CARA GOTTARDI

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Phospho-regulation of Beta-catenin adhesion and signaling functions
    Rebecca Leadem Daugherty
    The Integrated Graduate Program in the Life Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Physiology (Bethesda) 22:303-9. 2007
  2. pmc Terminating Wnt signals: a novel nuclear export mechanism targets activated (beta)-catenin
    Meghan E Thorne
    Department of Medicine, Northwestern University, Chicago, IL 60637, USA
    J Cell Biol 171:761-3. 2005
  3. pmc Beta-catenin phosphorylated at serine 45 is spatially uncoupled from beta-catenin phosphorylated in the GSK3 domain: implications for signaling
    Meghan T Maher
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
    PLoS ONE 5:e10184. 2010
  4. pmc Activity of the beta-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion
    Meghan T Maher
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Cell Biol 186:219-28. 2009
  5. pmc Issues associated with assessing nuclear localization of N-terminally unphosphorylated beta-catenin with monoclonal antibody 8E7
    Meghan T Maher
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Biol Direct 4:5. 2009
  6. pmc Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes
    Cara J Gottardi
    Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Cell Biol 167:339-49. 2004
  7. pmc Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling
    Mark Lal
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Hum Mol Genet 17:3105-17. 2008
  8. pmc VE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeability
    Mingzhang Guo
    Department of Surgery, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    Am J Physiol Cell Physiol 294:C977-84. 2008
  9. ncbi request reprint When domestiques rebel: kinesins, cadherins and neuronal proliferation
    Cara J Gottardi
    Nat Cell Biol 7:445-7. 2005
  10. ncbi request reprint Role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions
    Cara J Gottardi
    Department of Cell Biology, School of Medicine, University of Virginia, Charlottesville, VA 22908 0732, USA
    Am J Physiol Cell Physiol 286:C747-56. 2004

Collaborators

Detail Information

Publications12

  1. pmc Phospho-regulation of Beta-catenin adhesion and signaling functions
    Rebecca Leadem Daugherty
    The Integrated Graduate Program in the Life Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Physiology (Bethesda) 22:303-9. 2007
    ..Inputs from various cell-signaling events can therefore impact beta-catenin function, which may be necessary for the finely tuned adhesive and signaling responses required for tissue morphogenesis...
  2. pmc Terminating Wnt signals: a novel nuclear export mechanism targets activated (beta)-catenin
    Meghan E Thorne
    Department of Medicine, Northwestern University, Chicago, IL 60637, USA
    J Cell Biol 171:761-3. 2005
    ..We speculate that cells may use multiple export mechanisms to inhibit beta-catenin signaling in different ways...
  3. pmc Beta-catenin phosphorylated at serine 45 is spatially uncoupled from beta-catenin phosphorylated in the GSK3 domain: implications for signaling
    Meghan T Maher
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
    PLoS ONE 5:e10184. 2010
    ....
  4. pmc Activity of the beta-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion
    Meghan T Maher
    Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Cell Biol 186:219-28. 2009
    ....
  5. pmc Issues associated with assessing nuclear localization of N-terminally unphosphorylated beta-catenin with monoclonal antibody 8E7
    Meghan T Maher
    Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Biol Direct 4:5. 2009
    ....
  6. pmc Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes
    Cara J Gottardi
    Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Cell Biol 167:339-49. 2004
    ..This model explains how cells can control whether beta-catenin is used independently in cell adhesion and nuclear signaling, or competitively so that the two processes are coordinated and interrelated...
  7. pmc Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling
    Mark Lal
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Hum Mol Genet 17:3105-17. 2008
    ..Our results suggest a novel mechanism through which PC1 cleavage may impact upon Wnt-dependent signaling and thereby modulate both developmental processes and cystogenesis...
  8. pmc VE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeability
    Mingzhang Guo
    Department of Surgery, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    Am J Physiol Cell Physiol 294:C977-84. 2008
    ..Taken together, these data suggest that inflammatory agents like histamine cause a transient and reversible disruption of binding between beta-catenin and VE-cadherin, during which endothelial permeability is elevated...
  9. ncbi request reprint When domestiques rebel: kinesins, cadherins and neuronal proliferation
    Cara J Gottardi
    Nat Cell Biol 7:445-7. 2005
  10. ncbi request reprint Role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions
    Cara J Gottardi
    Department of Cell Biology, School of Medicine, University of Virginia, Charlottesville, VA 22908 0732, USA
    Am J Physiol Cell Physiol 286:C747-56. 2004
    ....
  11. pmc Terminal regions of beta-catenin come into view
    Cara J Gottardi
    Structure 16:336-8. 2008
  12. pmc Molecular components of the adherens junction
    Carien M Niessen
    Center for Molecular Medicine, University of Cologne, LFI, 05, Room 59, Joseph Stelzmannstrasse 9, D 50931 Cologne, Germany
    Biochim Biophys Acta 1778:562-71. 2008
    ..The molecular machineries that organize these adhesion receptor complexes into higher order junction structures, and the functional consequences of this junctional organization will be discussed...