P Greenland

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Commentary: lifelong prevention of atherosclerosis: the critical importance of major risk factor exposures
    Philip Greenland
    Department of Preventive Medicine and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Epidemiol 31:1129-34. 2002
  2. ncbi request reprint Impact of minor electrocardiographic ST-segment and/or T-wave abnormalities on cardiovascular mortality during long-term follow-up
    Philip Greenland
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Am J Cardiol 91:1068-74. 2003
  3. ncbi request reprint Major risk factors as antecedents of fatal and nonfatal coronary heart disease events
    Philip Greenland
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    JAMA 290:891-7. 2003
  4. ncbi request reprint Coronary computed tomography in coronary risk assessment
    Philip Greenland
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    J Cardiopulm Rehabil 25:3-10. 2005
  5. ncbi request reprint Relationship of blood pressure to 25-year mortality due to coronary heart disease, cardiovascular diseases, and all causes in young adult men: the Chicago Heart Association Detection Project in Industry
    K Miura
    Northwestern University Medical School, Department of Preventive Medicine, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611-4402, USA
    Arch Intern Med 161:1501-8. 2001
  6. ncbi request reprint Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment
    M M McDermott
    Department of Medicine, Northwestern University Medical School, Chicago, IL, USA
    JAMA 286:1599-606. 2001
  7. ncbi request reprint Relationship of baseline serum cholesterol levels in 3 large cohorts of younger men to long-term coronary, cardiovascular, and all-cause mortality and to longevity
    J Stamler
    Northwestern University Medical School, Department of Preventive Medicine, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611 4402 USA
    JAMA 284:311-8. 2000
  8. ncbi request reprint Association of nonspecific minor ST-T abnormalities with cardiovascular mortality: the Chicago Western Electric Study
    M L Daviglus
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, Ill 60611, USA
    JAMA 281:530-6. 1999
  9. ncbi request reprint Peripheral arterial disease in African Americans: clinical characteristics, leg symptoms, and lower extremity functioning
    Cheryl Rucker-Whitaker
    Department of Preventive Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 52:922-30. 2004
  10. ncbi request reprint The ankle brachial index is associated with leg function and physical activity: the Walking and Leg Circulation Study
    Mary Mcgrae McDermott
    Feinberg School of Medicine at Northwestern University and Catholic Health Partners, Chicago, Illinois, USA
    Ann Intern Med 136:873-83. 2002

Research Grants

  1. Research Training in CVD Epidemiology and Prevention
    Philip Greenland; Fiscal Year: 2007
  2. Northwestern University Mentored Scholars Program
    Philip Greenland; Fiscal Year: 2006
  3. NORTHWESTERN UNIVERSITY CLINICAL RESEARCH CURRICULUM
    Philip Greenland; Fiscal Year: 2004
  4. Epidemiology of CV and Non-CV Risk in Chicago
    Philip Greenland; Fiscal Year: 2004
  5. EPIDEMIOLOGY OF CV AND NON-CV RISK IN 4 COHORTS
    Philip Greenland; Fiscal Year: 2001

Detail Information

Publications92

  1. ncbi request reprint Commentary: lifelong prevention of atherosclerosis: the critical importance of major risk factor exposures
    Philip Greenland
    Department of Preventive Medicine and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Epidemiol 31:1129-34. 2002
  2. ncbi request reprint Impact of minor electrocardiographic ST-segment and/or T-wave abnormalities on cardiovascular mortality during long-term follow-up
    Philip Greenland
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Am J Cardiol 91:1068-74. 2003
    ....
  3. ncbi request reprint Major risk factors as antecedents of fatal and nonfatal coronary heart disease events
    Philip Greenland
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    JAMA 290:891-7. 2003
    ....
  4. ncbi request reprint Coronary computed tomography in coronary risk assessment
    Philip Greenland
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    J Cardiopulm Rehabil 25:3-10. 2005
  5. ncbi request reprint Relationship of blood pressure to 25-year mortality due to coronary heart disease, cardiovascular diseases, and all causes in young adult men: the Chicago Heart Association Detection Project in Industry
    K Miura
    Northwestern University Medical School, Department of Preventive Medicine, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611-4402, USA
    Arch Intern Med 161:1501-8. 2001
    ..Population-wide primary prevention, early detection, and control of higher BP are indicated from young adulthood on...
  6. ncbi request reprint Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment
    M M McDermott
    Department of Medicine, Northwestern University Medical School, Chicago, IL, USA
    JAMA 286:1599-606. 2001
    ..Persons with lower-extremity peripheral arterial disease (PAD) are often asymptomatic or have leg symptoms other than intermittent claudication (IC)...
  7. ncbi request reprint Relationship of baseline serum cholesterol levels in 3 large cohorts of younger men to long-term coronary, cardiovascular, and all-cause mortality and to longevity
    J Stamler
    Northwestern University Medical School, Department of Preventive Medicine, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611 4402 USA
    JAMA 284:311-8. 2000
    ..However, findings for younger people are limited, and the value of detecting and treating hypercholesterolemia in younger adults is debated...
  8. ncbi request reprint Association of nonspecific minor ST-T abnormalities with cardiovascular mortality: the Chicago Western Electric Study
    M L Daviglus
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, Ill 60611, USA
    JAMA 281:530-6. 1999
    ..Minor electrocardiographic (ECG) ST-T abnormalities are common, but their prognostic importance has not been fully determined...
  9. ncbi request reprint Peripheral arterial disease in African Americans: clinical characteristics, leg symptoms, and lower extremity functioning
    Cheryl Rucker-Whitaker
    Department of Preventive Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 52:922-30. 2004
    ..The describe peripheral arterial disease (PAD) in African Americans, and compare findings in African Americans and whites with PAD...
  10. ncbi request reprint The ankle brachial index is associated with leg function and physical activity: the Walking and Leg Circulation Study
    Mary Mcgrae McDermott
    Feinberg School of Medicine at Northwestern University and Catholic Health Partners, Chicago, Illinois, USA
    Ann Intern Med 136:873-83. 2002
    ..The ankle brachial index (ABI) is a noninvasive, reliable measure of lower-extremity ischemia. However, the relationship between ABI and lower-extremity function has not been well studied...
  11. ncbi request reprint A pilot exercise intervention to improve lower extremity functioning in peripheral arterial disease unaccompanied by intermittent claudication
    Mary M McDermott
    Northwestern University s Feinberg School of Medicine, Chicago, Ill, USA
    J Cardiopulm Rehabil 24:187-96. 2004
    ..A pilot study was conducted to test the feasibility of supervised treadmill exercise training to improve functioning in study participants with peripheral arterial disease who did not have classical symptoms of intermittent claudication...
  12. doi request reprint Multimarker prediction of coronary heart disease risk: the Women's Health Initiative
    Hyeon Chang Kim
    Department of Preventive Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Am Coll Cardiol 55:2080-91. 2010
    ..The aim of this study was to investigate whether multiple biomarkers contribute to improved coronary heart disease (CHD) risk prediction in post-menopausal women compared with assessment using traditional risk factors (TRFs) only...
  13. pmc Framingham risk score and prediction of coronary heart disease death in young men
    Jarett D Berry
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Am Heart J 154:80-6. 2007
    ..Although prediction with individual risk factors has been tested in individuals <30 years, current multivariate risk prediction strategies have not been applied to prediction of clinical CHD in this age range...
  14. pmc Prevalence and significance of unrecognized lower extremity peripheral arterial disease in general medicine practice*
    M M McDermott
    Department of Medicine, Northwestern University Medical School, Chicago, IL, USA
    J Gen Intern Med 16:384-90. 2001
    ....
  15. pmc Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study
    Himabindu Vidula
    Feinberg School of Medicine, Northwestern University, Chicago, Illinois University of California at San Diego, San Diego, California, USA
    Ann Intern Med 148:85-93. 2008
    ..Traditional atherosclerotic risk factors predict long-term cardiovascular disease events but are poor predictors of near-term events...
  16. pmc Leg symptoms, the ankle-brachial index, and walking ability in patients with peripheral arterial disease
    M M McDermott
    Department of Medicine, Northwestern University Medical School, Chicago, Ill, USA
    J Gen Intern Med 14:173-81. 1999
    ..CONCLUSIONS: Both PAD-related leg symptoms and ABI predict patient-perceived walking ability in PAD...
  17. ncbi request reprint Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals
    Philip Greenland
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 90502, USA
    JAMA 291:210-5. 2004
    ..Although the Framingham Risk Score (FRS) is often recommended for this, it has been suggested that risk assessment may be improved by additional tests such as coronary artery calcium scoring (CACS)...
  18. ncbi request reprint Clinical practice. Selecting asymptomatic patients for coronary computed tomography or electrocardiographic exercise testing
    Philip Greenland
    Department of Preventive Medicine, Feinberg School of Medicine at Northwestern University, Chicago, USA
    N Engl J Med 349:465-73. 2003
  19. pmc The relation between body size perception and change in body mass index over 13 years: the Coronary Artery Risk Development in Young Adults (CARDIA) study
    Elizabeth Lynch
    Department of Preventive Medicine, Rush University, 1700 West Van Buren, Chicago, IL 60612, USA
    Am J Epidemiol 169:857-66. 2009
    ..12 vs. 0.27 BMI units; P = 0.04). Results for men showed fewer and weaker associations. When obese women perceive themselves as obese and feel that their body size is too large, they gain less weight over time...
  20. pmc Coronary artery calcium score and risk classification for coronary heart disease prediction
    Tamar S Polonsky
    Department of Preventive Medicine, Northwestern University, Chicago, Illinois, USA
    JAMA 303:1610-6. 2010
    ..The coronary artery calcium score (CACS) has been shown to predict future coronary heart disease (CHD) events. However, the extent to which adding CACS to traditional CHD risk factors improves classification of risk is unclear...
  21. ncbi request reprint Associations of weight change and weight variability with cardiovascular and all-cause mortality in the Chicago Western Electric Company Study
    A R Dyer
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL 60611 4402, USA
    Am J Epidemiol 152:324-33. 2000
    ..These results indicate that an association between weight loss and mortality may not persist beyond 15 years, and that weight variability may not be related to mortality independently of weight loss or weight gain...
  22. ncbi request reprint Risk factors for coronary heart disease in men 18 to 39 years of age
    E L Navas-Nacher
    452 West Aldine Avenue, No. 408, Chicago, IL 60657, USA
    Ann Intern Med 134:433-9. 2001
    ..These data may help in formulating appropriate strategies to identify young men at heightened risk for death from coronary heart disease in later adulthood...
  23. ncbi request reprint Pulse pressure compared with other blood pressure indexes in the prediction of 25-year cardiovascular and all-cause mortality rates: The Chicago Heart Association Detection Project in Industry Study
    K Miura
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL 60611-4402, USA
    Hypertension 38:232-7. 2001
    ..In conclusion, these data indicate that the long-term risk of high BP should be assessed mainly on the basis of SBP or of SBP and DBP together, not on the basis of PP, in apparently healthy adults...
  24. ncbi request reprint Predictive utility of pulse pressure and other blood pressure measures for cardiovascular outcomes
    William J Mosley
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago
    Hypertension 49:1256-64. 2007
    ..These findings support the approach of current guidelines in the use of systolic and diastolic blood pressure to assess risk and the need for treatment...
  25. ncbi request reprint Association of nonmelanoma skin cancer with second malignancy
    Carol A Rosenberg
    Department of Medicine, Evanston Northwestern Healthcare, Evanston, Illinois 60201, USA
    Cancer 100:130-8. 2004
    ..Heightened risks of second cancers have been reported in patients with nonmelanoma cancer of the skin (NMSC), but this association has not been studied in a large, ethnically diverse, multigeographic population...
  26. ncbi request reprint Middle age cardiovascular risk factors and abdominal aortic aneurysm in older age
    Miriam B Rodin
    Division of Geriatrics, Department of Medicine, University of Chicago Pritzker School of Medicine, Chicago, USA
    Hypertension 42:61-8. 2003
    ..It is concluded that major cardiovascular risk factors--serum cholesterol, smoking, and blood pressure--in middle age relate significantly to risk of abdominal aortic aneurysm in persons surviving into older age...
  27. ncbi request reprint Higher blood pressure in middle-aged American adults with less education-role of multiple dietary factors: the INTERMAP study
    J Stamler
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    J Hum Hypertens 17:655-775. 2003
    ..Special efforts to improve eating patterns of less educated strata can contribute importantly to overcoming this and related health disparities in the population...
  28. ncbi request reprint Prevalence and cardiovascular disease correlates of low cardiorespiratory fitness in adolescents and adults
    Mercedes R Carnethon
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    JAMA 294:2981-8. 2005
    ....
  29. ncbi request reprint Midlife body mass index and hospitalization and mortality in older age
    Lijing L Yan
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    JAMA 295:190-8. 2006
    ....
  30. ncbi request reprint Physical performance in peripheral arterial disease: a slower rate of decline in patients who walk more
    Mary Mcgrae McDermott
    Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Ann Intern Med 144:10-20. 2006
    ..However, it is unknown whether patients with PAD who walk for exercise regularly have less functional decline than those with less walking activity...
  31. ncbi request reprint Functional decline in lower-extremity peripheral arterial disease: associations with comorbidity, gender, and race
    Mary M McDermott
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Vasc Surg 42:1131-7. 2005
    ..We also determined whether female sex and black race were associated with greater functional decline than male sex and white race, respectively, in PAD...
  32. ncbi request reprint Narrative review: Assessment of C-reactive protein in risk prediction for cardiovascular disease
    Donald M Lloyd-Jones
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Ann Intern Med 145:35-42. 2006
    ..The authors propose that many questions still must be addressed before CRP is incorporated into risk prediction algorithms and before universal screening with CRP can be recommended...
  33. ncbi request reprint Cutaneous melanoma in postmenopausal women after nonmelanoma skin carcinoma: the Women's Health Initiative Observational Study
    Carol A Rosenberg
    Department of Medicine, Evanston Northwestern Healthcare, Evanston, Illinois 60201, USA
    Cancer 106:654-63. 2006
    ....
  34. ncbi request reprint Relationship of fruit and vegetable consumption in middle-aged men to medicare expenditures in older age: the Chicago Western Electric Study
    Martha L Daviglus
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Am Diet Assoc 105:1735-44. 2005
    ..High fruit and vegetable intake is associated with lower risk of hypertension, cardiovascular disease, and cancer. Little is known about the relationship of fruit and vegetable intake to health care expenditures...
  35. ncbi request reprint Racial/Ethnic differences in subclinical atherosclerosis among adults with diabetes: the multiethnic study of atherosclerosis
    Mercedes R Carnethon
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Diabetes Care 28:2768-70. 2005
  36. ncbi request reprint D-dimer and inflammatory markers as predictors of functional decline in men and women with and without peripheral arterial disease
    Mary M McDermott
    Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Am Geriatr Soc 53:1688-96. 2005
    ..To determine whether higher circulating levels of inflammatory and thrombotic markers are associated with greater decline in lower extremity performance...
  37. ncbi request reprint Cardiovascular risk profile earlier in life and Medicare costs in the last year of life
    Martha L Daviglus
    Department of Preventive Medicine, Feinberg School of Medicine, Northwesten University, Chicago, Ill 60611, USA
    Arch Intern Med 165:1028-34. 2005
    ..However, it is unknown whether cardiovascular risk profile earlier in life influences health care costs in the last year of life. This study addresses this question...
  38. doi request reprint Attitudes and behavior of peripheral arterial disease patients toward influencing their physician's prescription of cholesterol-lowering medication
    Mary M McDermott
    Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Vasc Med 15:83-90. 2010
    ..Clinical Trial Registration - URL: http://www.clinicaltrials.gov. Unique identifier: NCT00217919...
  39. pmc Obesity, weight change, and functional decline in peripheral arterial disease
    Mary M McDermott
    Department of Medicine, Northwestern University s Feinberg School of Medicine, Chicago, IL 60611, USA
    J Vasc Surg 43:1198-204. 2006
    ..We hypothesized that baseline obesity and weight gain during follow-up would each be associated with functional declines in persons with PAD...
  40. ncbi request reprint LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Samia Mora
    Center for Cardiovascular Disease Prevention, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Atherosclerosis 192:211-7. 2007
    ..Previous studies showing that smaller low-density lipoprotein (LDL) size is associated with greater atherosclerotic risk did not adequately control for small and large LDL particle correlation...
  41. ncbi request reprint Resting heart rate in middle age and diabetes development in older age
    Mercedes R Carnethon
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Diabetes Care 31:335-9. 2008
    ....
  42. ncbi request reprint Association of traditional risk factors with cardiovascular death across 0 to 10, 10 to 20, and >20 years follow-up in men and women
    Jarett D Berry
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 101:89-94. 2008
    ..In women, the increased risk associated with both diabetes mellitus and smoking was most prominent in the early follow-up periods...
  43. doi request reprint Post-myocardial infarction beta-blocker therapy: the bradycardia conundrum. Rationale and design for the Pacemaker & beta-blocker therapy post-MI (PACE-MI) trial
    Jeffrey J Goldberger
    Bluhm Cardiovascular Center and the Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Am Heart J 155:455-64. 2008
    ..The primary end point is the composite end point of total mortality plus nonfatal reinfarction...
  44. ncbi request reprint Social avoidance and long-term risk for cardiovascular disease death in healthy men: the Western Electric study
    Jarett D Berry
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Ann Epidemiol 17:591-6. 2007
    ..Thus, we sought to examine the association between SA and CVD, coronary heart disease (CHD), and non-CVD death...
  45. ncbi request reprint Major and minor ECG abnormalities in asymptomatic women and risk of cardiovascular events and mortality
    Pablo Denes
    Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Ill 60611, USA
    JAMA 297:978-85. 2007
    ..There is no information on the effect, if any, of hormonal treatment on the prognostic value of the ECG...
  46. ncbi request reprint Association of ethnicity and socioeconomic status with judgments of body size: the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Elizabeth Lynch
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60601, USA
    Am J Epidemiol 165:1055-62. 2007
    ..Learning to make medically accurate judgments of healthy body size may increase the motivation to lose weight in some persons...
  47. pmc Risk factor burden in middle age and lifetime risks for cardiovascular and non-cardiovascular death (Chicago Heart Association Detection Project in Industry)
    Donald M Lloyd-Jones
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Am J Cardiol 99:535-40. 2007
    ..These results should encourage efforts aimed at preventing the development of risk factors in younger subjects to decrease CVD mortality and promote longevity...
  48. ncbi request reprint Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer
    Brian C H Chiu
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 North Lake Shore Drive, Suite 1102, Chicago, IL 60611 4402, USA
    Cancer Epidemiol Biomarkers Prev 15:2348-54. 2006
    ..We analyzed data from a cohort study to investigate associations of interviewer-measured BMI and PLG with risk of NHL mortality and to explore associations with leukemia and multiple myeloma...
  49. ncbi request reprint Cardiovascular disease risk factor knowledge in young adults and 10-year change in risk factors: the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Elizabeth B Lynch
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 4402, USA
    Am J Epidemiol 164:1171-9. 2006
    ..06) but was unrelated to other risk factor changes. Knowledge of CVD risk factors was very low in these young adults but increased with the presence of risk factors. Knowledge alone did not predict 10-year changes in risk factors...
  50. pmc Association of electrocardiographic abnormalities with coronary artery calcium and carotid artery intima-media thickness in individuals without clinical coronary heart disease (from the Multi-Ethnic Study of Atherosclerosis [MESA])
    Donald M Lloyd-Jones
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 104:1086-91. 2009
    ..Lack of association remained consistent when using log CAC and CC-IMT as continuous variables. In conclusion, ECG abnormalities are not associated with markers of subclinical atherosclerosis in a large multiethnic cohort...
  51. ncbi request reprint Comparison of risk factors for cardiovascular mortality in black and white adults
    Mercedes R Carnethon
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    Arch Intern Med 166:1196-202. 2006
    ..We investigated whether traditional cardiovascular disease (CVD) risk factors were similarly associated with CVD mortality in black and white men and women...
  52. ncbi request reprint Education, 15-year risk factor progression, and coronary artery calcium in young adulthood and early middle age: the Coronary Artery Risk Development in Young Adults study
    Lijing L Yan
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    JAMA 295:1793-800. 2006
    ....
  53. ncbi request reprint Relation of nutrient intake to microalbuminuria in nondiabetic middle-aged men and women: International Population Study on Macronutrients and Blood Pressure (INTERMAP)
    Martha L Daviglus
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Am J Kidney Dis 45:256-66. 2005
    ..Microalbuminuria (MA) is a risk factor for cardiovascular and renal disease. However, little is known about the relation of nutritional factors to MA, especially in individuals without diabetes...
  54. ncbi request reprint Lower extremity performance is associated with daily life physical activity in individuals with and without peripheral arterial disease
    Mary Mcgrae McDermott
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA
    J Am Geriatr Soc 50:247-55. 2002
    ..To determine whether persons with poorer lower extremity functioning have reduced physical activity levels...
  55. ncbi request reprint Body mass index in middle age and health-related quality of life in older age: the Chicago heart association detection project in industry study
    Martha L Daviglus
    Department of Preventive Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Arch Intern Med 163:2448-55. 2003
    ..This study evaluates whether BMI in middle age is related to health-related quality of life in older age...
  56. ncbi request reprint Favorable cardiovascular risk profile in middle age and health-related quality of life in older age
    Martha L Daviglus
    Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Arch Intern Med 163:2460-8. 2003
    ..Few data exist on this important issue. This study evaluates the relationship of midlife low-risk status to quality of life and illness in older age...
  57. ncbi request reprint BMI and health-related quality of life in adults 65 years and older
    Lijing L Yan
    Feinberg School of Medicine, Department of Preventive Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Obes Res 12:69-76. 2004
    ..To examine relationships of BMI with health-related quality of life in adults 65 years and older...
  58. ncbi request reprint D-dimer, inflammatory markers, and lower extremity functioning in patients with and without peripheral arterial disease
    Mary Mcgrae McDermott
    Department of Medicine, Northwestern University s Feinberg School of Medicine, Chicago, IL, USA
    Circulation 107:3191-8. 2003
    ..We determined whether higher levels of D-dimer, C-reactive protein (CRP), fibrinogen, and serum amyloid A are associated independently with functional impairment in patients with and without peripheral arterial disease (PAD)...
  59. ncbi request reprint Statin use and leg functioning in patients with and without lower-extremity peripheral arterial disease
    Mary Mcgrae McDermott
    Feinberg School of Medicine at Northwestern University, Chicago, Ill, USA
    Circulation 107:757-61. 2003
    ..We determined whether statin use (versus nonuse) is associated with superior lower-extremity functioning independently of cholesterol levels and other confounders in patients with and without peripheral arterial disease...
  60. ncbi request reprint Long-term consequences of body mass index for cardiovascular mortality: the Chicago Heart Association Detection Project in Industry study
    Alan R Dyer
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL 60611 4402, USA
    Ann Epidemiol 14:101-8. 2004
    ....
  61. ncbi request reprint Fish consumption and incidence of stroke: a meta-analysis of cohort studies
    Ka He
    Department of Preventive Medicine, The Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611, USA
    Stroke 35:1538-42. 2004
    ..Results from observational studies on fish consumption and risk of stroke are inconsistent. We quantitatively assessed the relationship between fish intake and incidence of stroke using a meta-analysis of cohort studies...
  62. ncbi request reprint Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies
    Ka He
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1102, Chicago, Ill 60611, USA
    Circulation 109:2705-11. 2004
    ..Results from observational studies on fish consumption and coronary heart disease (CHD) mortality are inconsistent...
  63. ncbi request reprint Estimating laboratory precision of urinary albumin excretion and other urinary measures in the International Study on Macronutrients and Blood Pressure
    Alan R Dyer
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 4402, USA
    Am J Epidemiol 160:287-94. 2004
    ..4%, 11.4%, and 6.4%, respectively. Results indicate that mean and median CV are not equivalent to %TE and that values below the detection limit can markedly affect estimates and should be excluded...
  64. ncbi request reprint Comparison of low risk and higher risk profiles in middle age to frequency and quantity of coronary artery calcium years later
    Martha L Daviglus
    Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 94:367-9. 2004
    ..Despite adverse changes in risk factors, the prevalence of measurable CAC and mean CAC scores were less for LR participants than for non-LR participants (60% vs 77%, p = 0.09, and 217 vs 443, p = 0.05, respectively)...
  65. ncbi request reprint Eight-year blood pressure change in middle-aged men: relationship to multiple nutrients
    Jeremiah Stamler
    Northwestern University Medical School, Chicago, Illinois, USA
    Hypertension 39:1000-6. 2002
    ..These findings support the concept that multiple macro- and micronutrients, alcohol intake, and calorie imbalance relate prospectively to blood pressure change...
  66. ncbi request reprint Relation of body mass index in young adulthood and middle age to Medicare expenditures in older age
    Martha L Daviglus
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    JAMA 292:2743-9. 2004
    ..However, little is known about the impact of body mass index (BMI) earlier in life on Medicare expenditures (cardiovascular disease [CVD]-related, diabetes-related, and total) in older age...
  67. ncbi request reprint Evaluation of measures of urinary albumin excretion in epidemiologic studies
    Alan R Dyer
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 4402, USA
    Am J Epidemiol 160:1122-31. 2004
    ..188 for UAC vs. 0.211 for UAE) because of high correlation between body mass index and creatinine level. Thus, UAC and ACR are acceptable alternatives to the more complex UAE, and the simpler UAC may be preferable to ACR in some respects...
  68. ncbi request reprint Inflammatory and thrombotic blood markers and walking-related disability in men and women with and without peripheral arterial disease
    Mary M McDermott
    Feinberg School of Medicine, Northwestern University, 675 N St Clair, Chicago, IL 60611, USA
    J Am Geriatr Soc 52:1888-94. 2004
    ..To determine whether higher circulating levels of thrombotic and inflammatory markers are associated with greater disability...
  69. ncbi request reprint Estrogen and progestin use and the QT interval in postmenopausal women
    Alan H Kadish
    Division of Cardiology, Department of Internal Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Ann Noninvasive Electrocardiol 9:366-74. 2004
    ..To determine whether menopausal hormone therapy alters the QT interval in primarily healthy postmenopausal women...
  70. ncbi request reprint Favorable cardiovascular risk profile in young women and long-term risk of cardiovascular and all-cause mortality
    Martha L Daviglus
    Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Ill 60611, USA
    JAMA 292:1588-92. 2004
    ..For women, impact of cardiovascular risk factors measured in young adulthood, particularly favorable (low-risk) profile, on mortality has been difficult to assess due to low short-term death rates...
  71. ncbi request reprint Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms
    Mary Mcgrae McDermott
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill, USA
    JAMA 292:453-61. 2004
    ..However, relations between these clinical characteristics and objectively measured functional decline are unknown...
  72. ncbi request reprint Relation of levels of hemostatic factors and inflammatory markers to the ankle brachial index
    Mary M McDermott
    Feinberg School of Medicine, Northwestern University, 675 N St Clair, Chicago, IL 60611, USA
    Am J Cardiol 92:194-9. 2003
    ..We conclude that D-dimer levels may be more sensitive than other blood markers for measuring the extent of atherosclerosis in lower extremity arteries...
  73. ncbi request reprint Accuracy of estimating exercise prescription intensity in patients with left ventricular systolic dysfunction
    T A Strzelczyk
    Division of Cardiology, Department of Medicine, Northwestern University Medical School, Northwestern Memorial Hospital, Chicago, Illinois, USA
    J Cardiopulm Rehabil 21:158-63. 2001
    ..The purpose of this study was to determine if these methods correlate with an exercise intensity below VT in LVSD patients...
  74. ncbi request reprint Oats and soy in lipid-lowering diets for women with hypercholesterolemia: is there synergy?
    L Van Horn
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL 60611, USA
    J Am Diet Assoc 101:1319-25. 2001
    ..Intervention and clinical visits were conducted in these same facilities...
  75. ncbi request reprint Gait alterations associated with walking impairment in people with peripheral arterial disease with and without intermittent claudication
    M M McDermott
    Department of Medicine, Northwestern University Medical School, Chicago, Illinois, USA
    J Am Geriatr Soc 49:747-54. 2001
    ..ABI was more closely associated with cadence than step length. Future studies should assess the effect of exercise programs and revascularization on cadence and step length in PAD...
  76. ncbi request reprint Seven-year tracking of dietary factors in young adults: the CARDIA study
    J E Dunn
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, Illinois 60611 4402, USA
    Am J Prev Med 18:38-45. 2000
    ..This report determines the extent to which young adults in the highest and lowest intake quintiles of 13 nutrients remain in the same or adjacent quintiles (i.e., "tracked") relative to each other, over 7 years...
  77. pmc Atherosclerotic risk factors are less intensively treated in patients with peripheral arterial disease than in patients with coronary artery disease
    M M McDermott
    Department of Medicine, Northwestern University Medical School Chicago, IL 60611, USA
    J Gen Intern Med 12:209-15. 1997
    ..8, p = .01). CONCLUSIONS: Atherosclerotic risk factors are less intensively treated among PAD patients than CAD patients. A number of possible explanations could account for these disparities in therapeutic intensity...
  78. ncbi request reprint How low-risk is a coronary calcium score of zero? The importance of conditional probability
    Philip Greenland
    Circulation 117:1627-9. 2008
  79. ncbi request reprint Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Gerontol A Biol Sci Med Sci 63:369-75. 2008
    ..This study examines associations between current use, duration, and potency of statin medications and incident frailty in initially nonfrail women 65 years old or older...
  80. ncbi request reprint Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group III: risk assessment in persons with diabetes
    Rita F Redberg
    Circulation 105:e144-52. 2002
  81. ncbi request reprint Association between cardiovascular outcomes and antihypertensive drug treatment in older women
    Sylvia Wassertheil-Smoller
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    JAMA 292:2849-59. 2004
    ..However, many patients with hypertension require treatment with more than 1 drug class to achieve blood pressure control. The relative benefits or risks of 2-drug-class combinations are not well known...
  82. ncbi request reprint Coronary artery calcium scores and risk for cardiovascular events in women classified as "low risk" based on Framingham risk score: the multi-ethnic study of atherosclerosis (MESA)
    Susan G Lakoski
    Department of Internal Medicine Cardiology, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Intern Med 167:2437-42. 2007
    ..Based on population survey data, 95% of American women are considered at low risk based on FRS...
  83. ncbi request reprint Walking compared with vigorous exercise for the prevention of cardiovascular events in women
    JoAnn E Manson
    Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston 02215, USA
    N Engl J Med 347:716-25. 2002
    ..The role of walking, as compared with vigorous exercise, in the prevention of cardiovascular disease remains controversial. Data for women who are members of minority racial or ethnic groups are particularly sparse...
  84. ncbi request reprint Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study
    Karen L Margolis
    Hennepin County Medical Center, and Berman Center for Outcomes and Clinical Research, 825 S Eighth Street, Minneapolis, MN 55404, USA
    Arch Intern Med 165:500-8. 2005
    ..Our objective was to describe the relation between the baseline white blood cell (WBC) count and future CVD events and mortality in postmenopausal women...
  85. ncbi request reprint Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute Howard University, Washington, DC, USA
    JAMA 295:655-66. 2006
    ..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed...
  86. ncbi request reprint Relation of vegetable, fruit, and meat intake to 7-year blood pressure change in middle-aged men: the Chicago Western Electric Study
    Katsuyuki Miura
    Department of Public Health, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Ishikawa 920 0293, Japan
    Am J Epidemiol 159:572-80. 2004
    ..05). These results support the concept that diets higher in fruits and vegetables and lower in meats (except fish) may reduce the risk of developing high BP...
  87. ncbi request reprint Depression and cardiovascular sequelae in postmenopausal women. The Women's Health Initiative (WHI)
    Sylvia Wassertheil-Smoller
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Arch Intern Med 164:289-98. 2004
    ..We describe prevalence, cardiovascular correlates, and relationship to subsequent cardiovascular events of depressive symptoms among generally healthy postmenopausal women...
  88. ncbi request reprint From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II
    Morteza Naghavi
    The Center for Vulnerable Plaque Research, University of Texas Houston, The Texas Heart Institute, and President Bush Center for Cardiovascular Health, Memorial Hermann Hospital, Houston, USA
    Circulation 108:1772-8. 2003
    ..We encourage healthcare policy makers to promote translational research for screening and treatment of vulnerable patients...
  89. ncbi request reprint From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I
    Morteza Naghavi
    The Center for Vulnerable Plaque Research, University of Texas Houston, The Texas Heart Institute, and President Bush Center for Cardiovascular Health, Memorial Hermann Hospital, Houston, USA
    Circulation 108:1664-72. 2003
    ..We encourage healthcare policy makers to promote translational research for screening and treatment of vulnerable patients...
  90. ncbi request reprint Family history of premature coronary heart disease and coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Cardiac MRI PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Circulation 116:619-26. 2007
    ....
  91. ncbi request reprint Multi-ethnic study of atherosclerosis: objectives and design
    Diane E Bild
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
    Am J Epidemiol 156:871-81. 2002
    ....
  92. ncbi request reprint Time to end the mixed--and often incorrect--messages about prevention and treatment of atherosclerotic cardiovascular disease
    Philip Greenland
    J Am Coll Cardiol 50:2133-5. 2007

Research Grants18

  1. Research Training in CVD Epidemiology and Prevention
    Philip Greenland; Fiscal Year: 2007
    ..An Executive Committee led by the Program Director/PI directs the program and is assisted by an Advisory Committee. Ongoing evaluation and feedback will help assure that programmatic and recruitment goals are met. ..
  2. Northwestern University Mentored Scholars Program
    Philip Greenland; Fiscal Year: 2006
    ..A plan for evaluation is presented that measures the program's success against its objectives outlined above and provides ongoing formative assessment. ..
  3. NORTHWESTERN UNIVERSITY CLINICAL RESEARCH CURRICULUM
    Philip Greenland; Fiscal Year: 2004
    ..The initiation of the program comes at a time of substantial and sustained growth in NUMS' clinical research enterprise. All of these factors make NUMS an ideal site for an National Institute's of Health (NIH)-funded CRCA. ..
  4. Epidemiology of CV and Non-CV Risk in Chicago
    Philip Greenland; Fiscal Year: 2004
    ..abstract_text> ..
  5. EPIDEMIOLOGY OF CV AND NON-CV RISK IN 4 COHORTS
    Philip Greenland; Fiscal Year: 2001
    ....