Research Topics
Genomes and GenesSpecies | Valentin A IlyinSummaryAffiliation: Northeastern University Country: USA Publications
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Detail Information
Publications
Structural alignment of proteins by a novel TOPOFIT method, as a superimposition of common volumes at a topomax pointValentin A Ilyin
Biology Department, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
Protein Sci 13:1865-74. 2004..The TOPOFIT method also helps to detect conformational changes, topological differences in variable parts, which are particularly important for studies of variations in active/ binding sites and protein classification...
ModView, visualization of multiple protein sequences and structuresValentin A Ilyin
The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Bioinformatics 19:165-6. 2003..ModView is also suitable as a graphical interface to various databases because it can be controlled through JavaScript commands and called from CGI scripts. AVAILABILITY: ModView is available at http://guitar.rockefeller.edu/modview...
Friend, an integrated analytical front-end application for bioinformaticsAlexej Abyzov
Department of Biology, Northeastern University, Boston, MA, USA
Bioinformatics 21:3677-8. 2005..The application is linked and communicates with local and remote sequence and structure databases. AVAILABILITY: http://mozart.bio.neu.edu/friend...
MODBASE, a database of annotated comparative protein structure modelsUrsula Pieper
Laboratories of Molecular Biophysics, The Pels Family Center for Biochemistry and Structural Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Nucleic Acids Res 30:255-9. 2002....
A comprehensive analysis of non-sequential alignments between all protein structuresAlexej Abyzov
Department of Biology, Northeastern University 360 Huntington Avenue, Boston, MA 02115, USA
BMC Struct Biol 7:78. 2007..We present here a comprehensive large-scale study of non-sequential alignments between available protein structures in Protein Data Bank...
Structural exon database, SEDB, mapping exon boundaries on multiple protein structuresChesley M Leslin
Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
Bioinformatics 20:1801-3. 2004..AVAILABILITY: SEDB is publicly available at http://glinka.bio.neu.edu/SEDB/SEDB.html SUPPLEMENTARY INFORMATION: On the SEDB Web site...
LigBase: a database of families of aligned ligand binding sites in known protein sequences and structuresAshley C Stuart
Laboratories of Molecular Biophysics, Pels Family Center for Biochemistry and Structural Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Bioinformatics 18:200-1. 2002..Residues in the binding sites are graphically depicted for comparison with other structurally defined family members. LigBase provides a resource for the analysis of families of related binding sites...
TOPOFIT-DB, a database of protein structural alignments based on the TOPOFIT methodChesley M Leslin
Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
Nucleic Acids Res 35:D317-21. 2007..T-DB presents researchers with the opportunity for comprehensive studies of the variability in proteins and is publicly available at http://mozart.bio.neu.edu/topofit/index.php...
An AP endonuclease 1-DNA polymerase beta complex: theoretical prediction of interacting surfacesAlexej Abyzov
Department of Biology, Northeastern University, Boston, Massachusetts, United States of America
PLoS Comput Biol 4:e1000066. 2008..The method described here can be used for analysis in any DNA-metabolizing pathway where weak interactions are the principal mode of cross-talk among participants and co-crystal structures of the individual components are available...
Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesisAlper Uzun
Department of Biology, Northeastern University, Boston, MA, USA
BMC Genomics 10:183. 2009..The objectives of this study were to determine transcript abundance of HMGN3a and SMARCAL1 in mature bovine oocytes and early bovine embryos, to perform comparative functional genomics analysis of these genes across mammals...
Tools for comparative protein structure modeling and analysisNarayanan Eswar
Department of Biopharmaceutical Sciences and California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94143-2240, USA
Nucleic Acids Res 31:3375-80. 2003....
