Research Topics
Species | Annette M GonzalezSummaryAffiliation: Northwestern University Country: USA Publications
Research Grants
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Detail Information
Publications
Integrin cross-talk in endothelial cells is regulated by protein kinase A and protein phosphatase 1Annette M Gonzalez
Department of Cell and Molecular Biology, The Feinberg School of Medicine at Northwestern University, Chicago, Illinois 60611, USA
J Biol Chem 283:31849-60. 2008..These results indicate a novel mechanism by which beta1 integrin negatively modulates alphavbeta3 integrin-ligand binding via activation of PKA and inhibition of PP1 activity...
Transdominant regulation of integrin function: mechanisms of crosstalkAnnette M Gonzalez
Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Cell Signal 22:578-83. 2010..We conclude with a discussion of how integrin crosstalk impacts the interpretation of integrin inhibitor and knockdown studies in both the laboratory and clinical setting...
Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivoAnnette M Gonzalez
Department of Cell and Molecular Biology, The Feinberg School of Medicine at Northwestern University, Chicago, IL 60611, USA
Proc Natl Acad Sci U S A 99:16075-80. 2002..We propose a model based on these data that reconcile apparent discrepancies in the recent literature with regard to the role of the alphavbeta3 integrin in angiogenesis...
Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strengthRamona Bhattacharya
Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA
J Cell Sci 122:1390-400. 2009..These differences require an intact vimentin network. Therefore, vimentin IF recruitment to the cell surface is tightly regulated and modulates the strength of adhesion of cells to their substrate...
Research Grants
- Integrin-Laminin Interactions in Endothelial CellsAnnette Gonzalez; Fiscal Year: 2007..abstract_text> ..
