Affiliation: Northwestern University
- Identification of protein side chains near the membrane-aqueous interface: a site-directed spin labeling study of KcsAAdrian Gross
Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA
Biochemistry 41:1123-8. 2002..The results indicate that residues near the interface can be identified on the basis of their high rates of collision with the headgroup region of the bilayer...
- Potassium channel gating observed with site-directed mass taggingBrent L Kelly
Department of Molecular Pharmacology and Biological Chemistry, Northwestern University School of Medicine, 303 East Chicago Avenue, Chicago, Illinois 60611, USA
Nat Struct Biol 10:280-4. 2003..The results indicate that KcsA is a dynamically modular molecule; the extracellular half of the membrane-spanning region is held rigid during gating, while the intracellular half undergoes a significant conformational change...
- Structural basis of TEA blockade in a model potassium channelMichael J Lenaeus
Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, 303 East Chicago Avenue, Chicago, Illinois 60611, USA
Nat Struct Mol Biol 12:454-9. 2005..We propose that TEA blocks potassium channels by acting as a potassium analog at the dehydration transition step during permeation...
- The structure of the lipid-embedded potassium channel voltage sensor determined by double-electron-electron resonance spectroscopyMagdalini Vamvouka
Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago, Illinois 60611, USA
Protein Sci 17:506-17. 2008....
- Mass spectrometric studies on potassium channelsAdrian Gross; Fiscal Year: 2003..It is anticipated that results from this study will provide new insight into the general structural layout of Shaker. ..