Research Topics
Genomes and GenesSpecies | C L BennettSummaryAffiliation: Northwestern University Country: USA Publications
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Publications
Erythropoietin, uncertainty principle and cancer related anaemiaOtavio Clark
Interdisciplinary Oncology Program H, Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, FL, USA
BMC Cancer 2:23. 2002..We also wanted to demonstrate that cumulative meta-analysis (CMA) can be used to resolve uncertainty regarding clinical questions...
Clinical trials: are they a good buy?C L Bennett
Chicago Veterans Affairs Healthcare System Lakeside Division, IL 60611, USA
J Clin Oncol 19:4330-9. 2001..In this study, we reviewed the empirical data on costs of clinical trials versus standard care and summarized the current status of policy initiatives related to clinical trial insurance reimbursement...
Adverse effects of drugs used to treat hematologic malignancies: surveillance efforts from the research on adverse drug events and reports projectCharles L Bennett
Veterans Affairs Center of Complex Chronic Care, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA
Semin Thromb Hemost 33:365-72. 2007..This article reviews the features of the safety program maintained by the U.S. Food and Drug Administration and the RADAR program...
Cost analyses of adjunct colony stimulating factors for older patients with acute myeloid leukaemia : can they improve clinical decision making?Charles L Bennett
Chicago VA Healthcare System Lakeside Division, Midwest Center for Health Services and Policy Research, Illinois 60611, USA
Drugs Aging 20:479-83. 2003..These data may be useful to physicians faced with concerns over clinical and economic factors associated with CSF use as adjunct therapy for older persons with AML...
Evaluation of serious adverse drug reactions: a proactive pharmacovigilance program (RADAR) vs safety activities conducted by the Food and Drug Administration and pharmaceutical manufacturersCharles L Bennett
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Arch Intern Med 167:1041-9. 2007..We compare safety efforts for evaluating serious ADRs conducted by the FDA and pharmaceutical manufacturers vs the RADAR project...
Perspectives on the value of American Society of Clinical Oncology clinical guidelines as reported by oncologists and health maintenance organizationsCharles L Bennett
VA Midwest Center for Health Services and Policy Research, Department of Veterans Affairs, Chicago Healthcare System Lakeside Division, Chicago, USA
J Clin Oncol 21:937-41. 2003..ASCO members and Health Maintenance Organizations (HMOs) were surveyed on the value and implementation of ASCO guidelines. In this article, we summarize our findings...
Thalidomide-associated deep vein thrombosis and pulmonary embolismCharles L Bennett
Midwest Center for Health Services and Policy Research, Chicago VA Healthcare System/Lakeside Division, 400 East Ontario, Room 205, Chicago, IL 60611, USA
Am J Med 113:603-6. 2002
Costs and cost-effectiveness of a low-intensity patient-directed intervention to promote colorectal cancer screeningVeena Shankaran
MPP, Division of Hematology Oncology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Olson Pavilion Suite 8250, Chicago, IL 60611, USA
J Clin Oncol 25:5248-53. 2007..The objective of this secondary analysis is to assess the cost-effectiveness of this intervention...
Racial variation in CAG repeat lengths within the androgen receptor gene among prostate cancer patients of lower socioeconomic statusCharles L Bennett
Mid West Center for Health Services Research and Development, Department of Veterans Affairs Medical Center, Chicago, IL 60611, USA
J Clin Oncol 20:3599-604. 2002..To our knowledge, our study is the first to report on CAG repeat lengths in a cohort of prostate cancer patients, which includes large numbers of African-American men...
Cost analyses of granulocyte colony stimulating factor: a focus on older patients with cancerCharles L Bennett
The Chicago VA Healthcare System Lakeside Division, The Midwest Center for Health Services and Policy Research, Robert H Lurie Comprehensive Cancer Center, Chicago, IL 60611, USA
Crit Rev Oncol Hematol 48:S71-4. 2003..These data may be useful to physicians faced with concerns over clinical and economic factors associated with G-CSF use as adjunct therapy for SCLC...
Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemiaCharles L Bennett
VA Chicago Healthcare System, Department of Medicine, Northwestern University Feinberg School of Medicine, and Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois 60611, USA
JAMA 299:914-24. 2008..Although systematic overviews of trials have identified venous thromboembolism (VTE) risks, none have identified mortality risks with ESAs...
The Research on Adverse Drug Events and Reports (RADAR) projectCharles L Bennett
Jesse Brown VA Medical Center Mid West Center for Health Services and Policy Research, Chicago, Ill 60611, USA
JAMA 293:2131-40. 2005....
Long-term outcome of individuals with pure red cell aplasia and antierythropoietin antibodies in patients treated with recombinant epoetin: a follow-up report from the Research on Adverse Drug Events and Reports (RADAR) ProjectCharles L Bennett
MidWest Center for Health Services Research and Policy Studies, VA Chicago Healthcare System, Chicago, IL, USA
Blood 106:3343-7. 2005..Reinitiation of epoetin therapy among individuals could be considered if antierythropoietin antibodies are undetectable...
Pharmacoeconomics of liposomal anthracycline therapyCharles L Bennett
Veterans Affairs Chicago Healthcare System Lakeside, Institute of Health Services and Policy Studies, Northwestern University, Chicago, IL, USA
Semin Oncol 31:191-5. 2004..The decision to allocate health care resources to liposomal anthracycline treatment must therefore include consideration of cost-effectiveness and potential cost savings owing to improved tolerability...
Pure red-cell aplasia and epoetin therapyCharles L Bennett
MidWest Center for Health Services Research and Policy Studies, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60611, USA
N Engl J Med 351:1403-8. 2004....
Haematological malignancies developing in previously healthy individuals who received haematopoietic growth factors: report from the Research on Adverse Drug Events and Reports (RADAR) projectCharles L Bennett
VA Midwest Center for Health Services and Policy Research, the Jesse Brown VA Medical Center, Chicago, IL, USA
Br J Haematol 135:642-50. 2006..While a causal relationship with haematological malignancies cannot be demonstrated, long-term follow-up among healthy individuals who receive haematopoietic growth factors is needed...
Two mechanistic pathways for thienopyridine-associated thrombotic thrombocytopenic purpura: a report from the SERF-TTP Research Group and the RADAR ProjectCharles L Bennett
VA Center for Management of Complex Chronic Care at Jesse Brown VA Medical Center, Division of Hematology Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
J Am Coll Cardiol 50:1138-43. 2007..We sought to describe clinical and laboratory findings for a large cohort of patients with thienopyridine-associated thrombotic thrombocytopenic purpura (TTP)...
Evaluating the total costs of chemotherapy-induced febrile neutropenia: results from a pilot study with community oncology cancer patientsCharles L Bennett
The Robert H Lurie Comprehensive Cancer Center, Divison of Hematology Oncology, Northwestern University, Chicago, Illinois, USA
Oncologist 12:478-83. 2007..Here, we evaluate the feasibility of obtaining detailed and comprehensive cost information on patients who experience febrile neutropenia during cancer chemotherapy treatment...
Relation between literacy, race, and stage of presentation among low-income patients with prostate cancerC L Bennett
Chicago Veteran Affairs Administration Healthcare System Lakeside Division, Northwestern University, IL, USA
J Clin Oncol 16:3101-4. 1998..In this study, we evaluated the association of poor literacy skills with higher rates of presentation of advanced stages of prostate cancer among low-income black and white men who received care in equal-access medical systems...
Delays in tuberculosis isolation and suspicion among persons hospitalized with HIV-related pneumoniaC L Bennett
The Chicago VA Health Care System Lakeside and Westside Divisions, Loyola University Medical Center, Chicago, IL 60611, USA
Chest 117:110-6. 2000..Despite awareness of HIV-related tuberculosis (TB), nosocomial outbreaks of multidrug-resistant TB among HIV-infected individuals occur...
A comparison of perspectives on prostate cancer: analysis of utility assessments of patients and physiciansC L Bennett
VA Chicago Health Care Systems, Lakeside Division, IL 60611, USA
Eur Urol 32:86-8. 1997..Quality-of-life considerations are important in metastatic prostate cancer. In this study, we interviewed physicians and patients about their assessments and expectations on quality of life as metastatic prostate cancer progresses...
Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysisJ Seidenfeld
Blue Cross and Blue Shield Association Technology Evaluation Center, Chicago, Illinois 60601 7680, USA
Ann Intern Med 132:566-77. 2000..To compare luteinizing hormone-releasing hormone (LHRH) agonists with orchiectomy or diethylstilbestrol, and to compare antiandrogens with any of these three alternatives...
Use of erythropoietin in cancer patients: assessment of oncologists' practice patterns in the United States and other countriesJared R Adams
Department of Veterans Affairs, the MidWest Center for Health Services and Policy Research and the Veterans Affairs Chicago Healthcare System/Lakeside Division, Chicago, Illinois, USA
Am J Med 116:28-34. 2004..01). CONCLUSION: Financial considerations and a hemoglobin level <10 g/dL appear to influence erythropoietin use in the United States, whereas financial considerations alone determine erythropoietin use abroad...
Process evaluation in an intervention designed to improve rates of colorectal cancer screening in a VA medical centerMarian L Fitzgibbon
University of Illinois at Chicago, Section of Health Promotion Research, Department of Medicine, IL 60608, USA
Health Promot Pract 8:273-81. 2007..05). The patient intervention did not have the desired impact. The subgroup of patients in the patient intervention was not more likely to complete CRC screening...
Epoetin treatment of anemia associated with cancer therapy: a systematic review and meta-analysis of controlled clinical trialsJ Seidenfeld
Technology Evaluation Center, Blue Cross and Blue Shield Association, Chicago, IL 60601 7680, USA
J Natl Cancer Inst 93:1204-14. 2001..Evidence is insufficient to determine whether initiating epoetin earlier spares more patients from transfusion or results in better quality of life than waiting until hemoglobin concentrations decline to nearly 10 g/dL...
HIV-related pneumonia care in older patients hospitalized in the early HAART eraAshish Sureka
Buehler Center on Aging, Northwestern University Medical School, Chicago, Illinois, USA
AIDS Patient Care STDS 18:99-107. 2004..Physicians should develop strategies that increase awareness of the possibility of HIV infection in older individuals...
Clopidogrel-associated TTP: an update of pharmacovigilance efforts conducted by independent researchers, pharmaceutical suppliers, and the Food and Drug AdministrationAnaadriana Zakarija
VA Chicago Healthcare System, VA Midwest Center for Health Services and Policy Research, Division of Hematology/Oncology, Department of Medicine, Northwestern University Medical Center, Chicago, Ill, USA
Stroke 35:533-7. 2004..Clopidogrel-associated TTP often occurs within 2 weeks of drug initiation, occasionally relapses, and has a high mortality if not treated promptly...
Evaluating the total costs of chemotherapy-induced toxicity: results from a pilot study with ovarian cancer patientsE A Calhoun
The Institute for Health Services Research and Policy Studies, Department of Obstetrics and Gynecology, The Robert H Lurie Comprehensive Cancer Center, Northwestern University Medical School, Chicago, Illinois 60611, USA
Oncologist 6:441-5. 2001..The objective of this study was to evaluate the feasibility of obtaining detailed and comprehensive cost information from patients who experienced neutropenia, thrombocytopenia, or neurotoxicity during treatment...
Spouse ratings of quality of life in patients with metastatic prostate cancer of lower socioeconomic status: an assessment of feasibility, reliability, and validityS J Knight
Veterans Affairs Chicago Health Care System, Lakeside Division, Chicago, Illinois, USA
Urology 57:275-80. 2001..For subjective domains, such as the social domain, direct patient assessments are needed...
Granulocyte colony--stimulating factor for chemotherapy-induced neutropenia in patients with small cell lung cancer : the 40% rule revisitedElizabeth A Calhoun
Department of Health Policy and Administration, University of Illinois at Chicago, Chicago, IL 60612, USA
Pharmacoeconomics 23:767-75. 2005..Future cost-effectiveness studies of medications such as pegfilgrastim should attempt to capture the societal perspective by incorporating productivity-related costs and using base-case rates of FN reported in the literature...
Ethnic variation in localized prostate cancer: a pilot study of preferences, optimism, and quality of life among black and white veteransSara J Knight
Mental Health Service, Research and Development, Department of Veterans Affairs Medical Center, San Francisco 94121, USA
Clin Prostate Cancer 3:31-7. 2004..Quality-of-life declines were common to both groups during the first year after diagnosis, but ethnic variation occurred with respect to nausea and vomiting, sexual interest, and weight gain...
Social stigma concerns and HIV medication adherenceLance S Rintamaki
Midwest Center for Health Services and Policy Research, Veteran Affairs Chicago Healthcare System, Chicago, Illinois, USA
AIDS Patient Care STDS 20:359-68. 2006....
Proxy assessment of health-related quality of life in african american and white respondents with prostate cancer: perspective mattersA Simon Pickard
Department of Pharmacy Practice and Pharmacy Administration, Center for Pharmacoeconomic Research, College of Pharmacy, University of Illinois at Chicago, Chicago, USA
Med Care 47:176-83. 2009....
The relation between physician experience and patterns of care for patients with AIDS-related Pneumocystis carinii pneumonia: results from a survey of 1,500 physicians in the United StatesP B Bach
Robert Wood Johnson Clinical Scholars Program, The University of Chicago, IL, USA
Chest 115:1563-9. 1999..To determine whether physician experience and specialty influence the approach to care of AIDS patients with pneumonia, we surveyed physicians about their management of possible Pneumocystis carinii pneumonia (PCP) infection...
Economic analysis of granulocyte colony stimulating factor as adjunct therapy for older patients with acute myelogenous leukemia (AML): estimates from a Southwest Oncology Group clinical trialC L Bennett
VA Chicago Health Care System-Lakeside, Chicago, Illinois 60611, USA
Cancer Invest 19:603-10. 2001..Whether the benefits of G-CSF therapy justify its use in individual patients with acute leukemia for the present remains a matter of clinical judgment...
The role of inadequate health literacy skills in colorectal cancer screeningT C Davis
Department of Medicine, Louisiana State University Medical Center, Shreveport, Louisiana, USA
Cancer Invest 19:193-200. 2001..The theoretical model also provides insights into strategies for improving knowledge, attitudes, and beliefs and screening rates for this challenging patient population...
Granulocyte-colony stimulating factor administration to healthy individuals and persons with chronic neutropenia or cancer: an overview of safety considerations from the Research on Adverse Drug Events and Reports projectC C Tigue
Division of Hematology Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Bone Marrow Transplant 40:185-92. 2007..There are questions about a causal relationship between G-CSF administration and acute leukemia, but more long-term safety data from database registries are needed to adequately evaluate such a relationship...
Does reimbursement affect physicians' decision making? Examples from the use of recombinant erythropoietinJune M McKoy
Division of Geriatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Cancer Treat Res 140:235-51. 2008
Identifying providers of care to individuals with human immunodeficiency virus for a mail survey using a prescription tracking databaseP B Bach
Department of Medicine, The Harris School of Public Policy, The University of Chicago, Illinois, USA
J Clin Epidemiol 52:147-50. 1999..This study suggests that prescription tracking databases can be used to identify the breadth of physician/subjects who provide care for patients with HIV infection...
Cancer insurance policies in Japan and the United StatesC L Bennett
Health Services Research and Development Division, Lakeside Veterans Affairs VA Medical Center, Chicago, IL, USA
West J Med 168:17-22. 1998..Understanding the factors that led to the success of cancer insurance in Japan may assist policymakers in evaluating cancer insurance policies as they become more prevalent in the United States...
Thrombotic thrombocytopenic purpura associated with ticlopidine in the setting of coronary artery stents and stroke preventionC L Bennett
Institute for Health Services Research and Policy Studies, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Ill, USA
Arch Intern Med 159:2524-8. 1999..Recently, Hoffman-LaRoche Pharmaceuticals, following reports of 20 deaths from ticlopidine-associated TTP, updated the information about the hematologic adverse effects of the drug...
Improving rates of cervical cancer screening and Pap smear follow-up for low-income women with limited health literacyS T Lindau
University of Chicago, Robert Wood Johnson Clinical Scholars Program, Chicago, Illinois, USA
Cancer Invest 19:316-23. 2001..Our goal is to improve our understanding of the health impact of low literacy among urban women and to inspire interventions that will promote disease prevention behaviors in this population, particularly with regard to cervical cancer...
Cost analyses of adjunct colony stimulating factors for acute leukemia: can they improve clinical decision makingC L Bennett
Chicago VA Healthcare System Lakeside Division, and Northwestern University, Chicago, IL 60611, USA
Leuk Lymphoma 37:65-70. 2000..In studies of adult and older adult AML patients, both GM-CSF and G-CSF have clinical benefits and can be expected to lead to a decrease in overall costs...
Combined androgen blockade with nonsteroidal antiandrogens for advanced prostate cancer: a systematic reviewB Schmitt
Veterans Administration Chicago Healthcare System/Lakeside Division, Chicago, Illinois, USA
Urology 57:727-32. 2001..Appropriate patients with metastatic prostate cancer should be informed of the potential benefits, toxicities, and out-of-pocket expenditures...
Economic analysis of amifostine as adjunctive support for patients with advanced head and neck cancer: preliminary results from a randomized phase II clinical trial from GermanyC L Bennett
Lakeside VA Medical Center, 400 East Ontario Street, Suite 205, Chicago, IL 60611, USA
Cancer Invest 19:107-13. 2001..Additional economic studies alongside randomized phase III trials and from other countries are needed...
Thrombotic thrombocytopenic purpura associated with clopidogrelC L Bennett
Veterans Affairs Chicago Healthcare System, Department of Medicine, The Robert H Lurie Comprehensive Cancer Center, Northwestern University, IL 60611, USA
N Engl J Med 342:1773-7. 2000..More than 3 million patients have received clopidogrel. We report the clinical and laboratory findings in 11 patients in whom thrombotic thrombocytopenic purpura developed during or soon after treatment with clopidogrel...
Relation between literacy and HIV treatment knowledge among patients on HAART regimensM S Wolf
Center for Healthcare Studies, Feinberg School of Medicine at Northwestern University, Chicago, IL 60611, USA
AIDS Care 17:863-73. 2005..Patients with limited literacy skills may lack essential knowledge related to their HIV treatment. Clinicians may require additional training for improving communication with these patients...
Health literacy and patient knowledge in a Southern US HIV clinicM S Wolf
Center for Healthcare Studies, Department of General Internal Medicine, Feinberg School of Medicine, Northwestern University, 676 N St Clair Street, Suite 200, Chicago, IL 60611, USA
Int J STD AIDS 15:747-52. 2004..005). Physicians may require training to appropriately convey health information to patients of low literacy...
G-CSF is not necessary to maintain over 99% dose-intensity with ABVD in the treatment of Hodgkin lymphoma: low toxicity and excellent outcomes in a 10-year analysisAndrew M Evens
Division of Hematology Oncology, Lymphoma Program, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Br J Haematol 137:545-52. 2007..0% and OS 91.3% (P = 0.46 and 0.67 respectively). Our experience suggests that ABVD may be safely and effectively administered at >99% dose-intensity without G-CSF support, regardless of the ANC...
A qualitative study of literacy and patient response to HIV medication adherence questionnairesMichael S Wolf
Institute for Healthcare Studies, Dept of General Internal Medicine, Northwestern University, 676 N St Clair Street, Chicago, IL 60611, USA
J Health Commun 10:509-17. 2005..Patients receiving treatment for HIV infection, especially those with limited literacy skills, may find it difficult to respond to existing HIV medication adherence questionnaires...
Costs and cost effectiveness of a health care provider-directed intervention to promote colorectal cancer screening among VeteransMichael S Wolf
Institute for Healthcare Studies, Department of Medicine, Northwestern University, Illinois, USA
J Clin Oncol 23:8877-83. 2005..Our findings may have broad applicability because a 2005 Medicare initiative will provide the VA electronic medical record system as a free benefit to all US physicians...
Local perspective of the impact of the HIPAA privacy rule on researchMichael S Wolf
Institute for Health Services Research and Policy Studies, Feinberg School of Medicine, and Robert H Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois 60611, USA
Cancer 106:474-9. 2006..The setting was a natural experiment which involved a single-site, clinical research study that was initiated before the enactment of HIPAA and subsequently modified to be compliant with the new policy...
Feasibility and effectiveness of the NEST13+ as a screening tool for advanced illness care needsKaren G Scandrett
Buehler Center on Aging, Health and Society, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Palliat Med 13:161-9. 2010..A comprehensive whole-person approach might improve processes and outcomes of care for patients with cancer...
Cancer therapy associated bone loss: implications for hip fractures in mid-life women with breast cancerBeatrice J Edwards
Bone Health and Osteoporosis Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Clin Cancer Res 17:560-8. 2011..Aromatase inhibitors (AIs) have been recently associated with hip fractures. We present a case series of breast cancer survivors and a systematic review of bone health care in breast cancer...
Literacy, race, and PSA level among low-income men newly diagnosed with prostate cancerMichael S Wolf
Robert H Lurie Comprehensive Cancer Center, Institute for Healthcare Studies and Division of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Urology 68:89-93. 2006..We investigated whether, after adjusting for literacy, race was a significant independent predictor of greater PSA levels among men with newly diagnosed prostate cancer...
Hepatotoxicity associated with long- versus short-course HIV-prophylactic nevirapine use: a systematic review and meta-analysis from the Research on Adverse Drug events And Reports (RADAR) projectJune M McKoy
Department of Medicine, Northwestern University Feinberg School of Medicine, and Department of Pharmacy, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
Drug Saf 32:147-58. 2009..We describe the incidence of hepatotoxicity with short- versus long-course nevirapine-containing regimens in these groups...
Epoetin-associated pure red cell aplasia: past, present, and future considerationsJune M McKoy
Division of Hematology Oncology and Geriatric Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Transfusion 48:1754-62. 2008..In 1998, epoetin-associated pure red cell aplasia (PRCA) was first reported and causation was attributed to formulations without human serum albumin (HSA), subcutaneous administration, and uncoated rubber stoppers...
Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 yearsKarl Y Bilimoria
Cancer Programs, American College Surgeons, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Ann Surg 249:63-71. 2009..Previous studies have shown an increasing incidence of small bowel tumors in the United States. Our objective was to assess this increase by examining changes in histology-specific incidence, treatment, and survival...
Literacy, self-efficacy, and HIV medication adherenceMichael S Wolf
Health Literacy and Learning Program HeLP, Institute for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Patient Educ Couns 65:253-60. 2007..We examined the relationship between patient literacy level and self-reported HIV medication adherence, while estimating the mediating roles of treatment knowledge and self-efficacy on this relationship...
Colorectal cancer screening among African-American and white male veteransNancy C Dolan
Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
Am J Prev Med 28:479-82. 2005..The purpose of this study was to evaluate whether, at a Veterans Affairs (VA) medical center, similar racial/ethnic differences in colorectal cancer screening could be identified...
Development of a brief survey on colon cancer screening knowledge and attitudes among veteransMichael S Wolf
Institute for Health Services Research and Policy Studies, Northwestern University, Feinberg School of Medicine, 676 N St Clair St, Suite 200, Chicago, IL 60611, USA
Prev Chronic Dis 2:A11. 2005..The purpose of this study was to develop a brief assessment tool to evaluate knowledge and attitudes among veterans toward colorectal cancer screening options...
Evaluating the total costs of cancer. The Northwestern University Costs of Cancer ProgramElizabeth A Calhoun
Robert H Lurie Comprehensive, Cancer Center, Institute of Health Services, Health Policy Research, Northwestern University, Medical School, USA
Oncology (Williston Park) 17:109-14; discussion 119-21. 2003..In this article, we outline the theoretical framework associated with a study of cancer costs and summarize findings from our ongoing pilot studies in this area...
A rapid staging system for predicting mortality from HIV-associated community-acquired pneumoniaAhsan M Arozullah
VA Chicago Healthcare System, Westside Division, Department of Medicine, University of Illinois College of Medicine, 60612, USA
Chest 123:1151-60. 2003..Design/setting/patients: Retrospective medical records review of 1,415 patients hospitalized with HIV-associated CAP from 1995 to 1997 at 86 hospitals in seven metropolitan areas...
Clinical features and correlates of gemcitabine-associated lung injury: findings from the RADAR projectSteven M Belknap
Division of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Cancer 106:2051-7. 2006....
A comparison of ovarian cancer treatments: analysis of utility assessments of ovarian cancer patients, at-risk population, general population, and physiciansElizabeth A Calhoun
Obstetrics and Gynecology Gynecologic Oncology, Northwestern University Medical School, Chicago, IL 60611, USA
Gynecol Oncol 93:164-9. 2004..In this study, we elicited assessments of toxicity from women with ovarian cancer, women at increased risk of developing ovarian cancer, women in the general population, and gynecologic oncologists...
Merging claims databases with a tumor registry to evaluate variations in cancer mortality: results from a pilot study of 698 colorectal cancer patients treated at one hospital in the 1990sSimon P Kim
Division of Hematology/Oncology, Northwestern University Medical School, Chicago, Illinois, USA
Cancer Invest 22:225-33. 2004....
Colorectal cancer screening knowledge, attitudes, and beliefs among veterans: does literacy make a difference?Nancy C Dolan
Midwest Center for Health Services and Policy Research, VA Chicago Healthcare System, Department of Medicine, Feinberg School of Medicine, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
J Clin Oncol 22:2617-22. 2004..To evaluate whether lower literacy is associated with poorer knowledge and more negative attitudes and beliefs toward colorectal cancer screening among veterans without recent colorectal cancer screening...
Outcomes and complications associated with off-label and untested use of drug-eluting stentsNirat Beohar
Northwestern University Feinberg School of Medicine, Chicago, Ill, USA
JAMA 297:1992-2000. 2007..Limited data exist regarding use of drug-eluting stents outside of approved indications in real-world settings...
Health care provider-directed intervention to increase colorectal cancer screening among veterans: results of a randomized controlled trialM Rosario Ferreira
Veterans Affairs Midwest Center for Health Services and Policy Research, Hines, USA
J Clin Oncol 23:1548-54. 2005..Colorectal cancer screening is the most underused cancer screening tool in the United States. The purpose of this study was to test whether a health care provider-directed intervention increased colorectal cancer screening rates...
Prediction rule for atrial fibrillation after major noncardiac thoracic surgeryRod S Passman
Northwestern University Feinberg School of Medicine and the Feinberg Cardiovascular Institute, Chicago, Illinois 60611, USA
Ann Thorac Surg 79:1698-703. 2005..We sought to derive and validate a clinical prediction rule to risk-stratify patients for postoperative AF...
Clinical characteristics of erythropoietin-associated pure red cell aplasiaKenneth R Carson
Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine and the Robert H Lurie Comprehensive Cancer Center, Chicago, IL, USA
Best Pract Res Clin Haematol 18:467-72. 2005..Timely identification and treatment of this rare syndrome can prevent the development of severe red blood cell transfusion requirements and the potential complications of iron overload, which results from these transfusions...
Quality of life after a diagnosis of prostate cancer among men of lower socioeconomic status: results from the Veterans Affairs Cancer of the Prostate Outcomes StudyAmy K Siston
Department of Psychiatry and Behavioral Sciences, Northwestern University Medical School, Chicago, Illinois 60611, USA
Urology 61:172-8. 2003..Our study, among the first to assess the QOL at baseline before treatment, provides meaningful information on general treatment effects, which are directly relevant to clinicians when discussing treatment options with patients...
Dissemination of information on potentially fatal adverse drug reactions for cancer drugs from 2000 to 2002: first results from the research on adverse drug events and reports projectLisa A Ladewski
Veterans Affairs Midwest Center for Health and Policy Research, Lakeside Division, Northwestern University Medical Center, Chicago, IL 60611, USA
J Clin Oncol 21:3859-66. 2003..This suggests a need for continued vigilance and efficient strategies for dissemination of information about ADRs associated with cancer drugs...
Epoetin-induced pure red-cell aplasia (PRCA): preliminary results from the research on adverse drug events and reports (RADAR) groupAndrew M Evens
Divison of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center, Chicago, IL 60611, USA
Best Pract Res Clin Haematol 18:481-9. 2005..The decrease in cases occurred coincident with these varied changes, although it is difficult to prove causality. PRCA is a rare, but important side effect of epoetin therapy...
G-CSF as prophylaxis of febrile neutropenia in SCLCJared R Adams
The Chicago Veterans Administration Healthcare System, Lakeside Division, Lakeside VA, 400 E Ontario Ave, IL 60611, USA
Expert Opin Pharmacother 3:1273-81. 2002..CONCLUSIONS: In 2002, the findings of a decade of health services studies have shifted towards not being supportive of CSF use for primary or secondary prophylaxis for SCLC patients...
TTP/HUS occurring in a simultaneous pancreas/kidney transplant recipient after clopidogrel treatment: evidence of a nonimmunological etiologyAndrew M Evens
Department of Internal Medicine--Oncology/Hematology, Lakeside VA, Chicago, IL 60611, USA
Transplantation 74:885-7. 2002..DISCUSSION: Our findings suggest a nonimmunological etiology for TTP/HUS in clopidogrel-treated transplant recipients. Furthermore, mechanistic focused laboratory studies can facilitate interpretation of case report findings...
Racial variations in care and outcomes for inpatient HIV-related pneumocystis pneumoniaJorge P Parada
Health Services Research and Policy, Hines VA Hospital in Hines, Illinois, USA
J Health Care Poor Underserved 21:318-33. 2010..In contrast to the first study, in the second decade African Americans were more likely to receive timely and appropriate therapy for HIV-related PCP, and resultantly were more likely to survive the hospitalization...
Evaluating the supportive care costs of severe radiochemotherapy-induced mucositis and pharyngitis : results from a Northwestern University Costs of Cancer Program pilot study with head and neck and nonsmall cell lung cancer patients who received care at Narissa J Nonzee
Robert H Lurie Comprehensive Cancer Center and Division of Hematology Oncology, Northwestern University, Chicago, Illinois 60611, USA
Cancer 113:1446-52. 2008..Few studies have examined the costs of supportive care for radiochemotherapy-induced mucosits/pharyngitis among patients with head and neck cancer (HNC) or lung cancers despite the documented negative clinical impact of these complications...
Pharmacovigilance and reporting oversight in US FDA fast-track process: bisphosphonates and osteonecrosis of the jawBeatrice J Edwards
Divisions of Hematology Oncology and Geriatric Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL USA
Lancet Oncol 9:1166-72. 2008..Better coordination of safety-related pharmacovigilance initiatives is now needed...
Reassessments of ESAs for cancer treatment in the US and EuropeCharles L Bennett
VA Center for the Management of Complex Chronic Care, VA Chicago Healthcare System, Chicago, Illinois, USA
Oncology (Williston Park) 24:260-8. 2010..In contrast to Europe, where ESA use has increased over time, reassessments of ESA-associated safety concerns in the United States have resulted in marked decrements in ESA use among cancer patients...
Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) projectJune M McKoy
Division of Geriatric Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, 303 E Chicago, Chicago, IL 60611, USA
Leuk Res 31:599-604. 2007....
The blue cross blue shield assessment technology review: summary of findingsCharles L Bennett
Midwest Center for Health Services and Policy Research, and VA Chicago Healthcare Systems Lakeside Division, The Feinberg School of Medicine, Northwestern University, 400 E Ontario Street, Suite 205 Chicago, IL 60611, USA
Best Pract Res Clin Haematol 18:423-31. 2005..An update of this review, which includes information on quality of life, transfusion requirment, survival and tumor response, for first and second-generation epoetin products is ongoing...
Costs and cost effectiveness of a health care provider-directed intervention to promote colorectal cancer screeningVeena Shankaran
Veterans Affairs VA Chicago Healthcare System and VA Center for Management of Complex and Chronic Care, Chicago, IL, USA
J Clin Oncol 27:5370-5. 2009..The objective of this secondary analysis is to assess the cost effectiveness of this intervention...
Cancer-associated neutropenic fever: clinical outcome and economic costs of emergency department careD Mark Courtney
VA Lakeside Medical Center, Division of General Internal Medicine, Department of Medicine, 400 E Ontario Street, Suite 205, Chicago, Illinois 60611, USA
Oncologist 12:1019-26. 2007..Costs of ED care were similar to the cost of a single day of inpatient care. Disclosure of potential conflicts of interest is found at the end of this article...
Health literacy and shared decision making for prostate cancer patients with low socioeconomic statusS P Kim
Division of Hematology/Oncology, Medical School, Chicago, Illinois, USA
Cancer Invest 19:684-91. 2001..The development of shared decision making tools should include collaborative efforts with the target population to improve the success of shared decision making programs among patients with low health literacy...
Quality improvement efforts in oncology: are we ready to begin?C L Bennett
Chicago VA Healthcare System Lakeside Division, Robert H Lurie Comprehensive Cancer Center, Division of Hematology Oncology of Northwestern University, Chicago, Illinois, USA
Cancer Invest 19:86-95. 2001..In this article, we describe the potential benefits and drawbacks of CQI efforts in oncology, review experiences with four different CQI cancer programs, and make recommendations about future CQI efforts...
Growth of oncology physician practice management companiesK Mighion
Robert H Lurie Cancer Center, Institute for Health Services and Policy Research, Northwestern University, Chicago, Illinois, USA
Cancer Invest 17:362-70. 1999..This review article is of broad interest to oncologists practicing in the United States and is meant to provide a useful reference for considering a physician practice management company as a business partner...
Accelerated approval of cancer drugs: improved access to therapeutic breakthroughs or early release of unsafe and ineffective drugs?Elizabeth A Richey
Division of Hematology Oncology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Chicago, IL 60611, USA
J Clin Oncol 27:4398-405. 2009....
Cost considerations in the management of cancer in the older patientJune M McKoy
Division of Geriatrics, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Feinberg School of Medicine, Division of Hematology Oncology, Chicago, Illinois 60611, USA
Oncology (Williston Park) 21:851-7; discussion 858, 860, 862 passim. 2007..Additional research about cancer costs may also lead to reforms in cancer care reimbursement, and therefore provide access to affordable health care for older patients...
HIV-related Pneumocystis carinii pneumonia in older patients hospitalized in the early HAART eraB Kim
Department of Medicine, Northwestern University Medical School, Chicago, Ill, USA
J Gen Intern Med 16:583-9. 2001..Continued vigilance for the possibility of HIV and HIV-related PCP among persons > or =50 years of age who present with new pulmonary symptoms should be encouraged...
Legal, financial, and public health consequences of transfusion-transmitted hepatitis C virus in persons with haemophiliaC Angelotta
Division of Hematology Oncology, Department of Medicine, Northwestern University, Chicago, IL 60611, USA
Vox Sang 93:159-65. 2007..Relatively little attention has been paid to similar hepatitis C virus (HCV) concerns since the first cases of HCV-infected persons with haemophilia were identified in 1989...
Pharmacoeconomics of therapy for ITP: steroids, i.v.Ig, anti-D, and splenectomyJ R Adams
Northwestern University Medical School and the Chicago VA Healthcare System/Lakeside Division, Chicago, IL 60611, USA
Blood Rev 16:65-7. 2002..Thus, in treating patients with ITP, clinical and economic considerations should be considered when choosing among the various treatment options...
US hospital care for patients with HIV infection and pneumonia: the role of public, private, and Veterans Affairs hospitals in the early highly active antiretroviral therapy eraConstance R Uphold
Rehabilitation Outcomes Research Center, North Florida South Georgia Veterans Health System, Research Department, Stop 151, 1601 SW Archer Road, Gainesville, FL 32608 1197, USA
Chest 125:548-56. 2004....
2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guidelineThomas J Smith
American Society of Clinical Oncology, Cancer Policy and Clinical Affairs, Alexandria, VA 22314, USA
J Clin Oncol 24:3187-205. 2006....
When the risk of febrile neutropenia is 20%, prophylactic colony-stimulating factor use is clinically effective, but is it cost-effective?Jared R Adams
J Clin Oncol 24:2975-7. 2006
Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patientsJulia Bohlius
Department of Internal Medicine I, University of Cologne, Germany
J Natl Cancer Inst 98:708-14. 2006..08, 95% CI = 0.99 to 1.18; 42 trials and 8167 patients). Caution is advised when using epoetin or darbepoetin in combination with thrombogenic chemotherapeutic agents or for cancer patients who are at high risk for thrombo-embolic events...
Pilot study of a utilities-based treatment decision intervention for prostate cancer patientsSara J Knight
San Francisco VA Medical Center, Department of Psychiatry, University of California at San Francisco, CA, USA
Clin Prostate Cancer 1:105-14. 2002..Future refinements of both the utility assessment exercise and decision analytic model may be needed before the feasibility of the model in the clinical setting can be determined...
Estimating the cost of cancer: results on the basis of claims data analyses for cancer patients diagnosed with seven types of cancer during 1999 to 2000Stella Chang
Medstat Inc, Washington, DC 20008, USA
J Clin Oncol 22:3524-30. 2004..We derive estimates of the costs of cancer using administrative databases, which include claims and employment-related information on individuals insured by private or Medicare supplemental health plans...
Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Clinical Oncology/American Society of Hematology clinical practice guideline updateJ Douglas Rizzo
Medical College of Wisconsin, Milwaukee, WI, USA
J Clin Oncol 26:132-49. 2008..The guideline was expanded to address use of darbepoetin and thromboembolic risk associated with these agents...
Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guidelineD Andrew Loblaw
American Society of Clinical Oncology, Alexandria, VA 22314, USA
J Clin Oncol 25:1596-605. 2007..To update the 2004 American Society of Clinical Oncology (ASCO) guideline on initial hormonal management of androgen-sensitive, metastatic, recurrent, or progressive prostate cancer (PCa)...
Cancer- and chemotherapy-induced anemiaGeorge M Rodgers
Huntsman Cancer Institute, University of Utah, Utah, USA
J Natl Compr Canc Netw 6:536-64. 2008
Research Grants
- Chicago Cancer Navigation ProjectCharles Bennett; Fiscal Year: 2007..follow-up diagnostic evaluations to improve mean time to a diagnostic resolution between abnormal screening and definitive follow-up for the intervention sites as compared to both previous performance and to the usual care control sites ..
- Chicago Cancer Navigation ProjectCharles Bennett; Fiscal Year: 2007..abstract_text> ..
- Research on Adverse Drug Events and Reports: Novel Multiple Myeloma DrugsCharles Bennett; Fiscal Year: 2007....
