Research Topics
Species | A ChlenskiSummaryAffiliation: Northwestern University Country: USA Publications
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Detail Information
Publications
Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissuesA Chlenski
Department of Pathology and the Robert H Lurie Cancer Center, Northwestern University Medical School, Chicago, IL 60611, USA
Biochim Biophys Acta 1493:319-24. 2000..Thus, our data indicate the importance of zo-2 (tjp-2) gene regulation in ductal cancer development and should help to understand the defects of intercellular interactions, critical for suppressing the malignant phenotype...
Androgen receptor expression in androgen-independent prostate cancer cell linesA Chlenski
Department of Pathology and the Robert H Lurie Cancer Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
Prostate 47:66-75. 2001..We attempted to clarify the mechanism(s) responsible for the failure to respond to androgen...
zo-2 gene alternative promoters in normal and neoplastic human pancreatic duct cellsA Chlenski
Department of Pathology, Northwestern University Medical School, Chicago, IL, USA
Int J Cancer 83:349-58. 1999..Methylation of P(A) is responsible for the inactivation of the suppressed promoter at the late stages of tumor development...
Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinomaA Chlenski
Department of Pathology and the Robert H Lurie Cancer Center, Northwestern University Medical School, Chicago, IL 60611, USA
Int J Cancer 82:137-44. 1999..This suggests the presence of a yet to be identified motif important for cell-growth regulation within the 23-amino acid residue N-terminal peptide of ZO-2A, MPVRGDRGFPPRRELSGWLRAPG...
Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cellsK I Nakashiro
Department of Pathology, Northwestern University Medical School, Chicago, Illinois, USA
Am J Pathol 159:591-7. 2001..Failure to express PPARgamma or ineffective transcriptional activity may be some of the mechanisms responsible for resistance to the inhibitory action of PPARgamma ligands...
Analysis of the kinase-related protein gene found at human chromosome 3q21 in a multi-gene cluster: organization, expression, alternative splicing, and polymorphic markerD M Watterson
Department of Molecular Pharmacology and Biological Chemistry, Northwestern University, Chicago, Illinois, USA
J Cell Biochem 75:481-91. 1999....
SPARC enhances tumor stroma formation and prevents fibroblast activationA Chlenski
The Robert H Lurie Comprehensive Cancer Center, Chicago, IL, USA
Oncogene 26:4513-22. 2007..Taken together, our results suggest that in addition to blocking angiogenesis, SPARC may inhibit tumor growth by promoting the assembly of stroma that is non-permissive for tumor progression...
