R D Goldman

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi Nuclear lamins: building blocks of nuclear architecture
    Robert D Goldman
    Northwestern University Medical School, Department of Cell and Molecular Biology, Chicago, Illinois 60611, USA
    Genes Dev 16:533-47. 2002
  2. ncbi Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription
    Timothy P Spann
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA
    J Cell Biol 156:603-8. 2002
  3. ncbi Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
    Thomas Dechat
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Genes Dev 22:832-53. 2008
  4. ncbi The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Cell Biol 181:269-80. 2008
  5. ncbi Nuclear lamins: building blocks of nuclear structure and function
    Robert D Goldman
    Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611-3008, USA
    Novartis Found Symp 264:3-16; discussion 16-21, 227-30. 2005
  6. ncbi The nuclear lamina comes of age
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Givat Ram, Jerusalem, 91904 Israel
    Nat Rev Mol Cell Biol 6:21-31. 2005
  7. ncbi Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
    Robert D Goldman
    Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 101:8963-8. 2004
  8. ncbi The nucleoskeleton: lamins and actin are major players in essential nuclear functions
    Dale K Shumaker
    Northwestern University, Feinberg School of Medicine, Department of Cell and Molecular Biology, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Opin Cell Biol 15:358-66. 2003
  9. ncbi The nuclear lamina and its functions in the nucleus
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Int Rev Cytol 226:1-62. 2003
  10. ncbi Nuclear lamins, diseases and aging
    Anna Mattout
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Curr Opin Cell Biol 18:335-41. 2006

Collaborators

  • Katherine Wilson
  • S A Adam
  • T Jenuwein
  • H Herrmann
  • Dale K Shumaker
  • Yosef Gruenbaum
  • Thomas Dechat
  • Timothy P Spann
  • Liliana Solimando
  • Kaushik Sengupta
  • Takeshi Shimi
  • Ying Hao Chou
  • Anna Mattout
  • Ayelet Margalit
  • Anne E Goldman
  • Sergei V Strelkov
  • Ueli Aebi
  • M Cristina Cardoso
  • Katrin Pfleghaar
  • Antje Grunwald
  • Melissa Mendez
  • Ying-Hao Chou
  • Lynne Chang
  • Frederick W Flitney
  • Boris Grin
  • Francis S Collins
  • Maria Eriksson
  • Matthew R Bozovsky
  • Alexander Kohlmaier
  • Satya Khuon
  • Michael R Erdos
  • Reynold I Lopez-Soler
  • Robert D Moir
  • Ronit Meyuhas
  • Avital Enosh
  • Alexandra Fridkin
  • Erez Mills
  • Edward R Kuczmarski
  • Miron Prokocimer
  • Yaron Dayani
  • Sui Huang
  • Chen Wang

Detail Information

Publications14

  1. ncbi Nuclear lamins: building blocks of nuclear architecture
    Robert D Goldman
    Northwestern University Medical School, Department of Cell and Molecular Biology, Chicago, Illinois 60611, USA
    Genes Dev 16:533-47. 2002
  2. ncbi Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription
    Timothy P Spann
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA
    J Cell Biol 156:603-8. 2002
    ..Furthermore, immunofluorescence observations indicate that this selective inhibition of polymerase II-dependent transcription involves the TATA binding protein, a component of the basal transcription factor TFIID...
  3. ncbi Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
    Thomas Dechat
    Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Genes Dev 22:832-53. 2008
    ..In addition, we discuss recent evidence supporting the importance of lamins in viral infections...
  4. ncbi The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Cell Biol 181:269-80. 2008
    ..These findings also provide insights into the mechanisms underlying the numerous disease-causing mutations located within the lamin Ig-fold...
  5. ncbi Nuclear lamins: building blocks of nuclear structure and function
    Robert D Goldman
    Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611-3008, USA
    Novartis Found Symp 264:3-16; discussion 16-21, 227-30. 2005
    ....
  6. ncbi The nuclear lamina comes of age
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Givat Ram, Jerusalem, 91904 Israel
    Nat Rev Mol Cell Biol 6:21-31. 2005
    ....
  7. ncbi Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
    Robert D Goldman
    Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 101:8963-8. 2004
    ....
  8. ncbi The nucleoskeleton: lamins and actin are major players in essential nuclear functions
    Dale K Shumaker
    Northwestern University, Feinberg School of Medicine, Department of Cell and Molecular Biology, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Curr Opin Cell Biol 15:358-66. 2003
    ..This range of activities might help to explain why genetic defects in some of the nucleoskeletal proteins contribute to an ever-expanding list of human diseases...
  9. ncbi The nuclear lamina and its functions in the nucleus
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Int Rev Cytol 226:1-62. 2003
    ....
  10. ncbi Nuclear lamins, diseases and aging
    Anna Mattout
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Curr Opin Cell Biol 18:335-41. 2006
    ..These diseases, collectively termed laminopathies, affect muscle, adipose, bone, nerve and skin cells and range from muscular dystrophies to accelerated aging...
  11. ncbi Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 103:8703-8. 2006
    ..The epigenetic changes described most likely represent molecular mechanisms responsible for the rapid progression of premature aging in HGPS patients...
  12. ncbi The motility and dynamic properties of intermediate filaments and their constituent proteins
    Ying Hao Chou
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Exp Cell Res 313:2236-43. 2007
    ..The recent findings that IF and their precursors are frequently associated with signaling molecules have revealed new functions for IF beyond their more traditional roles as mechanical integrators of cells and tissues...
  13. ncbi Regulation of nuclear lamin polymerization by importin alpha
    Stephen A Adam
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    J Biol Chem 283:8462-8. 2008
    ..These results suggest a role for importin alpha in regulating lamin assembly and possibly modulating the interactions of lamins with lamin-binding proteins...
  14. ncbi Functions and dysfunctions of the nuclear lamin Ig-fold domain in nuclear assembly, growth, and Emery-Dreifuss muscular dystrophy
    Dale K Shumaker
    Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 102:15494-9. 2005
    ....