Research Topics

Genomes and Genes



Affiliation: Northwestern University
Country: USA


  1. Buitrago Delgado E, Schock E, Nordin K, LaBonne C. A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells. Dev Biol. 2018;444:50-61 pubmed publisher
  2. Rao A, LaBonne C. Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest. Development. 2018;145: pubmed publisher
    ..Together, these findings elucidate a previously uncharacterized role for HDAC activity in establishing the neural crest stem cell state. ..
  3. Groves A, LaBonne C. Setting appropriate boundaries: fate, patterning and competence at the neural plate border. Dev Biol. 2014;389:2-12 pubmed publisher
  4. Buitrago Delgado E, Nordin K, Rao A, Geary L, LaBonne C. NEURODEVELOPMENT. Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells. Science. 2015;348:1332-5 pubmed publisher
    ..We suggest that neural crest cells may have evolved as a consequence of a subset of blastula cells retaining activity of the regulatory network underlying pluripotency. ..
  5. Nordin K, LaBonne C. Sox5 Is a DNA-binding cofactor for BMP R-Smads that directs target specificity during patterning of the early ectoderm. Dev Cell. 2014;31:374-82 pubmed publisher
    ..Our findings identify Sox5 as the long-sought DNA-binding partner for BMP R-Smads essential to plasticity and pattern in the early ectoderm. ..