Markus Bredel

Summary

Affiliation: Northwestern University
Country: USA

Publications

  1. doi request reprint A network model of a cooperative genetic landscape in brain tumors
    Markus Bredel
    Department of Neurological Surgery, Northwestern Brain Tumor Institute and Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3015, USA
    JAMA 302:261-75. 2009
  2. pmc Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults
    Pierre A Robe
    Department of Surgery Neurosurgery, University of Liege, Domaine du Sart Tilman, B35, 4000 Liege, Belgium
    BMC Cancer 9:372. 2009
  3. pmc Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas
    Ajay K Yadav
    Department of Neurological Surgery, Northwestern Brain Tumor Institute, Lurie Center for Cancer Genetics Research, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3015, USA
    JAMA 302:276-89. 2009
  4. pmc Gene-protein correlation in single cells
    Jaclyn J Renfrow
    Northwestern Brain Tumor Institute, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Neuro Oncol 13:880-5. 2011
  5. doi request reprint A phase 2 trial of single-agent bevacizumab given in an every-3-week schedule for patients with recurrent high-grade gliomas
    Jeffrey J Raizer
    Department of Neurology, Northwestern University, Chicago, IL, USA
    Cancer 116:5297-305. 2010

Collaborators

Detail Information

Publications5

  1. doi request reprint A network model of a cooperative genetic landscape in brain tumors
    Markus Bredel
    Department of Neurological Surgery, Northwestern Brain Tumor Institute and Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3015, USA
    JAMA 302:261-75. 2009
    ..A persistent question concerns the biological basis for the coselection of these alterations during gliomagenesis...
  2. pmc Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults
    Pierre A Robe
    Department of Surgery Neurosurgery, University of Liege, Domaine du Sart Tilman, B35, 4000 Liege, Belgium
    BMC Cancer 9:372. 2009
    ..As it presents an excellent safety profile, we initiated a phase 1/2 clinical study of this anti-inflammatory drug for the treatment of recurrent WHO grade 3 and 4 astrocytic gliomas in adults...
  3. pmc Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas
    Ajay K Yadav
    Department of Neurological Surgery, Northwestern Brain Tumor Institute, Lurie Center for Cancer Genetics Research, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3015, USA
    JAMA 302:276-89. 2009
    ..Glioblastomas--uniformly fatal brain tumors--often have both monosomy of chromosome 10 and gains of the epidermal growth factor receptor (EGFR) gene locus on chromosome 7, an association for which the mechanism is poorly understood...
  4. pmc Gene-protein correlation in single cells
    Jaclyn J Renfrow
    Northwestern Brain Tumor Institute, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Neuro Oncol 13:880-5. 2011
    ..We demonstrate that the fluorescent in situ gene protein assay methodology is capable of resolving gene and protein patterns simultaneously on a cell-by-cell basis...
  5. doi request reprint A phase 2 trial of single-agent bevacizumab given in an every-3-week schedule for patients with recurrent high-grade gliomas
    Jeffrey J Raizer
    Department of Neurology, Northwestern University, Chicago, IL, USA
    Cancer 116:5297-305. 2010
    ..The authors evaluated a 3-week schedule of bevacizumab in patients with recurrent high-grade glioma (HGG)...