Research Topics
| S M BelknapSummaryAffiliation: Northwestern University Country: USA Publications
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Detail Information
Publications
Quality of methods for assessing and reporting serious adverse events in clinical trials of cancer drugsS M Belknap
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Clin Pharmacol Ther 88:231-6. 2010..The use of a validated tool to describe and assess event type, severity, and causality may lead to more timely, accurate identification of safety signals in cancer treatment...
Application of software design principles and debugging methods to an analgesia prescription reduces risk of severe injury from medical use of opioidsS M Belknap
Division of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Clin Pharmacol Ther 84:385-92. 2008..2.7%, number needed to treat (NNT) = 35, P < 0.015). The widespread diffusion of POPA was associated with a substantial hospitalwide decline in opioid-associated severe/fatal ADEs...
Clinical features and correlates of gemcitabine-associated lung injury: findings from the RADAR projectSteven M Belknap
Division of General Internal Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Cancer 106:2051-7. 2006....
Rituximab-associated hepatitis B virus (HBV) reactivation in lymphoproliferative diseases: meta-analysis and examination of FDA safety reportsA M Evens
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Ann Oncol 22:1170-80. 2011..Rituximab has been associated with hepatitis B virus reactivation (HBV-R). However, the characteristics and scope of this association remain largely undefined...
Evaluation of serious adverse drug reactions: a proactive pharmacovigilance program (RADAR) vs safety activities conducted by the Food and Drug Administration and pharmaceutical manufacturersCharles L Bennett
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Arch Intern Med 167:1041-9. 2007..We compare safety efforts for evaluating serious ADRs conducted by the FDA and pharmaceutical manufacturers vs the RADAR project...
Long-term outcome of individuals with pure red cell aplasia and antierythropoietin antibodies in patients treated with recombinant epoetin: a follow-up report from the Research on Adverse Drug Events and Reports (RADAR) ProjectCharles L Bennett
MidWest Center for Health Services Research and Policy Studies, VA Chicago Healthcare System, Chicago, IL, USA
Blood 106:3343-7. 2005..Reinitiation of epoetin therapy among individuals could be considered if antierythropoietin antibodies are undetectable...
The Research on Adverse Drug Events and Reports (RADAR) projectCharles L Bennett
Jesse Brown VA Medical Center Mid West Center for Health Services and Policy Research, Chicago, Ill 60611, USA
JAMA 293:2131-40. 2005....
Pure red-cell aplasia and epoetin therapyCharles L Bennett
MidWest Center for Health Services Research and Policy Studies, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60611, USA
N Engl J Med 351:1403-8. 2004....
Dissemination of information on potentially fatal adverse drug reactions for cancer drugs from 2000 to 2002: first results from the research on adverse drug events and reports projectLisa A Ladewski
Veterans Affairs Midwest Center for Health and Policy Research, Lakeside Division, Northwestern University Medical Center, Chicago, IL 60611, USA
J Clin Oncol 21:3859-66. 2003..This suggests a need for continued vigilance and efficient strategies for dissemination of information about ADRs associated with cancer drugs...
Serious adverse cutaneous and hepatic toxicities associated with nevirapine use by non-HIV-infected individualsShilpa M Patel
Veterans Affairs Chicago Healthcare System/Lakeside Division, Chicago, IL, USA
J Acquir Immune Defic Syndr 35:120-5. 2004..The rate of severe hepatotoxicity appears to be greater in non-HIV-infected individuals than in HIV-infected persons and may be associated with higher CD4 counts. The use of PEP regimens containing nevirapine should be discouraged...
Adverse drug events in emergency department patientsJohn W Hafner
Department of Emergency Medicine, OSF Saint Francis Medical Center, Peoria, IL 61637, USA
Ann Emerg Med 39:258-67. 2002..Less is known about this common type of injury in emergency department patients. This study seeks to measure the risks, incidence, severity, and costs of ADEs in an ED population...
