Csaba GajdosSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
Relationship of clinical and pathologic response to neoadjuvant chemotherapy and outcome of locally advanced breast cancerCsaba Gajdos
Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
J Surg Oncol 80:4-11. 2002..Therefore, clinical or pathological factors, which predict or assess response to treatment, may predict outcome after consideration for initial extent of disease...
Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complexBin Chen
Robert H. Lurie Comprehensive Cancer Center, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Int J Oncol 27:327-35. 2005..We conclude that endogenous ERbeta may not play a dominant role in the modulation of the tamoxifen ERalpha complex, or in the development of tamoxifen-stimulated resistant tumor growth...
Reversal of tamoxifen resistant breast cancer by low dose estrogen therapyClodia Osipo
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
J Steroid Biochem Mol Biol 93:249-56. 2005..Based on the results, we suggest using an alternating treatment regimen, cycling antiestrogen with estrogen therapy to avoid drug-resistance...
Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancerClodia Osipo
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
J Natl Cancer Inst 95:1597-608. 2003..CONCLUSION: Physiologic levels of estradiol induced regression of tamoxifen-stimulated breast cancer tumors, apparently by inducing the death receptor Fas and suppressing the antiapoptotic/prosurvival factors NF-kappaB and HER2/neu...
Apoptotic action of 17beta-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivoHong Liu
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
J Natl Cancer Inst 95:1586-97. 2003....
A mechanism of drug resistance to tamoxifen in breast cancerJennifer MacGregor Schafer
Robert H. Lurie Comprehensive Cancer Center, The Feinberg School of Medicine, Northwestern University, Olson Pavilion 8258, 303 East Chicago Avenue, Chicago, IL 60611, USA
J Steroid Biochem Mol Biol 83:75-83. 2002..Three phases of tumor progression are described that involve increases in HER-2/neu expression, de-regulation of estrogen receptor expression and increases in apoptosis which in concert determine the phenotype of drug resistance to Tam...
Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decadeCsaba Gajdos
Robert H. Lurie Comprehensive Cancer Center, Northwestern University Medical School, 303 E. Chicago Avenue, Chicago, IL 60611, USA
Clin Breast Cancer 2:272-81. 2002....
Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic miceCsaba Gajdos
Division of Hematology/Oncology, Northwestern University, Chicago, IL 60611, USA
J Natl Cancer Inst 94:274-83. 2002..Treatment with raloxifene following 5 years of adjuvant tamoxifen may not further decrease breast cancer recurrence and may increase endometrial cancer incidence...
The prognostic significance of Gail model risk factors for women with breast cancerPaul Ian Tartter
Department of Surgery, St Luke s Roosevelt Hospital Center, New York, NY, USA
Am J Surg 184:11-5. 2002..In order to assess the prognostic value of risk factors for breast cancer we divided patients with breast cancer into those at high risk and low risk using the Gail model...
Mammographic appearance of nonpalpable breast cancer reflects pathologic characteristicsCsaba Gajdos
Department of Surgery, The Mount Sinai Medical Center, New York, New York, USA
Ann Surg 235:246-51. 2002..The mammographic appearance of nonpalpable malignancies is related to pathologic characteristics with prognostic value, which varies with patient age and influences clinical management...
