M J LaDu
Affiliation: Northwestern University
- Lipoproteins in the central nervous systemM J LaDu
Department of Pathology, University of Chicago, Illinois, USA
Ann N Y Acad Sci 903:167-75. 2000..Therefore, we hypothesize that the protection from A beta-induced neurotoxicity afforded by apoE3 may result from clearance of the peptide by SDS-stable apoE3:A beta complex formation and uptake by apoE receptors...
- Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responsesM J LaDu
Department of Medicine, Evanston Northwestern Healthcare Research Institute, 1801 Maple Avenue, Suite 6240, Evanston, IL 60201, USA
Neurochem Int 39:427-34. 2001..Thus, apoE receptors appear to translate the presence of extracellular A beta into cellular responses, both initiating glial cell activation and limiting its scope by inducing apoE, an anti-inflammatory agent...
- Association of human, rat, and rabbit apolipoprotein E with beta-amyloidM J LaDu
Department of Pathology, University of Chicago, Illinois 60637, USA
J Neurosci Res 49:9-18. 1997..These binding studies provide one possible explanation for protective effects of both apoE2 and E3 against the development of Alzheimer's disease...
- Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptidesT Tokuda
Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Biochem J 348:359-65. 2000....