Research Topics
| Agnella D IzzoSummaryAffiliation: Northwestern University Country: USA Publications
Research Grants
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Detail Information
Publications
Laser stimulation of the auditory nerveAgnella D Izzo
Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA
Lasers Surg Med 38:745-53. 2006..CONCLUSIONS: We have demonstrated that the auditory nerve can be stimulated by optical radiation. One potential clinical use of this technology would be for cochlear implants...
Spatial extent of cochlear infrared neural stimulation determined by tone-on-light maskingAgnella Izzo Matic
Northwestern University, Feinberg School of Medicine, Department of Otolaryngology, Chicago, Illinois 60611, USA
J Biomed Opt 16:118002. 2011..The results indicate that the spatial area of INS in the gerbil cochlea is similar to the cochlear area excited by a low level acoustic tone, showing promising results for future use of INS in implantable cochlear prostheses...
Light-induced modulation of Porphyromonas gingivalis growthAgnella D Izzo
Biomedical Engineering Department, Northwestern University, Evanston, IL 60208, USA
J Photochem Photobiol B 77:63-9. 2004..These results indicate that heat-induced killing of P. gingivalis could be the mechanism behind successful irradiation experiments with this bacterium...
Optical parameter variability in laser nerve stimulation: a study of pulse duration, repetition rate, and wavelengthAgnella D Izzo
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA
IEEE Trans Biomed Eng 54:1108-14. 2007..The technology of optical stimulation could significantly improve cochlear implants, which are hampered by a lack of spatial selectivity...
Laser stimulation of auditory neurons: effect of shorter pulse duration and penetration depthAgnella D Izzo
Department of Otolaryngology, Northwestern University, Chicago, Illinois 60611, USA
Biophys J 94:3159-66. 2008..The implications of these data could direct further research and design of an optical cochlear implant...
Selectivity of neural stimulation in the auditory system: a comparison of optic and electric stimuliAgnella D Izzo
Northwestern University, Biomedical Engineering, 2145 Sheridan Road, Tech E310, Evanston, Illinois 60208, USA
J Biomed Opt 12:021008. 2007..In the auditory system, optical stimulation of nerves could have a significant impact on the performance of cochlear implants, which can be limited by the electric current spread...
Optical stimulation of auditory neurons: effects of acute and chronic deafeningClaus Peter Richter
Department of Otolaryngology, Northwestern University, 303 E Chicago Avenue, Searle 12 561, Chicago, IL 60611, USA
Hear Res 242:42-51. 2008..However, in chronically deaf animals optically evoked CAP thresholds were elevated. Changes correlated with the number of surviving spiral ganglion cells and the optical parameters that were used for stimulation...
Optical stimulation of the facial nerve: a new monitoring technique?Ingo Ulrik Teudt
Department of Otolaryngology Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611 3008, USA
Laryngoscope 117:1641-7. 2007..In contrast to electrical stimulation, pulsed infrared optical radiation can be used to safely and selectively stimulate neural tissue and might be valuable for screening...
Research Grants
- Optical stimulation of the auditory nerveAGNELLA IZZO; Fiscal Year: 2006..Aim (2) will utilize the variable-wavelength, variable-repetition rate Free Electron Laser to demonstrate optical stimulation of auditory neurons at high repetition rates. ..
