Research Topics
| Amanda S HakemianSummaryAffiliation: Northwestern University Country: USA Publications
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Detail Information
Publications
The biochemistry of methane oxidationAmanda S Hakemian
Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
Annu Rev Biochem 76:223-41. 2007..Finally, methanobactin (mb), a small copper chelator proposed to facilitate copper uptake, has been characterized...
The metal centers of particulate methane monooxygenase from Methylosinus trichosporium OB3bAmanda S Hakemian
Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
Biochemistry 47:6793-801. 2008..trichosporium OB3b pMMO. These findings extend previous work on pMMO from M. capsulatus (Bath) and provide new insight into the functional importance of the different metal centers...
Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopyRaquel L Lieberman
Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
Inorg Chem 45:8372-81. 2006..These findings are complementary to the crystallographic data and provide new insight into the oxidation states and possible electronic structures of the pMMO Cu ions...
The copper chelator methanobactin from Methylosinus trichosporium OB3b binds copper(I)Amanda S Hakemian
Department of Biochemistry, Northwestern University, Evanston, Illinois 60208, USA
J Am Chem Soc 127:17142-3. 2005..These results establish definitively that M. trichosporium OB3b methanobactin binds Cu(I) and suggest that methanobactin itself reduces Cu(II) to Cu(I)...
Mechanism of two-electron oxidation of deoxyguanosine 5'-monophosphate by a platinum(IV) complexSunhee Choi
Department of Chemistry and Biochemistry, Middlebury College, Middlebury, Vermont 05753, USA
J Am Chem Soc 126:591-8. 2004..The next step is an inner-sphere, two-electron transfer to produce a cyclic phosphodiester intermediate, 8-hydroxyguanosine cyclic 5',8-(hydrogen phosphate). This intermediate slowly converts to 8-oxo-dGMP by reacting with solvent H(2)O...
