin ratio and bone mineral density in children with untreated juvenile dermatomyositisKelly A Rouster-Stevens
Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60614, USA
Arthritis Rheum 56:977-83. 2007....
- 25-hydroxyvitamin D and cardiovascular risk factors in women with systemic lupus erythematosusPeggy W Wu
Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Arthritis Rheum 61:1387-95. 2009..Vitamin D deficiency has also been noted in systemic lupus erythematosus (SLE). The objective of this study was to evaluate the associations of serum 25(OH)D levels with cardiovascular risk factors in women with SLE...
- Secondary contributors to bone loss in osteoporosis related hip fracturesB J Edwards
Bone Health and Osteoporosis Center, Department of Medicine, Feinberg School of Medicine, Northwestern University, 645 N Michigan, Suite 630, Chicago, IL 60611, USA
Osteoporos Int 19:991-9. 2008..Identifying and managing these disorders will improve detection and enhance treatment aimed at reducing the risk of recurrent fractures in older adults...
- New developments in calcium and vitamin D metabolismC B Langman
Department of Pediatrics, Northwestern University, Evanston, Illinois, USA
Curr Opin Pediatr 12:135-9. 2000....
- Vitamin D depletion following burn injury in children: a possible factor in post-burn osteopeniaGordon L Klein
Department of Pediatrics, University of Texas Medical Branch at Galveston and Shriners Burns Hospital, 77555 0352, USA
J Trauma 52:346-50. 2002..Because they are advised to avoid sunlight to prevent burn scar hyperpigmentation, we hypothesized that they develop vitamin D depletion, which could contribute to post-burn osteopenia...
- Effects of therapy with recombinant human growth hormone on insulin-like growth factor system components and serum levels of biochemical markers of bone formation in children after severe burn injuryG L Klein
Department of Pediatrics, University of Texas Medical Branch, Galveston 77555 0352, USA
J Clin Endocrinol Metab 83:21-4. 1998..The rHGH-independent rise in serum levels of the inhibitory binding protein IGFBP-4 suggests a mechanism by which improved bone formation is prevented despite successful elevation of IGF-1 and IGFBP-3 in the burned child...
- Sodium modeling attenuates rises in whole-blood viscosity during chronic hemodialysis in children with large inter-dialytic weight gainSahar A Fathallah-Shaykh
Division of Kidney Diseases, Department of Pediatrics, Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Pediatr Nephrol 21:1179-84. 2006..05). WBV increased during HD in children. NaM appears to attenuate the rise in WBV in children with large IDWG...
- Dose of dialysis based on body surface area is markedly less in younger children than in older adolescentsJohn T Daugirdas
University of Illinois at Chicago, 820 S Wood Street, N C 793, Chicago, IL 60612, USA
Clin J Am Soc Nephrol 5:821-7. 2010..Normalizing Kt/V to body surface area (S) has been proposed, but the implications of doing this in children have not been examined...
- Serum concentrations of lipids, vitamin d metabolites, retinol, retinyl esters, tocopherols and selected carotenoids in twelve captive wild felid species at four zoosSusan D Crissey
Daniel F. and Ada L. Rice Conservation Biology and Research Center, Chicago Zoological Society, Brookfield, IL, USA
J Nutr 133:160-6. 2003..The large number of animals analyzed provides a substantial base for comparing the serum nutrient concentrations of healthy animals, for both wild and captive exotic species...
- Report of an NIH task force on research priorities in chronic kidney disease in childrenRussell W Chesney
Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, 38103-4909, USA
Pediatr Nephrol 21:14-25. 2006
- Hyperoxaluria and systemic oxalosis: current therapy and future directionsAmy E Bobrowski
Feinberg School of Medicine, Northwestern University, Division of Kidney Diseases, Department of Pediatrics, Children s Memorial Hospital, 2300 Children s Plaza 37, Chicago, IL 60614, USA
Expert Opin Pharmacother 7:1887-96. 2006..Such approaches give hope for a future therapeutic cure for primary hyperoxaluria that includes correction of the underlying genetic defect without exposure to the life-long dangers associated with organ transplantation...
- Heritability and environmental factors affecting vitamin D status in rural Chinese adolescent twinsLester M Arguelles
M S, Mary Ann and J Milburn Smith Child Health Research Program, Children s Memorial Hospital and Children s Memorial Research Center, 2300 Children s Plaza, Box 157, Chicago, Illinois 60614 3394, USA
J Clin Endocrinol Metab 94:3273-81. 2009..Factors associated with the high prevalence of vitamin D deficiency in China are not well described, especially among Chinese adolescents...
- Hepatic osteodystrophy in chronic cholestasis: evidence for a multifactorial etiologyGordon L Klein
Pediatric Gastroenterology Division, Children s Hospital, University of Texas Medical Branch, Galveston TX 77555 0352, USA
Pediatr Transplant 6:136-40. 2002....
- Improvement of bone in patients with osteogenesis imperfecta treated with pamidronate-lessons from biochemistryCraig B Langman
J Clin Endocrinol Metab 88:984-5. 2003
- L-carnitine treatment of anemiaThomas A Golper
Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Am J Kidney Dis 41:S27-34. 2003....
- Synthesis of vitamin D in skin after burnsGordon L Klein
Department of Paediatrics, University of Texas Medical Branch, Galveston TX 77555 0352, USA
Lancet 363:291-2. 2004..Low serum 25-hydroxyvitamin D concentrations were also found. We conclude that vitamin D supplementation is necessary after burn injury...
- Renal function and bisphosphonate safetySusan M Ott
J Bone Miner Res 23:453-4; author reply 455. 2008
- Effect of a single course of isotretinoin therapy on bone mineral density in adolescent patients with severe, recalcitrant, nodular acneJohn J DiGiovanna
Division of Dermatopharmacology, Department of Dermatology, Brown Medical School Rhode Island Hospital, Providence, RI 02903, USA
J Am Acad Dermatol 51:709-17. 2004..The effect of short-term (4-5 months) therapy at the lower dose recommended for acne on bone development in younger, growing adolescent (12-17 years) patients has not been well studied...
- The state of pediatric bone: summary of the ASBMR pediatric bone initiativeGordon L Klein
University of Texas Medical Branch, Galveston, USA
J Bone Miner Res 20:2075-81. 2005