Mark Johnson

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc 'What controls aqueous humour outflow resistance?'
    Mark Johnson
    Department of Biomedical Engineering, Northwestern University, TECH E378, 2145 Sheridan Road, Evanston, IL 60208, USA
    Exp Eye Res 82:545-57. 2006
  2. pmc Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane
    Jiahn Dar Huang
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208 3107, USA
    Invest Ophthalmol Vis Sci 49:2721-7. 2008
  3. pmc Comparison of morphology of human macular and peripheral Bruch's membrane in older eyes
    Mark Johnson
    Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Curr Eye Res 32:791-9. 2007
  4. pmc The hydraulic conductivity of Matrigel
    William J McCarty
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
    Biorheology 44:303-17. 2007
  5. pmc The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium
    Darryl R Overby
    Tulane University, Department of Biomedical Engineering, New Orleans, LA, USA
    Exp Eye Res 88:656-70. 2009
  6. pmc Effects of particulates and lipids on the hydraulic conductivity of Matrigel
    William J McCarty
    Department of Biomedical Engineering, TECH Rm E378, Northwestern University, 2145 Sheridan Rd, Evanston, IL 60208, USA
    J Appl Physiol (1985) 105:621-8. 2008
  7. doi request reprint Young's modulus of elasticity of Schlemm's canal endothelial cells
    Dehong Zeng
    Department of Biomedical Engineering, Northwestern University, Evanston, USA
    Biomech Model Mechanobiol 9:19-33. 2010
  8. pmc Passage of low-density lipoproteins through Bruch's membrane and choroid
    Zdravka Cankova
    Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 3107, USA
    Exp Eye Res 93:947-55. 2011
  9. ncbi request reprint Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane
    Jeffrey W Ruberti
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Invest Ophthalmol Vis Sci 44:1753-9. 2003
  10. pmc Adequacy of exchanging the content of the anterior chamber
    Mark Johnson
    Department of Biomedical Engineering, Northwestern University, TECH E378, 2145 Sheridan Rd, Evanston, IL 60208, United States
    Exp Eye Res 91:876-80. 2010

Collaborators

Detail Information

Publications18

  1. pmc 'What controls aqueous humour outflow resistance?'
    Mark Johnson
    Department of Biomedical Engineering, Northwestern University, TECH E378, 2145 Sheridan Road, Evanston, IL 60208, USA
    Exp Eye Res 82:545-57. 2006
    ....
  2. pmc Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane
    Jiahn Dar Huang
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208 3107, USA
    Invest Ophthalmol Vis Sci 49:2721-7. 2008
    ..To determine the size and regional distribution of lipoprotein-like particles (LLPs) that accumulate with age in Bruch's membrane (BrM)...
  3. pmc Comparison of morphology of human macular and peripheral Bruch's membrane in older eyes
    Mark Johnson
    Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Curr Eye Res 32:791-9. 2007
    ..The "lipid wall," reported in macular BrM, was also found occasionally in the peripheral regions. The same processes that lead to age-related accumulation of LLPs in macular BrM appear to also occur in the peripheral regions...
  4. pmc The hydraulic conductivity of Matrigel
    William J McCarty
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
    Biorheology 44:303-17. 2007
    ..We conclude that K of multi-component gels, such as Matrigel can be well characterized by fiber matrix models, and that pressure-induced changes in K of such gels can be well characterized by biphasic models...
  5. pmc The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium
    Darryl R Overby
    Tulane University, Department of Biomedical Engineering, New Orleans, LA, USA
    Exp Eye Res 88:656-70. 2009
    ..Further study is greatly needed to better characterize these important interactions...
  6. pmc Effects of particulates and lipids on the hydraulic conductivity of Matrigel
    William J McCarty
    Department of Biomedical Engineering, TECH Rm E378, Northwestern University, 2145 Sheridan Rd, Evanston, IL 60208, USA
    J Appl Physiol (1985) 105:621-8. 2008
    ....
  7. doi request reprint Young's modulus of elasticity of Schlemm's canal endothelial cells
    Dehong Zeng
    Department of Biomedical Engineering, Northwestern University, Evanston, USA
    Biomech Model Mechanobiol 9:19-33. 2010
    ..These moduli can be used to estimate the extent to which SC cells deform in response to the pressure drop across the inner wall endothelium and thereby estimate the extent to which they can generate outflow resistance...
  8. pmc Passage of low-density lipoproteins through Bruch's membrane and choroid
    Zdravka Cankova
    Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 3107, USA
    Exp Eye Res 93:947-55. 2011
    ..51 ± 0.33, n = 8). Our data suggested that the DiI-LDL was modestly hindered and/or captured by the tissue. This might explain the progressive decrease of hydraulic conductivity with continued perfusion of DiI-LDL...
  9. ncbi request reprint Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane
    Jeffrey W Ruberti
    Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Invest Ophthalmol Vis Sci 44:1753-9. 2003
    ..To examine age-related changes in the ultrastructure of Bruch's membrane with quick-freeze/deep-etch (QFDE) and conventional thin-section transmission electron microscopy (TEM)...
  10. pmc Adequacy of exchanging the content of the anterior chamber
    Mark Johnson
    Department of Biomedical Engineering, Northwestern University, TECH E378, 2145 Sheridan Rd, Evanston, IL 60208, United States
    Exp Eye Res 91:876-80. 2010
    ..We found that exchange of the anterior chamber to reduce the concentration of a drug or tracer by 20-fold required a perfused volume three times the combined volume of the upstream tubing and anterior chamber...
  11. pmc Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch
    Jiahn Dar Huang
    Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 3107, USA
    Exp Eye Res 85:202-18. 2007
    ....
  12. ncbi request reprint The pore density in the inner wall endothelium of Schlemm's canal of glaucomatous eyes
    Mark Johnson
    Biomedical Engineering Department, Northwestern University, Evanston, Illinois 60208, USA
    Invest Ophthalmol Vis Sci 43:2950-5. 2002
    ..The objective of the current study was to compare the inner wall's pore density in glaucomatous and normal eyes, accounting for the effects of fixation conditions...
  13. ncbi request reprint The mechanism of increasing outflow facility during washout in the bovine eye
    Darryl Overby
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, USA
    Invest Ophthalmol Vis Sci 43:3455-64. 2002
    ..To investigate the relationship between outflow facility and separation between the inner wall of the aqueous plexus and the juxtacanalicular connective tissue (JCT) during washout in the bovine eye...
  14. ncbi request reprint A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy
    Haiyan Gong
    Boston University School of Medicine, Boston, MA 02118, USA
    Exp Eye Res 75:347-58. 2002
    ....
  15. ncbi request reprint Glaucoma surgery and aqueous outflow: how does nonpenetrating glaucoma surgery work?
    Douglas H Johnson
    Arch Ophthalmol 120:67-70. 2002
  16. ncbi request reprint Studies on depth-of-field effects in microscopy supported by numerical simulations
    Darryl R Overby
    Department of Mechanical Engineering, MIT, Cambridge, MA, USA
    J Microsc 220:176-89. 2005
    ..Applications of the stereological theory towards analysis of biological tissues and extracellular matrix are discussed...
  17. ncbi request reprint Ocular biomechanics and biotransport
    C Ross Ethier
    Department of Mechanical and Industrial Engineering, and Institute for Biomaterials and Biomedical Engineering, University of Toronto, Ontario, M5S 3G8, Canada
    Annu Rev Biomed Eng 6:249-73. 2004
    ..In this review, we give a (necessarily brief) overview of many of the interesting biomechanical aspects of the eye, concluding with a list of open problems...
  18. ncbi request reprint A principled method for determining the functionality of brain responses
    Philippe G Schyns
    Department of Psychology, University of Glasgow, 58 Hillhead Street, Glasgow G12 8QB, Scotland, UK
    Neuroreport 14:1665-9. 2003
    ..This suggests a new methodology to attribute function to different components of the neural system for perceiving complex stimuli...