G A LeBlanc

Summary

Affiliation: North Carolina State University
Country: USA

Publications

  1. ncbi request reprint Changes in the metabolic elimination profile of testosterone following exposure of the crustacean Daphnia magna to tributyltin
    G A LeBlanc
    Department of Toxicology, North Carolina State University, Raleigh, North Carolina 27695 7633, USA
    Ecotoxicol Environ Saf 45:296-303. 2000
  2. pmc Embryotoxicity of the alkylphenol degradation product 4-nonylphenol to the crustacean Daphnia magna
    G A LeBlanc
    Department of Toxicology, North Carolina State University, Raleigh, North Carolina 27695 7633, USA
    Environ Health Perspect 108:1133-8. 2000
  3. ncbi request reprint Crustacean endocrine toxicology: a review
    Gerald A LeBlanc
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695 7633, USA
    Ecotoxicology 16:61-81. 2007
  4. pmc Chronic toxicity of environmental contaminants: sentinels and biomarkers
    G A LeBlanc
    Department of Toxicology, North Carolina State University, Raleigh, USA
    Environ Health Perspect 105:65-80. 1997
  5. ncbi request reprint Biotransformation and disposition of testosterone in the eastern mud snail Ilyanassa obsoleta
    M P Gooding
    Department of Environmental and Molecular Toxicology, North Carolina State University, North Carolina, 27695-7633, USA
    Gen Comp Endocrinol 122:172-80. 2001
  6. ncbi request reprint The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna
    K Kast-Hutcheson
    Department of Toxicology, North Carolina State University, Raleigh 27695-7633, USA
    Environ Toxicol Chem 20:502-9. 2001
  7. ncbi request reprint Temporal and quantitative changes in sexual reproductive cycling of the cladoceran Daphnia magna by a juvenile hormone analog
    A W Olmstead
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695-7633, USA
    J Exp Zool 290:148-55. 2001
  8. ncbi request reprint Kinetic characterization of the inhibition of acyl coenzyme A: steroid acyltransferases by tributyltin in the eastern mud snail (Ilyanassa obsoleta)
    Robin M Sternberg
    Department of Environmental and Molecular Toxicology, North Carolina State University, Campus Box 7633, Raleigh, NC 27695, United States
    Aquat Toxicol 78:233-42. 2006
  9. ncbi request reprint Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways
    Xueyan Mu
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina 27695 7633, USA
    Environ Toxicol Chem 24:146-52. 2005
  10. ncbi request reprint Developmental toxicity of testosterone in the crustacean Daphnia magna involves anti-ecdysteroidal activity
    Xueyan Mu
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695 7633 USA
    Gen Comp Endocrinol 129:127-33. 2002

Collaborators

  • Susan Jobling
  • Xueyan Mu
  • Bethany R Hannas
  • D Andrew Crain
  • Robin M Sternberg
  • A W Olmstead
  • M P Gooding
  • K Kast-Hutcheson
  • Louis J Guillette
  • Taisen Iguchi
  • Marcus Eriksen
  • Hans Laufer
  • Heather Hoy
  • Cynthia V Rider
  • Gap Soo Hwang
  • C V Rider

Detail Information

Publications12

  1. ncbi request reprint Changes in the metabolic elimination profile of testosterone following exposure of the crustacean Daphnia magna to tributyltin
    G A LeBlanc
    Department of Toxicology, North Carolina State University, Raleigh, North Carolina 27695 7633, USA
    Ecotoxicol Environ Saf 45:296-303. 2000
    ....
  2. pmc Embryotoxicity of the alkylphenol degradation product 4-nonylphenol to the crustacean Daphnia magna
    G A LeBlanc
    Department of Toxicology, North Carolina State University, Raleigh, North Carolina 27695 7633, USA
    Environ Health Perspect 108:1133-8. 2000
    ..However, these effects do occur at sufficiently low levels to warrant evaluation of the relative susceptibility of other crustacean species to this previously uncharacterized mode of toxicity...
  3. ncbi request reprint Crustacean endocrine toxicology: a review
    Gerald A LeBlanc
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695 7633, USA
    Ecotoxicology 16:61-81. 2007
    ..e., temperature, parasitism) also can elicit these effects and definitive causal relationships between endocrine disruption in field populations of crustaceans and chemical pollution is generally lacking...
  4. pmc Chronic toxicity of environmental contaminants: sentinels and biomarkers
    G A LeBlanc
    Department of Toxicology, North Carolina State University, Raleigh, USA
    Environ Health Perspect 105:65-80. 1997
    ..The incorporation of appropriate surrogate species and biomarkers of chronic toxicity into standard toxicity characterizations is proposed as a means of significantly refining the ecological hazard assessment process...
  5. ncbi request reprint Biotransformation and disposition of testosterone in the eastern mud snail Ilyanassa obsoleta
    M P Gooding
    Department of Environmental and Molecular Toxicology, North Carolina State University, North Carolina, 27695-7633, USA
    Gen Comp Endocrinol 122:172-80. 2001
    ..The esterification of testosterone to fatty acids might be a mechanism where by steroid titers are regulated and could represent a target of TBT toxicity...
  6. ncbi request reprint The fungicide propiconazole interferes with embryonic development of the crustacean Daphnia magna
    K Kast-Hutcheson
    Department of Toxicology, North Carolina State University, Raleigh 27695-7633, USA
    Environ Toxicol Chem 20:502-9. 2001
    ..These results indicate that propiconazole interferes with the later stages of daphnid embryonic development, and that this toxicity is manifested largely via maternal exposure to the fungicide...
  7. ncbi request reprint Temporal and quantitative changes in sexual reproductive cycling of the cladoceran Daphnia magna by a juvenile hormone analog
    A W Olmstead
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695-7633, USA
    J Exp Zool 290:148-55. 2001
    ..J. Exp. Zool. 290:148-155, 2001...
  8. ncbi request reprint Kinetic characterization of the inhibition of acyl coenzyme A: steroid acyltransferases by tributyltin in the eastern mud snail (Ilyanassa obsoleta)
    Robin M Sternberg
    Department of Environmental and Molecular Toxicology, North Carolina State University, Campus Box 7633, Raleigh, NC 27695, United States
    Aquat Toxicol 78:233-42. 2006
    ....
  9. ncbi request reprint Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways
    Xueyan Mu
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina 27695 7633, USA
    Environ Toxicol Chem 24:146-52. 2005
    ..However, effects are elicited at levels that are not likely to pose environmental concern...
  10. ncbi request reprint Developmental toxicity of testosterone in the crustacean Daphnia magna involves anti-ecdysteroidal activity
    Xueyan Mu
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695 7633 USA
    Gen Comp Endocrinol 129:127-33. 2002
    ..testosterone elicits embryo toxicity to daphnids by interfering with ecdysteroid activity, and (3). ecdysteroid receptor antagonism could be one mechanism by which testosterone elicits these effects...
  11. pmc Expression and ecdysteroid responsiveness of the nuclear receptors HR3 and E75 in the crustacean Daphnia magna
    Bethany R Hannas
    Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC 27695 7633, USA
    Mol Cell Endocrinol 315:208-18. 2010
    ..The marginal induction of E75 by 20-hydroxyecdysone may represent limited, tissue or cell-type-specific induction of this transcription factor...
  12. ncbi request reprint An ecological assessment of bisphenol-A: evidence from comparative biology
    D Andrew Crain
    Department of Biology, Maryville College, 502 E Lamar Alexander Parkway, Maryville, TN 37804 5907, USA
    Reprod Toxicol 24:225-39. 2007
    ..Further studies should examine the most vulnerable vertebrate and invertebrate species...