Leon G Epstein

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. pmc Human herpesvirus 6 and 7 in febrile status epilepticus: the FEBSTAT study
    Leon G Epstein
    Department of Pediatrics, Feinberg School of Medicine, Northwestern University and Ann and Robert H Lurie Children s Hospital of Chicago, Chicago, Illinois, USA
    Epilepsia 53:1481-8. 2012
  2. pmc Cerebrospinal fluid findings in children with fever-associated status epilepticus: results of the consequences of prolonged febrile seizures (FEBSTAT) study
    L Matthew Frank
    Department of Pediatrics, Children s Hospital of The King s Daughters and Eastern Virginia Medical School, Norfolk, VA, USA
    J Pediatr 161:1169-71. 2012
  3. pmc Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
    J Neurovirol 11:292-8. 2005
  4. pmc Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, Illinois 60611 2927, USA
    J Neurovirol 15:275-81. 2009
  5. pmc Biomarkers of neurological status in HIV infection: a 3-year study
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    Proteomics Clin Appl 4:295-303. 2010
  6. pmc Marked relationship between matrix metalloproteinase 7 and brain atrophy in HIV infection
    Ann B Ragin
    Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611 2927, USA
    J Neurovirol 17:153-8. 2011
  7. pmc Whole brain diffusion tensor imaging in HIV-associated cognitive impairment
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    AJNR Am J Neuroradiol 25:195-200. 2004
  8. ncbi request reprint Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy
    Justin C McArthur
    Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 7609, USA
    Arch Neurol 61:1687-96. 2004
  9. ncbi request reprint An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection
    Jeffrey J Sevigny
    Department of Neurology and Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Arch Neurol 64:97-102. 2007

Research Grants

Collaborators

Detail Information

Publications9

  1. pmc Human herpesvirus 6 and 7 in febrile status epilepticus: the FEBSTAT study
    Leon G Epstein
    Department of Pediatrics, Feinberg School of Medicine, Northwestern University and Ann and Robert H Lurie Children s Hospital of Chicago, Chicago, Illinois, USA
    Epilepsia 53:1481-8. 2012
    ..In a prospective study, Consequences of Prolonged Febrile Seizures in Childhood (FEBSTAT), we determined the frequency of human herpesvirus (HHV)-6 and HHV-7 infection as a cause of febrile status epilepticus (FSE)...
  2. pmc Cerebrospinal fluid findings in children with fever-associated status epilepticus: results of the consequences of prolonged febrile seizures (FEBSTAT) study
    L Matthew Frank
    Department of Pediatrics, Children s Hospital of The King s Daughters and Eastern Virginia Medical School, Norfolk, VA, USA
    J Pediatr 161:1169-71. 2012
    ..CSF glucose and protein levels were unremarkable. Temperature, age, seizure focality, and seizure duration did not affect results. CSF pleocytosis should not be attributed to FSE...
  3. pmc Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
    J Neurovirol 11:292-8. 2005
    ..Findings from this investigation indicate that DTI is a sensitive tool for correlating neuroanatomic pathologic features with specific cognitive deficits in patients with HIV infection...
  4. pmc Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, Illinois 60611 2927, USA
    J Neurovirol 15:275-81. 2009
    ..MMPs may influence neurological outcome through involvement in neuroimmune response, blood-brain barrier permeability, leukocyte migration, and MMP-mediated neurotoxicity...
  5. pmc Biomarkers of neurological status in HIV infection: a 3-year study
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    Proteomics Clin Appl 4:295-303. 2010
    ..To evaluate circulating cytokines and chemokines as correlates of the degree of brain injury in individuals with advanced human immunodeficiency virus (HIV) infection...
  6. pmc Marked relationship between matrix metalloproteinase 7 and brain atrophy in HIV infection
    Ann B Ragin
    Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611 2927, USA
    J Neurovirol 17:153-8. 2011
    ..MMP-7 was also correlated with measures of virologic and cognitive status...
  7. pmc Whole brain diffusion tensor imaging in HIV-associated cognitive impairment
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    AJNR Am J Neuroradiol 25:195-200. 2004
    ..This investigation evaluated the prognostic significance of whole brain histogram-derived diffusion tensor imaging indices with respect to severity of cognitive impairment and measures of clinical status in cases of HIV...
  8. ncbi request reprint Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy
    Justin C McArthur
    Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 7609, USA
    Arch Neurol 61:1687-96. 2004
    ..Before the introduction of combination antiretroviral therapy (CART), neurological disease correlated with cerebrospinal fluid (CSF) levels of human immunodeficiency virus (HIV) RNA...
  9. ncbi request reprint An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection
    Jeffrey J Sevigny
    Department of Neurology and Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Arch Neurol 64:97-102. 2007
    ..Several markers of immune activation have been identified as potential prognostic markers for human immunodeficiency virus (HIV)-associated morbidity and mortality, but the results from studies are conflicting...

Research Grants1

  1. NEUROCOGNITIVE FUNCTION, HIV LOAD AND SURROGATE MARKERS
    Leon Epstein; Fiscal Year: 2003
    ..This diverse cohort of subjects with advanced HIV infection provides a unique opportunity to investigate the relationship between virus load, immune activation and the progression of neurologic dysfunction during HIV infection. ..