Laura A Colangelo

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..Clinical trials assessing the effects of T replacement therapy on depressive symptoms in hypogonadal men should consider including CAG RL in their design and/or analysis...

..To assess associations of sex hormones with impaired fasting glucose (IFG) and type 2 diabetes in men...

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..However, most human studies have not controlled adequately for confounding factors, particularly nutritional intake. This population-based study examined whether CRP is inversely associated with IGF-I and IGFBP-3 concentrations...

..Importantly, they suggest that IGF-I and/or IGFBP-3 levels could be influenced by changes in BMI, and perhaps by physical activity, alcohol intake, and cigarette smoking...

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..In conclusion, the associations of dietary factors with serum IGF-1 and IGFBP-3 observed in our study corroborate those from other studies and generally do not differ between black and white men...

..05), respectively. These findings do not support a strong link between IGF-1 and IGFBP-3 and blood pressure, but they do support the possibility of important relations between IGFBP-3 and lipid levels in young adult men...

..Diastolic dysfunction in young adults is associated with increased morbidity and mortality, and the identification of prospective risk markers associated with diastolic dysfunction could allow for targeted primary prevention efforts...

..These results support the need for further research investigating the effect of physical activity on breast cancer risk...

..We examined whether adopting a healthy lifestyle throughout young adulthood is associated with the presence of the low cardiovascular disease risk profile in middle age...

..Data are sparse regarding the association of stable body mass index (BMI) over the long term with metabolic syndrome components in young adults...

..Whether systemic inflammation in healthy young adults is associated with future impairment in lung health is uncertain...

..87-7.12), and was 1.87 for men and women combined (95% CI, 1.08-3.22). CONCLUSIONS: The results of the current study support an association between cigarette smoking and CRC mortality, particularly in women age < 50 years...

..ST elevation in precordial leads has been associated with genetic syndromes of arrhythmias and sudden death. ST height data in different ethnic groups are limited...

..We examined the associations of serum testosterone and sex hormone binding globulin (SHBG) concentrations with physical activity and cardiorespiratory fitness in black and white young men...

..Additional research focusing on relationships of other, potentially modifiable, factors with the extent of breast density is warranted to better understand the interindividual variability in density among Hispanic women...

..37). For men and women combined, the RR was 1.50 (95% CI, 1.03-2.19). These findings provide evidence for a modest association of PLG and insulin resistance syndrome with colorectal cancer mortality and support the insulin hypothesis...

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..Therefore, we derived gender-based normative values for echocardiographic measurements of RVED area, in a large bi-racial cohort of young adults...

..To determine in a prospective cohort of generally healthy young adults the influence of early adult lung function on the presence of airflow obstruction in middle age...

..There was no relation between D327N genotype and SHBG levels. These results suggest that the (TAAAA)(n) repeat length in the SHBG gene, but not the D327N variant, might contribute to the interindividual variability in serum SHBG levels...

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..CONCLUSIONS: In a generally healthy young adult cohort, LV structure as defined by LV mass and geometry is associated with SBP and BMI at levels generally considered normal...