P J Kahrilas

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Esophageal dysphagia
    P J Kahrilas
    Department of Medicine, Northwestern University, Chicago, Illinois
    Acta Otorhinolaryngol Belg 48:171-90. 1994
  2. ncbi request reprint The effects of tegaserod (HTF 919) on oesophageal acid exposure in gastro-oesophageal reflux disease
    P J Kahrilas
    Northwestern University Medical School, Chicago, Illinois 60611, USA
    Aliment Pharmacol Ther 14:1503-9. 2000
  3. ncbi request reprint Comparison of esophageal acid exposure at 1 cm and 6 cm above the squamocolumnar junction using the Bravo pH monitoring system
    J E Pandolfino
    Northwestern University s Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Dis Esophagus 19:177-82. 2006
  4. ncbi request reprint Increased frequency of transient lower esophageal sphincter relaxation induced by gastric distention in reflux patients with hiatal hernia
    P J Kahrilas
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA
    Gastroenterology 118:688-95. 2000
  5. pmc Manometric features of eosinophilic esophagitis in esophageal pressure topography
    S Roman
    Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 23:208-14, e111. 2011
  6. pmc Transient lower oesophageal sphincter relaxation in achalasia: everything but LOS relaxation
    M A Kwiatek
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 21:1294-e123. 2009
  7. pmc The contractile deceleration point: an important physiologic landmark on oesophageal pressure topography
    J E Pandolfino
    Division of Gastroenterology, Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611, USA
    Neurogastroenterol Motil 22:395-400, e90. 2010
  8. ncbi request reprint Hiatal hernia size is the dominant determinant of esophagitis presence and severity in gastroesophageal reflux disease
    M P Jones
    Division of Gastroenterology, Northwestern University, Chicago, Illinois, USA
    Am J Gastroenterol 96:1711-7. 2001
  9. pmc Localizing the contractile deceleration point (CDP) in patients with abnormal esophageal pressure topography
    Z Lin
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurogastroenterol Motil 24:972-5. 2012
  10. ncbi request reprint Manometric characteristics of the upper esophageal sphincter recorded with a microsleeve
    C Dire
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611-3008, USA
    Am J Gastroenterol 96:1383-9. 2001

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Esophageal dysphagia
    P J Kahrilas
    Department of Medicine, Northwestern University, Chicago, Illinois
    Acta Otorhinolaryngol Belg 48:171-90. 1994
    ..Finally, current concepts of the pathophysiology and therapy of gastroesophageal reflux disease. Emphasis is placed on the dual sphincter theory of gastroesophageal junction competence and the need for maintenance anti-secretory therapy...
  2. ncbi request reprint The effects of tegaserod (HTF 919) on oesophageal acid exposure in gastro-oesophageal reflux disease
    P J Kahrilas
    Northwestern University Medical School, Chicago, Illinois 60611, USA
    Aliment Pharmacol Ther 14:1503-9. 2000
    ..Tegaserod (HTF 919), a 5-HT4 receptor partial agonist, has prokinetic effects that might be useful in decreasing acid reflux in gastro-oesophageal reflux disease (GERD)...
  3. ncbi request reprint Comparison of esophageal acid exposure at 1 cm and 6 cm above the squamocolumnar junction using the Bravo pH monitoring system
    J E Pandolfino
    Northwestern University s Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Dis Esophagus 19:177-82. 2006
    ..These findings suggest that measurement of acid exposure 1 cm above the SCJ may improve accuracy of pH monitoring by detecting acid reflux events confined to the distal esophagus...
  4. ncbi request reprint Increased frequency of transient lower esophageal sphincter relaxation induced by gastric distention in reflux patients with hiatal hernia
    P J Kahrilas
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA
    Gastroenterology 118:688-95. 2000
    ..This study aimed to determine if hiatal hernia influences vulnerability to reflux and transient lower esophageal sphincter relaxation (tLESR) during gastric distention in patients with gastroesophageal reflux disease (GERD)...
  5. pmc Manometric features of eosinophilic esophagitis in esophageal pressure topography
    S Roman
    Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 23:208-14, e111. 2011
    ..The aims of this study were to evaluate the esophageal pressure topography (EPT) findings in EoE and to compare them with controls and patients with gastro-esophageal disease (GERD)...
  6. pmc Transient lower oesophageal sphincter relaxation in achalasia: everything but LOS relaxation
    M A Kwiatek
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 21:1294-e123. 2009
    ....
  7. pmc The contractile deceleration point: an important physiologic landmark on oesophageal pressure topography
    J E Pandolfino
    Division of Gastroenterology, Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611, USA
    Neurogastroenterol Motil 22:395-400, e90. 2010
    ..This study aimed to correlate oesophageal bolus transit with features of oesophageal pressure topography (OPT) plots and establish OPT metrics for accurately measuring peristaltic velocity...
  8. ncbi request reprint Hiatal hernia size is the dominant determinant of esophagitis presence and severity in gastroesophageal reflux disease
    M P Jones
    Division of Gastroenterology, Northwestern University, Chicago, Illinois, USA
    Am J Gastroenterol 96:1711-7. 2001
    ..97, p = 0.0146) as significant predictors of erosive esophagitis. CONCLUSION: Esophagitis severity is best predicted by hiatal hernia size and lower esophageal sphincter pressure. Of these, hiatal hernia size is the strongest predictor...
  9. pmc Localizing the contractile deceleration point (CDP) in patients with abnormal esophageal pressure topography
    Z Lin
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurogastroenterol Motil 24:972-5. 2012
    ..This study aimed to test the tML method for localizing CDP in patients with abnormal motility...
  10. ncbi request reprint Manometric characteristics of the upper esophageal sphincter recorded with a microsleeve
    C Dire
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611-3008, USA
    Am J Gastroenterol 96:1383-9. 2001
    ..Volume modulation of deglutitive UES relaxation is demonstrable with a microsleeve, albeit with less precision than with a solid-state transducer...
  11. ncbi request reprint Slimline vs. glass pH electrodes: what degree of accuracy should we expect?
    J E Pandolfino
    Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611, USA
    Aliment Pharmacol Ther 23:331-40. 2006
    ..Ambulatory pH monitoring is considered the gold standard for measuring oesophageal acid exposure, however, data comparing antimony and glass electrodes are limited...
  12. pmc Esophagogastric Junction pressure morphology: comparison between a station pull-through and real-time 3D-HRM representation
    F Nicodème
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 25:e591-8. 2013
    ..Recent technological advances in miniaturization and electronics have led to the development of a novel device that may overcome these challenges...
  13. pmc Distensibility of the esophagogastric junction assessed with the functional lumen imaging probe (FLIP™) in achalasia patients
    J E Pandolfino
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurogastroenterol Motil 25:496-501. 2013
    ..The aim of this study is to apply this tool to the assessment of the EGJ in untreated and treated achalasia patients and to compare EGJ distensibility with other diagnostic tools utilized in managing achalasia...
  14. pmc The effect of a sitting vs supine posture on normative esophageal pressure topography metrics and Chicago Classification diagnosis of esophageal motility disorders
    Y Xiao
    Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 24:e509-16. 2012
    ..Our aims were to establish normative esophageal pressure topography data for the sitting position and to determine the effect of applying those norms to Chicago Classification diagnoses...
  15. pmc Optimizing the swallow protocol of clinical high-resolution esophageal manometry studies
    Y Xiao
    Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 24:e489-96. 2012
    ..The aim of the study was to assess whether upright and provocative swallows (PS) provided important information beyond that obtained from the standard supine manometric protocol...
  16. pmc Refining the criterion for an abnormal Integrated Relaxation Pressure in esophageal pressure topography based on the pattern of esophageal contractility using a classification and regression tree model
    Zhiyue Lin
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 24:e356-63. 2012
    ..However, because the IRP value is also influenced by distal esophageal contractility, we hypothesized that its normal limits should vary with different patterns of contractility...
  17. ncbi request reprint Manometric heterogeneity in patients with idiopathic achalasia
    I Hirano
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA
    Gastroenterology 120:789-98. 2001
    ..Furthermore, such variants provide important clues into the pathophysiology of this rare disorder...
  18. pmc An alginate-antacid formulation (Gaviscon Double Action Liquid) can eliminate or displace the postprandial 'acid pocket' in symptomatic GERD patients
    M A Kwiatek
    Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 St Clair Street, Chicago, IL 60611 2951, USA
    Aliment Pharmacol Ther 34:59-66. 2011
    ..By creating a low density gel 'raft' that floats on top of gastric contents, alginate-antacid formulations may neutralise the 'acid pocket'...
  19. doi request reprint Esophageal symptoms questionnaire for the assessment of dysphagia, globus, and reflux symptoms: initial development and validation
    M A Kwiatek
    Esophageal Disorders Research Center, Division of Gastroenterology, Department of Medicine, Northwestern University, Feinberg School of Medicine, 676 N St Clair Street, Chicago, Illinois, USA
    Dis Esophagus 24:550-9. 2011
    ..As a tool measuring more than one esophageal symptom, ESQ could guide patient management by indicating which of the coexisting symptoms needs to be addressed first...
  20. pmc 3D-high resolution manometry of the esophagogastric junction
    M A Kwiatek
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 23:e461-9. 2011
    ..This study aimed to define EGJ pressure morphology relative to the squamocolumnar junction (SCJ) during respiration with 3D-high resolution manometry (3D-HRM)...
  21. pmc Automated calculation of the distal contractile integral in esophageal pressure topography with a region-growing algorithm
    Z Lin
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 24:e4-10. 2012
    ..The aim of this study was to develop an automated algorithm calculating DCI...
  22. ncbi request reprint Upper sphincter function during transient lower oesophageal sphincter relaxation (tLOSR); it is mainly about microburps
    J E Pandolfino
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Neurogastroenterol Motil 19:203-10. 2007
    ..Whether or not GORD patients with extra-oesophageal symptoms exhibit an exaggeration of the UOS relaxation response during reflux is yet to be determined...
  23. pmc Oesophageal peristaltic transition zone defects: real but few and far between
    S K Ghosh
    Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurogastroenterol Motil 20:1283-90. 2008
    ..8%). Although far less common than distal peristaltic or OGJ abnormailites, TZ defects may be related to dysphagia in a minority of patients (<4% in this series) and should be considered a distinct oesophageal motility disorder...
  24. ncbi request reprint Esophageal motility disorders: current concepts of pathogenesis and treatment
    P J Kahrilas
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611 3053, USA
    Can J Gastroenterol 14:221-31. 2000
    ..This clarity diminishes progressively for DES and nonspecific esophageal motility disorders...
  25. pmc Acid reflux event detection using the Bravo wireless versus the Slimline catheter pH systems: why are the numbers so different?
    J E Pandolfino
    Division of Gastroenterology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Suite 1400, Chicago, Illinois 60611, USA
    Gut 54:1687-92. 2005
    ..This study analysed the relative accuracy of the Bravo wireless and the Slimline catheter-Mark III Digitrapper pH systems in the detection of acid reflux events...
  26. ncbi request reprint Does the Bravo pH capsule affect esophageal motor function?
    J E Pandolfino
    Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Dis Esophagus 20:406-10. 2007
    ..However, capsule presence was associated with a locus of augmented peristalsis and this phenomenon was most evident in subjects who perceived the presence of the Bravo capsule...
  27. pmc The role of hiatus hernia in GERD
    P J Kahrilas
    Department of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Yale J Biol Med 72:101-11. 1999
    ..Thus, although hiatus hernia may or may not be an initiating factor at the inception of reflux disease, it clearly can act as a sustaining factor accounting for the frequently observed chronicity of the disease...
  28. ncbi request reprint Management of GERD: medical versus surgical
    P J Kahrilas
    Department of Medicine, Northwestern University Medical School, Chicago, IL 60611, USA
    Semin Gastrointest Dis 12:3-15. 2001
    ..However, regardless of the motivation for pursuing surgical management, patients must be advised of potential suboptimal results and the irreversibility of the procedure...
  29. ncbi request reprint Parameters for quantifying bolus retention with high-resolution impedance manometry
    Z Lin
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurogastroenterol Motil 26:929-36. 2014
    ..This study aimed to develop a methodology for quantifying esophageal bolus retention using a high-resolution esophageal impedance topography (EIT) technique...
  30. doi request reprint Impact of persistent, frequent regurgitation on quality of life in heartburn responders treated with acid suppression: a multinational primary care study
    P J Kahrilas
    Division of Gastroenterology and Hepatology, Northwestern University, Chicago, IL, USA
    Aliment Pharmacol Ther 37:1005-10. 2013
    ..In gastro-oesophageal reflux disease (GERD), heartburn responds well to acid suppression, but regurgitation is a common cause of incomplete treatment response...
  31. pmc Regional variation in distal esophagus distensibility assessed using the functional luminal imaging probe (FLIP)
    Z Lin
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurogastroenterol Motil 25:e765-71. 2013
    ..This study aimed to evaluate the spatial variation in esophageal distensibility in normal subjects using a novel multichannel functional luminal imaging probe (FLIP)...
  32. pmc High-resolution manometry in clinical practice: utilizing pressure topography to classify oesophageal motility abnormalities
    J E Pandolfino
    Department of Medicine, Northwestern University, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 21:796-806. 2009
    ..It is our expectation that modification of this classification scheme will continue to occur and this should further clarify the utility of pressure topography plotting in assessing oesophageal motility disorders...
  33. ncbi request reprint Esomeprazole improves healing and symptom resolution as compared with omeprazole in reflux oesophagitis patients: a randomized controlled trial. The Esomeprazole Study Investigators
    P J Kahrilas
    Department of Gastroenterology and Hepatology, Northwestern University Medical School, Chicago, IL 60611 3008, USA
    Aliment Pharmacol Ther 14:1249-58. 2000
    ..The pharmacologic profile of the new proton pump inhibitor esomeprazole has demonstrated advantages over omeprazole that suggest clinical benefits for patients with acid-related disease...
  34. ncbi request reprint Measuring EGJ opening patterns using high resolution intraluminal impedance
    J E Pandolfino
    Department of Medicine, Northwestern University, The Feinberg School of Medicine, 676 N St Clair Street, Suite 1400, Chicago, IL 60611, USA
    Neurogastroenterol Motil 17:200-6. 2005
    ..These results support that impedance monitoring can be adapted to identify sphincter opening, to distinguish sphincter opening from sphincter relaxation, and to determine luminal contents during the opening period...
  35. doi request reprint Physiology of the LES
    M A Kwiatek
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Dis Esophagus 25:286-91. 2012
    ..The purpose of this review is to consider the neuromuscular mechanism of LES contractility both by itself and in relation to the esophagogastric junction (EGJ) complex in order to appreciate the intricacies of EGJ valvular function...
  36. ncbi request reprint Supraesophageal complications of reflux disease and hiatal hernia
    P J Kahrilas
    Department of Medicine, Division of Gastroenterology and Hepatology, Northwestern University Medical School, 303 E. Chicago Avenue, Searle Building 10th Floor, Chicago, IL 60611, USA
    Am J Med 111:51S-55S. 2001
    ..The dynamic anatomy of the EGJ highlights the difficulty of defining hiatal hernia and of elucidating the relation between hiatal hernia, the diaphragmatic hiatus, the LES, and GERD, including supraesophageal reflux...
  37. ncbi request reprint The effect of glucagon-induced gastric relaxation on TLOSR frequency
    H Y Chang
    Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Neurogastroenterol Motil 15:3-8. 2003
    ..Despite causing substantial proximal stomach relaxation, glucagon did not increase TLOSR frequency. This suggests that the relevant gastric mechanoreceptors responsible for triggering TLOSRs do not respond to passive elongation...
  38. doi request reprint Do patients with globus sensation respond to hypnotically assisted relaxation therapy? A case series report
    J L Kiebles
    Center for Psychosocial Research in GI, and Esophageal Disorders Research Center, Northwestern University, Feinberg School of Medicine, Division of Gastroenterology, Chicago, IL, USA
    Dis Esophagus 23:545-53. 2010
    ..UES function was unaffected. We suggest that HAR therapy is an acceptable and useful intervention for patients with globus sensation...
  39. ncbi request reprint Review article: is stringent control of gastric pH useful and practical in GERD?
    P J Kahrilas
    North Western University, Feinberg School of Medicine, Division of Gastroenterology, Chicago, IL 60611, USA
    Aliment Pharmacol Ther 20:89-94; discussion 95-6. 2004
    ....
  40. ncbi request reprint Review article: oesophageal pH monitoring--technologies, interpretation and correlation with clinical outcomes
    P J Kahrilas
    Division of Gastroeneterology, Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611, USA
    Aliment Pharmacol Ther 22:2-9. 2005
    ..More research is needed to determine whether the detection of reflux events with Bravo will provide a good correlation with symptom episodes...
  41. doi request reprint Evaluation of the esophagogastric junction using high resolution manometry and esophageal pressure topography
    P J Kahrilas
    Department of Medicine, Division of Gastroenterology and Hepatology, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Neurogastroenterol Motil 24:11-9. 2012
    ....
  42. doi request reprint Eosinophilic oesophagitis in adults
    N Gonsalves
    Division of Gastroenterology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 2951, USA
    Neurogastroenterol Motil 21:1017-26. 2009
    ..This review highlights recent insights into EoE in adults although, clearly, much of the available data overlap with pediatrics and, occasionally, with eosinophilic gastroenteritis...
  43. doi request reprint Utilization of wireless pH monitoring technologies: a summary of the proceedings from the Esophageal Diagnostic Working Group
    J E Richter
    Esophageal Diagnostic Working Group, Digestive Disease Week 2011, Chicago, Illinois, USA
    Dis Esophagus 26:755-65. 2013
    ....
  44. pmc Gatekeeper reflux repair system; a mechanistic hypothesis
    P J Kahrilas
    Northwestern University, Feinberg School of Medicine, Division of Gastroenterology, Department of Medicine, 676 N St Clair Street, Suite 1400, Chicago, Illinois 60611, USA
    Gut 54:179-80. 2005
  45. ncbi request reprint Impaired egress rather than increased access: an important independent predictor of erosive oesophagitis
    M P Jones
    Division of Gastroenterology and Hepatology, Northwestern University Medical School, Chicago, IL 60611, USA
    Neurogastroenterol Motil 14:625-31. 2002
    ..Increased oesophageal acid exposure in oesophagitis is attributable to impaired acid clearance and the greatest impairments in refluxate clearance occur in patients with large hiatal hernias...
  46. ncbi request reprint Review article: gastro-oesophageal reflux disease as a functional gastrointestinal disorder
    P J Kahrilas
    Northwestern University, Feinberg School of Medicine, Department of Medicine, Division of Gastroenterology, Chicago, IL 60611 2951, USA
    Aliment Pharmacol Ther 20:50-5. 2004
    ....
  47. ncbi request reprint Reduced tLESR elicitation in response to gastric distension in fundoplication patients
    R C H Scheffer
    Gastrointestinal Research Unit, Departments of Surgery and Gastroenterology, University Medical Center, 3508 GA Utrecht, The Netherlands
    Am J Physiol Gastrointest Liver Physiol 284:G815-20. 2003
    ..This suggests that the receptive field for triggering tLESRs is contained within a wider field for elicitation of gastric receptive relaxation and that only the first is affected by fundoplication...
  48. pmc Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux
    D Sifrim
    Centre for Gastroenterological Research, Faculty of Medicine, Catholic University of Leuven, Belgium
    Gut 53:1024-31. 2004
    ..Here, a summary of their conclusions and recommendations of how to achieve the best results from the various techniques now available for reflux measurement is presented...
  49. ncbi request reprint Distinct patterns of oesophageal shortening during primary peristalsis, secondary peristalsis and transient lower oesophageal sphincter relaxation
    G Shi
    Department of Medicine, North Western University Medical School, Chicago, IL 60611, USA
    Neurogastroenterol Motil 14:505-12. 2002
    ..During TLOSR, significant elevation of the SCJ occurred only after LOS opening, suggesting that this was a consequence of oesophageal distension induced by gas reflux rather than a component of the opening mechanism...
  50. ncbi request reprint Comparing lansoprazole and omeprazole in onset of heartburn relief: results of a randomized, controlled trial in erosive esophagitis patients
    J E Richter
    Department of Gastroenterology, The Cleveland Clinic Foundation, Ohio 44195, USA
    Am J Gastroenterol 96:3089-98. 2001
    ..Both treatments were safe and well tolerated. CONCLUSIONS: Over 8 wk, lansoprazole 30 mg once daily relieved heartburn symptoms faster and more effectively than omeprazole 20 mg once daily in patients with erosive esophagitis...
  51. ncbi request reprint Inconsistent association of esophageal symptoms, psychometric abnormalities and dysmotility
    C W Song
    Institute of Digestive Disease and Nutrition and Department of Psychiatry, Medical College of Korea University, Seoul
    Am J Gastroenterol 96:2312-6. 2001
    ..CONCLUSIONS: The esophageal symptoms of patients with abnormal esophageal motility may relate to the underlying psychological abnormalities, independent of manometric abnormalities...
  52. ncbi request reprint Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial
    J E Richter
    Department of Gastroenterology, Cleveland Clinic Foundation, Ohio 44195, USA
    Am J Gastroenterol 96:656-65. 2001
    ..CONCLUSIONS: Esomeprazole demonstrates significantly greater efficacy than omeprazole in the treatment of GERD patients with erosive esophagitis. The tolerability and safety of esomeprazole are comparable to that of omeprazole. (Am..
  53. ncbi request reprint Anatomy, physiology and pathophysiology of dysphagia
    P J Kahrilas
    Department of Medicine, Northwestern University, Chicago, Illinois
    Acta Otorhinolaryngol Belg 48:97-117. 1994
    ..Specific therapy can then be addressed toward correcting dysfunctional elements...