B A Cohen

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint Opportunistic infections of the central nervous system in the transplant patient
    Bruce A Cohen
    Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Curr Neurol Neurosci Rep 13:376. 2013
  2. ncbi request reprint Identifying and treating patients with suboptimal responses
    B A Cohen
    Davee Department of Neurology, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, Illinois 60611, USA
    Neurology 63:S33-40. 2004
  3. ncbi request reprint Chronic meningitis
    Bruce A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Curr Neurol Neurosci Rep 5:429-39. 2005
  4. ncbi request reprint Emerging oral therapies for multiple sclerosis
    B A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Clin Pract 61:1922-30. 2007
  5. doi request reprint The implications of immunogenicity for protein-based multiple sclerosis therapies
    Bruce A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago IL 60611, USA
    J Neurol Sci 275:7-17. 2008
  6. ncbi request reprint Clinical applications of new cerebrospinal fluid analytic techniques for the diagnosis and treatment of central nervous system infections
    B A Cohen
    Department of Neurology, Northwestern University Medical School, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Curr Neurol Neurosci Rep 1:518-25. 2001
  7. doi request reprint Identification, causation, alleviation, and prevention of complications (ICAP): an approach to symptom and disability management in multiple sclerosis
    Bruce A Cohen
    Northwestern University, Department of Neurology, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Neurology 71:S14-20. 2008
  8. doi request reprint PRISMS: the story of a pivotal clinical trial series in multiple sclerosis
    Bruce A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Curr Med Res Opin 26:827-38. 2010
  9. ncbi request reprint Mitoxantrone treatment of multiple sclerosis: safety considerations
    Bruce A Cohen
    Davee Department of Neurology, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, Illinois 60611, USA
    Neurology 63:S28-32. 2004
  10. ncbi request reprint A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection. AIDS Clinical Trials Group Team 291
    J C McArthur
    Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    Neurology 54:1080-8. 2000

Collaborators

Detail Information

Publications28

  1. doi request reprint Opportunistic infections of the central nervous system in the transplant patient
    Bruce A Cohen
    Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Curr Neurol Neurosci Rep 13:376. 2013
    ..Here, we review major opportunistic pathogens of the CNS seen in transplant patients, highlighting distinguishing epidemiologic and clinical features. ..
  2. ncbi request reprint Identifying and treating patients with suboptimal responses
    B A Cohen
    Davee Department of Neurology, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, Illinois 60611, USA
    Neurology 63:S33-40. 2004
    ..The panel then considered the use of mitoxantrone for patients with worsening MS and a suboptimal response to DMA therapy...
  3. ncbi request reprint Chronic meningitis
    Bruce A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Curr Neurol Neurosci Rep 5:429-39. 2005
    ..This review discusses selected etiologies illustrating issues in diagnosis and etiologic categories to be considered in the evaluation of this challenging syndrome...
  4. ncbi request reprint Emerging oral therapies for multiple sclerosis
    B A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Clin Pract 61:1922-30. 2007
    ..Therefore, alternative MS treatments with less invasive routes of administration and new modes of action are needed to expand the current treatment repertoire, increase patient satisfaction and adherence, and thereby improve efficacy...
  5. doi request reprint The implications of immunogenicity for protein-based multiple sclerosis therapies
    Bruce A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago IL 60611, USA
    J Neurol Sci 275:7-17. 2008
    ..Experience with generic biosimilars of other protein therapeutics suggests that the immunogenicity of generic biosimilar agents cannot be assumed and must be established for each formulation...
  6. ncbi request reprint Clinical applications of new cerebrospinal fluid analytic techniques for the diagnosis and treatment of central nervous system infections
    B A Cohen
    Department of Neurology, Northwestern University Medical School, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Curr Neurol Neurosci Rep 1:518-25. 2001
    ..Some of these applications are commonly available, whereas others are likely to enter the physician's armamentarium in the near future. As they do, they can be expected to improve the treatment of CNS infections...
  7. doi request reprint Identification, causation, alleviation, and prevention of complications (ICAP): an approach to symptom and disability management in multiple sclerosis
    Bruce A Cohen
    Northwestern University, Department of Neurology, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, IL 60611, USA
    Neurology 71:S14-20. 2008
    ..This article describes the application of an organizational scheme of identification, causation, alleviation, and prevention of complications as a tool for identifying and managing symptomatic issues in patients with MS...
  8. doi request reprint PRISMS: the story of a pivotal clinical trial series in multiple sclerosis
    Bruce A Cohen
    Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Curr Med Res Opin 26:827-38. 2010
    ..This review is the first collation of all these data in one article, with a look ahead to the next generation of studies involving the new formulation of sc IFN beta-1a...
  9. ncbi request reprint Mitoxantrone treatment of multiple sclerosis: safety considerations
    Bruce A Cohen
    Davee Department of Neurology, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1121, Chicago, Illinois 60611, USA
    Neurology 63:S28-32. 2004
    ..Careful laboratory and cardiac monitoring can reduce the possibility of adverse events and enhance patient safety...
  10. ncbi request reprint A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection. AIDS Clinical Trials Group Team 291
    J C McArthur
    Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    Neurology 54:1080-8. 2000
    ..To evaluate the safety and efficacy of recombinant human nerve growth factor (rhNGF) in HIV-associated sensory neuropathy (SN) within a multicenter, placebo-controlled, randomized trial (ACTG 291)...
  11. pmc Monocyte chemoattractant protein-1 correlates with subcortical brain injury in HIV infection
    A B Ragin
    Department of Radiology, The Children s Memorial Research Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 66:1255-7. 2006
    ..MCP-1 levels correlated with tissue status (mean diffusivity) in all examined regions. Plasma markers were also significantly correlated with anisotropy measurements in centrum semiovale (TNF-alpha) and putamen (hematocrit)...
  12. pmc Bone marrow diffusion measures correlate with dementia severity in HIV patients
    A B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    AJNR Am J Neuroradiol 27:589-92. 2006
    ..This study tested the hypothesis that the mean diffusivity is sensitive to marrow changes in HIV patients and that these quantitative imaging measurements correlate with the severity of dementia...
  13. pmc Diffusion alterations in corpus callosum of patients with HIV
    Y Wu
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    AJNR Am J Neuroradiol 27:656-60. 2006
    ....
  14. pmc Whole brain and localized magnetization transfer measurements are associated with cognitive impairment in patients infected with human immunodeficiency virus
    Y Wu
    Department of Radiology, Evanston Northwestern Healthcare, Evanston, Ill, USA
    AJNR Am J Neuroradiol 29:140-5. 2008
    ..This study investigated the utility of magnetization transfer (MT) imaging for quantification of brain tissue alterations associated with cognitive deficits in patients with HIV...
  15. pmc Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
    J Neurovirol 11:292-8. 2005
    ..Findings from this investigation indicate that DTI is a sensitive tool for correlating neuroanatomic pathologic features with specific cognitive deficits in patients with HIV infection...
  16. pmc Biomarkers of neurological status in HIV infection: a 3-year study
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    Proteomics Clin Appl 4:295-303. 2010
    ..To evaluate circulating cytokines and chemokines as correlates of the degree of brain injury in individuals with advanced human immunodeficiency virus (HIV) infection...
  17. ncbi request reprint Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases: the evolution from myeloablative to lymphoablative transplant regimens
    Richard K Burt
    Northwestern University Feinberg School of Medicine, Chicago, Illinois 60011, USA
    Arthritis Rheum 54:3750-60. 2006
  18. ncbi request reprint Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores
    Richard K Burt
    Department of Neurology, Northwestern University Medical School, Chicago, IL, USA
    Blood 102:2373-8. 2003
    ..Specifically, more patients and longer follow-up would be required in patients with an EDSS of 6.0 or less before drawing conclusions on this subgroup...
  19. pmc Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection
    Ann B Ragin
    Department of Radiology, Northwestern University, Chicago, Illinois 60611 2927, USA
    J Neurovirol 15:275-81. 2009
    ..MMPs may influence neurological outcome through involvement in neuroimmune response, blood-brain barrier permeability, leukocyte migration, and MMP-mediated neurotoxicity...
  20. pmc Minocycline treatment for HIV-associated cognitive impairment: results from a randomized trial
    N Sacktor
    Department of Neurology, Johns Hopkins Bayview Medical Center, 4940 Eastern Ave, 301 Building, Suite 2100, Baltimore, MD 21224, USA
    Neurology 77:1135-42. 2011
    ..We conducted a study of minocycline to assess its safety, tolerability, and efficacy for the treatment of HIV-associated cognitive impairment...
  21. pmc Disease burden in HIV-associated cognitive impairment: a study of whole-brain imaging measures
    A B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Neurology 63:2293-7. 2004
    ....
  22. ncbi request reprint Long-term treatment with recombinant nerve growth factor for HIV-associated sensory neuropathy
    G Schifitto
    Department of Neurology, University of Rochester, NY 14642, USA
    Neurology 57:1313-6. 2001
    ..However, there was no improvement of neuropathy severity as assessed by neurologic examination, quantitative sensory testing, and epidermal nerve fiber density...
  23. ncbi request reprint A randomized clinical trial of CPI-1189 for HIV-associated cognitive-motor impairment
    D B Clifford
    Department of Neurology, Washington University, St Louis, MO 63110, USA
    Neurology 59:1568-73. 2002
    ..It has neuroprotective properties in model systems for HIV-associated neurotoxicity and thus is a candidate for neuroprotective therapy in humans with HIV-associated CNS disease...
  24. pmc Whole brain diffusion tensor imaging in HIV-associated cognitive impairment
    Ann B Ragin
    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    AJNR Am J Neuroradiol 25:195-200. 2004
    ..This investigation evaluated the prognostic significance of whole brain histogram-derived diffusion tensor imaging indices with respect to severity of cognitive impairment and measures of clinical status in cases of HIV...
  25. ncbi request reprint Reduced intraepidermal nerve fiber density in HIV-associated sensory neuropathy
    M Polydefkis
    Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    Neurology 58:115-9. 2002
    ..To explore the relationship between intraepidermal nerve fiber (IENF) density in HIV-associated sensory neuropathy (HIV-SN) to measurements of neuropathy severity and progression of HIV disease...
  26. pmc The generalizability of neurocognitive test/retest data derived from a nonclinical sample for detecting change among two HIV+ cohorts
    Andrew J Levine
    Department of Neurology, National Neurological AIDS Bank, UCLA David Geffen School of Medicine, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 29:669-78. 2007
    ..Thus, the accuracy of the two methods examined for determining clinically significant change among HIV+ cohorts differs depending upon their similarity with the normative sample...
  27. ncbi request reprint A pilot study of cidofovir for progressive multifocal leukoencephalopathy in AIDS
    Christina M Marra
    Department of Neurology and Medicine, University of Washington School of Medicine, Seattle, WA, USA
    AIDS 16:1791-7. 2002
    ..To assess the safety, tolerability and effect of cidofovir for HIV-1 associated progressive multifocal leukoencephalopathy...
  28. ncbi request reprint Psychosocial risk factors of HIV morbidity and mortality: findings from the Multicenter AIDS Cohort Study (MACS)
    Roxanna Farinpour
    UCLA Neuropsychiatric Institute, Los Angeles, CA 90095, USA
    J Clin Exp Neuropsychol 25:654-70. 2003
    ....