R D Goldman

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Nuclear lamins: building blocks of nuclear architecture
    Robert D Goldman
    Northwestern University Medical School, Department of Cell and Molecular Biology, Chicago, Illinois 60611, USA
    Genes Dev 16:533-47. 2002
  2. pmc IFAP 300 is common to desmosomes and hemidesmosomes and is a possible linker of intermediate filaments to these junctions
    O Skalli
    Department of Cell, Molecular, and Structural Biology, Northwestern University Medical School, Chicago, Illinois 60611
    J Cell Biol 125:159-70. 1994
  3. pmc Structure and function of a vimentin-associated matrix adhesion in endothelial cells
    M Gonzales
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Mol Biol Cell 12:85-100. 2001
  4. doi request reprint Nuclear lamins in cell regulation and disease
    T Shimi
    Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Cold Spring Harb Symp Quant Biol 75:525-31. 2010
  5. ncbi request reprint The 300-kDa intermediate filament-associated protein (IFAP300) is a hamster plectin ortholog
    B H Clubb
    Department of Cell and Molecular Biology, Northwestern University, Chicago, Illinois 60657, USA
    Biochem Biophys Res Commun 273:183-7. 2000
  6. pmc A role for nuclear lamins in nuclear envelope assembly
    R I Lopez-Soler
    Department of Cell and Molecular Biology, Northwestern University Medical School, 303 East Chicago Avenue, Chicago, IL 60611, USA
    J Cell Biol 154:61-70. 2001
  7. pmc Keratin incorporation into intermediate filament networks is a rapid process
    R K Miller
    Northwestern University Medical School, Department of Cell, Molecular, and Structural Biology, Chicago, Illinois 60611
    J Cell Biol 113:843-55. 1991
  8. pmc Insights into the dynamic properties of keratin intermediate filaments in living epithelial cells
    K H Yoon
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611
    J Cell Biol 153:503-16. 2001
  9. pmc Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription
    Timothy P Spann
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA
    J Cell Biol 156:603-8. 2002
  10. ncbi request reprint The nucleoskeleton: lamins and actin are major players in essential nuclear functions
    Dale K Shumaker
    Northwestern University, Feinberg School of Medicine, Department of Cell and Molecular Biology, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Opin Cell Biol 15:358-66. 2003

Collaborators

  • Katherine Wilson
  • J C Jones
  • R D Moir
  • H Herrmann
  • S A Adam
  • T M Svitkina
  • T Jenuwein
  • Dale K Shumaker
  • Yosef Gruenbaum
  • Thomas Dechat
  • T Shimi
  • Timothy P Spann
  • Kaushik Sengupta
  • Takeshi Shimi
  • Liliana Solimando
  • Ying Hao Chou
  • Anna Mattout
  • Anne E Goldman
  • Ayelet Margalit
  • F W Flitney
  • K H Yoon
  • R I Lopez-Soler
  • M Gonzales
  • V Butin-Israeli
  • B H Clubb
  • M Cristina Cardoso
  • Antje Grunwald
  • Katrin Pfleghaar
  • Sergei V Strelkov
  • Ueli Aebi
  • Melissa Mendez
  • Lynne Chang
  • Boris Grin
  • Frederick W Flitney
  • Maria Eriksson
  • Satya Khuon
  • Alexander Kohlmaier
  • Michael R Erdos
  • Matthew R Bozovsky
  • Francis S Collins
  • Reynold I Lopez-Soler
  • Erez Mills
  • Miron Prokocimer
  • Yaron Dayani
  • Edward R Kuczmarski
  • Avital Enosh
  • Alexandra Fridkin
  • Ronit Meyuhas
  • Sui Huang
  • Chen Wang
  • M Yoon
  • T P Spann
  • R Stick
  • B Weksler
  • D Tsuruta
  • S Khuon
  • S B Hopkinson
  • K J Yoon
  • Y H Chou
  • G G Borisy
  • O Skalli
  • R Gagescu
  • R K Miller
  • K Vikstrom

Detail Information

Publications24

  1. ncbi request reprint Nuclear lamins: building blocks of nuclear architecture
    Robert D Goldman
    Northwestern University Medical School, Department of Cell and Molecular Biology, Chicago, Illinois 60611, USA
    Genes Dev 16:533-47. 2002
  2. pmc IFAP 300 is common to desmosomes and hemidesmosomes and is a possible linker of intermediate filaments to these junctions
    O Skalli
    Department of Cell, Molecular, and Structural Biology, Northwestern University Medical School, Chicago, Illinois 60611
    J Cell Biol 125:159-70. 1994
    ....
  3. pmc Structure and function of a vimentin-associated matrix adhesion in endothelial cells
    M Gonzales
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Mol Biol Cell 12:85-100. 2001
    ..Our data indicate that this adhesion structure may play a role in angiogenesis...
  4. doi request reprint Nuclear lamins in cell regulation and disease
    T Shimi
    Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Cold Spring Harb Symp Quant Biol 75:525-31. 2010
    ..Recently, the discovery of numerous mutations in the gene encoding A-type lamins causing the collection of diseases known as laminopathies has provided new insights into the roles of lamins in cellular regulation and differentiation...
  5. ncbi request reprint The 300-kDa intermediate filament-associated protein (IFAP300) is a hamster plectin ortholog
    B H Clubb
    Department of Cell and Molecular Biology, Northwestern University, Chicago, Illinois 60657, USA
    Biochem Biophys Res Commun 273:183-7. 2000
    ..Using immunological cross-reactivity, epitope mapping, and immunoelectron microscopy, we show that IFAP300 is actually the hamster ortholog of plectin...
  6. pmc A role for nuclear lamins in nuclear envelope assembly
    R I Lopez-Soler
    Department of Cell and Molecular Biology, Northwestern University Medical School, 303 East Chicago Avenue, Chicago, IL 60611, USA
    J Cell Biol 154:61-70. 2001
    ..These findings suggest that lamin polymerization is required for both chromatin decondensation and the binding of nuclear membrane precursors during the early stages of normal nuclear envelope assembly...
  7. pmc Keratin incorporation into intermediate filament networks is a rapid process
    R K Miller
    Northwestern University Medical School, Department of Cell, Molecular, and Structural Biology, Chicago, Illinois 60611
    J Cell Biol 113:843-55. 1991
    ..These observations support the idea that keratin-IFs are dynamic cytoskeletal elements...
  8. pmc Insights into the dynamic properties of keratin intermediate filaments in living epithelial cells
    K H Yoon
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611
    J Cell Biol 153:503-16. 2001
    ..This suggests that there are different factors regulating the dynamic properties of different types of IFs within the same cytoplasmic regions...
  9. pmc Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription
    Timothy P Spann
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA
    J Cell Biol 156:603-8. 2002
    ..Furthermore, immunofluorescence observations indicate that this selective inhibition of polymerase II-dependent transcription involves the TATA binding protein, a component of the basal transcription factor TFIID...
  10. ncbi request reprint The nucleoskeleton: lamins and actin are major players in essential nuclear functions
    Dale K Shumaker
    Northwestern University, Feinberg School of Medicine, Department of Cell and Molecular Biology, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Opin Cell Biol 15:358-66. 2003
    ..This range of activities might help to explain why genetic defects in some of the nucleoskeletal proteins contribute to an ever-expanding list of human diseases...
  11. pmc Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
    Robert D Goldman
    Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 101:8963-8. 2004
    ....
  12. ncbi request reprint The nuclear lamina comes of age
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Givat Ram, Jerusalem, 91904 Israel
    Nat Rev Mol Cell Biol 6:21-31. 2005
    ....
  13. ncbi request reprint Nuclear lamins: building blocks of nuclear structure and function
    Robert D Goldman
    Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Novartis Found Symp 264:3-16; discussion 16-21, 227-30. 2005
    ....
  14. pmc The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Cell Biol 181:269-80. 2008
    ..These findings also provide insights into the mechanisms underlying the numerous disease-causing mutations located within the lamin Ig-fold...
  15. pmc Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
    Thomas Dechat
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Genes Dev 22:832-53. 2008
    ..In addition, we discuss recent evidence supporting the importance of lamins in viral infections...
  16. pmc Regulation of nuclear lamin polymerization by importin alpha
    Stephen A Adam
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Biol Chem 283:8462-8. 2008
    ..These results suggest a role for importin alpha in regulating lamin assembly and possibly modulating the interactions of lamins with lamin-binding proteins...
  17. ncbi request reprint The motility and dynamic properties of intermediate filaments and their constituent proteins
    Ying Hao Chou
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Exp Cell Res 313:2236-43. 2007
    ..The recent findings that IF and their precursors are frequently associated with signaling molecules have revealed new functions for IF beyond their more traditional roles as mechanical integrators of cells and tissues...
  18. pmc Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 103:8703-8. 2006
    ..The epigenetic changes described most likely represent molecular mechanisms responsible for the rapid progression of premature aging in HGPS patients...
  19. ncbi request reprint Nuclear lamins, diseases and aging
    Anna Mattout
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Curr Opin Cell Biol 18:335-41. 2006
    ..These diseases, collectively termed laminopathies, affect muscle, adipose, bone, nerve and skin cells and range from muscular dystrophies to accelerated aging...
  20. pmc Functions and dysfunctions of the nuclear lamin Ig-fold domain in nuclear assembly, growth, and Emery-Dreifuss muscular dystrophy
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 102:15494-9. 2005
    ....
  21. ncbi request reprint The nuclear lamina and its functions in the nucleus
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Int Rev Cytol 226:1-62. 2003
    ....