Research Topics
| M M AbecassisSummaryAffiliation: Northwestern University Country: USA Publications
Research Grants
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Detail Information
Publications
Complications of living donor hepatic lobectomy--a comprehensive reportM M Abecassis
Comprehensive Transplant Center, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Am J Transplant 12:1208-17. 2012..This report comprehensively quantifies LLD complication risk and should inform decision making by potential donors and their caregivers...
Organ acquisition cost centers Part II: reducing the burden of cost and inventoryM Abecassis
Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Transplant 6:2836-40. 2006..This index can be applied retrospectively to any waiting list in order to evaluate how actively the waiting list is being managed. This novel metric can also be used indirectly to assess and monitor waitlist inventory...- Organ acquisition cost centers Part I: medicare regulations--truth or consequenceM Abecassis
Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Transplant 6:2830-5. 2006..We discuss these findings in the context of some basic definitions that refer specifically to cost accounting principles necessary for accurate reporting of OACC... - Transplant center regulations--a mixed blessing? An ASTS Council viewpointM M Abecassis
Northwestern University, Chicago, IL, USA
Am J Transplant 8:2496-502. 2008..This report has been vetted by and represents the opinions of the Council of the ASTS... - American Society of Transplant Surgeons transplant center outcomes requirements--a threat to innovationM M Abecassis
Northwestern University, Chicago, IL, USA
Am J Transplant 9:1279-86. 2009..We propose a methodology that may address this emerging dilemma... - Mycophenolate mofetil and tacrolimus as primary maintenance immunosuppression in simultaneous pancreas-kidney transplantation: initial experience in 50 consecutive casesD B Kaufman
Department of Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
Transplantation 67:586-93. 1999..Quality of graft function, infections, and effect on preexisting essential hypertension are also described... - Perception versus reality?: Virtual crossmatch--how to overcome some of the technical and logistic limitationsA R Tambur
Transplant Immunology Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Am J Transplant 9:1886-93. 2009.... - Mortality in candidates waiting for combined liver-intestine transplants exceeds that for other candidates waiting for liver transplantsJonathan Fryer
Department of Surgery, Northwestern University Medical School, Chicago, IL 60611, USA
Liver Transpl 9:748-53. 2003.... 
Evaluation of 300 minimally invasive liver resections at a single institution: less is moreAlan J Koffron
Division of Transplantation, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Ann Surg 246:385-92; discussion 392-4. 2007..We present the largest, most comprehensive, single center experience to date of minimally invasive liver resection (MILR)...- Laparoscopic liver surgery: Shifting the management of liver tumorsAlan Koffron
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Hepatology 44:1694-700. 2006..We propose that surgical engagement defined by the managing physician's decision to proceed with a surgical intervention is increasingly affected by the availability of, and experience with, laparoscopic liver resection... - Outcomes and native renal recovery following simultaneous liver-kidney transplantationJ Levitsky
Comprehensive Transplant Center, Northwestern University, Chicago, IL Division of Gastroenterology and Hepatology, Northwestern University, Chicago, IL Division of Nephrology, Northwestern University, Chicago, IL Preventive Medicine, Northwestern University, Chicago, IL Department of Radiology, Northwestern University, Chicago, IL Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA
Am J Transplant 12:2949-57. 2012..85, CI 1.22-12.5). Our data support the need to refine SLK selection utilizing more definitive biomarkers and predictors of native renal recovery than current clinical criteria... - Transplant center provision of education and culturally and linguistically competent care: a national studyE J Gordon
Institute for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Am J Transplant 10:2701-7. 2010..Transplant centers need to take greater efforts to consistently provide appropriate education, promote LD, and provide culturally and linguistically competent care to ensure effective communication with all patients... - Patient outcomes and economics of once-daily tacrolimus in renal transplant patients: results of a modeling analysisM M Abecassis
Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Transplant Proc 40:1443-5. 2008.... - Impact of parenteral nutrition-associated liver disease on intestinal transplant waitlist dynamicsNeil Chungfat
Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
J Am Coll Surg 205:755-61. 2007..But United Network for Organ Sharing outcomes reports have not routinely distinguished between the intestine candidate subgroups that are listed only for an intestine and those that are also listed for a liver... - Living donor liver transplantation for hepatocellular carcinomaLaura Kulik
Department of Medicine, Division of Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Gastroenterology 127:S277-82. 2004.... - Financial outcomes in transplantation--a provider's perspectiveM M Abecassis
Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Transplant 6:1257-63. 2006..This minireview will address the essential components of the evaluation of financial outcomes in transplantation... - Risk factors and impact of cytomegalovirus disease in simultaneous pancreas-kidney transplantationD B Kaufman
Department of Surgery, Division of Transplantation, Northwestern University Medical School, Chicago, IL 60611, USA
Transplantation 72:1940-5. 2001..The serological status of the organ donor and the duration of CMV prophylaxis are predictive of who and when CMV disease may occur. Nevertheless, new strategies that reduce risk and severity of CMV disease are still needed... - The economic impact of MELD on liver transplant centersDavid A Axelrod
Division of Transplant Surgery, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Transplant 5:2297-301. 2005..Even with outlier thresholds, Medicare reimbursement is inadequate resulting in a net loss for the TC... - Radiologic-pathologic correlation of hepatocellular carcinoma treated with internal radiation using yttrium-90 microspheresAhsun Riaz
Department of Radiology, Section of Interventional Radiology, Northwestern Memorial Hospital, Chicago, IL, USA
Hepatology 49:1185-93. 2009..CONCLUSION: Post-radioembolization imaging findings of response by EASL and WHO criteria are predictive of the degree of pathologic necrosis. Rim enhancement was an imaging characteristic that correlated well with histologic necrosis... - Living donor liver transplant for malignancyDavid Axelrod
Division of Transplant Surgery, Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Transplantation 79:363-6. 2005..However, HCC patients with large tumors experience a high rate of recurrence. The use of ALDLT for cholangiocarcinoma appears promising specifically in the context of neo-adjuvant therapy... - Preoperative evaluation of the entire hepatic vasculature in living liver donors with use of contrast-enhanced MR angiography and true fast imaging with steady-state precessionJames C Carr
Department of Radiology, Northwestern University Medical School, 251 East Huron Street, Feinberg 4 710, Chicago, Illinois 60611, USA
J Vasc Interv Radiol 14:441-9. 2003..To preoperatively assess the entire hepatic vasculature in living related liver donors with use of a combination of contrast material-enhanced magnetic resonance (MR) angiography and true fast imaging with steady-state precession (FISP)... - Radioembolization for hepatocellular carcinoma using Yttrium-90 microspheres: a comprehensive report of long-term outcomesRiad Salem
Section of Interventional Radiology, Department of Radiology, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA
Gastroenterology 138:52-64. 2010..Hepatocellular carcinoma (HCC) has limited treatment options; long-term outcomes following intra-arterial radiation are unknown. We assessed clinical outcomes of patients treated with intra-arterial yttrium-90 microspheres (Y90)... - Alpha-fetoprotein response after locoregional therapy for hepatocellular carcinoma: oncologic marker of radiologic response, progression, and survivalAhsun Riaz
Department of Radiology, Section of Interventional Radiology, Northwestern Memorial Hospital, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
J Clin Oncol 27:5734-42. 2009..We present a novel correlation of AFP response to radiologic response, time-to-progression (TTP), progression-free survival (PFS), and overall survival (OS) in patients treated with locoregional therapies... - Imaging response in the primary index lesion and clinical outcomes following transarterial locoregional therapy for hepatocellular carcinomaAhsun Riaz
Department of Radiology, Northwestern Memorial Hospital, Robert H Lurie Comprehensive Cancer Center, Chicago, IL, USA
JAMA 303:1062-9. 2010..No universally accepted standard exists... - Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosisLaura M Kulik
Department of Hepatology, Northwestern University, Chicago, IL, USA
Hepatology 47:71-81. 2008..Further investigation is warranted in patients with main PVT... - Intrahepatic biliary cystadenoma: role of cyst fluid analysis and surgical management in the laparoscopic eraAlan Koffron
Department of Surgery, Northwestern University Medical School, Chicago, IL, USA
Surgery 136:926-36. 2004..CONCLUSIONS: We have proposed a management algorithm for IBC that incorporates CFA and laproscopic surgical management that allows for selective minimally invasive cyst wall sampling for patients with IBC... - Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agentsJosh Levitsky
Division of Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Hum Immunol 70:146-50. 2009..However, TAC patients may have other regulatory characteristics, supporting the need for larger, prospective studies to clarify differences... - Hemodynamic evaluation before liver transplantation: insights into the portal hypertensive syndromeAndres T Blei
Division of Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
J Clin Gastroenterol 41:S323-9. 2007..A lower sensitivity of noninvasive screening tools for the detection of coronary atherosclerosis is likely the result of the interaction of the hyperdynamic circulation with the performance of these tests... - ACE gene D/D genotype as a risk factor for chronic nephrotoxicity from calcineurin inhibitors in liver transplant recipientsLorenzo Gallon
Department of Medicine, Division of Nephrology, Northwestern University, Chicago, IL 60611, USA
Transplantation 81:463-8. 2006..The activation of the renin angiotensin system (RAS) has been implicated in the pathogenesis of chronic nephrotoxicity from CI... - Frequency and significance of acute heart failure following liver transplantationMicah J Eimer
Department of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Am J Cardiol 101:242-4. 2008..This study suggests that those patients with preoperative elevated right-sided cardiac pressures, as well as older patients, may be at excess risk for developing HF after transplantation... - Split liver sharing in the United StatesMichael Abecassis
Am J Transplant 5:1583-4. 2005 - Laparoscopic liver resectionJoseph F Buell
Division of Transplantation, The University of Cincinnati, Cincinnati, OH 45267-0558, USA
J Am Coll Surg 200:472-80. 2005 - Multicenter, randomized study of the use of everolimus with tacrolimus after renal transplantation demonstrates its effectivenessLaurence Chan
Health Sciences Center, University of Colorado, Denver, CO 80262, USA
Transplantation 85:821-6. 2008..Clinical data are lacking concerning concomitant administration of everolimus and tacrolimus in renal transplant recipients... - TNF receptor independent activation of the cytomegalovirus major immediate early enhancer in response to transplantationZheng Zhang
Transplant Division, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Transplantation 85:1039-45. 2008..We have used TNF receptor-deficient MIEP-lacZ (MIEP-lacZ TNFR DKO) mice to study the requirement for TNF in transplant-induced activation of the MIEP... - Renal ischemia/reperfusion injury activates the enhancer domain of the human cytomegalovirus major immediate early promoterSoo Jung Kim
Department of Surgery, Transplant Lab, Northwestern University, Chicago, IL 60611, USA
Am J Transplant 5:1606-13. 2005..This likely occurs through ROS-mediated activation of AP-1. Targeting MAP kinase signaling pathways as well as NF-kappaB may be of therapeutic value in patients with CMV infection... - Safety, tolerability, and efficacy of everolimus in de novo liver transplant recipients: 12- and 36-month resultsGary Levy
Multiorgan Transplantation, Toronto General Hospital, Toronto, Ontario, Canada
Liver Transpl 12:1640-8. 2006..In conclusion, this study demonstrates that everolimus in combination with oral cyclosporine had an acceptable safety and tolerability profile, paving the way for additional studies in this transplant indication... - Establishment of murine cytomegalovirus latency in vivo is associated with changes in histone modifications and recruitment of transcriptional repressors to the major immediate-early promoterXue Feng Liu
Department of Surgery, Transplant Division, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Virol 82:10922-31. 2008....
Research Grants
- Adult Live Donor Liver Transplant-A Comparative AnalysisMichael Abecassis; Fiscal Year: 2007..abstract_text> ..
- Transplant Surgery Scientist Training ProgramMichael Abecassis; Fiscal Year: 2007..The initiation of the program comes at a time of substantial growth in the Northwestern University Feinberg School of Medicine, thus making this an ideal site for this T32 NRSA award for research in transplant surgery sciences. ..
- SURGICAL STUDIES OF CMV REACTIVATION IN TRANSPLANTATIONMichael Abecassis; Fiscal Year: 2007....
- SURGICAL STUDIES OF CMV REACTIVATION IN TRANSPLANTATIONMichael Abecassis; Fiscal Year: 2002....