Amanda S Hakemian

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi The biochemistry of methane oxidation
    Amanda S Hakemian
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    Annu Rev Biochem 76:223-41. 2007
  2. pmc The metal centers of particulate methane monooxygenase from Methylosinus trichosporium OB3b
    Amanda S Hakemian
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    Biochemistry 47:6793-801. 2008
  3. pmc Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy
    Raquel L Lieberman
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    Inorg Chem 45:8372-81. 2006
  4. pmc The copper chelator methanobactin from Methylosinus trichosporium OB3b binds copper(I)
    Amanda S Hakemian
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    J Am Chem Soc 127:17142-3. 2005
  5. ncbi Mechanism of two-electron oxidation of deoxyguanosine 5'-monophosphate by a platinum(IV) complex
    Sunhee Choi
    Department of Chemistry and Biochemistry, Middlebury College, Middlebury, Vermont 05753, USA
    J Am Chem Soc 126:591-8. 2004

Detail Information

Publications5

  1. ncbi The biochemistry of methane oxidation
    Amanda S Hakemian
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    Annu Rev Biochem 76:223-41. 2007
    ..Finally, methanobactin (mb), a small copper chelator proposed to facilitate copper uptake, has been characterized...
  2. pmc The metal centers of particulate methane monooxygenase from Methylosinus trichosporium OB3b
    Amanda S Hakemian
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    Biochemistry 47:6793-801. 2008
    ..trichosporium OB3b pMMO. These findings extend previous work on pMMO from M. capsulatus (Bath) and provide new insight into the functional importance of the different metal centers...
  3. pmc Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy
    Raquel L Lieberman
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    Inorg Chem 45:8372-81. 2006
    ..These findings are complementary to the crystallographic data and provide new insight into the oxidation states and possible electronic structures of the pMMO Cu ions...
  4. pmc The copper chelator methanobactin from Methylosinus trichosporium OB3b binds copper(I)
    Amanda S Hakemian
    Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
    J Am Chem Soc 127:17142-3. 2005
    ..These results establish definitively that M. trichosporium OB3b methanobactin binds Cu(I) and suggest that methanobactin itself reduces Cu(II) to Cu(I)...
  5. ncbi Mechanism of two-electron oxidation of deoxyguanosine 5'-monophosphate by a platinum(IV) complex
    Sunhee Choi
    Department of Chemistry and Biochemistry, Middlebury College, Middlebury, Vermont 05753, USA
    J Am Chem Soc 126:591-8. 2004
    ..The next step is an inner-sphere, two-electron transfer to produce a cyclic phosphodiester intermediate, 8-hydroxyguanosine cyclic 5',8-(hydrogen phosphate). This intermediate slowly converts to 8-oxo-dGMP by reacting with solvent H(2)O...