Michael C Jewett

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation
    Michael C Jewett
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Mol Syst Biol 9:678. 2013
  2. pmc Update on designing and building minimal cells
    Michael C Jewett
    Department of Chemical and Biological Engineering and Chemistry of Life Processes Institute, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Curr Opin Biotechnol 21:697-703. 2010
  3. doi request reprint Optimized extract preparation methods and reaction conditions for improved yeast cell-free protein synthesis
    C Eric Hodgman
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Biotechnol Bioeng 110:2643-54. 2013
  4. pmc Biology by design: from top to bottom and back
    Brian R Fritz
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    J Biomed Biotechnol 2010:232016. 2010
  5. doi request reprint Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
    Farren J Isaacs
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 333:348-53. 2011
  6. doi request reprint Cell-free protein synthesis: applications come of age
    Erik D Carlson
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Biotechnol Adv 30:1185-94. 2012
  7. doi request reprint Cell-free biology: exploiting the interface between synthetic biology and synthetic chemistry
    D Calvin Harris
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Curr Opin Biotechnol 23:672-8. 2012
  8. pmc Synthetic in vitro circuits
    Adam J Hockenberry
    Interdepartmental Biological Sciences Graduate Program, Northwestern University, Evanston, IL 60208, USA
    Curr Opin Chem Biol 16:253-9. 2012

Collaborators

Detail Information

Publications8

  1. doi request reprint In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation
    Michael C Jewett
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Mol Syst Biol 9:678. 2013
    ..We anticipate that iSAT will aid studies of ribosome assembly and open new avenues for making ribosomes with altered properties. ..
  2. pmc Update on designing and building minimal cells
    Michael C Jewett
    Department of Chemical and Biological Engineering and Chemistry of Life Processes Institute, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Curr Opin Biotechnol 21:697-703. 2010
    ..Major progress in the past 5 years has occurred in synthetic genomics, minimization of the Escherichia coli genome, sequencing of minimal bacterial endosymbionts, identification of essential genes, and integration of biochemical systems...
  3. doi request reprint Optimized extract preparation methods and reaction conditions for improved yeast cell-free protein synthesis
    C Eric Hodgman
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Biotechnol Bioeng 110:2643-54. 2013
    ..Our results set the stage for developing a yeast CFPS platform that provides for high-yielding and cost-effective expression of a variety of protein therapeutics and protein libraries...
  4. pmc Biology by design: from top to bottom and back
    Brian R Fritz
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    J Biomed Biotechnol 2010:232016. 2010
    ..Ten years after the construction of synthetic biology's first devices, the drive to look beyond what does exist to what can exist is ushering in an era of biology by design...
  5. doi request reprint Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
    Farren J Isaacs
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 333:348-53. 2011
    ..Our methods treat the chromosome as both an editable and an evolvable template, permitting the exploration of vast genetic landscapes...
  6. doi request reprint Cell-free protein synthesis: applications come of age
    Erik D Carlson
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Biotechnol Adv 30:1185-94. 2012
    ..In the coming years, cell-free protein synthesis promises new industrial processes where short protein production timelines are crucial as well as innovative approaches to a wide range of applications...
  7. doi request reprint Cell-free biology: exploiting the interface between synthetic biology and synthetic chemistry
    D Calvin Harris
    Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA
    Curr Opin Biotechnol 23:672-8. 2012
    ..In the coming years, the impact of advances inspired by these approaches will make possible the synthesis of nonbiological polymers having new backbone compositions, new chemical properties, new structures, and new functions...
  8. pmc Synthetic in vitro circuits
    Adam J Hockenberry
    Interdepartmental Biological Sciences Graduate Program, Northwestern University, Evanston, IL 60208, USA
    Curr Opin Chem Biol 16:253-9. 2012
    ..Progress in this field is showing that cell-free synthetic biology is a versatile testing ground for understanding native biological circuits and engineering novel functionality...