Richard Deth

Summary

Affiliation: Northeastern University
Country: USA

Publications

  1. pmc Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism
    Christina R Muratore
    Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA, USA
    PLoS ONE 8:e56927. 2013
  2. pmc A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States
    Renee Dufault
    Food Ingredient and Health Research Institute, Ocean View, HI, USA
    Clin Epigenetics 4:6. 2012
  3. ncbi request reprint How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
    Richard Deth
    Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02468, United States
    Neurotoxicology 29:190-201. 2008
  4. pmc Morphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake
    Malav Trivedi
    Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts M T, J S, N H, R D Center for Molecular Biology and Biotechnology, Florida Atlantic University, Jupiter, Florida R D and Department of Environmental Epidemiology, Harvard School of Public Health, Boston, Massachusetts H M B
    Mol Pharmacol 85:747-57. 2014
  5. ncbi request reprint Soluble oligomers of amyloid-β cause changes in redox state, DNA methylation, and gene transcription by inhibiting EAAT3 mediated cysteine uptake
    Nathaniel Hodgson
    Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA
    J Alzheimers Dis 36:197-209. 2013

Collaborators

  • Hyang Min Byun
  • Malav Trivedi
  • Nathaniel Hodgson
  • Christina R Muratore
  • Renee Dufault
  • Jayni Shah
  • Carla Lintas
  • Nathaniel W Hodgson
  • Christina Muratore
  • Hamid M Abdolmaleky
  • Shaomin Li
  • Suzanne de la Monte
  • Malav S Trivedi
  • Antonio M Persico
  • Roseanne Schnoll
  • Walter J Lukiw
  • David Wallinga
  • Raquel Crider

Detail Information

Publications6

  1. pmc Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism
    Christina R Muratore
    Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA, USA
    PLoS ONE 8:e56927. 2013
    ..Factors adversely affecting MS activity, such as oxidative stress, can be a source of risk for neurological disorders across the lifespan via their impact on methylation reactions, including epigenetic regulation of gene expression...
  2. pmc A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States
    Renee Dufault
    Food Ingredient and Health Research Institute, Ocean View, HI, USA
    Clin Epigenetics 4:6. 2012
    ....
  3. ncbi request reprint How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
    Richard Deth
    Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02468, United States
    Neurotoxicology 29:190-201. 2008
    ....
  4. pmc Morphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake
    Malav Trivedi
    Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts M T, J S, N H, R D Center for Molecular Biology and Biotechnology, Florida Atlantic University, Jupiter, Florida R D and Department of Environmental Epidemiology, Harvard School of Public Health, Boston, Massachusetts H M B
    Mol Pharmacol 85:747-57. 2014
    ..Since epigenetic changes are implicated in drug addiction and tolerance phenomenon, this study could potentially extrapolate to elucidate a novel mechanism of action for other drugs of abuse. ..
  5. ncbi request reprint Soluble oligomers of amyloid-β cause changes in redox state, DNA methylation, and gene transcription by inhibiting EAAT3 mediated cysteine uptake
    Nathaniel Hodgson
    Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA
    J Alzheimers Dis 36:197-209. 2013
    ..We describe a role of IGF-1 signaling in regulating redox and methylation homeostasis, and propose this to be a pathogenic target of oAβ...