Research Topics
| Donald E ThrallSummaryAffiliation: North Carolina State University Country: USA Publications
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Detail Information
Publications
Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribedD E Thrall
College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Int J Hyperthermia 16:415-28. 2000....- Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain massesD E Thrall
College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Int J Hyperthermia 15:383-98. 1999..Results suggest that use of WBH alone to increase the temperature of intracranial tumours as a means to improve radiation therapy outcome is not a successful strategy... - Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomasD E Thrall
College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Int J Hyperthermia 22:365-73. 2006..In other tumours, potentially less advantageous changes in oxygenation may be hyperthermia fractionation related and this deserves further investigation... 
Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapyDonald E Thrall
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
Clin Cancer Res 11:5206-14. 2005..To test that prospective delivery of higher thermal dose is associated with longer tumor control duration...- Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumorsMarlene L Hauck
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
Clin Cancer Res 12:4004-10. 2006.... - A retrospective analysis of 140 dogs with oral melanoma treated with external beam radiationDavid R Proulx
College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
Vet Radiol Ultrasound 44:352-9. 2003..The high metastatic rate observed with this disease and the inefficacy of systemic chemotherapy indicate that further investigation into novel therapies is warranted... - A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasationMiriam M Kleiter
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
Clin Cancer Res 12:6800-7. 2006..CONCLUSIONS: The use of a radiolabeled tracer has potential value to monitor drug delivery and estimate the effect of an intervention aimed to increase liposomal accumulation, such as local hyperthermia... - Chemotherapy followed by abdominal cavity irradiation for feline lymphoblastic lymphomaLaurel E Williams
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 51:681-7. 2010..Results of this study suggest that 15 Gy total abdomen fractionated radiation therapy after induction chemotherapy is tolerated satisfactorily. This protocol is suitable for further testing to quantify efficacy... - Chemotherapy followed by half-body radiation therapy for canine lymphomaLaurel E Williams
Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
J Vet Intern Med 18:703-9. 2004.... - A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomasFarzan Siddiqui
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Mol Cancer Ther 6:380-9. 2007..The maximum tolerated dose of the feline IL-12 adenoviral vector was 10(10) pfu/tumor as dose-limiting toxicities were noted at the 4 x 10(10) pfu dose... - Usefulness of a half-fourier acquisition single-shot turbo spin-echo pulse sequence in identifying arachnoid diverticula in dogsGabriela S Seiler
Department of Molecular Biomedical Sciences, North Carolina State University, 1052 William Moore Drive, Raleigh, NC 27607, USA
Vet Radiol Ultrasound 53:157-61. 2012.... - Malignant tumor formation in dogs previously irradiated for acanthomatous epulisMargaret C McEntee
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Radiol Ultrasound 45:357-61. 2004..The only statistically significant variable in the survival analysis was age, with dogs less than 8.3 years old having a significantly longer median overall survival (2322 days) than dogs older than 8.3 years (1106 days; P<0.0001)... - Preoperative radiotherapy for vaccine associated sarcoma in 92 catsTetsuya Kobayashi
College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Vet Radiol Ultrasound 43:473-9. 2002..Preoperative irradiation is an effective treatment for cats with vaccine associated sarcoma, especially if complete excision can be accomplished following irradiation... - Characterization of normal tissue complications in 51 dogs undergoing definitive pelvic region irradiationJennifer J Arthur
Department of Molecular Biomedical Sciences, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough St, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 49:85-9. 2008..Based on the observed complication rate, consideration can be given to reducing dose per fraction in dogs receiving definitive pelvic region irradiation to <3 Gy... - Images from the 2002 ACVR certification examination: small animal diagnosis electiveDonald E Thrall
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 44:118-21. 2003 
Thermal dose fractionation affects tumour physiological responseDonald E Thrall
College of Veterinary Medicine, North Carolina State University, Raleigh, USA
Int J Hyperthermia 28:431-40. 2012..To evaluate this we assessed the effect of administering the same total thermal dose, approximately 30 CEM43T(90), in one versus three to four fractions per week, over 5 weeks...- MRI features of metacarpo(tarso)phalangeal region lameness in 40 horsesLiara M Gonzalez
College of Veterinary Medicine, North Carolina State University, Hillsborough Street 4700, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 51:404-14. 2010..MRI provided information that was complementary to radiography, ultrasonography, and nuclear scintigraphy and that allowed for a comprehensive evaluation of all structures in the MP joint region and a diagnosis in all 40 horses... - Use of photon fields with noncoincident isocenters to improve homogeneity of dose distributionAmy F Pruitt
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 45:471-5. 2004..Improved tumor dose distribution was achieved with the addition of a smaller field having a different isocenter... - Expression of cyclooxygenase-2 in canine epithelial nasal tumorsMiriami Kleiter
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 45:255-60. 2004..A combination therapy of irradiation and a selective COX-2 inhibitor appears worthy of clinical investigation in the treatment of canine epithelial nasal tumors... - Magnetic resonance imaging features of lissencephaly in 2 Lhasa ApsosMiyoko Saito
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, USA
Vet Radiol Ultrasound 43:331-7. 2002..MR is the imaging modality of choice for antemortem diagnosis of canine lissencephaly... - A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia markerMiriam M Kleiter
College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27514-7512, USA
Int J Radiat Oncol Biol Phys 64:592-602. 2006..Selective cellular uptake and concomitant higher levels of binding in regions of hypoxia at the high end of pH gradients might account for the greater extent of pimonidazole binding... - Results of radiation therapy in 19 dogs with cutaneous mast cell tumor and regional lymph node metastasisKelly Chaffin
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Vet Radiol Ultrasound 43:392-5. 2002..The disease-free survival in dogs with stage 2 mast cell tumor suggests that the combination of surgery, irradiation, and prednisone for the primary tumor along with irradiation of the positive lymph node is effective... - Comparison of isodose distributions in canine brain in heterogeneity-corrected versus uncorrected treatment plans using 6 MV photonsJ Lyons
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 48:292-6. 2007.... - Two anatomic resources of canine pelvic limb muscles based on CT and MRISarena K Sunico
College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
Vet Radiol Ultrasound 53:266-72. 2012..Both projects are hosted on an open-access website, http://3dvetanatomy.ncsu.edu/.. - Radiation therapy communication: nasal passage and paranasal sinus lymphoma in a ponyMathew Gerard
Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 51:97-101. 2010..These results suggest that localized equine B-cell lymphoma is radiosensitive, and that palliative radiation therapy is a reasonable consideration for large tumors, even when tumor volume prevents all gross tumor from being irradiated... - Imaging diagnosis-magnetic resonance imaging pulsatility artifact in the canine cervical spineGabriela S Seiler
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 52:313-6. 2011.... - Imaging diagnosis--synchronous primary brain tumors in a dogEdward MacKillop
Department of Clinical Sciences North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA
Vet Radiol Ultrasound 48:550-3. 2007 - CT findings of intracranial blastomycosis in a dogMiyoko Saito
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Vet Radiol Ultrasound 43:16-21. 2002..This is particularly true in dogs with systemic or ocular blastomycosis, which appear to be at higher risk of developing CNS involvement... - Evaluation of two objective methods to optimize kVp and personnel exposure using a digital indirect flat panel detector and simulated veterinary patientsChristina Copple
Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA
Vet Radiol Ultrasound 54:9-16. 2013..Very large patients require a higher kVp than 100 regardless of the optimization method used. Personnel exposure from optimized techniques was low and not expected to exceed annual occupational dose limits... - Imaging dogs with suspected disc herniation: pros and cons of myelography, computed tomography, and magnetic resonanceIan Robertson
Department of Molecular Biomedical Sciences College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 52:S81-4. 2011..Myelography is still considered adequate for diagnosis of disc herniation when MR and CT are unavailable... - Radiographic features of aortic bulb/valve mineralization in 20 dogsJames P Douglass
Department of Anatomy, North Carolina State University, College of Veterinary Medicine, Raleigh 27606, USA
Vet Radiol Ultrasound 44:20-7. 2003..No clinical signs attributable to the mineralization were observed... - Retrospective analysis of axial skeleton osteosarcoma in 22 large-breed dogsM E Dickerson
Department of Companion Animal, College of Veterinary Medicine, North Carolina State University, Raleigh, USA
J Vet Intern Med 15:120-4. 2001..Definitive radiation therapy may have a role in the treatment of axial skeleton osteosarcoma... - Immunohistochemical detection of a hypoxia marker in spontaneous canine tumoursJ M Cline
College of Veterinary Medicine, North Carolina State University, Raleigh 27606
Br J Cancer 62:925-31. 1990..Generally, binding to normal tissues was not observed. However, binding to smooth muscle cells surrounding arterioles in some sections of normal tissue and tumour tissue was observed... - Clinical, magnetic resonance, and sonographic imaging findings in horses with proximal plantar metatarsal painRaphael Labens
College of Veterinary Medicine, North Carolina State University, Hillsborough Street 4700, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 51:11-8. 2010.... - Diagnostic accuracy of magnetic resonance imaging for meniscal tears in dogs affected with naturally occuring cranial cruciate ligament ruptureLaurent Blond
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
Vet Radiol Ultrasound 49:425-31. 2008..High-field MR imaging is a reliable method to diagnose meniscal tears preoperatively and this may be useful in selecting the surgical approach to clinically abnormal joints and may decrease the need for arthrotomy... - Images from the 2001 ACVR certifying examination: CT/MR elective sectionDonald E Thrall
College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Vet Radiol Ultrasound 43:68-9. 2002 - Effect of wetness level on the suitability of wet gauze as a substitute for Superflab as a bolus material for use with 6 mv photonsJerome Benoit
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Vet Radiol Ultrasound 50:555-9. 2009..02 g/cm3 can be used as a substitute. Judging the water content of wet gauze subjectively is not acceptable as over- or under wetness can lead to decreased effectiveness of the bolus material... - Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumoursK Shiomitsu
Department of Molecular Biomedical Science, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
Vet Comp Oncol 7:106-14. 2009.... - Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapyMichael Lora-Michiels
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
Clin Cancer Res 12:5733-40. 2006..The objective was to test whether tumor pH and (31)P magnetic resonance spectroscopic end points were related to treatment outcome in pet canine patients with spontaneous soft tissue sarcomas treated with thermoradiotherapy... - Images from the 2003 ACVR oral certification examination: thorax sectionDonald E Thrall
Vet Radiol Ultrasound 45:180-2. 2004 - Use of radiography in combination with computed tomography for the assessment of noncardiac thoracic disease in the dog and catAndrew B Prather
Veterinary Specialists Center, 9905 S. Highway 17-92, Maitland, FL, USA
Vet Radiol Ultrasound 46:114-21. 2005..In conclusion, CT is a valuable tool for evaluating intrathoracic disease. CT provides additional cross-sectional anatomic information that can aid in anatomic localization and evaluation of the extent of the pathology in question... - Magnetic resonance imaging findings in a dog with caudal aortic thromboembolism and ischemic myopathyPeter J Brofman
Veterinary Specialty Hospital of the Carolinas, 6405 Tryon Rd, Cary, NC 27511, USA
Vet Radiol Ultrasound 47:334-8. 2006