Research Topics
| Dahlia M NielsenSummaryAffiliation: North Carolina State University Country: USA Publications
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Detail Information
Publications
Association mapping: where we've been, where we're goingD M Nielsen
North Carolina State University, Program in Statistical Genetics, Department of Statistics, Raleigh, NC 27695 7566, USA
Expert Rev Mol Diagn 1:334-42. 2001..We describe the basis of association mapping and discuss a number of the commonly used techniques. We have also included references to various papers that have evaluated the use of these methods...
Effect of two- and three-locus linkage disequilibrium on the power to detect marker/phenotype associationsDahlia M Nielsen
Program in Statistical Genetics, Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695 7566, USA
Genetics 168:1029-40. 2004..Single-marker tests tend to prevail when pairwise LD is high. For moderate pairwise values and weak multilocus LD, either testing strategy may come out ahead, although it is also quite likely that neither has much power...
Does strong linkage disequilibrium guarantee redundant association results?Dahlia M Nielsen
Program in Statistical Genetics, Department of Genetics, North Carolina State University, Raleigh, NC 27695 7566, USA
Genet Epidemiol 32:546-52. 2008..In these cases, eliminating one of these markers from the set to be genotyped in an association study will lead to a reduction in overall power...
Proceedings of the First International Conference on Toxicogenomics Integrated with Environmental Sciences (TIES-2007)Pierre R Bushel
Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
BMC Proc 3:S1. 2009....
Measures of human population structure show heterogeneity among genomic regionsBruce S Weir
Program in Statistical Genetics, Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695 7566, USA
Genome Res 15:1468-76. 2005..Furthermore, it may be that the best indications of selection will come from population-specific F(ST) values rather than the usually reported population-average values...
Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in Heliconius eratoBrian A Counterman
Department of Genetics, North Carolina State University, Raleigh, North Carolina, United States of America
PLoS Genet 6:e1000796. 2010....
Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: signatures of genomic imbalance in canine osteosarcoma parallel the human counterpartAndrea Y Angstadt
Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, USA
Genes Chromosomes Cancer 50:859-74. 2011....
Genome-wide linkage study of atopic dermatitis in West Highland White TerriersCary A Salzmann
College of Veterinary Medicine, Department of Genetics, North Carolina State University, Raleigh, NC 27606, USA
BMC Genet 12:37. 2011..Microsatellite markers genotyped in families of WHWTs affected with AD were used to perform a genome-wide linkage study in order to isolate chromosomal regions associated with the disorder...
Comprehensive transcriptome profiling in tomato reveals a role for glycosyltransferase in Mi-mediated nematode resistanceJennifer E Schaff
Department of Plant Pathology, North Carolina State University, Raleigh, North Carolina 27695, USA
Plant Physiol 144:1079-92. 2007..Collectively, our data provide a picture of global gene expression changes in roots during compatible and incompatible associations with RKN, and point to candidates for further investigation...
