K A Horvath

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi Thoracoscopic transmyocardial laser revascularization
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 65:1439-41. 1998
  2. ncbi Mechanisms and results of transmyocardial laser revascularization
    Keith A Horvath
    Northwestern University, Chicago, IL 60611, USA
    Cardiology 101:37-47. 2004
  3. ncbi Myocardial functional recovery after fibroblast growth factor 2 gene therapy as assessed by echocardiography and magnetic resonance imaging
    Keith A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 74:481-6; discussion 487. 2002
  4. ncbi Transmyocardial laser revascularization
    Keith A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 73:1355-6. 2002
  5. ncbi Results of prospective randomized controlled trials of transmyocardial laser revascularization
    Keith A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Heart Surg Forum 5:33-9; discussion 39-40. 2002
  6. ncbi Functional comparison of transmyocardial revascularization by mechanical and laser means
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 72:1997-2002. 2001
  7. ncbi Transmyocardial laser revascularization in the treatment of myocardial ischemia
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Card Surg 15:271-7. 2000
  8. ncbi Results of clinical trials of transmyocardial laser revascularization versus medical management for end-stage coronary disease
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Clin Laser Med Surg 18:247-52. 2000
  9. ncbi Sustained angina relief 5 years after transmyocardial laser revascularization with a CO(2) laser
    K A Horvath
    Northwestern University Medical School, Chicago, Illinois, USA
    Circulation 104:I81-4. 2001
  10. ncbi Up-regulation of vascular endothelial growth factor mRNA and angiogenesis after transmyocardial laser revascularization
    K A Horvath
    Feinberg Cardiovascular Research Institute, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 68:825-9. 1999

Collaborators

Detail Information

Publications26

  1. ncbi Thoracoscopic transmyocardial laser revascularization
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 65:1439-41. 1998
    ..Typically, the operative approach is through a left anterior thoracotomy. I report a case of transmyocardial laser revascularization performed thoracoscopically...
  2. ncbi Mechanisms and results of transmyocardial laser revascularization
    Keith A Horvath
    Northwestern University, Chicago, IL 60611, USA
    Cardiology 101:37-47. 2004
    ..The results of using TMR as a treatment for angina show a dramatic improvement in symptoms and quality of life. This paper reviews the current status of TMR techniques, mechanisms and results...
  3. ncbi Myocardial functional recovery after fibroblast growth factor 2 gene therapy as assessed by echocardiography and magnetic resonance imaging
    Keith A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 74:481-6; discussion 487. 2002
    ....
  4. ncbi Transmyocardial laser revascularization
    Keith A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 73:1355-6. 2002
  5. ncbi Results of prospective randomized controlled trials of transmyocardial laser revascularization
    Keith A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Heart Surg Forum 5:33-9; discussion 39-40. 2002
    ..While all of these trials are similar, they are not identical and this review provides an update and comparison of the results...
  6. ncbi Functional comparison of transmyocardial revascularization by mechanical and laser means
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 72:1997-2002. 2001
    ..The purpose of this study was to determine whether mechanical TMR improves ventricular function as compared with laser TMR in chronically ischemic myocardium...
  7. ncbi Transmyocardial laser revascularization in the treatment of myocardial ischemia
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Card Surg 15:271-7. 2000
    ..Although the trials are similar, they are not identical, and this review provides an update and comparison of their results...
  8. ncbi Results of clinical trials of transmyocardial laser revascularization versus medical management for end-stage coronary disease
    K A Horvath
    Division of Cardiothoracic Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Clin Laser Med Surg 18:247-52. 2000
    ..Recently, four prospective randomized controlled clinical trials have reported their results in comparing TMR to maximal medical therapy. The purpose of this review is to provide an update and comparison of the results of these trials...
  9. ncbi Sustained angina relief 5 years after transmyocardial laser revascularization with a CO(2) laser
    K A Horvath
    Northwestern University Medical School, Chicago, Illinois, USA
    Circulation 104:I81-4. 2001
    ..Angina symptoms as assessed independently by angina class and the Seattle Angina Questionnaire (SAQ) were prospectively collected up to 7 years after TMR...
  10. ncbi Up-regulation of vascular endothelial growth factor mRNA and angiogenesis after transmyocardial laser revascularization
    K A Horvath
    Feinberg Cardiovascular Research Institute, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 68:825-9. 1999
    ..The purpose of this study was to demonstrate that the molecular response to TMLR was an increase in the production of endogenous vascular endothelial growth factor to promote angiogenesis...
  11. ncbi Left ventricular functional improvement after transmyocardial laser revascularization
    K A Horvath
    Feinberg Cardiovascular Research Institute, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Ann Thorac Surg 66:721-5. 1998
    ..The purpose of this study was to determine whether transmyocardial laser revascularization improves myocardial function in chronically ischemic myocardium...
  12. ncbi Improvement of myocardial contractility in a porcine model of chronic ischemia using a combined transmyocardial revascularization and gene therapy approach
    Keith A Horvath
    Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    J Thorac Cardiovasc Surg 129:1071-7. 2005
    ....
  13. ncbi The Ross procedure in adults: intermediate-term results
    David A Fullerton
    Division of Cardiothoracic Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Ann Thorac Surg 76:471-6; discussion 476-7. 2003
    ..We employed a surgical strategy to standardize the operation in order to avoid more readily a geometric mismatch...
  14. ncbi The Society of Thoracic Surgeons practice guideline series: transmyocardial laser revascularization
    Charles R Bridges
    Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 77:1494-502. 2004
    ....
  15. ncbi What is the optimal channel density for transmyocardial laser revascularization?
    Samdeep K Mouli
    Division of Cardiothoracic Surgery, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Ann Thorac Surg 78:1326-31; discussion 1326-31. 2004
    ..Transmyocardial laser revascularization (TMR) has demonstrated reproducible relief of angina in patients with end-stage coronary disease. However, the optimum dose or channel density has not been elucidated...
  16. ncbi Emboli capture using the Embol-X intraaortic filter in cardiac surgery: a multicentered randomized trial of 1,289 patients
    Michael K Banbury
    The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 76:508-15; discussion 515. 2003
    ..Particulate emboli are thought to play a significant role in the development of cardiac surgical complications. Intraaortic filtration of particulate emboli may reduce the burden of this morbidity in cardiac patients...
  17. ncbi Percutaneous laser revascularization does not equal transmyocardial laser revascularization
    Keith A Horvath
    J Am Coll Cardiol 48:2354; author reply 2355. 2006
  18. ncbi Clinical results of sole therapy TMR treatment
    Keith A Horvath
    Cardiothoracic Surgery Research Program, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    Semin Thorac Cardiovasc Surg 18:46-51. 2006
    ..In addition to significant symptomatic relief both short- and long-term objective data were also garnered in these studies. A review of the history, study design, and outcomes is provided...
  19. ncbi Impact of unstable angina on outcomes of transmyocardial laser revascularization combined with coronary artery bypass grafting
    Keith A Horvath
    National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Ann Thorac Surg 80:2082-5. 2005
    ..The objective of this study was to investigate the preoperative risk profile of patients undergoing TMR plus coronary artery bypass graft surgery (CABG) and to determine the impact of unstable angina on outcomes...
  20. pmc Transmyocardial laser revascularization
    Keith A Horvath
    Cardiothoracic Surgery Research, National Heart, Lung and Blood Institute NIH, Bethesda, Maryland 20892, USA
    J Card Surg 23:266-76. 2008
    ..Additional therapies to enhance the angiogenic response include combining TMR with stem cell-based treatments, which appear to be promising future endeavors...
  21. ncbi The incidence of emboli during cardiac surgery: a histopathologic analysis of 2297 patients
    Keith A Horvath
    National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA
    Heart Surg Forum 8:E161-6. 2005
    ..Recently, as a result of worldwide trials deploying the Embol-X intraaortic filter during cardiac surgery, such emboli were captured and processed for histopathologic analysis...
  22. ncbi Light and ice cream
    Keith A Horvath
    Ann Thorac Surg 82:771; author reply 771-2. 2006
  23. pmc Real-time interactive MRI-guided cardiac surgery: aortic valve replacement using a direct apical approach
    Elliot R McVeigh
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1061, USA
    Magn Reson Med 56:958-64. 2006
    ..MRI-guided beating-heart surgery may provide patients with a less morbid and more durable solution to structural heart disease...
  24. ncbi The art and science of transmyocardial laser revascularization
    Keith A Horvath
    J Am Coll Cardiol 41:2298; author reply 2298-9. 2003
  25. ncbi Characterization and expansion of baboon CD4+CD25+ Treg cells for potential use in a non-human primate xenotransplantation model
    Cynthia M Porter
    Division of Cellular and Gene Therapy, CBER, FDA, Bethesda, Mayland 20892, USA
    Xenotransplantation 14:298-308. 2007
    ..Baboons are a preferred preclinical animal model for xenogeneic organ transplantation experiments, and the characterization of baboon Treg cells will be beneficial to future tolerance studies in this animal model...
  26. pmc The visceral pericardium: macromolecular structure and contribution to passive mechanical properties of the left ventricle
    Paul D Jobsis
    National Heart, Lung, and Blood Institute, National Institutes of Health, MSC 1061, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Am J Physiol Heart Circ Physiol 293:H3379-87. 2007
    ..Alterations in this layer may occur in various disease states that effect diastolic function...