Donald E Thrall

Summary

Affiliation: North Carolina State University
Country: USA

Publications

  1. ncbi request reprint Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribed
    D E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Int J Hyperthermia 16:415-28. 2000
  2. ncbi request reprint Chemotherapy followed by abdominal cavity irradiation for feline lymphoblastic lymphoma
    Laurel E Williams
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 51:681-7. 2010
  3. ncbi request reprint Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas
    D E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Int J Hyperthermia 22:365-73. 2006
  4. ncbi request reprint Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses
    D E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Int J Hyperthermia 15:383-98. 1999
  5. pmc Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy
    Donald E Thrall
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Clin Cancer Res 11:5206-14. 2005
  6. ncbi request reprint Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors
    Marlene L Hauck
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Clin Cancer Res 12:4004-10. 2006
  7. ncbi request reprint A retrospective analysis of 140 dogs with oral melanoma treated with external beam radiation
    David R Proulx
    College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
    Vet Radiol Ultrasound 44:352-9. 2003
  8. ncbi request reprint A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasation
    Miriam M Kleiter
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Clin Cancer Res 12:6800-7. 2006
  9. ncbi request reprint Chemotherapy followed by half-body radiation therapy for canine lymphoma
    Laurel E Williams
    Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    J Vet Intern Med 18:703-9. 2004
  10. ncbi request reprint A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas
    Farzan Siddiqui
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Mol Cancer Ther 6:380-9. 2007

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribed
    D E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Int J Hyperthermia 16:415-28. 2000
    ....
  2. ncbi request reprint Chemotherapy followed by abdominal cavity irradiation for feline lymphoblastic lymphoma
    Laurel E Williams
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 51:681-7. 2010
    ..Results of this study suggest that 15 Gy total abdomen fractionated radiation therapy after induction chemotherapy is tolerated satisfactorily. This protocol is suitable for further testing to quantify efficacy...
  3. ncbi request reprint Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas
    D E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Int J Hyperthermia 22:365-73. 2006
    ..In other tumours, potentially less advantageous changes in oxygenation may be hyperthermia fractionation related and this deserves further investigation...
  4. ncbi request reprint Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses
    D E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Int J Hyperthermia 15:383-98. 1999
    ..Results suggest that use of WBH alone to increase the temperature of intracranial tumours as a means to improve radiation therapy outcome is not a successful strategy...
  5. pmc Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy
    Donald E Thrall
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Clin Cancer Res 11:5206-14. 2005
    ..To test that prospective delivery of higher thermal dose is associated with longer tumor control duration...
  6. ncbi request reprint Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors
    Marlene L Hauck
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Clin Cancer Res 12:4004-10. 2006
    ....
  7. ncbi request reprint A retrospective analysis of 140 dogs with oral melanoma treated with external beam radiation
    David R Proulx
    College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
    Vet Radiol Ultrasound 44:352-9. 2003
    ..The high metastatic rate observed with this disease and the inefficacy of systemic chemotherapy indicate that further investigation into novel therapies is warranted...
  8. ncbi request reprint A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasation
    Miriam M Kleiter
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Clin Cancer Res 12:6800-7. 2006
    ..The purpose of this study was to determine if a small tracer dose of technetium-99m (99mTc)-labeled liposomes could be used to quantify the effect of local hyperthermia on intratumoral Doxil extravasation...
  9. ncbi request reprint Chemotherapy followed by half-body radiation therapy for canine lymphoma
    Laurel E Williams
    Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    J Vet Intern Med 18:703-9. 2004
    ....
  10. ncbi request reprint A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas
    Farzan Siddiqui
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Mol Cancer Ther 6:380-9. 2007
    ..The maximum tolerated dose of the feline IL-12 adenoviral vector was 10(10) pfu/tumor as dose-limiting toxicities were noted at the 4 x 10(10) pfu dose...
  11. ncbi request reprint Usefulness of a half-fourier acquisition single-shot turbo spin-echo pulse sequence in identifying arachnoid diverticula in dogs
    Gabriela S Seiler
    Department of Molecular Biomedical Sciences, North Carolina State University, 1052 William Moore Drive, Raleigh, NC 27607, USA
    Vet Radiol Ultrasound 53:157-61. 2012
    ....
  12. ncbi request reprint Malignant tumor formation in dogs previously irradiated for acanthomatous epulis
    Margaret C McEntee
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Vet Radiol Ultrasound 45:357-61. 2004
    ..The only statistically significant variable in the survival analysis was age, with dogs less than 8.3 years old having a significantly longer median overall survival (2322 days) than dogs older than 8.3 years (1106 days; P<0.0001)...
  13. ncbi request reprint Images from the 2002 ACVR certification examination: small animal diagnosis elective
    Donald E Thrall
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 44:118-21. 2003
  14. ncbi request reprint Characterization of normal tissue complications in 51 dogs undergoing definitive pelvic region irradiation
    Jennifer J Arthur
    Department of Molecular Biomedical Sciences, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough St, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 49:85-9. 2008
    ..Based on the observed complication rate, consideration can be given to reducing dose per fraction in dogs receiving definitive pelvic region irradiation to <3 Gy...
  15. ncbi request reprint Preoperative radiotherapy for vaccine associated sarcoma in 92 cats
    Tetsuya Kobayashi
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Vet Radiol Ultrasound 43:473-9. 2002
    ..Preoperative irradiation is an effective treatment for cats with vaccine associated sarcoma, especially if complete excision can be accomplished following irradiation...
  16. doi request reprint Radiographic characterization of presumed plate-like atelectasis in 75 nonanesthetized dogs and 15 cats
    Robson F Giglio
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    Vet Radiol Ultrasound 54:326-31. 2013
    ....
  17. pmc Thermal dose fractionation affects tumour physiological response
    Donald E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh, USA
    Int J Hyperthermia 28:431-40. 2012
    ..To evaluate this we assessed the effect of administering the same total thermal dose, approximately 30 CEM43T(90), in one versus three to four fractions per week, over 5 weeks...
  18. ncbi request reprint Expression of cyclooxygenase-2 in canine epithelial nasal tumors
    Miriami Kleiter
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 45:255-60. 2004
    ..A combination therapy of irradiation and a selective COX-2 inhibitor appears worthy of clinical investigation in the treatment of canine epithelial nasal tumors...
  19. ncbi request reprint Use of photon fields with noncoincident isocenters to improve homogeneity of dose distribution
    Amy F Pruitt
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 45:471-5. 2004
    ..Improved tumor dose distribution was achieved with the addition of a smaller field having a different isocenter...
  20. ncbi request reprint MRI features of metacarpo(tarso)phalangeal region lameness in 40 horses
    Liara M Gonzalez
    College of Veterinary Medicine, North Carolina State University, Hillsborough Street 4700, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 51:404-14. 2010
    ..MRI provided information that was complementary to radiography, ultrasonography, and nuclear scintigraphy and that allowed for a comprehensive evaluation of all structures in the MP joint region and a diagnosis in all 40 horses...
  21. ncbi request reprint Magnetic resonance imaging features of lissencephaly in 2 Lhasa Apsos
    Miyoko Saito
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, USA
    Vet Radiol Ultrasound 43:331-7. 2002
    ..MR is the imaging modality of choice for antemortem diagnosis of canine lissencephaly...
  22. ncbi request reprint Results of radiation therapy in 19 dogs with cutaneous mast cell tumor and regional lymph node metastasis
    Kelly Chaffin
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Vet Radiol Ultrasound 43:392-5. 2002
    ..The disease-free survival in dogs with stage 2 mast cell tumor suggests that the combination of surgery, irradiation, and prednisone for the primary tumor along with irradiation of the positive lymph node is effective...
  23. ncbi request reprint A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker
    Miriam M Kleiter
    College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27514 7512, USA
    Int J Radiat Oncol Biol Phys 64:592-602. 2006
    ..Pimonidazole HCl is widely used in immunohistochemical analyses of hypoxia in normal and malignant tissues. The present study investigates oral administration as a means of minimizing invasiveness...
  24. ncbi request reprint Comparison of isodose distributions in canine brain in heterogeneity-corrected versus uncorrected treatment plans using 6 MV photons
    J Lyons
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 48:292-6. 2007
    ....
  25. doi request reprint Two anatomic resources of canine pelvic limb muscles based on CT and MRI
    Sarena K Sunico
    College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
    Vet Radiol Ultrasound 53:266-72. 2012
    ..Both projects are hosted on an open-access website, http://3dvetanatomy.ncsu.edu/..
  26. ncbi request reprint Radiation therapy communication: nasal passage and paranasal sinus lymphoma in a pony
    Mathew Gerard
    Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 51:97-101. 2010
    ..These results suggest that localized equine B-cell lymphoma is radiosensitive, and that palliative radiation therapy is a reasonable consideration for large tumors, even when tumor volume prevents all gross tumor from being irradiated...
  27. doi request reprint Imaging diagnosis-magnetic resonance imaging pulsatility artifact in the canine cervical spine
    Gabriela S Seiler
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 52:313-6. 2011
    ....
  28. ncbi request reprint Imaging diagnosis--synchronous primary brain tumors in a dog
    Edward MacKillop
    Department of Clinical Sciences North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA
    Vet Radiol Ultrasound 48:550-3. 2007
  29. ncbi request reprint CT findings of intracranial blastomycosis in a dog
    Miyoko Saito
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Vet Radiol Ultrasound 43:16-21. 2002
    ..This is particularly true in dogs with systemic or ocular blastomycosis, which appear to be at higher risk of developing CNS involvement...
  30. doi request reprint Evaluation of two objective methods to optimize kVp and personnel exposure using a digital indirect flat panel detector and simulated veterinary patients
    Christina Copple
    Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA
    Vet Radiol Ultrasound 54:9-16. 2013
    ..Very large patients require a higher kVp than 100 regardless of the optimization method used. Personnel exposure from optimized techniques was low and not expected to exceed annual occupational dose limits...
  31. ncbi request reprint Radiographic features of aortic bulb/valve mineralization in 20 dogs
    James P Douglass
    Department of Anatomy, North Carolina State University, College of Veterinary Medicine, Raleigh 27606, USA
    Vet Radiol Ultrasound 44:20-7. 2003
    ..No clinical signs attributable to the mineralization were observed...
  32. doi request reprint Imaging dogs with suspected disc herniation: pros and cons of myelography, computed tomography, and magnetic resonance
    Ian Robertson
    Department of Molecular Biomedical Sciences College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 52:S81-4. 2011
    ..Myelography is still considered adequate for diagnosis of disc herniation when MR and CT are unavailable...
  33. pmc Immunohistochemical detection of a hypoxia marker in spontaneous canine tumours
    J M Cline
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606
    Br J Cancer 62:925-31. 1990
    ..Generally, binding to normal tissues was not observed. However, binding to smooth muscle cells surrounding arterioles in some sections of normal tissue and tumour tissue was observed...
  34. ncbi request reprint Retrospective analysis of axial skeleton osteosarcoma in 22 large-breed dogs
    M E Dickerson
    Department of Companion Animal, College of Veterinary Medicine, North Carolina State University, Raleigh, USA
    J Vet Intern Med 15:120-4. 2001
    ..Definitive radiation therapy may have a role in the treatment of axial skeleton osteosarcoma...
  35. ncbi request reprint Clinical, magnetic resonance, and sonographic imaging findings in horses with proximal plantar metatarsal pain
    Raphael Labens
    College of Veterinary Medicine, North Carolina State University, Hillsborough Street 4700, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 51:11-8. 2010
    ....
  36. ncbi request reprint Effect of wetness level on the suitability of wet gauze as a substitute for Superflab as a bolus material for use with 6 mv photons
    Jerome Benoit
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Radiol Ultrasound 50:555-9. 2009
    ..02 g/cm3 can be used as a substitute. Judging the water content of wet gauze subjectively is not acceptable as over- or under wetness can lead to decreased effectiveness of the bolus material...
  37. ncbi request reprint Diagnostic accuracy of magnetic resonance imaging for meniscal tears in dogs affected with naturally occuring cranial cruciate ligament rupture
    Laurent Blond
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
    Vet Radiol Ultrasound 49:425-31. 2008
    ..High-field MR imaging is a reliable method to diagnose meniscal tears preoperatively and this may be useful in selecting the surgical approach to clinically abnormal joints and may decrease the need for arthrotomy...
  38. ncbi request reprint Images from the 2001 ACVR certifying examination: CT/MR elective section
    Donald E Thrall
    College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    Vet Radiol Ultrasound 43:68-9. 2002
  39. doi request reprint Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumours
    K Shiomitsu
    Department of Molecular Biomedical Science, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
    Vet Comp Oncol 7:106-14. 2009
    ....
  40. ncbi request reprint Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy
    Michael Lora-Michiels
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Cancer Res 12:5733-40. 2006
    ..The objective was to test whether tumor pH and (31)P magnetic resonance spectroscopic end points were related to treatment outcome in pet canine patients with spontaneous soft tissue sarcomas treated with thermoradiotherapy...
  41. ncbi request reprint Images from the 2003 ACVR oral certification examination: thorax section
    Donald E Thrall
    Vet Radiol Ultrasound 45:180-2. 2004
  42. ncbi request reprint Use of radiography in combination with computed tomography for the assessment of noncardiac thoracic disease in the dog and cat
    Andrew B Prather
    Veterinary Specialists Center, 9905 S Highway 17 92, Maitland, FL, USA
    Vet Radiol Ultrasound 46:114-21. 2005
    ..In conclusion, CT is a valuable tool for evaluating intrathoracic disease. CT provides additional cross-sectional anatomic information that can aid in anatomic localization and evaluation of the extent of the pathology in question...
  43. ncbi request reprint Magnetic resonance imaging findings in a dog with caudal aortic thromboembolism and ischemic myopathy
    Peter J Brofman
    Veterinary Specialty Hospital of the Carolinas, 6405 Tryon Rd, Cary, NC 27511, USA
    Vet Radiol Ultrasound 47:334-8. 2006