Research Topics
| C L BennettSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
A comparison of perspectives on prostate cancer: analysis of utility assessments of patients and physiciansC L Bennett
VA Chicago Health Care Systems, Lakeside Division, IL 60611, USA
Eur Urol 32:86-8. 1997..Quality-of-life considerations are important in metastatic prostate cancer. In this study, we interviewed physicians and patients about their assessments and expectations on quality of life as metastatic prostate cancer progresses...- Thrombotic thrombocytopenic purpura associated with clopidogrelC L Bennett
Veterans Affairs Chicago Healthcare System, Department of Medicine, The Robert H Lurie Comprehensive Cancer Center, Northwestern University, IL 60611, USA
N Engl J Med 342:1773-7. 2000..More than 3 million patients have received clopidogrel. We report the clinical and laboratory findings in 11 patients in whom thrombotic thrombocytopenic purpura developed during or soon after treatment with clopidogrel... - Cost analyses of adjunct colony stimulating factors for acute leukemia: can they improve clinical decision makingC L Bennett
Chicago VA Healthcare System Lakeside Division, and Northwestern University, Chicago, IL 60611, USA
Leuk Lymphoma 37:65-70. 2000..In studies of adult and older adult AML patients, both GM-CSF and G-CSF have clinical benefits and can be expected to lead to a decrease in overall costs... - The association between physician reimbursement in the US and use of hematopoietic colony stimulating factors as adjunct therapy for older patients with acute myeloid leukemia: results from the 1997 American Society of Clinical Oncology survey. Health SerC L Bennett
Chicago Veterans Administration Healthsystem, Lakeside Division, USA
Ann Oncol 10:1355-9. 1999..In 1997, the ASCO health services research committee evaluated whether physician reimbursement was a primary determinant in the decision to use G-CSF and GM-CSF in this clinical situation... - Economic analysis of amifostine as adjunctive support for patients with advanced head and neck cancer: preliminary results from a randomized phase II clinical trial from GermanyC L Bennett
Lakeside VA Medical Center, 400 East Ontario Street, Suite 205, Chicago, IL 60611, USA
Cancer Invest 19:107-13. 2001..Additional economic studies alongside randomized phase III trials and from other countries are needed... - Thrombotic thrombocytopenic purpura associated with ticlopidine in the setting of coronary artery stents and stroke preventionC L Bennett
Institute for Health Services Research and Policy Studies, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Ill, USA
Arch Intern Med 159:2524-8. 1999..Recently, Hoffman-LaRoche Pharmaceuticals, following reports of 20 deaths from ticlopidine-associated TTP, updated the information about the hematologic adverse effects of the drug... - The blue cross blue shield assessment technology review: summary of findingsCharles L Bennett
Midwest Center for Health Services and Policy Research, and VA Chicago Healthcare Systems Lakeside Division, The Feinberg School of Medicine, Northwestern University, 400 E Ontario Street, Suite 205 Chicago, IL 60611, USA
Best Pract Res Clin Haematol 18:423-31. 2005..An update of this review, which includes information on quality of life, transfusion requirment, survival and tumor response, for first and second-generation epoetin products is ongoing... - Relation between literacy, race, and stage of presentation among low-income patients with prostate cancerC L Bennett
Chicago Veteran Affairs Administration Healthcare System Lakeside Division, Northwestern University, IL, USA
J Clin Oncol 16:3101-4. 1998..In this study, we evaluated the association of poor literacy skills with higher rates of presentation of advanced stages of prostate cancer among low-income black and white men who received care in equal-access medical systems... 
Cancer insurance policies in Japan and the United StatesC L Bennett
Health Services Research and Development Division, Lakeside Veterans Affairs VA Medical Center, Chicago, IL, USA
West J Med 168:17-22. 1998..Understanding the factors that led to the success of cancer insurance in Japan may assist policymakers in evaluating cancer insurance policies as they become more prevalent in the United States...- Delays in tuberculosis isolation and suspicion among persons hospitalized with HIV-related pneumoniaC L Bennett
The Chicago VA Health Care System Lakeside and Westside Divisions, Loyola University Medical Center, Chicago, IL 60611, USA
Chest 117:110-6. 2000..Despite awareness of HIV-related tuberculosis (TB), nosocomial outbreaks of multidrug-resistant TB among HIV-infected individuals occur... - Spouse ratings of quality of life in patients with metastatic prostate cancer of lower socioeconomic status: an assessment of feasibility, reliability, and validityS J Knight
Veterans Affairs Chicago Health Care System, Lakeside Division, Chicago, Illinois, USA
Urology 57:275-80. 2001..For subjective domains, such as the social domain, direct patient assessments are needed... - Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysisJ Seidenfeld
Blue Cross and Blue Shield Association Technology Evaluation Center, Chicago, Illinois 60601 7680, USA
Ann Intern Med 132:566-77. 2000..To compare luteinizing hormone-releasing hormone (LHRH) agonists with orchiectomy or diethylstilbestrol, and to compare antiandrogens with any of these three alternatives... - Health literacy and shared decision making for prostate cancer patients with low socioeconomic statusS P Kim
Division of Hematology/Oncology, Medical School, Chicago, Illinois, USA
Cancer Invest 19:684-91. 2001..The development of shared decision making tools should include collaborative efforts with the target population to improve the success of shared decision making programs among patients with low health literacy... - Epoetin treatment of anemia associated with cancer therapy: a systematic review and meta-analysis of controlled clinical trialsJ Seidenfeld
Technology Evaluation Center, Blue Cross and Blue Shield Association, Chicago, IL 60601 7680, USA
J Natl Cancer Inst 93:1204-14. 2001..Evidence is insufficient to determine whether initiating epoetin earlier spares more patients from transfusion or results in better quality of life than waiting until hemoglobin concentrations decline to nearly 10 g/dL... - The role of inadequate health literacy skills in colorectal cancer screeningT C Davis
Department of Medicine, Louisiana State University Medical Center, Shreveport, Louisiana, USA
Cancer Invest 19:193-200. 2001..The theoretical model also provides insights into strategies for improving knowledge, attitudes, and beliefs and screening rates for this challenging patient population... - Economic analysis of granulocyte colony stimulating factor as adjunct therapy for older patients with acute myelogenous leukemia (AML): estimates from a Southwest Oncology Group clinical trialC L Bennett
VA Chicago Health Care System-Lakeside, Chicago, Illinois 60611, USA
Cancer Invest 19:603-10. 2001..Whether the benefits of G-CSF therapy justify its use in individual patients with acute leukemia for the present remains a matter of clinical judgment... - The relation between physician experience and patterns of care for patients with AIDS-related Pneumocystis carinii pneumonia: results from a survey of 1,500 physicians in the United StatesP B Bach
Robert Wood Johnson Clinical Scholars Program, The University of Chicago, IL, USA
Chest 115:1563-9. 1999..To determine whether physician experience and specialty influence the approach to care of AIDS patients with pneumonia, we surveyed physicians about their management of possible Pneumocystis carinii pneumonia (PCP) infection... - Combined androgen blockade with nonsteroidal antiandrogens for advanced prostate cancer: a systematic reviewB Schmitt
Veterans Administration Chicago Healthcare System/Lakeside Division, Chicago, Illinois, USA
Urology 57:727-32. 2001..Appropriate patients with metastatic prostate cancer should be informed of the potential benefits, toxicities, and out-of-pocket expenditures... - Relation between literacy and HIV treatment knowledge among patients on HAART regimensM S Wolf
Center for Healthcare Studies, Feinberg School of Medicine at Northwestern University, Chicago, IL 60611, USA
AIDS Care 17:863-73. 2005..Patients with limited literacy skills may lack essential knowledge related to their HIV treatment. Clinicians may require additional training for improving communication with these patients... - Identifying providers of care to individuals with human immunodeficiency virus for a mail survey using a prescription tracking databaseP B Bach
Department of Medicine, The Harris School of Public Policy, The University of Chicago, Illinois, USA
J Clin Epidemiol 52:147-50. 1999..This study suggests that prescription tracking databases can be used to identify the breadth of physician/subjects who provide care for patients with HIV infection... - Improving rates of cervical cancer screening and Pap smear follow-up for low-income women with limited health literacyS T Lindau
University of Chicago, Robert Wood Johnson Clinical Scholars Program, Chicago, Illinois, USA
Cancer Invest 19:316-23. 2001..Our goal is to improve our understanding of the health impact of low literacy among urban women and to inspire interventions that will promote disease prevention behaviors in this population, particularly with regard to cervical cancer... - Granulocyte-colony stimulating factor administration to healthy individuals and persons with chronic neutropenia or cancer: an overview of safety considerations from the Research on Adverse Drug Events and Reports projectC C Tigue
Division of Hematology Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Bone Marrow Transplant 40:185-92. 2007..There are questions about a causal relationship between G-CSF administration and acute leukemia, but more long-term safety data from database registries are needed to adequately evaluate such a relationship... - Evaluating the total costs of chemotherapy-induced toxicity: results from a pilot study with ovarian cancer patientsE A Calhoun
The Institute for Health Services Research and Policy Studies, Department of Obstetrics and Gynecology, The Robert H Lurie Comprehensive Cancer Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
Oncologist 6:441-5. 2001..The objective of this study was to evaluate the feasibility of obtaining detailed and comprehensive cost information from patients who experienced neutropenia, thrombocytopenia, or neurotoxicity during treatment... - Clinical trials: are they a good buy?C L Bennett
Chicago Veterans Affairs Healthcare System Lakeside Division, IL 60611, USA
J Clin Oncol 19:4330-9. 2001..In this study, we reviewed the empirical data on costs of clinical trials versus standard care and summarized the current status of policy initiatives related to clinical trial insurance reimbursement... - Legal, financial, and public health consequences of transfusion-transmitted hepatitis C virus in persons with haemophiliaC Angelotta
Division of Hematology Oncology, Department of Medicine, Northwestern University, Chicago, IL 60611, USA
Vox Sang 93:159-65. 2007..Relatively little attention has been paid to similar hepatitis C virus (HCV) concerns since the first cases of HCV-infected persons with haemophilia were identified in 1989... - Growth of oncology physician practice management companiesK Mighion
Robert H Lurie Cancer Center, Institute for Health Services and Policy Research, Northwestern University, Chicago, Illinois, USA
Cancer Invest 17:362-70. 1999..This review article is of broad interest to oncologists practicing in the United States and is meant to provide a useful reference for considering a physician practice management company as a business partner... - Quality improvement efforts in oncology: are we ready to begin?C L Bennett
Chicago VA Healthcare System Lakeside Division, Robert H Lurie Comprehensive Cancer Center, Division of Hematology Oncology of Northwestern University, Chicago, Illinois, USA
Cancer Invest 19:86-95. 2001..In this article, we describe the potential benefits and drawbacks of CQI efforts in oncology, review experiences with four different CQI cancer programs, and make recommendations about future CQI efforts... - HIV-related Pneumocystis carinii pneumonia in older patients hospitalized in the early HAART eraB Kim
Department of Medicine, Northwestern University Medical School, Chicago, Ill, USA
J Gen Intern Med 16:583-9. 2001..Continued vigilance for the possibility of HIV and HIV-related PCP among persons > or =50 years of age who present with new pulmonary symptoms should be encouraged... - Health literacy and patient knowledge in a Southern US HIV clinicM S Wolf
Center for Healthcare Studies, Department of General Internal Medicine, Feinberg School of Medicine, Northwestern University, 676 N St Clair Street, Suite 200, Chicago, IL 60611, USA
Int J STD AIDS 15:747-52. 2004..005). Physicians may require training to appropriately convey health information to patients of low literacy... - Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of HematologyJ Douglas Rizzo
Medical College of Wisconsin, Milwaukee, WI, USA
J Clin Oncol 20:4083-107. 2002..Therefore, for anemic patients with hematologic malignancies, it is recommended that physicians initiate conventional therapy and observe hematologic response before considering use of epoetin... - Cancer- and chemotherapy-induced anemiaGeorge M Rodgers
Huntsman Cancer Institute, University of Utah, Utah, USA
J Natl Compr Canc Netw 6:536-64. 2008 - Erythropoietin, uncertainty principle and cancer related anaemiaOtavio Clark
Interdisciplinary Oncology Program H, Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, FL, USA
BMC Cancer 2:23. 2002..We also wanted to demonstrate that cumulative meta-analysis (CMA) can be used to resolve uncertainty regarding clinical questions... - Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Hematology/American Society of Clinical Oncology clinical practice guideline updateJ Douglas Rizzo
Medical College of Wisconsin, Milwaukee, WI, USA
Blood 111:25-41. 2008..The guideline was expanded to address use of darbepoetin and thromboembolic risk associated with these agents... - Effectiveness of erythropoietin in the treatment of patients with malignancies: methods and preliminary results of a Cochrane reviewJulia F Bohlius
Cochrane Hematological Malignancies Group, Department I of Internal Medicine, University of Cologne, Kerpener Street 9, 50924 Cologne, Germany
Best Pract Res Clin Haematol 18:449-54. 2005..Data extraction and quality assessment were done in duplicate. All authors were contacted to obtain missing data. Out of 33 eligible studies, 27 trials with 3,287 randomized patients were included... - Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Clinical Oncology/American Society of Hematology clinical practice guideline updateJ Douglas Rizzo
Medical College of Wisconsin, Milwaukee, WI, USA
J Clin Oncol 26:132-49. 2008..The guideline was expanded to address use of darbepoetin and thromboembolic risk associated with these agents... - Use of erythropoietin in cancer patients: assessment of oncologists' practice patterns in the United States and other countriesJared R Adams
Department of Veterans Affairs, the MidWest Center for Health Services and Policy Research and the Veterans Affairs Chicago Healthcare System/Lakeside Division, Chicago, Illinois, USA
Am J Med 116:28-34. 2004..01). CONCLUSION: Financial considerations and a hemoglobin level <10 g/dL appear to influence erythropoietin use in the United States, whereas financial considerations alone determine erythropoietin use abroad... 
Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemiaCharles L Bennett
VA Chicago Healthcare System, Department of Medicine, Northwestern University Feinberg School of Medicine, and Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois 60611, USA
JAMA 299:914-24. 2008..Although systematic overviews of trials have identified venous thromboembolism (VTE) risks, none have identified mortality risks with ESAs...- Epoetin-associated pure red cell aplasia: past, present, and future considerationsJune M McKoy
Division of Hematology Oncology and Geriatric Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Transfusion 48:1754-62. 2008..In 1998, epoetin-associated pure red cell aplasia (PRCA) was first reported and causation was attributed to formulations without human serum albumin (HSA), subcutaneous administration, and uncoated rubber stoppers... - Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinomaDavid J Samson
Technology Evaluation Center, Blue Cross and Blue Shield Association, Washington, DC 20005, USA
Cancer 95:361-76. 2002..Outcomes of interest included overall, cancer specific, and progression-free survival; time to treatment failure; adverse events; and quality of life... - Cost considerations in the management of cancer in the older patientJune M McKoy
Division of Geriatrics, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Feinberg School of Medicine, Division of Hematology Oncology, Chicago, Illinois 60611, USA
Oncology (Williston Park) 21:851-7; discussion 858, 860, 862 passim. 2007..Additional research about cancer costs may also lead to reforms in cancer care reimbursement, and therefore provide access to affordable health care for older patients... - Dermatologic challenges in cancer patients and survivorsRania Agha
Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Oncology (Williston Park) 21:1462-72; discussion 1473, 1476, 1481 passim. 2007..This review provides a basis for the understanding of dermatologic events in the oncology setting, in order to promote attentive care to cutaneous health in cancer patients and survivors... - Cancer-associated neutropenic fever: clinical outcome and economic costs of emergency department careD Mark Courtney
VA Lakeside Medical Center, Division of General Internal Medicine, Department of Medicine, 400 E Ontario Street, Suite 205, Chicago, Illinois 60611, USA
Oncologist 12:1019-26. 2007..Costs of ED care were similar to the cost of a single day of inpatient care. Disclosure of potential conflicts of interest is found at the end of this article... - Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the National Cancer Institute-sponsored cooperative oncology groups, 1955 to 2006Benjamin Djulbegovic
H Lee Moffitt Cancer Center, 12902 Magnolia Dr, MRC, Room 2067H, Tampa, FL 33612, USA
Arch Intern Med 168:632-42. 2008..We assessed how often experimental cancer treatments that undergo testing in randomized clinical trials (RCTs) result in discovery of successful new interventions... - Does reimbursement affect physicians' decision making? Examples from the use of recombinant erythropoietinJune M McKoy
Division of Geriatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Cancer Treat Res 140:235-51. 2008 - Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of HematologyJ Douglas Rizzo
Medical College of Wisconsin, Milwaukee, WI 53226, USA
Blood 100:2303-20. 2002..Therefore, for anemic patients with hematologic malignancies it is recommended that physicians initiate conventional therapy and observe hematologic response before considering use of epoetin... - Evaluating the total costs of chemotherapy-induced febrile neutropenia: results from a pilot study with community oncology cancer patientsCharles L Bennett
The Robert H Lurie Comprehensive Cancer Center, Divison of Hematology Oncology, Northwestern University, Chicago, Illinois, USA
Oncologist 12:478-83. 2007..Here, we evaluate the feasibility of obtaining detailed and comprehensive cost information on patients who experience febrile neutropenia during cancer chemotherapy treatment... - Thalidomide- and lenalidomide-associated thromboembolism among patients with cancerCharles L Bennett
JAMA 296:2558-60. 2006 - Quality of life after a diagnosis of prostate cancer among men of lower socioeconomic status: results from the Veterans Affairs Cancer of the Prostate Outcomes StudyAmy K Siston
Department of Psychiatry and Behavioral Sciences, Northwestern University Medical School, Chicago, Illinois 60611, USA
Urology 61:172-8. 2003..Our study, among the first to assess the QOL at baseline before treatment, provides meaningful information on general treatment effects, which are directly relevant to clinicians when discussing treatment options with patients... - A comparison of ovarian cancer treatments: analysis of utility assessments of ovarian cancer patients, at-risk population, general population, and physiciansElizabeth A Calhoun
Obstetrics and Gynecology Gynecologic Oncology, Northwestern University Medical School, Chicago, IL 60611, USA
Gynecol Oncol 93:164-9. 2004..In this study, we elicited assessments of toxicity from women with ovarian cancer, women at increased risk of developing ovarian cancer, women in the general population, and gynecologic oncologists... - Ethnic variation in localized prostate cancer: a pilot study of preferences, optimism, and quality of life among black and white veteransSara J Knight
Mental Health Service, Research and Development, Department of Veterans Affairs Medical Center, San Francisco 94121, USA
Clin Prostate Cancer 3:31-7. 2004..Quality-of-life declines were common to both groups during the first year after diagnosis, but ethnic variation occurred with respect to nausea and vomiting, sexual interest, and weight gain... - Estimating the cost of cancer: results on the basis of claims data analyses for cancer patients diagnosed with seven types of cancer during 1999 to 2000Stella Chang
Medstat Inc, Washington, DC 20008, USA
J Clin Oncol 22:3524-30. 2004..We derive estimates of the costs of cancer using administrative databases, which include claims and employment-related information on individuals insured by private or Medicare supplemental health plans... - Pure red-cell aplasia and epoetin therapyCharles L Bennett
MidWest Center for Health Services Research and Policy Studies, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60611, USA
N Engl J Med 351:1403-8. 2004.... - Evaluating the total costs of cancer. The Northwestern University Costs of Cancer ProgramElizabeth A Calhoun
Robert H Lurie Comprehensive, Cancer Center, Institute of Health Services, Health Policy Research, Northwestern University, Medical School, USA
Oncology (Williston Park) 17:109-14; discussion 119-21. 2003..In this article, we outline the theoretical framework associated with a study of cancer costs and summarize findings from our ongoing pilot studies in this area... - Clinical characteristics of erythropoietin-associated pure red cell aplasiaKenneth R Carson
Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine and the Robert H Lurie Comprehensive Cancer Center, Chicago, IL, USA
Best Pract Res Clin Haematol 18:467-72. 2005..Timely identification and treatment of this rare syndrome can prevent the development of severe red blood cell transfusion requirements and the potential complications of iron overload, which results from these transfusions... - Granulocyte colony--stimulating factor for chemotherapy-induced neutropenia in patients with small cell lung cancer : the 40% rule revisitedElizabeth A Calhoun
Department of Health Policy and Administration, University of Illinois at Chicago, Chicago, IL 60612, USA
Pharmacoeconomics 23:767-75. 2005..Future cost-effectiveness studies of medications such as pegfilgrastim should attempt to capture the societal perspective by incorporating productivity-related costs and using base-case rates of FN reported in the literature... - Reducing adverse drug events in the outpatient chemotherapy setting: attention must be paidJonathan R Nebeker
Cancer 104:2289-91. 2005 - 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guidelineThomas J Smith
American Society of Clinical Oncology, Cancer Policy and Clinical Affairs, Alexandria, VA 22314, USA
J Clin Oncol 24:3187-205. 2006.... - Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patientsJulia Bohlius
Department of Internal Medicine I, University of Cologne, Germany
J Natl Cancer Inst 98:708-14. 2006..08, 95% CI = 0.99 to 1.18; 42 trials and 8167 patients). Caution is advised when using epoetin or darbepoetin in combination with thrombogenic chemotherapeutic agents or for cancer patients who are at high risk for thrombo-embolic events...