M Febo

Summary

Affiliation: Northeastern University
Country: USA

Publications

  1. pmc Imaging the neural circuitry and chemical control of aggressive motivation
    Craig F Ferris
    Center for Translational Neuroimaging, Northeastern University, Boston, Massachusetts, USA
    BMC Neurosci 9:111. 2008
  2. ncbi request reprint Nursing stimulation is more than tactile sensation: It is a multisensory experience
    Marcelo Febo
    Department of Psychology, Northeastern University, 360 Huntington Avenue 125NI, Boston, MA 02115, USA
    Horm Behav 54:330-9. 2008
  3. pmc Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing
    M Febo
    Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Neuroscience 148:400-12. 2007
  4. pmc Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate
    Marcelo Febo
    Department of Psychology and Center for Translational Neuroimaging, Northeastern University, Boston, MA, USA
    Neurosci Lett 465:267-71. 2009
  5. pmc Inactivation or inhibition of neuronal activity in the medial prefrontal cortex largely reduces pup retrieval and grouping in maternal rats
    Marcelo Febo
    Department of Psychology, Northeastern University, Boston, Massachusetts 02115, USA
    Brain Res 1325:77-88. 2010
  6. pmc Prefrontal cell firing in male rats during approach towards sexually receptive female: interactions with cocaine
    Marcelo Febo
    Department of Psychology, Northeastern University, Boston, Massachusetts 02115, USA
    Synapse 65:271-7. 2011
  7. pmc BOLD signal response to cocaine varies with sexual receptivity in female rats
    Marcelo Febo
    Center for Translational Neuroimaging, Northeastern University, Boston, Massachusetts, USA
    Neuroreport 22:19-22. 2011
  8. pmc Increased BOLD activation to predator stressor in subiculum and midbrain of amphetamine-sensitized maternal rats
    Marcelo Febo
    Department of Psychology, Northeastern University, Boston, MA 02115, USA
    Brain Res 1382:118-27. 2011
  9. ncbi request reprint Pup suckling is more rewarding than cocaine: evidence from functional magnetic resonance imaging and three-dimensional computational analysis
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:149-56. 2005
  10. pmc Blood oxygen level-dependent signal responses in corticolimbic 'emotions' circuitry of lactating rats facing intruder threat to pups
    Benjamin C Nephew
    Department of Psychology and Center for Translational Neuroimaging, Northeastern University, Boston, MA 02115, USA
    Eur J Neurosci 30:934-45. 2009

Research Grants

  1. Brain Imaging of Cocaine and Maternal Reward
    Marcelo Febo; Fiscal Year: 2007
  2. Brain Imaging of Cocaine and Maternal Reward
    Marcelo Febo; Fiscal Year: 2009
  3. Brain Imaging of Cocaine and Maternal Reward
    Marcelo Febo; Fiscal Year: 2010

Detail Information

Publications23

  1. pmc Imaging the neural circuitry and chemical control of aggressive motivation
    Craig F Ferris
    Center for Translational Neuroimaging, Northeastern University, Boston, Massachusetts, USA
    BMC Neurosci 9:111. 2008
    ....
  2. ncbi request reprint Nursing stimulation is more than tactile sensation: It is a multisensory experience
    Marcelo Febo
    Department of Psychology, Northeastern University, 360 Huntington Avenue 125NI, Boston, MA 02115, USA
    Horm Behav 54:330-9. 2008
    ..Enhanced sensitivity across the cortical mantle during nursing may help the dam to perceive, process, and remember stimuli critical to the care and protection of her young...
  3. pmc Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing
    M Febo
    Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Neuroscience 148:400-12. 2007
    ..Changes in retrieval behavior in cocaine-sensitized mothers might be associated with a hypo-responsive medial PFC...
  4. pmc Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate
    Marcelo Febo
    Department of Psychology and Center for Translational Neuroimaging, Northeastern University, Boston, MA, USA
    Neurosci Lett 465:267-71. 2009
    ..These findings suggest that HDACi modulation after repeated stimulant exposure involves cortico-limbic circuitry regulating emotion, motivation and memory...
  5. pmc Inactivation or inhibition of neuronal activity in the medial prefrontal cortex largely reduces pup retrieval and grouping in maternal rats
    Marcelo Febo
    Department of Psychology, Northeastern University, Boston, Massachusetts 02115, USA
    Brain Res 1325:77-88. 2010
    ..External factors that affect the function of the frontal cortical site may result in significant impairments in maternal goal-directed behavior as reported in our earlier work...
  6. pmc Prefrontal cell firing in male rats during approach towards sexually receptive female: interactions with cocaine
    Marcelo Febo
    Department of Psychology, Northeastern University, Boston, Massachusetts 02115, USA
    Synapse 65:271-7. 2011
    ..The present results provide preliminary evidence for neurons in the mPFC that are involved in sexually motivated approach behavior and that are modulated by cocaine...
  7. pmc BOLD signal response to cocaine varies with sexual receptivity in female rats
    Marcelo Febo
    Center for Translational Neuroimaging, Northeastern University, Boston, Massachusetts, USA
    Neuroreport 22:19-22. 2011
    ..Our data suggest that the differential sensitivity to cocaine occurs not only as a result of hormonal changes of the estrous cycle, but also in association with changes in sexual receptivity...
  8. pmc Increased BOLD activation to predator stressor in subiculum and midbrain of amphetamine-sensitized maternal rats
    Marcelo Febo
    Department of Psychology, Northeastern University, Boston, MA 02115, USA
    Brain Res 1382:118-27. 2011
    ..The greater responsiveness of these two brain regions following stimulant sensitization might impact neural processing in response to stressors in the maternal brain...
  9. ncbi request reprint Pup suckling is more rewarding than cocaine: evidence from functional magnetic resonance imaging and three-dimensional computational analysis
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:149-56. 2005
    ..These data support the notion that pup stimulation is more reinforcing than cocaine, underscoring the importance of pup seeking over other rewarding stimuli during lactation...
  10. pmc Blood oxygen level-dependent signal responses in corticolimbic 'emotions' circuitry of lactating rats facing intruder threat to pups
    Benjamin C Nephew
    Department of Psychology and Center for Translational Neuroimaging, Northeastern University, Boston, MA 02115, USA
    Eur J Neurosci 30:934-45. 2009
    ..This pattern of blood oxygen level-dependent activity may precede behavioral states upon which lactating rats initiate attacks against a potential threat to offspring...
  11. pmc Central vasopressin V1a receptors modulate neural processing in mothers facing intruder threat to pups
    Martha K Caffrey
    Department of Psychology, Northeastern University, Boston, Massachusetts 02115 5000, USA
    Neuropharmacology 58:107-16. 2010
    ....
  12. doi request reprint Effect of cocaine sensitization prior to pregnancy on maternal care and aggression in the rat
    Benjamin C Nephew
    Department of Psychology, Northeastern University, Boston, MA 02115, USA
    Psychopharmacology (Berl) 209:127-35. 2010
    ..Although many studies have investigated the effects of gestational and lactational cocaine use on maternal behavior, few studies have examined the effects of prior adult cocaine use on maternal behavior...
  13. pmc Functional magnetic resonance imaging in conscious animals: a new tool in behavioural neuroscience research
    C F Ferris
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Neuroendocrinol 18:307-18. 2006
  14. pmc Imaging cocaine-induced changes in the mesocorticolimbic dopaminergic system of conscious rats
    Marcelo Febo
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, CCNI Building, 303 Belmont Street, Worcester, MA 01655, USA
    J Neurosci Methods 139:167-76. 2004
    ..These findings demonstrate the technical feasibility of studying psychostimulant-induced brain activity using functional MRI in conscious rats...
  15. ncbi request reprint Oxytocin modulates unconditioned fear response in lactating dams: an fMRI study
    Marcelo Febo
    Center for Translational Neuroimaging and Department of Psychology, Northeastern University, Boston, MA, USA
    Brain Res 1302:183-93. 2009
    ....
  16. pmc A bold view of the lactating brain: functional magnetic resonance imaging studies of suckling in awake dams
    M Febo
    Department of Psychiatry, The McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL 32610 0256, USA
    J Neuroendocrinol 23:1009-19. 2011
    ..Our ongoing fMRI studies support and extend past research on the maternal rat brain and its functional neurocircuitry...
  17. ncbi request reprint Functional magnetic resonance imaging shows oxytocin activates brain regions associated with mother-pup bonding during suckling
    Marcelo Febo
    Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:11637-44. 2005
    ..The data suggest that oxytocin may strengthen mother-infant bond formation partly by acting through brain areas involved in regulating olfactory discrimination, emotions, and reward...
  18. pmc Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI
    Karl F Schmidt
    Center for Comparative NeuroImaging, University of Massachusetts, Worcester, MA, USA
    Psychopharmacology (Berl) 185:479-86. 2006
    ....
  19. ncbi request reprint Estrogen influences cocaine-induced blood oxygen level-dependent signal changes in female rats
    Marcelo Febo
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:1132-6. 2005
    ..It is possible that the actions of estrogen within the aforementioned brain regions potentiate the behavioral response to cocaine observed in female rats...
  20. pmc The neural consequences of repeated cocaine exposure revealed by functional MRI in awake rats
    Marcelo Febo
    Psychiatry Department, Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Neuropsychopharmacology 30:936-43. 2005
    ..Therefore, the lower metabolic activation in response to cocaine could reflect a reduced neuronal and/or synaptic activity upon repeated administration...
  21. ncbi request reprint Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats
    Marcelo Febo
    Laboratory of Neuroendocrinology, Department of Physiology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico
    J Neurochem 86:405-12. 2003
    ..These data suggest that changes in D2/D3 receptor function represent one mechanism by which estrogen regulates behavioral sensitization to cocaine...
  22. ncbi request reprint Cocaine alters GABA(B)-mediated G-protein activation in the ventral tegmental area of female rats: modulation by estrogen
    Marcelo Febo
    Laboratory of Neuroendocrinology, Department of Physiology andZ Biophysics, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico 00936 5067
    Synapse 54:30-6. 2004
    ..Thus, our data suggest that estrogen reduces GABA(B)-mediated G-protein activation in female rats. The results also show that estrogen strongly influences cocaine-induced alterations in GABA(B) function in the VTA and EC of female rats...
  23. ncbi request reprint Estrogen and opioids interact to modulate the locomotor response to cocaine in the female rat
    Marcelo Febo
    Department of Physiology, School of Medicine, University of Puerto Rico, PO Box 365067, San Juan, PR 00936, USA
    Brain Res 943:151-61. 2002
    ..In addition in the female, the effect of opioids on cocaine-induced locomotor behavior is dependent on plasma levels of estrogen...

Research Grants4

  1. Brain Imaging of Cocaine and Maternal Reward
    Marcelo Febo; Fiscal Year: 2007
    ....
  2. Brain Imaging of Cocaine and Maternal Reward
    Marcelo Febo; Fiscal Year: 2009
    ....
  3. Brain Imaging of Cocaine and Maternal Reward
    Marcelo Febo; Fiscal Year: 2010
    ....