Karen R Munana

Summary

Affiliation: North Carolina State University
Country: USA

Publications

  1. ncbi Association between ABCB1 genotype and seizure outcome in collies with epilepsy
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Vet Intern Med 26:1358-64. 2012
  2. ncbi Evaluation of levetiracetam as adjunctive treatment for refractory canine epilepsy: a randomized, placebo-controlled, crossover trial
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Vet Intern Med 26:341-8. 2012
  3. ncbi Infection of fetal feline brain cells in culture with Bartonella henselae
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Infect Immun 69:564-9. 2001
  4. ncbi Beta-2-microglobulin levels in the cerebrospinal fluid of normal dogs and dogs with neurological disease
    Karen R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
    Vet Clin Pathol 36:173-8. 2007
  5. ncbi Placebo effect in canine epilepsy trials
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    J Vet Intern Med 24:166-70. 2010
  6. ncbi Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs
    Karen R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    J Am Vet Med Assoc 221:977-83. 2002
  7. ncbi Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs
    Erin M Kennerly
    Department of Genetics, Gardner Hall, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA
    Pharmacogenet Genomics 19:911-22. 2009
  8. ncbi Possible drug-induced hepatopathy in a dog receiving zonisamide monotherapy for treatment of cryptogenic epilepsy
    Malte Schwartz
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    J Vet Med Sci 73:1505-8. 2011
  9. ncbi Levetiracetam pharmacokinetics in healthy dogs following oral administration of single and multiple doses
    Sarah A Moore
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Am J Vet Res 71:337-41. 2010
  10. ncbi Assessment of the prevalence and clinical features of cryptogenic epilepsy in dogs: 45 cases (2003-2011)
    Malte Schwartz
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Am Vet Med Assoc 242:651-7. 2013

Collaborators

Detail Information

Publications12

  1. ncbi Association between ABCB1 genotype and seizure outcome in collies with epilepsy
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Vet Intern Med 26:1358-64. 2012
    ..Medically refractory seizures are an important problem in both humans and dogs with epilepsy. Altered expression of ABCB1, the gene encoding for p-glycoprotein (PGP), has been proposed to play a role in drug-resistant epilepsy...
  2. ncbi Evaluation of levetiracetam as adjunctive treatment for refractory canine epilepsy: a randomized, placebo-controlled, crossover trial
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Vet Intern Med 26:341-8. 2012
    ..There is little evidence-based information available to guide treatment of refractory epilepsy in dogs. The antiepileptic drug levetiracetam (LEV) is administered to dogs, although its safety and efficacy are unknown...
  3. ncbi Infection of fetal feline brain cells in culture with Bartonella henselae
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Infect Immun 69:564-9. 2001
    ..No evidence of infection was seen in Bartonella-inoculated astrocyte cultures. These findings suggest a role for microglia in the pathogenesis of B. henselae-associated neurological disease...
  4. ncbi Beta-2-microglobulin levels in the cerebrospinal fluid of normal dogs and dogs with neurological disease
    Karen R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
    Vet Clin Pathol 36:173-8. 2007
    ..Determination of CSF beta-2-microglobulin (beta2m) concentration has been used diagnostically in humans to identify inflammatory CNS disease; we hypothesized that it may have similar value in dogs...
  5. ncbi Placebo effect in canine epilepsy trials
    K R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    J Vet Intern Med 24:166-70. 2010
    ..The placebo effect is a well-recognized phenomenon in human medicine; in contrast, little information exists on the effect of placebo administration in veterinary patients...
  6. ncbi Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs
    Karen R Munana
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
    J Am Vet Med Assoc 221:977-83. 2002
    ..To evaluate safety and efficacy of vagal nerve stimulation in dogs with refractory epilepsy...
  7. ncbi Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs
    Erin M Kennerly
    Department of Genetics, Gardner Hall, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA
    Pharmacogenet Genomics 19:911-22. 2009
    ..Exploration of the genetic mechanisms involved in drug response may provide better treatment options for epileptic patients...
  8. ncbi Possible drug-induced hepatopathy in a dog receiving zonisamide monotherapy for treatment of cryptogenic epilepsy
    Malte Schwartz
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    J Vet Med Sci 73:1505-8. 2011
    ..Veterinary practitioners and owners should be educated about the potential for an idiosyncratic drug reaction to zonisamide. If signs of hepatotoxicity are recognised early and zonisamide is discontinued, complete recovery is possible...
  9. ncbi Levetiracetam pharmacokinetics in healthy dogs following oral administration of single and multiple doses
    Sarah A Moore
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Am J Vet Res 71:337-41. 2010
    ..To measure pharmacokinetics of levetiracetam (LEV) after single-dose oral administration in healthy dogs and determine whether pharmacokinetics changed after repeated oral dosing...
  10. ncbi Assessment of the prevalence and clinical features of cryptogenic epilepsy in dogs: 45 cases (2003-2011)
    Malte Schwartz
    Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Am Vet Med Assoc 242:651-7. 2013
    ..To determine the prevalence and clinical features of cryptogenic epilepsy among dogs...
  11. ncbi The cutaneous trunci muscle reflex: a predictor of recovery in dogs with acute thoracolumbar myelopathies caused by intervertebral disc extrusions
    Audrey C Muguet-Chanoit
    College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Vet Surg 41:200-6. 2012
    ..To determine whether changes in the cutaneous trunci muscle (CTM) reflex are an early predictor of outcome in dogs with severe acute thoracolumbar intervertebral disc extrusion (IVDE)...
  12. ncbi Imaging diagnosis--synchronous primary brain tumors in a dog
    Edward MacKillop
    Department of Clinical Sciences North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA
    Vet Radiol Ultrasound 48:550-3. 2007