Research Topics
| J W DevlinSummaryAffiliation: Northeastern University Country: USA Publications
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Detail Information
Publications
Delirium assessment in the critically illJohn W Devlin
Northeastern University School of Pharmacy, 360 Huntington Ave, Boston, MA 02115 5000, USA
Intensive Care Med 33:929-40. 2007..To compare available instruments for assessing delirium in critically ill adults that have undergone validity testing and provide clinicians with strategies to incorporate these instruments into clinical practice...- Pharmacologic prevention and treatment of delirium in critically ill and non-critically ill hospitalised patients: A review of data from prospective, randomised studiesJohn W Devlin
Northeastern University School of Pharmacy, 360 Huntington Ave R218 TF, Boston, MA 02118, USA Electronic address
Best Pract Res Clin Anaesthesiol 26:289-309. 2012..A research framework for future evaluation of the use of medications in both ICU and non-ICU is proposed... - Optimising the recognition of delirium in the intensive care unitJohn W Devlin
Northeastern University School of Pharmacy, 360 Huntington Ave, R218 TF, Boston, MA 02118, USA Electronic address
Best Pract Res Clin Anaesthesiol 26:385-93. 2012.... - Impact of quetiapine on resolution of individual delirium symptoms in critically ill patients with delirium: a post-hoc analysis of a double-blind, randomized, placebo-controlled studyJohn W Devlin
Northeastern University School of Pharmacy, 360 Huntington Avenue, Mugar 206, Boston, MA 02115, USA
Crit Care 15:R215. 2011.... - Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter studyRussel J Roberts
Department of Pharmacy, Tufts Medical Center, Boston, MA 02111, USA
Crit Care 13:R169. 2009..This prospective, multicenter study sought to determine the incidence of PRIS and PRIS-related clinical manifestations in a large cohort of critically ill adults prescribed propofol... - Patterns of antihypertensive treatment in patients with acute severe hypertension from a nonneurologic cause: Studying the Treatment of Acute Hypertension (STAT) registryJohn W Devlin
Northeastern University School of Pharmacy, Boston, Massachusetts 02115, USA
Pharmacotherapy 30:1087-96. 2010..To assess antihypertensive treatment practices and outcomes for patients with acute severe hypertension requiring hospitalization... - Use of a validated delirium assessment tool improves the ability of physicians to identify delirium in medical intensive care unit patientsJohn W Devlin
Northeastern University School of Pharmacy, Northeastern University, Boston, MA, USA
Crit Care Med 35:2721-4; quiz 2725. 2007..We sought to measure the effect of physicians' use of the ICDSC on their ability to detect delirium... - Combined didactic and scenario-based education improves the ability of intensive care unit staff to recognize delirium at the bedsideJohn W Devlin
School of Pharmacy, Northeastern University, 360 Huntington Avenue, Boston, MA 02118, USA
Crit Care 12:R19. 2008..We sought to measure the impact of a simple educational intervention on the ability of intensive care unit (ICU) nurses to clinically identify delirium and to use a standardized delirium scale correctly... - The pharmacology of oversedation in mechanically ventilated adultsJohn W Devlin
Northeastern University School of Pharmacy, Boston, Massachusetts 02115, USA
Curr Opin Crit Care 14:403-7. 2008..To review pharmacological-related factors that affect the incidence of oversedation in mechanically ventilated adults... - Pharmacology of commonly used analgesics and sedatives in the ICU: benzodiazepines, propofol, and opioidsJohn W Devlin
Northeastern University School of Pharmacy, MU206, 360 Huntington Avenue, Boston, MA 02115, USA
Crit Care Clin 25:431-49, vii. 2009..To optimize care, critical care clinicians should be familiar with the many pharmacokinetic, pharmacodynamic, and pharmacogenetic variables that can affect the safety and efficacy of these sedatives and analgesics... - Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot studyJohn W Devlin
Northeastern University School of Pharmacy, Boston, MA, USA
Crit Care Med 38:419-27. 2010..To compare the efficacy and safety of scheduled quetiapine to placebo for the treatment of delirium in critically ill patients requiring as-needed haloperidol... - Adverse drug events associated with the use of analgesics, sedatives, and antipsychotics in the intensive care unitJohn W Devlin
School of Pharmacy, Northeastern University, Boston, MA, USA
Crit Care Med 38:S231-43. 2010.... - Antipsychotics for the prevention and treatment of delirium in the intensive care unit: what is their role?John W Devlin
Northeastern University School of Pharmacy, Boston, MA 02115, USA
Harv Rev Psychiatry 19:59-67. 2011..A research framework for future evaluation of the use of antipsychotic therapy in the critically ill is proposed... - Current perceptions and practices surrounding the recognition and treatment of delirium in the intensive care unit: a survey of 250 critical care pharmacists from eight StatesJohn W Devlin
School of Pharmacy, Northeastern University, Boston, MA, USA
Ann Pharmacother 45:1217-29. 2011..Pharmacists are key members of the intensive care unit (ICU) team; however, few data exist regarding their clinical role, perceptions, and current practices in recognizing and managing delirium... - An in vitro comparison of different providers to deliver four proton pump inhibitor products through a feeding tubeJ W Devlin
School of Pharmacy, Northeastern University, Boston, MA 02115, USA
Aliment Pharmacol Ther 24:1603-11. 2006..It is unclear how delivery through a feeding tube compares between esomeprazole in water, lansoprazole oral disintegrating tablet in water, omeprazole/NaHCO(3) in water and simplified lansoprazole suspension... - Albumin for fluid resuscitation: implications of the Saline versus Albumin Fluid EvaluationJohn W Devlin
School of Pharmacy, Northeastern University, Mugar Building, Boston, MA 02115, USA
Am J Health Syst Pharm 62:637-42. 2005 - Treatment options and formulary considerations in the management of acid suppression in critically ill patients. IntroductionJohn W Devlin
Northeastern University School of Pharmacy, and Medical Intensive Care Unit, Tufts-New England Medical Center, Mugar #206, 360 Huntington Avenue, Boston, MA 02115, USA
Am J Health Syst Pharm 62:S2-3. 2005 - Proton pump inhibitor formulary considerations in the acutely ill. Part 1: Pharmacology, pharmacodynamics, and available formulationsJohn W Devlin
School of Pharmacy, Northeastern University, Boston, MA 02115 5000, USA
Ann Pharmacother 39:1667-77. 2005.... - Proton pump inhibitors for acid suppression in the intensive care unit: formulary considerationsJohn W Devlin
Northeastern University School of Pharmacy, and Medical Intensive Care Unit, Tufts New England Medical Center, Mugar 206, 360 Huntington Avenue, Boston, MA 02115, USA
Am J Health Syst Pharm 62:S24-30. 2005.... - Fenoldopam versus nitroprusside for the treatment of hypertensive emergencyJohn W Devlin
School of Pharmacy, Northeastern University, Boston, MA 02115 5001, USA
Ann Pharmacother 38:755-9. 2004..While sodium nitroprusside remains first-line therapy for hypertensive emergency (HEM), fenoldopam is increasingly being used because of its benign safety profile and potential renal protective effects... - Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factorsJohn W Devlin
School of Pharmacy, Northeastern University, and the Department of Pharmacy, Tufts New England Medical Center, Boston, Massachusetts 02115, USA
Pharmacotherapy 25:1348-52. 2005..To characterize the frequency, severity, risk factors, and clinician response to propofol-associated hypertriglyceridemia and hypertriglyceridemia-associated pancreatitis... - Proton pump inhibitor formulary considerations in the acutely ill. Part 2: Clinical efficacy, safety, and economicsJohn W Devlin
School of Pharmacy, Northeastern University Medical Intensive Care Unit, Tufts New England Medical Center, Boston, MA 02115 5000, USA
Ann Pharmacother 39:1844-51. 2005.... - A tool for measuring active learning in the classroomJenny A Van Amburgh
Bouve College of Health Sciences, Northeastern University, Boston, MA 02115, USA
Am J Pharm Educ 71:85. 2007..To develop a valid and reliable active-learning inventory tool for use in large classrooms and compare faculty perceptions of active-learning using the Active-Learning Inventory Tool... - Atypical antipsychotics versus haloperidol for treatment of delirium in acutely ill patientsRhonda S Rea
School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Pharmacotherapy 27:588-94. 2007..However, these conclusions are based on a limited number of studies; larger comparative trials are needed to elucidate the role of atypical antipsychotics for treating delirium in this population... - Propofol associated with a shorter duration of mechanical ventilation than scheduled intermittent lorazepam: a database analysis using Project IMPACTJeffrey J Fong
School of Pharmacy, Northeastern University, Boston, MA 02115, USA
Ann Pharmacother 41:1986-91. 2007.... - Assessment of delirium in the intensive care unit: nursing practices and perceptionsJohn W Devlin
Northeastern University School of Pharmacy, Boston, Massachusetts, USA
Am J Crit Care 17:555-65; quiz 566. 2008..Despite practice guidelines promoting delirium assessment in intensive care, few data exist regarding current delirium assessment practices among nurses and how these practices compare with those for sedation assessment... - Predictors of mortality in patients with suspected propofol infusion syndromeJeffrey J Fong
Northeastern University School of Pharmacy, Boston, MA, USA
Crit Care Med 36:2281-7. 2008..To identify predictors of mortality in patients with suspected propofol infusion syndrome and to develop a simple scoring system to identify patients with suspected propofol infusion syndrome who are most at risk of death... - Critical care pharmacy services in United States hospitalsRobert MacLaren
Department of Clinical Pharmacy, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Ann Pharmacother 40:612-8. 2006..Critical care pharmacy activities have been described as fundamental, desirable, and optimal, but actual services provided have not been evaluated... - Impact of an institution-specific hospital-acquired pneumonia protocol on the appropriateness of antibiotic therapy and patient outcomesJason W Lancaster
Northeastern University School of Pharmacy, Boston, Massachusetts 02115, USA
Pharmacotherapy 28:852-62. 2008..To evaluate the impact of a hospital-acquired pneumonia (HAP) protocol on appropriateness of empiric antibiotic therapy, antibiotic deescalation, antibiotic duration, patient mortality, and length of stay... - Corticosteroids for prevention of postextubation laryngeal edema in adultsRussel J Roberts
School of Pharmacy, Northeastern University, Boston, MA 02111, USA
Ann Pharmacother 42:686-91. 2008..To evaluate the efficacy and safety of prophylactic corticosteroid therapy in preventing postextubation laryngeal edema (PELE) and the need for reintubation in adults... - Factors influencing variability in compliance rates and clinical outcomes among three different severe sepsis bundlesJeffrey J Fong
School of Pharmacy, Northeastern University, Boston, MA 02115, USA
Ann Pharmacother 41:929-36. 2007.... - Identifying factors that could account for differences in duration of mechanical ventilation between intermittent lorazepam- and propofol-treated patientsJohn W Devlin
Crit Care Med 34:3063-4; author reply 3064. 2006 - The cost-effectiveness of proton pump inhibitors for bleeding peptic ulcers: The unanswered questionsJohn W Devlin
Crit Care Med 32:1415-6. 2004 - Bioavailability of gatifloxacin by gastric tube administration with and without concomitant enteral feeding in critically ill patientsSalmaan Kanji
College of Pharmacy, Wayne State University, Detroit, MI, USA
Crit Care Med 31:1347-52. 2003..More research is needed to identify those patients in whom gatifloxacin bioavailability is reduced and for whom an empirical increase in gatifloxacin dose should be considered... - Greater immediate gastric acid suppression with lansoprazole 30 mg administered as a 2-minute intravenous bolus injection versus a 30-minute infusionDavid C Metz
Division of Gastroenterology, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Pharmacotherapy 28:301-7. 2008..To compare the pharmacokinetics, pharmacodynamics, and safety of lansoprazole administered as a 2-minute intravenous bolus injection versus a 30-minute continuous infusion... - Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patientsJeffrey F Barletta
JAMA 299:1541-2; author reply 1542. 2008 - Reversing oversedation in the intensive care unit: the role of pharmacists in energizing guideline efforts and overcoming protocol fatigueJohn W Devlin
Crit Care Med 36:626-8. 2008 - Effect of low-calorie parenteral nutrition on the incidence and severity of hyperglycemia in surgical patients: a randomized, controlled trialChristine L Ahrens
Department of Pharmacy, The Cleveland Clinic Foundation, Cleveland, OH, USA
Crit Care Med 33:2507-12. 2005..PN regimens should not exceed a dextrose administration rate of 4 mg/kg/min to avoid hyperglycemic events... - Intensive care unit sedation: waking up clinicians to the gap between research and practiceJohn W Devlin
Crit Care Med 34:556-7. 2006 - An evaluation of the cost effectiveness of drotrecogin alfa (activated) relative to the number of organ system failuresMadeline Betancourt
College of Pharmacy, Wayne State University, Detroit, Michigan, USA
Pharmacoeconomics 21:1331-40. 2003.... - Clinical practice guidelines for the maintenance of patient physical safety in the intensive care unit: use of restraining therapies--American College of Critical Care Medicine Task Force 2001-2002Gerald A Maccioli
Critical Health Systems, Raleigh Practice Center, NC, USA
Crit Care Med 31:2665-76. 2003..CONCLUSIONS: The task force developed nine recommendations with regard to the use of physical restraints and pharmacologic therapies to maintain patient safety in the intensive care unit... - Adverse drug event reporting in intensive care units: a survey of current practicesSandra L Kane-Gill
University of Pittsburgh, Center for Pharmacoinformatics and Outcomes Research, PA 15261, USA
Ann Pharmacother 40:1267-73. 2006..Understanding the frequency with which institutions incorporate standardized operational ADE/ADR definitions, triggers, and evaluation tools in this population will facilitate benchmarking between hospitals... - Should sedation be standardized in the intensive care unit?Marjolein de Wit
Crit Care Med 36:1649-51. 2008