JASON BRICKNER

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint Transcriptional memory: staying in the loop
    Jason H Brickner
    Department of Biochemistry, Molecular Biology and Cell Biology, Hogan 2100, 2205 Tech Drive, Northwestern University, Evanston, IL 60201, USA
    Curr Biol 20:R20-1. 2010
  2. pmc DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery
    Sara Ahmed
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208, USA
    Nat Cell Biol 12:111-8. 2010
  3. pmc Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle
    Donna Garvey Brickner
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208, USA
    Mol Biol Cell 21:3421-32. 2010
  4. pmc A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory
    William H Light
    Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America
    PLoS Biol 11:e1001524. 2013
  5. pmc Interchromosomal clustering of active genes at the nuclear pore complex
    Donna G Brickner
    Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA
    Nucleus 3:487-92. 2012
  6. pmc Transcriptional memory at the nuclear periphery
    Jason H Brickner
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL, USA
    Curr Opin Cell Biol 21:127-33. 2009
  7. pmc Nuclear architecture: the cell biology of a laminopathy
    Jason H Brickner
    Department of Molecular Biosciences, Northwestern University, Hogan 2100, Evanston, IL 60201, USA
    Curr Biol 21:R807-9. 2011

Research Grants

Collaborators

  • William H Light
  • Donna G Brickner
  • Sara Ahmed
  • Donna Garvey Brickner
  • Agustina D'Urso
  • Jonathan Freaney
  • Varun Sood
  • Abbey Thompson
  • Curt M Horvath
  • Tom Volpe
  • Alexander B Froyshteter
  • Ivelisse Cajigas
  • Michele McDonough

Detail Information

Publications7

  1. doi request reprint Transcriptional memory: staying in the loop
    Jason H Brickner
    Department of Biochemistry, Molecular Biology and Cell Biology, Hogan 2100, 2205 Tech Drive, Northwestern University, Evanston, IL 60201, USA
    Curr Biol 20:R20-1. 2010
    ..Two new papers show that gene looping can persist after genes are repressed, promoting rapid reactivation of transcription, a phenomenon known as transcriptional memory...
  2. pmc DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery
    Sara Ahmed
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208, USA
    Nat Cell Biol 12:111-8. 2010
    ..Finally, GRS I also functions as a DNA zip code in Schizosaccharomyces pombe, suggesting that this mechanism of targeting to the nuclear periphery has been conserved over approximately one billion years of evolution...
  3. pmc Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle
    Donna Garvey Brickner
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208, USA
    Mol Biol Cell 21:3421-32. 2010
    ..Thus, phosphorylation of a nuclear pore component by cyclin dependent kinase controls the localization of active genes to the nuclear periphery through the cell cycle...
  4. pmc A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory
    William H Light
    Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America
    PLoS Biol 11:e1001524. 2013
    ..These results suggest that Nup100/Nup98 binding to recently expressed promoters plays a conserved role in promoting epigenetic transcriptional memory...
  5. pmc Interchromosomal clustering of active genes at the nuclear pore complex
    Donna G Brickner
    Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA
    Nucleus 3:487-92. 2012
    ..We speculate that our findings might provide insight into other types of gene kissing, some of which also require cis-acting DNA sequences and trans-acting proteins...
  6. pmc Transcriptional memory at the nuclear periphery
    Jason H Brickner
    Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL, USA
    Curr Opin Cell Biol 21:127-33. 2009
    ..Z and the Gal1 protein itself. Here, I review what we have learned about this type of transcriptional memory in yeast, what remains to be resolved and the challenges associated with understanding such epigenetic phenomena...
  7. pmc Nuclear architecture: the cell biology of a laminopathy
    Jason H Brickner
    Department of Molecular Biosciences, Northwestern University, Hogan 2100, Evanston, IL 60201, USA
    Curr Biol 21:R807-9. 2011
    ..A new study shows that lamin mutant worms display muscle-specific defects linked to altered subnuclear localization of heterochromatin, leading to altered gene expression...

Research Grants5

  1. Role of DNA localization in regulating transcription
    JASON BRICKNER; Fiscal Year: 2009
    ..2004). Understanding the role of DMA localization in controlling gene expression may illuminate the cellular and molecular defects in these diseases. ..
  2. Role of DNA localization in regulating transcription
    JASON BRICKNER; Fiscal Year: 2007
    ..2004). Understanding the role of DMA localization in controlling gene expression may illuminate the cellular and molecular defects in these diseases. ..
  3. Role of DNA localization in regulating transcription
    JASON BRICKNER; Fiscal Year: 2007
    ..We will also define the generality, properties and molecular mechanism of transcriptional memory. Finally, we will test the functional role(s) of gene localization at the nuclear periphery. Project Description Page 6 ..
  4. Role of DNA localization in regulating transcription
    JASON HAYS BRICKNER; Fiscal Year: 2010
    ..2004). Understanding the role of DMA localization in controlling gene expression may illuminate the cellular and molecular defects in these diseases. ..