J J Docherty

Summary

Affiliation: Northeastern Ohio Universities College of Medicine
Country: USA

Publications

  1. ncbi request reprint Resveratrol inhibition of herpes simplex virus replication
    J J Docherty
    Department of Microbiology and Immunology, Northeastern Ohio Universities College of Medicine, Rootstown 44272, USA
    Antiviral Res 43:145-55. 1999
  2. ncbi request reprint Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice
    John J Docherty
    Department of Microbiology Immunology, Northeastern Ohio Universities, College of Medicine, PO Box 95, State Route 44, Rootstown, OH 44272, USA
    Antiviral Res 61:19-26. 2004
  3. ncbi request reprint Effect of resveratrol on herpes simplex virus vaginal infection in the mouse
    John J Docherty
    Department of Microbiology Immunology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, Rootstown, OH 44272, USA
    Antiviral Res 67:155-62. 2005
  4. ncbi request reprint Resveratrol inhibition of varicella-zoster virus replication in vitro
    John J Docherty
    Northeastern Ohio Universities College of Medicine, P O Box 95, Rootstown, OH 44272, USA
    Antiviral Res 72:171-7. 2006
  5. ncbi request reprint Resveratrol inhibition of Propionibacterium acnes
    John J Docherty
    Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH 44272, USA
    J Antimicrob Chemother 59:1182-4. 2007
  6. ncbi request reprint Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells
    Seth A Faith
    Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH 44272, USA
    Antiviral Res 72:242-51. 2006
  7. ncbi request reprint The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potential
    N Goel
    Northeastern Ohio Universities College of Medicine, Rootstown 44272, USA
    Arch Virol 147:763-73. 2002
  8. ncbi request reprint A modification of the epidermal scarification model of herpes simplex virus infection to achieve a reproducible and uniform progression of disease
    Neena Goel
    Department of Microbiology Immunology, Northeastern Ohio Universities, College of Medicine, 4209 State Route 44, Box 95, Rootstown, OH 44272, USA
    J Virol Methods 106:153-8. 2002
  9. ncbi request reprint Innate and adaptive host response during the initial phase of herpes simplex virus encephalitis in the neonatal mouse
    Guttalu K Kumaraswamy
    Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272, USA
    J Neurovirol 12:365-74. 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Resveratrol inhibition of herpes simplex virus replication
    J J Docherty
    Department of Microbiology and Immunology, Northeastern Ohio Universities College of Medicine, Rootstown 44272, USA
    Antiviral Res 43:145-55. 1999
    ..These results suggest that a critical early event in the viral replication cycle, that has a compensatory cellular counterpart, is being adversely affected...
  2. ncbi request reprint Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice
    John J Docherty
    Department of Microbiology Immunology, Northeastern Ohio Universities, College of Medicine, PO Box 95, State Route 44, Rootstown, OH 44272, USA
    Antiviral Res 61:19-26. 2004
    ..These studies demonstrate that topically applied resveratrol inhibits HSV lesion formation in the skin of mice...
  3. ncbi request reprint Effect of resveratrol on herpes simplex virus vaginal infection in the mouse
    John J Docherty
    Department of Microbiology Immunology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, Rootstown, OH 44272, USA
    Antiviral Res 67:155-62. 2005
    ..5% resveratrol-treated animals was 24%, and 19% resveratrol-treated animals was 3%. Collectively, these results demonstrate that resveratrol cream inhibits or reduces HSV replication in the vagina of mice and limits extravaginal disease...
  4. ncbi request reprint Resveratrol inhibition of varicella-zoster virus replication in vitro
    John J Docherty
    Northeastern Ohio Universities College of Medicine, P O Box 95, Rootstown, OH 44272, USA
    Antiviral Res 72:171-7. 2006
    ..These results demonstrate that VZV replication is adversely affected by resveratrol which is negatively impacting IE62 synthesis...
  5. ncbi request reprint Resveratrol inhibition of Propionibacterium acnes
    John J Docherty
    Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH 44272, USA
    J Antimicrob Chemother 59:1182-4. 2007
    ..To evaluate the effects of the anti-inflammatory hydroxystilbene, resveratrol, on Propionibacterium acnes growth...
  6. ncbi request reprint Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells
    Seth A Faith
    Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH 44272, USA
    Antiviral Res 72:242-51. 2006
    ..Cumulatively, these data indicate that resveratrol (i) suppresses HSV induced activation of NF-kappaB within the nucleus and (ii) impairs expression of essential immediate-early, early and late HSV genes and synthesis of viral DNA...
  7. ncbi request reprint The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potential
    N Goel
    Northeastern Ohio Universities College of Medicine, Rootstown 44272, USA
    Arch Virol 147:763-73. 2002
    ..In conclusion, the viral properties which are important for neuroinvasiveness appear to also determine the ability of an HSV strain to cause zosteriform disease...
  8. ncbi request reprint A modification of the epidermal scarification model of herpes simplex virus infection to achieve a reproducible and uniform progression of disease
    Neena Goel
    Department of Microbiology Immunology, Northeastern Ohio Universities, College of Medicine, 4209 State Route 44, Box 95, Rootstown, OH 44272, USA
    J Virol Methods 106:153-8. 2002
    ....
  9. ncbi request reprint Innate and adaptive host response during the initial phase of herpes simplex virus encephalitis in the neonatal mouse
    Guttalu K Kumaraswamy
    Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272, USA
    J Neurovirol 12:365-74. 2006
    ..B and T lymphocytes were not detected on day 1 through 7 post infection. This controlled experimental HSV infection suggests a limited non-specific early host response in the neonate to HSV encephalitis...