Research Topics
| Todd A KuikenSummaryAffiliation: Northwestern University Country: USA Publications
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Detail Information
Publications
Targeted reinnervation for enhanced prosthetic arm function in a woman with a proximal amputation: a case studyTodd A Kuiken
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
Lancet 369:371-80. 2007..We developed a technique that used nerve transfers to muscle to develop new electromyogram control signals and nerve transfers to skin, to provide a pathway for cutaneous sensory feedback to the missing hand...
Targeted muscle reinnervation for real-time myoelectric control of multifunction artificial armsTodd A Kuiken
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, 345 E Superior St, Room 1309, Chicago, IL 60611, USA
JAMA 301:619-28. 2009..After reinnervation, these target muscles produce electromyogram (EMG) signals on the surface of the skin that can be measured and used to control prosthetic arms...- Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervationTodd A Kuiken
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University, 345 East Superior Street, Chicago, IL 60611, USA
Proc Natl Acad Sci U S A 104:20061-6. 2007.... - Control of a six degree of freedom prosthetic arm after targeted muscle reinnervation surgeryLaura A Miller
Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Arch Phys Med Rehabil 89:2057-65. 2008..To fit and evaluate the control of a complex prosthesis for a shoulder disarticulation-level amputee with targeted muscle reinnervation... 
A strategy for minimizing the effect of misclassifications during real time pattern recognition myoelectric controlAnn M Simon
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
Conf Proc IEEE Eng Med Biol Soc 2009:1327-30. 2009..These results suggest that using a pattern recognition system with a decision based velocity profile may improve user performance...- Quantifying pattern recognition-based myoelectric control of multifunctional transradial prosthesesGuanglin Li
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Neural Syst Rehabil Eng 18:185-92. 2010.... - Targeted reinnervation in the transfemoral amputee: a preliminary study of surgical techniqueSonya P Agnew
Division of Plastic and Reconstructive Surgery, Northwestern University, Chicago, Ill, USA
Plast Reconstr Surg 129:187-94. 2012..To bring this technique to transfemoral amputees, a comprehensive understanding of the location of motor and sensory nerves is required... - An analysis of EMG electrode configuration for targeted muscle reinnervation based neural machine interfaceHe Huang
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Neural Syst Rehabil Eng 16:37-45. 2008..7+/-4.5%. These outcomes provide important guidelines for practical electrode placement that can promote future clinical application of TMR and EMG PR in the control of multifunctional prostheses... - Occupational therapy protocol for amputees with targeted muscle reinnervationKathy A Stubblefield
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Suite 1309, 345 E Superior St, Chicago, IL 60611, USA
J Rehabil Res Dev 46:481-8. 2009..This material is based on more than 6 years of experience treating patients with TMR in a research setting. Detailed results of this research are reported elsewhere... - Vibrotactile detection thresholds for chest skin of amputees following targeted reinnervation surgeryAimee E Schultz
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
Brain Res 1251:121-9. 2009..The functional limb sensation following targeted reinnervation could be used to provide prosthesis users with a sense of touch... - Improved myoelectric prosthesis control using targeted reinnervation surgery: a case seriesLaura A Miller
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Neural Syst Rehabil Eng 16:46-50. 2008..Performance on timed tests, including the box-and-blocks test and clothespin test, has increased two to six times. Options for new control strategies are discussed... - The effects of increased prosthetic ankle motions on the gait of persons with bilateral transtibial amputationsPo Fu Su
Northwestern University Prosthetics Research Laboratory and Rehabilitation Engineering Research Program, Chicago, Illinois, USA
Am J Phys Med Rehabil 89:34-47. 2010..To determine whether the provision of prosthetic ankle motion improves walking performance in persons with bilateral transtibial amputations... - Gait characteristics of persons with bilateral transtibial amputationsPo Fu Su
Department of Biomedical Engineering, Robert R McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL, USA
J Rehabil Res Dev 44:491-501. 2007..These results demonstrate the deficiencies in current prosthetic componentry and suggest that further research is needed to enhance prosthesis function and improve gait in persons with amputations... - Independence of myoelectric control signals examined using a surface EMG modelMadeleine M Lowery
Research Department, Rehabilitation Institute of Chicago, Chicago, IL 60611 4496, USA
IEEE Trans Biomed Eng 50:789-93. 2003..More focal control signals can be obtained, at the expense of increased variability, by using the mean square value, rather than the root mean square or average rectified value... - Decoding a new neural machine interface for control of artificial limbsPing Zhou
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, IL, USA
J Neurophysiol 98:2974-82. 2007..In addition, the results demonstrate that the central motor control system is capable of eliciting complex efferent commands for a missing limb, in the absence of peripheral feedback and without retraining of the pathways involved... - Volume conduction in an anatomically based surface EMG modelMadeleine M Lowery
Sensory Motor Performance Program Laboratory, Research Department, Rehabilitation Institute of Chicago, Chicago, IL 60611 4496, USA
IEEE Trans Biomed Eng 51:2138-47. 2004..However, if the objective is to examine more qualitative features of the surface EMG signal, then an idealized volume conductor model with appropriate tissue thicknesses provides a close approximation... - Targeted reinnervation to improve prosthesis control in transhumeral amputees. A report of three casesGregory A Dumanian
Division of Plastic Surgery, Department of Surgery, Feinberg School of Medicine, Northwestern University, 675 North St. Clair Street, 19th Floor Galter, Suite 250, Chicago, IL 60611, USA
J Bone Joint Surg Am 90:393-400. 2008 - Sensory capacity of reinnervated skin after redirection of amputated upper limb nerves to the chestPaul D Marasco
Neural Engineering Center for Artificial Limbs Rehabilitation Institute of Chicago, 345 E Superior Street, Chicago, IL 60611, USA
Brain 132:1441-8. 2009.... - Development of a model osseo-magnetic link for intuitive rotational control of upper-limb prosthesesElliott J Rouse
Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA
IEEE Trans Neural Syst Rehabil Eng 19:213-20. 2011..Adjustments in sensor placement may reduce these errors. The results demonstrate that the OML is a feasible solution for providing prosthesis rotation control while preserving rotational proprioception... - Determining the optimal window length for pattern recognition-based myoelectric control: balancing the competing effects of classification error and controller delayLauren H Smith
Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 USA
IEEE Trans Neural Syst Rehabil Eng 19:186-92. 2011..For the system employed in this study, the optimal window length was found to be between 150 and 250 ms, which is within acceptable controller delays for conventional multistate amplitude controllers... - Improved myoelectric prosthesis control accomplished using multiple nerve transfersJohn B Hijjawi
Department of Surgery, Division of Plastic Surgery, Feinberg School of Medicine, Northwestern University, and the Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, Ill 60610, USA
Plast Reconstr Surg 118:1573-8. 2006..This is done using standard techniques of nerve and flap surgery, and without any implantable devices... - Design and validation of a platform robot for determination of ankle impedance during ambulationElliott J Rouse
Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA
Conf Proc IEEE Eng Med Biol Soc 2011:8179-82. 2011..The estimates obtained by the proposed platform robot compare favorably to those published in the literature. Future work will investigate the impedance of the ankle during ambulation for powered prosthesis controller development... - Target Achievement Control Test: evaluating real-time myoelectric pattern-recognition control of multifunctional upper-limb prosthesesAnn M Simon
Center for Bionic Medicine, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
J Rehabil Res Dev 48:619-27. 2011..These results highlight the need for closed-loop performance measures and demonstrate that the TAC Test is a useful and more challenging tool to test real-time pattern-recognition performance... - Finite-element time-domain algorithms for modeling linear Debye and Lorentz dielectric dispersions at low frequenciesNikolay S Stoykov
Rehabilitation Institute of Chicago, IL 60611, USA
IEEE Trans Biomed Eng 50:1100-7. 2003..Potential applications include FETD modeling of electromyography, functional electrical stimulation, defibrillation, and effects of lightning and impulsive electric shock... - Frequency- and time-domain FEM models of EMG: capacitive effects and aspects of dispersionNikolay S Stoykov
Rehabilitation Institute of Chicago, IL 60611, USA
IEEE Trans Biomed Eng 49:763-72. 2002..It is clear that there is a need to establish accurate values of both conductivity and permittivity for human muscle tissue in vivo in order to quantify the influence of capacitance and dispersion on the EMG signal... - EMG pattern recognition control of multifunctional prostheses by transradial amputeesGuanglin Li
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago and Department of Physical Medicine and Rehabilitation, Northwestern University, IL 60611, USA
Conf Proc IEEE Eng Med Biol Soc 2009:6914-7. 2009..These results suggest that the muscles in the residual forearm may produce sufficient myoelectric information to allow the six basic motion control, but insufficient information for more hand functions with fine finger movements... - The effect of ECG interference on pattern-recognition-based myoelectric control for targeted muscle reinnervated patientsLevi Hargrove
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Biomed Eng 56:2197-201. 2009..High-pass filtering at approximately 100 Hz appears to effectively mitigate the effect of ECG interference... - A finite-element analysis of the effect of muscle insulation and shielding on the surface EMG signalNikolay S Stoykov
Rehabilitation Institute of Chicago, 345 East Superior Street, Room 1436, IL 60611, USA
IEEE Trans Biomed Eng 52:117-21. 2005..The results suggest that the crosstalk between insulated or shielded muscles is small but that it increases with increasing subcutaneous fat. The findings may be useful in the control of multifunctional prostheses... - Use of two-axis joystick for control of externally powered shoulder disarticulation prosthesesRobert D Lipschutz
Center for Bionic Medicine, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
J Rehabil Res Dev 48:661-7. 2011..Additionally, two motions (one in each axis) could be controlled simultaneously. This pilot study provides valuable insight into an effective means of controlling high-level, externally powered prostheses with a two-axis joystick... - Study of stability of time-domain features for electromyographic pattern recognitionDennis Tkach
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, 345 E, Superior Street, Suite 1309, Chicago, IL 60611, USA
J Neuroeng Rehabil 7:21. 2010.... - Examination of force discrimination in human upper limb amputees with reinnervated limb sensation following peripheral nerve transferJonathon W Sensinger
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Neural Syst Rehabil Eng 17:438-44. 2009..09 and 0.21. WR of reinnervated skin for TR subjects were within the 95% confidence interval of the control group. These data suggest that subjects with targeted reinnervation have unimpaired ability to discriminate gradations in force... - Targeted reinnervation for transhumeral amputees: current surgical technique and update on resultsGregory A Dumanian
Division of Plastic Surgery, Northwestern University Feinberg School of Medicine, 675 North St Clair, Suite 19 250, Chicago, IL 60610, USA
Plast Reconstr Surg 124:863-9. 2009..Targeted reinnervation in upper extremity transhumeral amputees can improve control and dexterity of myoelectric prostheses. The operation as described previously required a long residual limb and the presence of a brachialis muscle... - Adaptive pattern recognition of myoelectric signals: exploration of conceptual framework and practical algorithmsJonathon W Sensinger
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Neural Syst Rehabil Eng 17:270-8. 2009..Supervised adaptation should be considered for incorporation into any clinically viable pattern recognition controller, and unsupervised adaptation should receive renewed interest in order to provide transparent adaptation... - Eliminating cardiac contamination from myoelectric control signals developed by targeted muscle reinnervationPing Zhou
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL, USA
Physiol Meas 27:1311-27. 2006..The feasibility of the different methods for clinical application was also investigated with consideration of the clinical speed requirements and memory limitations of commercial prosthesis controllers... - Improving myoelectric pattern recognition robustness to electrode shift by changing interelectrode distance and electrode configurationAaron J Young
Center for Bionic Medicine, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Biomed Eng 59:645-52. 2012..01) reduced sensitivity to electrode shift compared to a traditional time-domain feature set... - Real time ECG artifact removal for myoelectric prosthesis controlPing Zhou
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL, USA
Physiol Meas 28:397-413. 2007..Aiming at clinical application, the optimal parameter assignment for each method was determined on the basis of the performance using the suite of testing signals with various ECG/EMG ratios... - Robotic touch shifts perception of embodiment to a prosthesis in targeted reinnervation amputeesPaul D Marasco
Neural Engineering Centre for Artificial Limbs, Rehabilitation Institute of Chicago, 345 E Superior St Rm 1309 Chicago, IL 60611, USA
Brain 134:747-58. 2011..We suggest that this may help amputees to more effectively incorporate an artificial limb into their self image, providing the possibility that a prosthesis becomes not only a tool, but also an integrated body part... - A simulation study to examine the use of cross-correlation as an estimate of surface EMG cross talkMadeleine M Lowery
Rehabilitation Institute of Chicago, and Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago 60611, USA
J Appl Physiol 94:1324-34. 2003..Furthermore, it is possible that a high correlation between surface EMG signals may reflect an association between motor unit firing times, for example due to motor unit synchronization... - Expert opinions on success factors for upper-limb prosthesesAimee E Schultz
Department of Mechanical Engineering, Northwestern University, Evanston, IL, USA
J Rehabil Res Dev 44:483-9. 2007..Cosmesis was consistently reported as being less important than comfort and function, and shape was considered more important than color... - The effects of targeted muscle reinnervation on neuromas in a rabbit rectus abdominis flap modelPeter S Kim
Division of Plastic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
J Hand Surg Am 37:1609-16. 2012..In addition, by virtue of the nerve coaptation, the morphology of the previous amputation neuroma would become more like that of an in-continuity neuroma... - A quantitative evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromasJason H Ko
Department of Surgery, Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
J Brachial Plex Peripher Nerve Inj 6:8. 2011..abstract:.. - Neural interfaces for control of upper limb prostheses: the state of the art and future possibilitiesAimee E Schultz
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
PM R 3:55-67. 2011..In this review, we discuss the current state of the art of neural interfaces, particularly those that may find application within the prosthetics field... - The effects of electrode size and orientation on the sensitivity of myoelectric pattern recognition systems to electrode shiftAaron J Young
Center for Bionic Medicine, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
IEEE Trans Biomed Eng 58:2537-44. 2011..One clinically important result was that a combination of longitudinal and transverse electrodes yielded high controllability with and without electrode shift using only four physical electrode pole locations... - Comparison of electromyography and force as interfaces for prosthetic controlElaine A Corbett
Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA
J Rehabil Res Dev 48:629-41. 2011..The results may be useful for the design of prostheses and prosthetic controllers... - Modeling of prosthetic limb rotation control by sensing rotation of residual arm boneGuanglin Li
Shandong University, Jinan 250100, China
IEEE Trans Biomed Eng 55:2134-42. 2008..This pilot study provides important guidelines for developing a practical interface between the residual bone rotation and the prosthesis for control of prosthetic rotation... - Amputation with median nerve redirection (targeted reinnervation) reactivates forepaw barrel subfield in ratsPaul D Marasco
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
J Neurosci 30:16008-14. 2010..Targeted reinnervation offers the opportunity to examine the cortical plasticity effects when behaviorally important sensory afferents are redirected from their original location to a new skin surface on a different part of the body... - A computational model for stress reduction at the skin-implant interface of osseointegrated prosthesesSrinivasu Yerneni
Center for Bionic Medicine, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
J Biomed Mater Res A 100:911-7. 2012..The findings in this study suggests that surgical techniques could stabilize the skin-implant interface, thus enhancing a skin-to-bone seal around the percutaneous device and minimizing infection... - The effect of perturbation onset timing and length on tripping recovery strategiesCamila Shirota
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
Conf Proc IEEE Eng Med Biol Soc 2011:7833-6. 2011..These results show that perturbation length affects recovery strategy selection in response to trips... - Novel model for end-neuroma formation in the amputated rabbit forelimbPeter S Kim
Department of Surgery, Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
J Brachial Plex Peripher Nerve Inj 5:6. 2010..To further elucidate the pathogenic process in amputation neuroma formation, we created a reproducible, well-tolerated rabbit forelimb amputation model... - Differences in gait characteristics between persons with bilateral transtibial amputations, due to peripheral vascular disease and trauma, and able-bodied ambulatorsPo Fu Su
Department of Biomedical Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL, USA
Arch Phys Med Rehabil 89:1386-94. 2008.... - A multiple-layer finite-element model of the surface EMG signalMadeleine M Lowery
Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestem University, IL 60611, USA
IEEE Trans Biomed Eng 49:446-54. 2002.... - Computerized biofeedback knee goniometer: acceptance and effect on exercise behavior in post-total knee arthroplasty rehabilitationTodd A Kuiken
Rehabilitation Institute of Chicago, 345 E Superior Street, Rm 1124, Chicago, IL 60611, USA
Arch Phys Med Rehabil 85:1026-30. 2004..To assess device accuracy, patient acceptance, and effect of a computerized biofeedback knee goniometer (CBG), on patients' compliance with active range of motion (AROM) exercises after total knee arthroplasty (TKA)... - Simulation of intramuscular EMG signals detected using implantable myoelectric sensors (IMES)Madeleine M Lowery
School of Electrical, Electronic and Mechanical Engineering, University College Dublin, Belfield, Dublin 4, Ireland
IEEE Trans Biomed Eng 53:1926-33. 2006..The estimated detection radius of the IMES electrode, assuming a cylindrical muscle cross section, was 4.8, 6.2, and 7.5 mm for electrode orientations of 0 degree, 22.5 degrees, and 45 degrees with respect to the muscle fiber direction... - Neural machine interfaces for controlling multifunctional powered upper-limb prosthesesKengo Ohnishi
Northwestern University Prosthetic Research Laboratory Research Associate, Oita University, Department of Welfare Engineering, Faculty of Engineering700 Dannoharu, Oita, 8701192, Japan
Expert Rev Med Devices 4:43-53. 2007..In addition, studies on interfaces using muscle acoustic and mechanical properties and the problem of interfacing sensory information to the nervous system are discussed...