- Circadian disruption and metabolic disease: findings from animal modelsDeanna Marie Arble
Center for Sleep and Circadian Biology, Department of Neurobiology and Physiology Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA
Best Pract Res Clin Endocrinol Metab 24:785-800. 2010..Here we review recent key animal studies involving circadian disruption and discuss the possible translational implications of these studies for human health and particularly for the development of metabolic disease...
- Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouseDeanna Marie Arble
Northwestern University, Center for Sleep and Circadian Biology, Evanston, Illinois, United States of America
PLoS ONE 6:e25079. 2011..This study suggests that feeding time can interact with leptin's endogenous rhythm to influence metabolic signals, specifically leading to excessive body weight gains during 'wrongly' timed feeding...