J Ludovic Croxford

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. ncbi request reprint Therapeutic potential of cannabinoids in CNS disease
    J Ludovic Croxford
    Department of Microbiology Immunology, Northwestern University Medical School, Chicago, Illinois 60610, USA
    CNS Drugs 17:179-202. 2003
  2. ncbi request reprint Structural requirements for initiation of cross-reactivity and CNS autoimmunity with a PLP139-151 mimic peptide derived from murine hepatitis virus
    J Ludovic Croxford
    Department of Microbiology Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Eur J Immunol 36:2671-80. 2006
  3. pmc Initiation and exacerbation of autoimmune demyelination of the central nervous system via virus-induced molecular mimicry: implications for the pathogenesis of multiple sclerosis
    J Ludovic Croxford
    Department of Microbiology and Immunology and Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Chicago, Illinois 60611, USA
    J Virol 79:8581-90. 2005
  4. ncbi request reprint Effects of cannabinoid treatment on Chagas disease pathogenesis: balancing inhibition of parasite invasion and immunosuppression
    J Ludovic Croxford
    Department of Microbiology Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Cell Microbiol 7:1592-602. 2005
  5. ncbi request reprint Towards cannabis and cannabinoid treatment of multiple sclerosis
    J Ludovic Croxford
    Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Drugs Today (Barc) 40:663-76. 2004
  6. ncbi request reprint Viral delivery of an epitope from Haemophilus influenzae induces central nervous system autoimmune disease by molecular mimicry
    J Ludovic Croxford
    Department of Microbiology Immunology, and Interdepartmental Immunobiology Center, Northwestern University Medical School, Chicago, IL 60611, USA
    J Immunol 174:907-17. 2005
  7. ncbi request reprint Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
    Gareth Pryce
    Department of Neuroinflammation, Institute of Neurology, University College London, London, UK
    Brain 126:2191-202. 2003
  8. ncbi request reprint Cannabinoids and the immune system: potential for the treatment of inflammatory diseases?
    J Ludovic Croxford
    Department of Immunology, National Institute of Neuroscience, NCNP, 4 1 1 Ogawahigashi, Kodaira, Tokyo 187 8502, Japan
    J Neuroimmunol 166:3-18. 2005
  9. ncbi request reprint Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis
    J Ludovic Croxford
    Department of Neuroinflammation, Institute of Neurology, University College London, London WC1N 1PJ, United Kingdom
    J Neuroimmunol 193:120-9. 2008

Detail Information

Publications9

  1. ncbi request reprint Therapeutic potential of cannabinoids in CNS disease
    J Ludovic Croxford
    Department of Microbiology Immunology, Northwestern University Medical School, Chicago, Illinois 60610, USA
    CNS Drugs 17:179-202. 2003
    ..Where applicable, reference is made to ongoing clinical trials of cannabinoids to alleviate symptoms of these disorders...
  2. ncbi request reprint Structural requirements for initiation of cross-reactivity and CNS autoimmunity with a PLP139-151 mimic peptide derived from murine hepatitis virus
    J Ludovic Croxford
    Department of Microbiology Immunology and the Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Eur J Immunol 36:2671-80. 2006
    ..This study describes a structural requirement for potential PLP139-151 mimic peptides, and provides further evidence for infection-induced molecular mimicry in the pathogenesis of autoimmune disease...
  3. pmc Initiation and exacerbation of autoimmune demyelination of the central nervous system via virus-induced molecular mimicry: implications for the pathogenesis of multiple sclerosis
    J Ludovic Croxford
    Department of Microbiology and Immunology and Interdepartmental Immunobiology Center, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Chicago, Illinois 60611, USA
    J Virol 79:8581-90. 2005
    ..Collectively, these findings illustrate the evolving mechanisms by which virus infections may contribute to both the initiation and exacerbation of autoimmune diseases, and they have important implications for MS pathogenesis...
  4. ncbi request reprint Effects of cannabinoid treatment on Chagas disease pathogenesis: balancing inhibition of parasite invasion and immunosuppression
    J Ludovic Croxford
    Department of Microbiology Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Cell Microbiol 7:1592-602. 2005
    ..Refined use of cannabinoids may prove therapeutic in the future, but our results raise concern about the effect of cannabis use on those chronically infected by T. cruzi and on heart cell homeostasis generally...
  5. ncbi request reprint Towards cannabis and cannabinoid treatment of multiple sclerosis
    J Ludovic Croxford
    Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Drugs Today (Barc) 40:663-76. 2004
    ....
  6. ncbi request reprint Viral delivery of an epitope from Haemophilus influenzae induces central nervous system autoimmune disease by molecular mimicry
    J Ludovic Croxford
    Department of Microbiology Immunology, and Interdepartmental Immunobiology Center, Northwestern University Medical School, Chicago, IL 60611, USA
    J Immunol 174:907-17. 2005
    ..These results have important implications for explaining the pathogenesis of MS and other autoimmune diseases...
  7. ncbi request reprint Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
    Gareth Pryce
    Department of Neuroinflammation, Institute of Neurology, University College London, London, UK
    Brain 126:2191-202. 2003
    ..Therefore, in addition to symptom management, cannabis may also slow the neurodegenerative processes that ultimately lead to chronic disability in multiple sclerosis and probably other diseases...
  8. ncbi request reprint Cannabinoids and the immune system: potential for the treatment of inflammatory diseases?
    J Ludovic Croxford
    Department of Immunology, National Institute of Neuroscience, NCNP, 4 1 1 Ogawahigashi, Kodaira, Tokyo 187 8502, Japan
    J Neuroimmunol 166:3-18. 2005
    ..This review article will highlight recent research on cannabinoids and how they interact with the immune system and also their potential use as therapeutic agents for a number of inflammatory disorders...
  9. ncbi request reprint Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis
    J Ludovic Croxford
    Department of Neuroinflammation, Institute of Neurology, University College London, London WC1N 1PJ, United Kingdom
    J Neuroimmunol 193:120-9. 2008
    ..This further highlights the neuroprotective potential of cannabinoids to slow the progression of MS...