Murad Alam

..Reconstruction of nasal alar defects is difficult because of the complex anatomy of the region. A frequent challenge in this area is repair of small cutaneous defects involving the lateral nasal supratip and the superior alar groove...

..There is little information regarding commonalities, differences, and trends in the regulation of minimally invasive cosmetic procedures (MICP) across different state medical boards in the United States...

..Skin cancer screening and prophylaxis may be of some utility in reducing morbidity and mortality in cardiac transplant patients...

..Patients may delay treatment for skin cancer for various reasons. Prior research on treatment delay has focused on melanoma rather than nonmelanoma skin cancer (NMSC), which is much more common...

..The excellent safety profile is mitigated by the limited efficacy of such procedures...

..There are few data to indicate whether the type of final wound defect is associated with the type of post-Mohs repair...

..With few exceptions, there are management strategies for avoiding laser adverse events, and, if they do occur, for mitigating their impact...

....

..A preponderance of evidence now indicates that storage of reconstituted botulinum toxin solution for longer than the 4 hours recommended by the manufacturer does not result in loss of effectiveness...

..Based on the facial feedback hypothesis, this net change in facial expression may potentially have the secondary effect of reducing the internal experience of negative emotions, thus making patients feel less angry, sad, and fearful...

..To ascertain whether subcuticular epidermal closures of elliptical excisions of the trunk and extremities result in better functional and cosmetic outcomes than simple running epidermal closures of the same sites...

....

..To determine the number of Mohs micrographic surgery (MMS) stages per tumor taken by early- to mid-career Mohs surgeons and to assess other factors affecting number of stages...

..One concern has been that manuscript reviews in which the reviewer is unblinded (e.g. knows author identity) may be biased, with an increased likelihood that the evaluation will not be strictly on scientific merits...

..Vague and inexact word usage can complicate conversations about cutaneous energy devices, especially novel technologies...

..There is patient demand for similar fillers that may be longer lasting...

..This article reviews the indications, efficacy, and adverse effects of brachytherapy in the treatment of nonmelanoma skin cancers...

..Key comparative effectiveness studies are briefly reviewed, and areas of substantial deficiency in such research are highlighted...

..There are no randomized split-face model studies investigating treatments for postinflammatory hyperpigmentation (PIH) in dark skin...

..Dermatofibrosarcoma protuberans (DFSP) is the most common cutaneous sarcoma. Tentacle-like extensions of neoplastic cells create a high incidence of local recurrence and pose challenges to resection and reconstruction...

..While in recent years the number of available procedures has proliferated, there are few objective methods for evaluating the relative quality of these procedures for particular indications or specific patients...

..The authors review the literature to estimate several clinical parameters pertaining to barbed thread suspensions...

..A multitude of soft-tissue fillers exist, each with their own chemical constituents, indications, and effectiveness. It is imperative that plastic surgeons understand these agents when treating patients with cosmetic complaints...

..More experienced surgeons tend to repair larger defects but, possibly because of their increased confidence and skill, rely on less complicated repairs...

..The point of minimal benefit for such laser treatments may lie somewhere between one and three treatments...

..After full-face laser resurfacing of the face, patients often complain of pruritus, which may be intense. It has been suggested that some cases of postresurfacing pruritus may be associated with subclinical fungal infection...

..The fundamental question is whether there is sufficient evidence to support the use of LLLT...

..To assess the comparative efficacy of energy treatments in resolving cherry angiomata...

..There is a lack of randomized split-face studies investigating treatments for dermatosis papulosa nigra (DPN) in dark skin...

..The purpose of this analysis is to critically evaluate what is known about histologic and tissue effects of nonablative laser therapy and suggest future directions for research...

..CONCLUSION: Nonablative treatment with the 1,320 nm Nd:YAG laser induced significant patient-reported improvement in both acne scarring and photoaging. The majority of patients reported satisfaction with the degree of improvement...

..Injectable calcium hydroxylapatite is a soft-tissue augmentation material that is used off-label for facial augmentation, including repletion of depressed nasolabial folds...

..Patients who do experience uncommon, transient effects can be reassured that these are not dangerous and will resolve completely without intervention...

..The purpose of this study was to analyze available datasets to assess the degree of asymmetry typically associated with DFSP, and to study the optimal surgical approach for extirpating these tumors by clearing lateral margins...

..The purpose of this study was to assess the safety of RF treatment over skin areas recently injected with medium-term injectable soft-tissue augmentation materials...

..A rational approach to surgery can increase the comfort and safety of surgery in such patients. Overall, cutaneous surgery is well-tolerated in even the oldest patients...

..However, there are anecdotal reports of treatment-associated discomfort even when purpura is not elicited...

..If patients are treated holistically and comprehensively, their surgical experience can be enhanced and their health and appearance improved...

..In the future, disparate classification schemes may be unified into a single pragmatic approach which accurately reflects the biological process whereby actinic keratoses devolve into invasive squamous cell carcinoma...

..Given the lack of data regarding basic fire safety principles, many dermatologists remain unaware of this potential risk...

..To assess the strength of 2.0 barbed polypropylene suture, and, specifically, to determine the load required to break this suture, and to compare this with the strength of nonbarbed polypropylene suture...

..A variant of the bilobe, the two-lobed flap based on the W-plasty, is a transposition flap that shifts tissue predominantly via advancement...

..Both techniques can result in clinically significant improvements in the appearance of skin and may become increasingly relevant among practitioners as new applications are developed...

..Repeated patient education about skin cancer prevention is important to self-care after transplant...

..Many new devices and therapeutic interventions are continually introduced in cutaneous surgery. The efficacy of these new techniques must be compared with that of preexisting standards so that patients can be appropriately counseled...

..Significant differences observed in therapeutic trials in procedural dermatology are typically denoted by p values of less than .05. Alternatively, significance can be conveyed by use of confidence intervals...

..Pulsed-dye laser treatment has been shown to be highly effective for the treatment of facial telangiectasia. Posttreatment purpura after such treatment has limited patient acceptance of the procedure...

..Deep absorbable stitches should provide a firm closure, hemostasis, and good wound-edge eversion, but this is not always achieved with standard techniques...

..In particular, for each technique, we discuss the method for placement, generally accepted indications, controversies regarding utility, and objective evidence of efficacy...

..In this article, the authors review the management of the few common and minor undesirable effects that may be associated with temporary fillers; in addition, the authors mention the rare incidence of serious complications...

..Laser eye protection has been designed to protect operators and patients from severe eye injuries...

..Antithrombotic medications may increase perioperative bleeding during cutaneous surgery. Whether to discontinue these medications before surgery is controversial...

..EGFR is a transmembrane tyrosine kinase receptor involved in the proliferation and survival of cancer cells. EGFR is the first molecular target against which monoclonal antibodies have been developed for cancer therapy...

..To assess the safety of a novel microneedle device on facial skin of healthy individuals of all Fitzpatrick skin types...

..CONCLUSION: Given appropriate physician management, elderly patients can usually safely undergo cutaneous surgery...

..The authors have indicated no significant interest with commercial supporters...

..Specifically, we examined evidence for the tumor's (1) infectious origin and spread, (2) response to therapy, and (3) prognosis and metastatic risk...

..The unusual unilateral distribution of leiomyomas in this case is discussed...

..Botulinum A exotoxin is used for various indications, including the treatment of dynamic forehead lines...

..Botulinum A exotoxin is a safe agent in common use in dermatology. Occasionally, patients receiving botulinum toxin injections report postprocedure discomfort, including headaches...

..As the first stage of squamous cell carcinoma, actinic keratosis is worthy of prompt evaluation and active treatment...

..To avoid repetitive operations and the risk of recurrence in anatomically sensitive areas, these tumors should be treated with standard wide margins (eg, 4 mm), or have Mohs micrographic surgery for histologic margin control...

..Very large defects (width > 3-5 cm) or those with limited cheek mobility may require flaps or skin grafts for closure...

..In Asians, some conditions such as nevus of Ota are frequently seen and certain adverse reactions, especially postinflammatory hyperpigmentation, tend to be more common...

..CONCLUSIONS: Use of preservative-containing saline to further dilute botulinum toxin type B can significantly decrease patient discomfort on injection...

..05). CONCLUSION: All potential donor sites should be considered to select the donor site that best matches the defect...

..Multiple keratoacanthomas are rarely seen. Keratoacanthomas may also develop after trauma, laser resurfacing, radiation therapy, and at the donor site after skin grafting...

..Treatment of acne scars is a therapeutic challenge that may require multiple modalities. Subcision is a technique that has been anecdotally reported to be of value in treating so-called "rolling scars."..