Research Topics
| Glenn M WalkerSummaryAffiliation: North Carolina State University Country: USA Publications
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Detail Information
Publications
A linear dilution microfluidic device for cytotoxicity assaysGlenn M Walker
Joint Department of Biomedical Engineering at The University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27695 7115, USA
Lab Chip 7:226-32. 2007....
A serial dilution microfluidic device for cytotoxicity assaysAdrian T O'Neill
Dept of Biomed Eng, North Carolina Univ, Chapel Hill, NC, USA
Conf Proc IEEE Eng Med Biol Soc 1:2836-9. 2006..9993. The device functions equivalently over a wide range of flow rates. The standard deviation of dilution values averages 0.76% over six flow rates spanning 0.5 to 16 microl min(-1)...
Microfluidic cytometer for the characterization of cell lysisJeffrey R Soohoo
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, USA
Anal Chem 84:2195-201. 2012..Lysis began after 0.2 s and could be initiated with a lysis reagent concentration of 1.0% (68.5 mM). An equation that related lysis reagent concentration, [A], to erythrocyte lysis, [B], was determined to be [B] = -0.77[A](0.29)t...
Microfabricated curtains for controlled cell seeding in high throughput microfluidic systemsAdrian T O'Neill
Joint Department of Biomedical Engineering at The University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27695 7115, USA
Lab Chip 9:1756-62. 2009..Curtain use permitted high initial cell seeding densities and increased the amount of time cells can be cultured compared to multi-well plates...
Microfluidic aqueous two phase system for leukocyte concentration from whole bloodJeffrey R Soohoo
The Joint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina at Chapel Hill, Raleigh, NC 27695 7115, USA
Biomed Microdevices 11:323-9. 2009..The most effective configuration was the Dex-PEG-Dex stream pattern which on average increased the ratio of leukocytes to erythrocytes by a factor of 9.13 over unconcentrated blood...
Physics and applications of microfluidics in biologyDavid J Beebe
Department of Biomedical Engineering, University of Wisconsin, Madison 53706, USA
Annu Rev Biomed Eng 4:261-86. 2002..The focus of this review is microscale phenomena and the use of the physics of the scale to create devices and systems that provide functionality useful to the life sciences...
Microenvironment design considerations for cellular scale studiesGlenn M Walker
Department of Molecular Physiology and Biophysics, Vanderbuilt Institute for Integrative Biosystem Research and Education, Vanderbuilt University, Nashville, TN 37232, USA
Lab Chip 4:91-7. 2004..Current research using microtechnology to investigate in vitro cellular microenvironments is presented and areas where more research is needed in characterizing the in vitro microenvironment are outlined...
Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic isletsJonathan V Rocheleau
Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232-0615, USA
Proc Natl Acad Sci U S A 101:12899-903. 2004....
Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generatorGlenn M Walker
Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, Nashville, TN 37235, USA
Lab Chip 5:611-8. 2005....
