M G Ison

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint Clinical use of approved influenza antivirals: therapy and prophylaxis
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL 60654, USA
    Influenza Other Respi Viruses 7:7-13. 2013
  2. pmc Preventable errors in organ transplantation: an emerging patient safety issue?
    M G Ison
    Divisions of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Am J Transplant 12:2307-12. 2012
  3. doi request reprint Efficacy and safety of oral oseltamivir for influenza prophylaxis in transplant recipients
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Antivir Ther 17:955-64. 2012
  4. doi request reprint Antivirals and resistance: influenza virus
    Michael G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States
    Curr Opin Virol 1:563-73. 2011
  5. doi request reprint Antiviral therapies for respiratory viral infections in lung transplant patients
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Antivir Ther 17:193-200. 2012
  6. ncbi request reprint Epidemiology, prevention, and management of influenza in patients with hematologic malignancy
    Michael G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Infect Disord Drug Targets 11:34-9. 2011
  7. doi request reprint Influenza 2010-2011: lessons from the 2009 pandemic
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Departments of Medicine and Surgery, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue Suite 900, Chicago, IL 60611, USA
    Cleve Clin J Med 77:812-20. 2010
  8. doi request reprint Influenza, including the novel H1N1, in organ transplant patients
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA
    Curr Opin Infect Dis 23:365-73. 2010
  9. doi request reprint End points for testing influenza antiviral treatments for patients at high risk of severe and life-threatening disease
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Infect Dis 201:1654-62. 2010
  10. doi request reprint Transplantation of high-risk donor organs: a survey of US solid organ transplant center practices as reported by transplant infectious diseases physicians
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Clin Transplant 23:866-73. 2009

Collaborators

Detail Information

Publications47

  1. doi request reprint Clinical use of approved influenza antivirals: therapy and prophylaxis
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL 60654, USA
    Influenza Other Respi Viruses 7:7-13. 2013
    ..This article reviews the pharmacokinetics and clinical data available relative to the use of commercially available antiviral agents for the prevention of and treatment for influenza...
  2. pmc Preventable errors in organ transplantation: an emerging patient safety issue?
    M G Ison
    Divisions of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Am J Transplant 12:2307-12. 2012
    ..Further, the transplant community needs to embrace the implementation of evidence-based system and process improvements that will mitigate existing safety vulnerabilities...
  3. doi request reprint Efficacy and safety of oral oseltamivir for influenza prophylaxis in transplant recipients
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Antivir Ther 17:955-64. 2012
    ..Haematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT) recipients are at high risk for severe influenza and its complications, and may not be adequately protected by vaccination...
  4. doi request reprint Antivirals and resistance: influenza virus
    Michael G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States
    Curr Opin Virol 1:563-73. 2011
    ..In this paper, we will review the currently approved and investigational antiviral agents and the mechanisms of resistance that impact their activity...
  5. doi request reprint Antiviral therapies for respiratory viral infections in lung transplant patients
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Antivir Ther 17:193-200. 2012
    ..This paper will review the epidemiology and management strategies of respiratory viral infections in lung transplant recipients...
  6. ncbi request reprint Epidemiology, prevention, and management of influenza in patients with hematologic malignancy
    Michael G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Infect Disord Drug Targets 11:34-9. 2011
    ..Available evidence suggests that prolonged course are frequently needed. Patients who fail to response or have relapsed infections should be tested for emergence of antiviral resistance and alternative diagnoses should be investigated...
  7. doi request reprint Influenza 2010-2011: lessons from the 2009 pandemic
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Departments of Medicine and Surgery, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue Suite 900, Chicago, IL 60611, USA
    Cleve Clin J Med 77:812-20. 2010
    ..Much was learned about the diagnosis, management, and pathogenesis of influenza from the 2009 pandemic of influenza A (H1N1). This knowledge can be applied to the management of people affected by seasonal infection and to future pandemics...
  8. doi request reprint Influenza, including the novel H1N1, in organ transplant patients
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA
    Curr Opin Infect Dis 23:365-73. 2010
    ..This article will review the epidemiology, diagnosis, prevention and management of influenza in solid organ transplant recipients...
  9. doi request reprint End points for testing influenza antiviral treatments for patients at high risk of severe and life-threatening disease
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Infect Dis 201:1654-62. 2010
    ....
  10. doi request reprint Transplantation of high-risk donor organs: a survey of US solid organ transplant center practices as reported by transplant infectious diseases physicians
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Clin Transplant 23:866-73. 2009
    ..There is significant variability in the acceptance and management of ROHRD in the US. Most TID experts do not feel that the current PHS guidelines accurately define high-risk donors...
  11. doi request reprint Respiratory syncytial virus and other respiratory viruses in the setting of bone marrow transplantation
    Michael G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Curr Opin Oncol 21:171-6. 2009
    ..Several epidemiologic studies have enhanced our understanding of the impact of respiratory viruses on bone marrow transplant recipients...
  12. doi request reprint Donor-derived disease transmission events in the United States: data reviewed by the OPTN/UNOS Disease Transmission Advisory Committee
    M G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Transplant 9:1929-35. 2009
    ..96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the transmission risk of infection and malignancy through organ transplantation...
  13. doi request reprint The epidemiology and prevention of donor-derived infections
    Michael G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Adv Chronic Kidney Dis 16:234-41. 2009
    ..The regulatory framework related to and the epidemiology, identification, and management of donor-derived infectious disease transmission shall be reviewed...
  14. doi request reprint Outcome of influenza infection managed with oseltamivir in lung transplant recipients
    Michael G Ison
    Division of Infectious Diseases and Organ Transplantation, Transplant and Immunocompromised Host Infectious Diseases Service, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Heart Lung Transplant 27:282-8. 2008
    ....
  15. doi request reprint An update on donor-derived disease transmission in organ transplantation
    M G Ison
    Divisions of Infectious Diseases and Organ Transplantation, Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Am J Transplant 11:1123-30. 2011
    ..As the epidemiology of donor-derived disease transmission has become better understood, several groups have been working on methods to further mitigate this risk...
  16. ncbi request reprint Respiratory viral infections in transplant recipients
    Michael G Ison
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Antivir Ther 12:627-38. 2007
    ..In addition to epidemiological data, recent studies have also advanced our understanding of management of influenza, adenovirus, and RSV infections among transplant recipients...
  17. doi request reprint Screening and treatment of chagas disease in organ transplant recipients in the United States: recommendations from the chagas in transplant working group
    P V Chin-Hong
    Division of Infectious Diseases, University of California, San Francisco, San Francisco, CA, USA
    Am J Transplant 11:672-80. 2011
    ..Data on management and outcomes of all cases should be collected to inform future guidelines and to assist in coordination with public health authorities...
  18. doi request reprint Diagnosis and management of tuberculosis in transplant donors: a donor-derived infections consensus conference report
    M I Morris
    Division of Infectious Diseases, University of Miami Miller School of Medicine, FL, USA
    Am J Transplant 12:2288-300. 2012
    ..This working group reviewed the currently available data to formulate consensus recommendations for screening and management of TB in organ donors...
  19. doi request reprint Use of the QuantiFERON-TB Gold interferon-gamma release assay for screening transplant candidates: a single-center retrospective study
    N Theodoropoulos
    Division of Infectious Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Transpl Infect Dis 14:1-8. 2012
    ....
  20. doi request reprint Organ donor screening practices for Trypanosoma cruzi infection among US Organ Procurement Organizations
    B S Schwartz
    Division of Infectious Diseases, University of California, San Francisco, San Francisco, CA, USA
    Am J Transplant 11:848-51. 2011
    ..Further research is needed to identify the risk of donor-derived T. cruzi infections to help inform the best screening strategy...
  21. doi request reprint BK virus replication and nephropathy after alemtuzumab-induced kidney transplantation
    N Theodoropoulos
    Division of Infectious Diseases, The Ohio State University College of Medicine, Columbus, USA
    Am J Transplant 13:197-206. 2013
    ..The incidence of BK viruria, viremia and nephropathy was not significantly different among kidney transplant recipients who received alemtuzumab induction compared to patients receiving less potent induction...
  22. ncbi request reprint Therapeutic options for the management of influenza
    M G Ison
    University of Virginia Health Sciences Center, Division of Infectious Diseases, Charlottesville 22908, USA
    Curr Opin Pharmacol 1:482-90. 2001
    ..Studies are also needed to address other groups at increased risk for influenza complications, such as pregnant women and children below one year of age...
  23. doi request reprint Opportunities for shared decision making in kidney transplantation
    E J Gordon
    Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Transplant 13:1149-58. 2013
    ..We propose strategies to promote and overcome obstacles to SDM in kidney transplantation. We contend that engagement in SDM can be facilitated by re-organization of clinical care, communication and education of providers and patients...
  24. doi request reprint Transmission of human immunodeficiency virus and hepatitis C virus from an organ donor to four transplant recipients
    M G Ison
    Division of Infectious Diseases Division of Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Transplant 11:1218-25. 2011
    ..Routine posttransplant HIV and HCV serological testing and NAT of recipients of organs from donors with suspected risk factors should be considered as routine practice...
  25. doi request reprint Carbapenem-resistant Acinetobacter baumannii infections after organ transplantation
    P Reddy
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Transpl Infect Dis 12:87-93. 2010
    ..The current study suggests that SOT patients with CRAB suffer from prolonged hospitalization, infection with other MDR organisms, allograft dysfunction and loss, and high overall infection-related mortality...
  26. pmc Detection and diagnosis of herpes simplex virus infection in adults with acute liver failure
    Josh Levitsky
    Northwestern Memorial Hospital Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Liver Transpl 14:1498-504. 2008
    ....
  27. doi request reprint Alemtuzumab induction in non-hepatitis C positive liver transplant recipients
    Josh Levitsky
    Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Liver Transpl 17:32-7. 2011
    ..In conclusion, a steroid-free AL induction regimen was associated with less hypertension and rejection but with more infectious complications; thus, the overall benefit of AL induction in LT recipients is called into question...
  28. ncbi request reprint Viral infections in immunocompromised patients: what's new with respiratory viruses?
    Michael G Ison
    Division of Infectious Diseases, University of Virginia, Charlottesville, Virginia 22908, USA
    Curr Opin Infect Dis 15:355-67. 2002
    ..The respiratory viruses, particularly respiratory syncytial virus, influenza, parainfluenza, adenovirus, and picornaviruses, are increasingly recognized as significant pathogens in these populations...
  29. doi request reprint Expanded infectious diseases screening program for Hispanic transplant candidates
    M A Fitzpatrick
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Transpl Infect Dis 12:336-41. 2010
    ..Expanded screening identifies endemic infections in the Hispanic immigrant population that can be treated before transplant, thereby minimizing post-transplant infectious complications...
  30. doi request reprint Deceased Organ Donor Screening for HIV, Hepatitis B, and Hepatitis C Viruses: A Survey of Organ Procurement Organization Practices
    N Theodoropoulos
    Division of Infectious Diseases, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH Northwestern University Transplant Outcomes Research Collaborative, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL
    Am J Transplant 13:2186-90. 2013
    ..Since 2008, the number of OPOs performing NAT has increased and more OPOs are testing all donors. ..
  31. doi request reprint The challenge of informed consent for increased risk living donation and transplantation
    E J Gordon
    Institute for Healthcare Studies, Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Am J Transplant 11:2569-74. 2011
    ..Optimizing a recipient's informed consent is essential to protecting patient safety and autonomy...
  32. doi request reprint Infections transmitted by transplantation
    Michele I Morris
    Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL, USA
    Infect Dis Clin North Am 24:497-514. 2010
    ..Issues related to the epidemiology of, screening for, and management of proven or probable donor-derived infections are reviewed in this article...
  33. ncbi request reprint Prevention and early treatment of opportunistic viral infections in patients with leukemia and allogeneic stem cell transplantation recipients
    Michael Angarone
    Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    J Natl Compr Canc Netw 6:191-201. 2008
    ..Fortunately, a growing armamentarium is allowing more effective prophylaxis of these pathogens. This article reviews the epidemiology and prophylactic strategies available for these common opportunistic viral pathogens...
  34. doi request reprint Donor screening for human T-cell lymphotrophic virus 1/2: changing paradigms for changing testing capacity
    D R Kaul
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Transplant 10:207-13. 2010
    ....
  35. ncbi request reprint A survey of CMV prevention strategies after liver transplantation
    J Levitsky
    Department of Medicine, Division of Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Am J Transplant 8:158-61. 2008
    ..In conclusion, the majority of LT centers utilize CMV prophylaxis over other strategies. Valganciclovir is the most commonly used agent for both antiviral prophylaxis and treatment of CMV viremia in the preemptive approach...
  36. ncbi request reprint Fatal adenovirus pneumonia in a person with AIDS and Burkitt lymphoma: a case report and review of the literature
    Oluwadamilola A Adeyemi
    Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    AIDS Read 18:196-8, 201-2, 206-7. 2008
    ....
  37. ncbi request reprint Adenovirus infections in transplant recipients
    Michael G Ison
    Division of Infectious Diseases, Transplant Infectious Diseases Service, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Clin Infect Dis 43:331-9. 2006
    ..Prospective studies are needed to better understand the pathogenesis of and therapeutic options for adenoviral infections in this patient population...
  38. doi request reprint Development of BK nephropathy in recipients of simultaneous pancreas-kidney transplantation
    Michael G Ison
    Division of Infectious Disease, Department of Medicine, Feinberg School of Medicine, Northwestern University Chicago, Chicago, IL, USA
    Transplantation 87:525-30. 2009
    ..The presence of dual organs limits the ability to reduce maintenance immunosuppression, typically the first intervention in the management of BKVN...
  39. ncbi request reprint Current research on respiratory viral infections: Fourth International Symposium
    Michael G Ison
    University of Virginia School of Medicine, Charlottesville, VA, USA
    Antiviral Res 55:227-78. 2002
  40. ncbi request reprint Rhinovirus infections in hematopoietic stem cell transplant recipients with pneumonia
    Michael G Ison
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA
    Clin Infect Dis 36:1139-43. 2003
    ..Whether the poor prognosis is due to HRV or the copathogen is not clear...
  41. ncbi request reprint Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza
    Michael G Ison
    University of Virginia, Charlottesville, VA, USA
    Antivir Ther 8:183-90. 2003
    ..Two rimantadine-resistant viruses emerged during rimantadine monotherapy; no ZNV resistance was observed. Nebulized ZNV appears to be well tolerated in this hospitalized population but further studies are needed to assess its efficacy...
  42. ncbi request reprint Prevention and treatment of cancer-related infections
    Brahm H Segal
    Roswell Park Cancer Institute, USA
    J Natl Compr Canc Netw 6:122-74. 2008
  43. ncbi request reprint Cardiac findings during uncomplicated acute influenza in ambulatory adults
    Michael G Ison
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, USA
    Clin Infect Dis 40:415-22. 2005
    ..Previous studies have reported abnormal cardiac findings in up to 43% of ambulatory adults with influenza. This study was conducted to determine the frequency, magnitude, and duration of myocardial dysfunction in such persons...
  44. ncbi request reprint Cytomegalovirus pneumonia in transplant recipients
    Michael G Ison
    Transplant Infectious Disease and Compromised Host Program, Infectious Disease Division, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Chest Med 26:691-705, viii. 2005
    ..Invasive procedures are often required for the optimal management of such infections. The use of sensitive and quantitative assays have greatly improved the outcomes of CMV infection...
  45. ncbi request reprint Recovery of drug-resistant influenza virus from immunocompromised patients: a case series
    Michael G Ison
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health Sciences Center, Charlottesville, 22908, USA
    J Infect Dis 193:760-4. 2006
    ..We describe a novel Asp198Asn NA mutation in an influenza B virus and its decreased susceptibility to both oseltamivir and zanamivir...
  46. ncbi request reprint Comparative activities of oseltamivir and A-322278 in immunocompetent and immunocompromised murine models of influenza virus infection
    Michael G Ison
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health Sciences Center, Charlottesville, 22908, USA
    J Infect Dis 193:765-72. 2006
    ..This model would be useful for elucidation of the molecular mechanisms of resistance to NA inhibitors and for testing of anti-influenza therapy options that might prevent the emergence of resistant variants...
  47. ncbi request reprint Current research on respiratory viral infections: Fifth International Symposium
    Michael G Ison
    University of Virginia School of Medicine, Charlottesville, USA
    Antiviral Res 62:75-110. 2004