Research Topics
| P GeramiSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
Fluorescence in situ hybridization as a diagnostic modality in melanocytic neoplasmaP Gerami
Dermatology, Pathology and Pediatrics, Northwestern University and The Feinberg School of Medicine
G Ital Dermatol Venereol 145:29-35. 2010....
Applying the new TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sézary syndrome in primary cutaneous marginal zone lymphomaPedram Gerami
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
J Am Acad Dermatol 59:245-54. 2008..However, few large series on this entity have been reported, including the new TNM (tumor, (lymph) node, metastasis) classification for non-mycosis fungoides cutaneous lymphomas...
Basaloid folliculolymphoid hyperplasia: a distinctive finding in follicular mycosis fungoidesPedram Gerami
Department of Dermatology, Northwestern University and Medical Center, The Feinberg School of Medicine, Chicago, IL 60611, USA
J Cutan Pathol 34:29-32. 2007..Hence, we describe the clinical-pathologic findings of basaloid folliculolymphoid hyperplasia in these three patients with follicular mycosis fungoides...
The spectrum of histopathologic and immunohistochemical findings in folliculotropic mycosis fungoidesPedram Gerami
Northwestern University and The Feinberg School of Medicine, Chicago, IL 60611, USA
Am J Surg Pathol 31:1430-8. 2007..However, there have been few large histologic studies characterizing the various histopathologic patterns...
Superficial melanocytic neoplasms with pagetoid melanocytosis: a study of interobserver concordance and correlation with FISHPedram Gerami
Department of Dermatology and the Lurie Cancer Center, The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Am J Surg Pathol 34:816-21. 2010..There is considerable discordance in superficial melanocytic neoplasm with prominent pagetoid melanocytosis even among expert consultants. There is likely a subset of such cases where FISH can play a significant role as a diagnostic aid...
Cutaneous involvement with marginal zone lymphomaPedram Gerami
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Am Acad Dermatol 63:142-5. 2010..Distinguishing primary cutaneous MZL (PCMZL) from secondary cutaneous MZL (SCMZL) is of utmost importance for prognostic and therapeutic approach...
Interleukins in the treatment of mycosis fungoidesP Gerami
Department of Dermatology, Northwestern University, Feinberg School of Medicine, Evanston, IL, USA
G Ital Dermatol Venereol 143:55-8. 2008..Lastly, they discuss other potential cytokine therapies which could play a role in the future treatment of mycosis fungoides...
Enhanced detection of spitzoid melanomas using fluorescence in situ hybridization with 9p21 as an adjunctive probeBryan Gammon
Department of Dermatology, Northwestern University School of Medicine, Chicago, IL, USA
Am J Surg Pathol 36:81-8. 2012..9p21 may be particularly helpful in lesions with spitzoid morphology...
Molecular analysis of a case of nevus of ota showing progressive evolution to melanoma with intermediate stages resembling cellular blue nevusPedram Gerami
Dermatology and daggerPathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Am J Dermatopathol 32:301-5. 2010..Copy number changes typical of melanoma were identified by both FISH and CGH in the morphologically malignant areas illustrating the relationship of tumor progression and the progressive acquisition of genetic aberrations...
Distinguishing epithelioid blue nevus from blue nevus-like cutaneous melanoma metastasis using fluorescence in situ hybridizationPedram Pouryazdanparast
Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Am J Surg Pathol 33:1396-400. 2009..The test and the parameters previously established can perform with high sensitivity and specificity when dealing with this differential diagnosis...
Follicular mycosis fungoides: a histopathologic, immunohistochemical, and genotypic reviewS L Boone
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
G Ital Dermatol Venereol 143:409-14. 2008..This review emphasizes and discusses the broad spectrum of histologic changes which may be seen in FMF, clues to the diagnosis, and some potential mimickers...
Fluorescence in situ hybridization as a tool for microstaging in malignant melanomaMarissa D Newman
Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Mod Pathol 22:989-95. 2009..The sensitivity is independent of the morphological features, and the assay performs well in nevoid melanoma cases...
Fluorescence in situ hybridization for distinguishing nevoid melanomas from mitotically active neviPedram Gerami
Northwestern University and the Feinberg School of Medicine and the Lurie Cancer Cancer, Chicago, IL 60611, USA
Am J Surg Pathol 33:1783-8. 2009..Additionally, our study presents further evidence that dermal mitoses alone without other diagnostic features such as nuclear atypia and lack of maturation does not constitute sufficient evidence alone for a diagnosis of melanoma...
Sensitivity of fluorescence in situ hybridization for melanoma diagnosis using RREB1, MYB, Cep6, and 11q13 probes in melanoma subtypesPedram Gerami
Department of Dermatology, Feinberg School of Medicine, Northwestern University, 676 N St Clair Street, Chicago, IL 60611, USA
Arch Dermatol 146:273-8. 2010..To evaluate the diagnostic sensitivity of fluorescence in situ hybridization (FISH) using probes targeting 6p25, 6q23, 11q13, and Cep6 in melanoma subtypes...
Two cases of multiple spitz nevi: correlating clinical, histologic, and fluorescence in situ hybridization findingsSusan L Boone
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Arch Dermatol 147:227-31. 2011..We describe 2 cases of patients with multiple Spitz nevi and their FISH results...
Fluorescence in situ hybridization for ambiguous melanocytic tumorsB Gammon
Northwestern University, Department of Dermatology, Chicago, IL 60611, USA
Histol Histopathol 27:1539-42. 2012..In this review, we discuss the current literature and studies to date on this topic...
Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanomaPedram Gerami
Department of Dermatology and the Lurie Cancer Center, Northwestern University, The Feinberg School of Medicine University of California, San Francisco, CA, USA
Am J Surg Pathol 33:1146-56. 2009..As a diagnostic aid to traditional histologic evaluation, this assay can have significant clinical impact and improve classification of melanocytic neoplasms with conflicting morphologic criteria...
Angiotropism in epidermotropic metastatic melanoma: another clue to the diagnosisPedram Gerami
Department of Dermatology, Northwestern University, Chicago, IL 60611, USA
Am J Dermatopathol 28:429-33. 2006..The differential diagnosis of locally recurrent melanoma with an epidermal component can be extremely challenging and the presence of angiotropism may be a clue to the diagnosis of EMMM...
Folliculotropic mycosis fungoides: an aggressive variant of cutaneous T-cell lymphomaPedram Gerami
Department of Dermatology, Northwestern University Feinberg School of Medicine, and the Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA
Arch Dermatol 144:738-46. 2008....
Alemtuzumab for relapsed and refractory erythrodermic cutaneous T-cell lymphoma: a single institution experience from the Robert H. Lurie Comprehensive Cancer CenterChristiane Querfeld
Section of Dermatology, University of Chicago, Chicago, IL, USA
Leuk Lymphoma 50:1969-76. 2009..Alemtuzumab is particularly effective in patients with erythrodermic CTCL with acceptable toxicities. Combined strategies with alemtuzumab may achieve molecular remissions with longer response durations...
Polyploidy in spitz nevi: a not uncommon karyotypic abnormality identifiable by fluorescence in situ hybridizationAnjeli Krishnan Isaac
Department of Dermatology, Northwestern University, Chicago, IL, USA
Am J Dermatopathol 32:144-8. 2010..The other case was from a 14-year-old man from the ankle. All 4 cases that were polyploid were confirmed using a probe for the X chromosome. This article highlights the importance of polyploidy as a feature of some benign Spitz nevi...
Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinibM E Lacouture
Department of Dermatology, SERIES Clinic, Northwestern University s Feinberg School of Medicine, Chicago, IL 60611, USA
Ann Oncol 19:1955-61. 2008..This study examined clinicopathological findings and management of hand foot skin reaction (HFSR) to sorafenib and sunitinib in a dermatology referral center for cancer-related toxic effects...
Cutaneous T-cell lymphoma and Staphylococcus aureus colonizationVictoria Nguyen
Department of Dermatology, Northwestern University, Chicago, Illinois 60611, USA
J Am Acad Dermatol 59:949-52. 2008..Bacterial infections are a common complication of cutaneous T-cell lymphoma (CTCL). The most common pathogen of cutaneous infections in CTCL patients is Staphylococcus aureus...
p63 in Primary Cutaneous CarcinosarcomaKi Young Suh
Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Am J Dermatopathol 29:374-7. 2007..In addition, the staining pattern of AE1/AE3 and p63 in these cases further supports the conversion theory of PCC...
Clinicopathologic challenge. Regional lymphomatoid papulosis, type AVishakha Sharma
Section of Dermatology, Department of Medicine, University of Chicago, Chicago, IL, USA
Int J Dermatol 46:905-9. 2007
The relationship between neutrophilic dermatosis of the dorsal hands and sweet syndrome: report of 9 cases and comparison to atypical pyoderma gangrenosumHobart W Walling
Department of Dermatology, University of Iowa, Iowa City, USA
Arch Dermatol 142:57-63. 2006..Its relationship to acute febrile neutrophilic dermatosis (Sweet syndrome), pyoderma gangrenosum, and a primary vasculitis has been debated...
Chromosomal copy number changes supporting the classification of lentiginous junctional melanoma of the elderly as a subtype of melanomaMarissa D Newman
Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Mod Pathol 22:1258-62. 2009..A total of 17 control cases of lentiginous junctional nevi tested negative for all criteria. These findings support the classification of this pattern of melanocytic neoplasia as a subtype of melanoma...
Oral mucosal MALT lymphoma clinically simulating oral facial granulomatosisPedram Gerami
Department of Dermatology, Northwest University, Chicago, IL 60611, USA
Int J Dermatol 46:868-71. 2007..Increased awareness and familiarity with oral mucosal MALT lymphoma and its clinical associations are of significant importance for optimal management of this condition...
A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis siné myositis): a missing link within the spectrum of the idiopathic inflammatory myopathiesPedram Gerami
Dermatopathology Division, University of Chicago, Chicago, Illinois, USA
J Am Acad Dermatol 54:597-613. 2006..This subphenotype, referred to as "pre-myopathic DM," is one with which dermatologists should be aware as early diagnosis and aggressive management can be lifesaving...
Touton-like giant cells in a Spitz's nevusJoan Guitart
J Cutan Pathol 35:694-5. 2008
Cyclin D1 homogeneous staining regions by fluorescent in situ hybridization: a possible indicator of aggressive behavior in melanomasPedram Gerami
Arch Dermatol 144:1235-6. 2008
Folliculotropic mycosis fungoides responding to bexarotene gelHobart W Walling
Town Square Dermatology, Coralville, IA 52241, USA
J Drugs Dermatol 7:169-71. 2008....
