Affiliation: Northeastern University
- Novel powder formulations for controlled delivery of poorly soluble anticancer drug: application and investigation of TPGS and PEG in spray-dried particulate systemLi Mu
Division of Bioengineering, National University of Singapore, 9 Engineering Drive 1, 117576, Singapore
J Control Release 103:565-75. 2005..The combination of PLGA/TPGS/PEG as safe pharmaceutical excipient to formulate particulate delivery system is beneficial in improving the pharmaceutical properties for further powder dosage application...
- Application of TPGS in polymeric nanoparticulate drug delivery systemL Mu
Division of Bioengineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore
Colloids Surf B Biointerfaces 47:90-7. 2006..The results also demonstrate that the drug incorporation capability and the release characteristics of drug-loaded nanoparticles can be influenced by surfactant stabiliser...
- Fabrication, characterization and in vitro release of paclitaxel (Taxol) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiersL Mu
Institute of Materials Research and Engineering, 3 Research Link, 117602, Singapore, Singapore
J Control Release 76:239-54. 2001..The release rate then gradually decreased. The microspheres fabricated with high ratio of DPPC exhibited large initial burst. When cholesterol was combined together with DPPC as an emulsifier, the release became faster...
- A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGSL Mu
Division of Bioengineering, The National University of Singapore, 9 Engineering Drive 1, 117576, Singapore, Singapore
J Control Release 86:33-48. 2003..Nanoparticles of nanometer size with narrow distribution can be obtained. A drug encapsulation efficiency as high as 100% can be achieved and the release kinetics can be controlled...
- Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol)L Mu
Division of Bioengineering, The National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260, Singapore
J Control Release 80:129-44. 2002..Our research shows that vitamin E TPGS could be an ideal and effective emulsifier...
- PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratioLi Mu
Division of Bioengineering, The National University of Singapore, 9 Engineering Drive 1, Singapore 117576
Pharm Res 20:1864-72. 2003..Among various controlling parameters in the process, the present work is to elucidate the effects of the surfactant stabilizer and the drug loading ratio...
- Nanoparticles of biodegradable polymers for clinical administration of paclitaxelSi Shen Feng
Division of Bioengineering, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260
Curr Med Chem 11:413-24. 2004....
- Mn-doped zinc aluminate nanoparticles: hydrothermal synthesis, characterization, and photoluminescence propertiesLi Mu
Hefei National Laboratory for Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, Hefei 230026, P R China
J Nanosci Nanotechnol 6:863-7. 2006..Compared with the bulk sample, the PL spectrum of Mn-doped ZnAl2O4 nanoparticles has distinct blue shift. This procedure provides a facile way for the synthesis of well-crystallized ZnAl2O4:Mn at low temperature...
- A smart surface in a microfluidic chip for controlled protein separationLi Mu
Chemistry Department and Institutes of Biomedical Sciences, Fudan University, 220 Handan Rd, Shanghai 200433, P R China
Chemistry 13:5113-20. 2007..For the latter mixture, the resulting separation efficiency indicated that the molar ratio of avidin and streptavidin could be increased from 1:1000 to about 32:1 after five run separations...