Darren R Gitelman

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Modeling regional and psychophysiologic interactions in fMRI: the importance of hemodynamic deconvolution
    Darren R Gitelman
    The Northwestern Cognitive Brain Mapping Group, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Neuroimage 19:200-7. 2003
  2. ncbi request reprint Language network specializations: an analysis with parallel task designs and functional magnetic resonance imaging
    Darren R Gitelman
    Cognitive Neurology and Alzheimer s Disease Center, Feinberg School of Medicine, Northwestern University, 3230 E Superior Street, Chicago, IL 60611, USA
    Neuroimage 26:975-85. 2005
  3. ncbi request reprint ILAB: a program for postexperimental eye movement analysis
    Darren R Gitelman
    Northwestern University Medical School, Chicago, Illinois 60611, USA
    Behav Res Methods Instrum Comput 34:605-12. 2002
  4. ncbi request reprint Altered effective connectivity within the language network in primary progressive aphasia
    Sreepadma P Sonty
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, Illinois 60611, USA
    J Neurosci 27:1334-45. 2007
  5. pmc Weaker top-down modulation from the left inferior frontal gyrus in children
    Tali Bitan
    Northwestern University, Evanston, Illinois 60208 3500, USA
    Neuroimage 33:991-8. 2006
  6. ncbi request reprint Relation between brain activation and lexical performance
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208, USA
    Hum Brain Mapp 19:155-69. 2003
  7. ncbi request reprint Larger deficits in brain networks for response inhibition than for visual selective attention in attention deficit hyperactivity disorder (ADHD)
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA
    J Child Psychol Psychiatry 46:94-111. 2005
  8. pmc Brain-behavior correlation in children depends on the neurocognitive network
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208, USA
    Hum Brain Mapp 23:99-108. 2004
  9. pmc EEG measures index neural and cognitive recovery from sleep deprivation
    Bryce A Mander
    Northwestern University Interdepartmental Neuroscience Program, and Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Neurosci 30:2686-93. 2010
  10. ncbi request reprint Neural development of selective attention and response inhibition
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA
    Neuroimage 20:737-51. 2003

Research Grants

Detail Information

Publications40

  1. ncbi request reprint Modeling regional and psychophysiologic interactions in fMRI: the importance of hemodynamic deconvolution
    Darren R Gitelman
    The Northwestern Cognitive Brain Mapping Group, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Neuroimage 19:200-7. 2003
    ..In this article, this assumption is revisited using estimates of underlying neuronal activity. These estimates use a parametric empirical Bayes formulation for hemodynamic deconvolution...
  2. ncbi request reprint Language network specializations: an analysis with parallel task designs and functional magnetic resonance imaging
    Darren R Gitelman
    Cognitive Neurology and Alzheimer s Disease Center, Feinberg School of Medicine, Northwestern University, 3230 E Superior Street, Chicago, IL 60611, USA
    Neuroimage 26:975-85. 2005
    ..Within the inferior frontal cortex (Broca's regional complex), segregated activations were seen for the semantic and phonological tasks. These findings demonstrate both common and task specific activations within the language system...
  3. ncbi request reprint ILAB: a program for postexperimental eye movement analysis
    Darren R Gitelman
    Northwestern University Medical School, Chicago, Illinois 60611, USA
    Behav Res Methods Instrum Comput 34:605-12. 2002
    ..The program consists of a series of open-source MATLAB functions. The program's data structures keep raw data, analysis preferences, and analyzed data separate, thus maintaining data fidelity and promoting extensibility...
  4. ncbi request reprint Altered effective connectivity within the language network in primary progressive aphasia
    Sreepadma P Sonty
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University, Chicago, Illinois 60611, USA
    J Neurosci 27:1334-45. 2007
    ..These results demonstrate for the first time that dysfunctional network interactions (effective connectivity), rather than hypoactivity within individual brain regions, may contribute to the emergence of language deficits seen in PPA...
  5. pmc Weaker top-down modulation from the left inferior frontal gyrus in children
    Tali Bitan
    Northwestern University, Evanston, Illinois 60208 3500, USA
    Neuroimage 33:991-8. 2006
    ..Adult language processing may thus involve greater top-down cognitive control compared to children, resulting in less interference from task-irrelevant information...
  6. ncbi request reprint Relation between brain activation and lexical performance
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208, USA
    Hum Brain Mapp 19:155-69. 2003
    ....
  7. ncbi request reprint Larger deficits in brain networks for response inhibition than for visual selective attention in attention deficit hyperactivity disorder (ADHD)
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA
    J Child Psychol Psychiatry 46:94-111. 2005
    ..Brain activation differences between 12 control and 12 attention deficit hyperactivity disorder (ADHD) children (9- to 12-year-olds) were examined on two cognitive tasks during functional magnetic resonance imaging (fMRI)...
  8. pmc Brain-behavior correlation in children depends on the neurocognitive network
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208, USA
    Hum Brain Mapp 23:99-108. 2004
    ..These results show that the relation of performance to the magnitude of neural activation is complex and may display differential relationships based on the cognitive domain, anatomical region, and perhaps also developmental stage...
  9. pmc EEG measures index neural and cognitive recovery from sleep deprivation
    Bryce A Mander
    Northwestern University Interdepartmental Neuroscience Program, and Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Neurosci 30:2686-93. 2010
    ..We thus propose that slow waves, reflected in delta power during RS, act to restore brain function, thereby improving cognitive performance that entails response inhibition...
  10. ncbi request reprint Neural development of selective attention and response inhibition
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL 60208, USA
    Neuroimage 20:737-51. 2003
    ..The extensive developmental differences on the response inhibition task are consistent with the prolonged maturation of the fronto-striatal network...
  11. pmc Shifts of effective connectivity within a language network during rhyming and spelling
    Tali Bitan
    Northwestern University, Evanston, Illinois 60208, USA
    J Neurosci 25:5397-403. 2005
    ....
  12. pmc Development of brain mechanisms for processing orthographic and phonologic representations
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, Evantson, Illinois, 60208, USA
    J Cogn Neurosci 16:1234-49. 2004
    ..The greater activation for adults suggests that they have more interactive convergence between representational systems during lexical processing...
  13. pmc Neural correlates of verb argument structure processing
    Cynthia K Thompson
    Department of Communication Disorders, Northwestern University, IL 60208, USA
    J Cogn Neurosci 19:1753-67. 2007
    ..These findings are consistent with processing accounts, which suggest that these regions are crucial for semantic integration...
  14. ncbi request reprint Functional anatomy of visual search: regional segregations within the frontal eye fields and effective connectivity of the superior colliculus
    Darren R Gitelman
    The Northwestern Cognitive Brain Mapping Group, Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Neuroimage 15:970-82. 2002
    ..In contrast to the existing literature on functional imaging, which has focused on covert shifts of spatial attention, this study helps to characterize the functional anatomy of overt spatial exploration...
  15. ncbi request reprint Modality independence of word comprehension
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois 60208 3560, USA
    Hum Brain Mapp 16:251-61. 2002
    ....
  16. ncbi request reprint Brain networks for analyzing eye gaze
    Christine I Hooker
    Department of Psychology, Northwestern University, 2029 Sheridan Road, Evanston, IL 60208 2710, USA
    Brain Res Cogn Brain Res 17:406-18. 2003
    ....
  17. ncbi request reprint The "zoom lens" of focal attention in visual search: changes in aging and Alzheimer's disease
    Alexander Rösler
    Cognitives Neurology and Alzheimer s Disease Center, Northwestern University Medical School, Chicago, IL, USA
    Cortex 41:512-9. 2005
    ..Reduced efficiency of visual search in AD may be contributed to by reduced ability to dynamically adjust the attentional zoom, coupled with the inability to disengage attention from peripheral targets...
  18. ncbi request reprint Priming effects in the fusiform gyrus: changes in neural activity beyond the second presentation
    Paul J Reber
    Department of Psychology, Northwestern University, 2029 Sheridan Road, Evanston, IL 60208, USA
    Cereb Cortex 15:787-95. 2005
    ..This region exhibits a pattern of activity consistent with a gradual and cumulative enhancement of the fluency effect across trials, suggesting that it may mediate the link between priming and the development of visual expertise...
  19. pmc Attention to odor modulates thalamocortical connectivity in the human brain
    Jane Plailly
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Neurosci 28:5257-67. 2008
    ..The results imply that olfaction, like all other sensory modalities, requires a thalamic relay, if only to consciously analyze a smell...
  20. pmc Neural correlates of person recognition
    Ken A Paller
    Department of Psychology, Northwestern University, Evanston, Illinois 60208, USA
    Learn Mem 10:253-60. 2003
    ....
  21. ncbi request reprint Neural evidence that vivid imagining can lead to false remembering
    Brian Gonsalves
    Department of Psychology, Northwestern University, Stanford, CA 94305, USA
    Psychol Sci 15:655-60. 2004
    ..These findings indicate that brain activity reflecting the engagement of visual imagery can lead to falsely remembering something that was only imagined...
  22. ncbi request reprint Functional anatomy of intra- and cross-modal lexical tasks
    James R Booth
    Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA
    Neuroimage 16:7-22. 2002
    ....
  23. pmc The spatial attention network interacts with limbic and monoaminergic systems to modulate motivation-induced attention shifts
    Aprajita Mohanty
    Cognitive Neurology and Alzheimer s Disease Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Cereb Cortex 18:2604-13. 2008
    ....
  24. ncbi request reprint Simultaneous assessment of motor and language areas with a single functional MR imaging paradigm: feasibility
    Todd A Mulderink
    Feinberg Neuroscience Institute and Department of Radiology, Feinberg School of Medicine, Northwestern University Medical School, 676 N St Clair St, Suite 1400, Chicago, IL 60611, USA
    Radiology 236:655-60. 2005
    ..Finally, the multitask design was tested in a patient undergoing preoperative evaluation, with similar results; therefore, use of the multitask design is feasible in a clinical setting...
  25. ncbi request reprint Neural correlates of sexual arousal in homosexual and heterosexual men
    Adam Safron
    Department of Psychology, Northwestern University, Evanston, IL 60208, USA
    Behav Neurosci 121:237-48. 2007
    ..Significant activational differences matched reported sexual orientation in 15 of these 16 participants, representing an advance in psychophysiological measures of arousal...
  26. ncbi request reprint Chronic back pain is associated with decreased prefrontal and thalamic gray matter density
    A Vania Apkarian
    Department of Physiology and Institute of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Neurosci 24:10410-5. 2004
    ..Our results imply that CBP is accompanied by brain atrophy and suggest that the pathophysiology of chronic pain includes thalamocortical processes...
  27. ncbi request reprint Neural correlates of successful encoding identified using functional magnetic resonance imaging
    Paul J Reber
    Department of Psychology, Northwestern University, Evanston, Illinois 60201, USA
    J Neurosci 22:9541-8. 2002
    ..Prefrontal activation was strongly associated with intentional verbal encoding, whereas left medial temporal activation was crucial for the encoding that actually led to successful memory on the subsequent test...
  28. pmc Sleep deprivation alters functioning within the neural network underlying the covert orienting of attention
    Bryce A Mander
    Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Brain Res 1217:148-56. 2008
    ..These changes may render sleep-deprived individuals less able to anticipate the locations of upcoming events, and more susceptible to distraction by stimuli at irrelevant locations...
  29. ncbi request reprint Primary progressive aphasia: PPA and the language network
    Sreepadma P Sonty
    Cognitive Neurology and Alzheimer s Disease Center, Chicago, IL, USA
    Ann Neurol 53:35-49. 2003
    ..The additional activations in PPA may therefore represent a compensatory spread of language-related neural activity or a failure to suppress activity in areas normally inhibited during language tasks...
  30. ncbi request reprint Cerebral hemispheric specialization for spatial attention: spatial distribution of search-related eye fixations in the absence of neglect
    Mark Mapstone
    Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Neuropsychologia 41:1396-409. 2003
    ..A theoretical model based on the salience of extrapersonal space appears useful for understanding alterations of attentional allocation, particularly after recovery from stroke...
  31. ncbi request reprint Vasectomy in men with primary progressive aphasia
    Sandra Weintraub
    Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Cogn Behav Neurol 19:190-3. 2006
    ..To study the frequency of vasectomy in men with primary progressive aphasia (PPA)...
  32. ncbi request reprint On the use of caffeine as a contrast booster for BOLD fMRI studies
    Todd A Mulderink
    Feinberg Neuroscience Institute, Northwestern Cognitive Brain Mapping Group, Department of Radiology, Northwestern University and Medical School, Chicago, Illinois 60611, USA
    Neuroimage 15:37-44. 2002
    ..Caffeine has the potential to be used as a contrast booster for fMRI experiments...
  33. ncbi request reprint Hemodynamic response changes in cerebrovascular disease: implications for functional MR imaging
    Leo M Carusone
    Feinberg Clinical Neuroscience Research Institute, Chicago, Illinois, USA
    AJNR Am J Neuroradiol 23:1222-8. 2002
    ..We investigated the BOLD signal in patients with unilateral cerebrovascular disease to ascertain the clinical utility of functional MR imaging in these patients...
  34. ncbi request reprint Attention and its disorders
    Darren R Gitelman
    Cognitive Neurology and Alzheimer s Disease Center, Department of Neurology, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Br Med Bull 65:21-34. 2003
    ..Imaging studies discussed are primarily functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). In addition, some evidence will be provided from the time-honoured clinical method of lesion studies...
  35. ncbi request reprint Orienting attention based on long-term memory experience
    Jennifer J Summerfield
    Brain and Cognition Laboratory, Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
    Neuron 49:905-16. 2006
    ..Activity in the hippocampus was specifically engaged in memory-guided spatial attention and correlated with the ensuing behavioral advantage...
  36. pmc Developmental changes in activation and effective connectivity in phonological processing
    Tali Bitan
    Department of Communication Disorders, Haifa University, Mt Carmel, 32905 Haifa, Israel
    Neuroimage 38:564-75. 2007
    ..Our results are consistent with the idea that there is reduced reliance on primary sensory processes as task-relevant processes mature and become more efficient during development...
  37. ncbi request reprint Effective connectivity and intersubject variability: using a multisubject network to test differences and commonalities
    Andrea Mechelli
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London, WCIN 3BG, United Kingdom
    Neuroimage 17:1459-69. 2002
    ..The discussion focuses on the implications of our findings and on further applications of the multisubject network analysis...
  38. doi request reprint Modulation of the spatial attention network by incentives in healthy aging and mild cognitive impairment
    Lisa A Bagurdes
    Cognitive Neurology and Alzheimer s Disease Center, Northwestern University Feinberg School of Medicine, United States
    Neuropsychologia 46:2943-8. 2008
    ..These results suggest a reorganization of the relationships between the limbic system and spatial attention network in healthy aging and MCI...
  39. ncbi request reprint Taste and olfactory intensity perception changes following left insular stroke
    Y Erica Mak
    The John B Pierce Laboratory, Yale University School of Medicine, New Haven, CT 06519, USA
    Behav Neurosci 119:1693-700. 2005
    ..These results show that a left posterior insula lesion may affect taste and olfactory perception similarly by increasing sensitivity contralateral to the lesion. One possible mechanism is release from inhibition at the cortical level...
  40. ncbi request reprint Dissociating explicit and implicit category knowledge with fMRI
    Paul J Reber
    Department of Psychology, Northwestern University, Evanston, IL 60201, USA preber northwestern edu
    J Cogn Neurosci 15:574-83. 2003
    ....

Research Grants1

  1. NEURAL NETWORK STABILITY AND VARIABILITY IN NORMAL AGING
    Darren Gitelman; Fiscal Year: 2003
    This is a request for an K-23 NIA Mentored Patient Oriented Research Career Award for Darren R Gitelman, MD under the mentorship of M-Marsel Mesulam, MD, Professor of Neurology and Psychiatry at Northwestern University...