M J LaDu

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Lipoproteins in the central nervous system
    M J LaDu
    Department of Pathology, University of Chicago, Illinois, USA
    Ann N Y Acad Sci 903:167-75. 2000
  2. ncbi request reprint Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses
    M J LaDu
    Department of Medicine, Evanston Northwestern Healthcare Research Institute, 1801 Maple Avenue, Suite 6240, Evanston, IL 60201, USA
    Neurochem Int 39:427-34. 2001
  3. ncbi request reprint Association of human, rat, and rabbit apolipoprotein E with beta-amyloid
    M J LaDu
    Department of Pathology, University of Chicago, Illinois 60637, USA
    J Neurosci Res 49:9-18. 1997
  4. pmc Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides
    T Tokuda
    Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Biochem J 348:359-65. 2000

Detail Information

Publications4

  1. ncbi request reprint Lipoproteins in the central nervous system
    M J LaDu
    Department of Pathology, University of Chicago, Illinois, USA
    Ann N Y Acad Sci 903:167-75. 2000
    ..Therefore, we hypothesize that the protection from A beta-induced neurotoxicity afforded by apoE3 may result from clearance of the peptide by SDS-stable apoE3:A beta complex formation and uptake by apoE receptors...
  2. ncbi request reprint Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses
    M J LaDu
    Department of Medicine, Evanston Northwestern Healthcare Research Institute, 1801 Maple Avenue, Suite 6240, Evanston, IL 60201, USA
    Neurochem Int 39:427-34. 2001
    ..Thus, apoE receptors appear to translate the presence of extracellular A beta into cellular responses, both initiating glial cell activation and limiting its scope by inducing apoE, an anti-inflammatory agent...
  3. ncbi request reprint Association of human, rat, and rabbit apolipoprotein E with beta-amyloid
    M J LaDu
    Department of Pathology, University of Chicago, Illinois 60637, USA
    J Neurosci Res 49:9-18. 1997
    ..These binding studies provide one possible explanation for protective effects of both apoE2 and E3 against the development of Alzheimer's disease...
  4. pmc Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides
    T Tokuda
    Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Biochem J 348:359-65. 2000
    ....