Research Topics
| Ravi KalhanSummaryAffiliation: Northwestern University Country: USA Publications
Research Grants
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Detail Information
Publications
Head CT is of limited diagnostic value in critically ill patients who remain unresponsive after discontinuation of sedationJay S Balachandran
Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
BMC Anesthesiol 9:3. 2009..We sought to determine the diagnostic value of head computed tomography (CT) in mechanically ventilated patients who remain unresponsive after discontinuation of sedation...
A 48-year-old woman with skin lesions, renal masses, and spontaneous pneumothoraxRavi Kalhan
Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, 240 E Huron, McGaw M-300, Chicago, IL 60611, USA
Chest 131:624-7. 2007
A mechanism of benefit of soy genistein in asthma: inhibition of eosinophil p38-dependent leukotriene synthesisR Kalhan
Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Clin Exp Allergy 38:103-12. 2008..Dietary intake of the soy isoflavone genistein is associated with reduced severity of asthma, but the mechanisms responsible for this effect are unknown...
Systemic inflammation in young adults is associated with abnormal lung function in middle ageRavi Kalhan
Asthma Chronic Obstructive Pulmonary Disease Program, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
PLoS ONE 5:e11431. 2010..Whether systemic inflammation in healthy young adults is associated with future impairment in lung health is uncertain...
Lung function in young adults predicts airflow obstruction 20 years laterRavi Kalhan
Northwestern University, Chicago, IL 60611, USA
Am J Med 123:468.e1-7. 2010..To determine in a prospective cohort of generally healthy young adults the influence of early adult lung function on the presence of airflow obstruction in middle age...
An integrated approach to the medical treatment of chronic obstructive pulmonary diseaseSharon R Rosenberg
Asthma and COPD Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Med Clin North Am 96:811-26. 2012..Newer therapies have been developed with the specific purpose of reducing COPD exacerbations and should be prescribed to individuals who have evidence of recurrent exacerbations despite maximal inhaled maintenance medications...
Effect of obesity on asthma phenotype is dependent upon asthma severityStacy Raviv
Department of Pulmonary and Critical Care Medicine, NorthShore University Health System, Evanston, IL, USA
J Asthma 48:98-104. 2011..Understanding how obesity affects asthmatics of differing severity can provide insights into the pathogenesis of asthma in the obese and a rationale for the therapeutic approach to such patients...
Right heart structural changes are independently associated with exercise capacity in non-severe COPDMichael J Cuttica
Pulmonary Hypertension Program, Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, Illinois, United States of America
PLoS ONE 6:e29069. 2011..Data regarding the functional consequence of PH in less severe COPD are limited. Whether echocardiographic evidence of right sided heart pathology is associated with functional outcomes in patients with non-severe COPD is unknown...
A 23-year-old woman with sudden-onset dyspnea and chest pain penetrating to the backJeff S Kwon
Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, 240 E Huron, McGaw M-300, Chicago, IL 60611, USA
Chest 133:574-8. 2008
Incidence, treatment options, and outcomes of lung cancer in patients with chronic obstructive pulmonary diseaseClara Schroedl
Asthma and COPD Program, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Curr Opin Pulm Med 18:131-7. 2012..This review describes the current understanding of the incidence, mechanism of association, treatment options, and outcome for lung cancer with COPD...
Spirometry guidelines influence lung function results in a longitudinal study of young adultsLewis J Smith
Northwestern University, Chicago, IL 60611, USA
Respir Med 104:858-64. 2010..Epidemiology studies initiated before adoption of the 1987 American Thoracic Society (ATS) guidelines typically used a 1 or 2 s plateau on the volume-time curve, not a minimum test duration of 6 s, to terminate a test...
Hyperinflation is associated with lower sleep efficiency in COPD with co-existent obstructive sleep apneaJeff S Kwon
Department of Neurology, Center for Sleep and Circadian Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
COPD 6:441-5. 2009..The mechanisms underlying this observation are uncertain. We speculate that therapies aimed at reducing lung hyperinflation may improve sleep quality in patients with overlap syndrome...
Lung cancer in chronic obstructive pulmonary disease: enhancing surgical options and outcomesStacy Raviv
Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, 676 N St Clair Street, Suite 1400, Chicago, IL 60611, USA
Am J Respir Crit Care Med 183:1138-46. 2011....
Categorization and impact of pulmonary hypertension in patients with advanced COPDMichael J Cuttica
Pulmonary Hypertension Program, Division of Pulmonary and Critical Care Medicine, Northwestern University, Suite 1400, Chicago, IL 60611, USA
Respir Med 104:1877-82. 2010..The functional significance of pulmonary hypertension (PH) in COPD is unclear. The purpose of the study was to define the prevalence, severity and associated functional impact of PH in patients with severe COPD listed for lung transplant...
Biomarkers in chronic obstructive pulmonary diseaseSharon R Rosenberg
Asthma and COPD Program, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, 676 N St Clair Street, Chicago, IL 60611, USA
Transl Res 159:228-37. 2012..So far, no single biomarker in COPD warrants wide acceptance emphasizing the need for future investigation of biomarkers in large-scale longitudinal studies...
Research Grants
- Genistein and Asthma PathogenesisRavi Kalhan; Fiscal Year: 2006..Exploring these mechanisms will expand the scientific rationale for tyrosine kinase inhibition as a therapeutic approach to asthmatic airway remodeling, and justify further study of the therapeutic role of soy isoflavones. ..
