Teresa L Leavens

Summary

Affiliation: North Carolina State University
Country: USA

Publications

  1. pmc In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps
    Teresa L Leavens
    Center for Chemical Toxicology Research and Pharmacokinetics, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Appl Toxicol 32:913-9. 2012
  2. doi request reprint Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats
    T L Leavens
    Center for Chemical Toxicology Research and Pharmacokinetics, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27709, USA
    J Vet Pharmacol Ther 35:121-31. 2012
  3. doi request reprint Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles
    Teresa L Leavens
    Center for Chemical Toxicology Research and Pharmacokinetics, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, United States
    Toxicol Lett 197:1-6. 2010
  4. ncbi request reprint Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats
    Jessica Romanet
    Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Am J Vet Res 73:1634-40. 2012
  5. pmc Acute vascular effects of nanoparticle infusion in isolated perfused skin
    Jim E Riviere
    Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, Raleigh, NC, USA
    Nanomedicine 8:428-31. 2012
  6. doi request reprint Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats
    Gabrielle Young
    Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Res Vet Sci 90:477-9. 2011
  7. doi request reprint Comparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model
    Hyun A Lee
    College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Nano Lett 9:794-9. 2009

Collaborators

Detail Information

Publications7

  1. pmc In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps
    Teresa L Leavens
    Center for Chemical Toxicology Research and Pharmacokinetics, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA
    J Appl Toxicol 32:913-9. 2012
    ..Four hours after infusion of the Ag nanoparticles, the recovery of Ag in the venous effluent was 90 ± 5.0% and 87 ± 22% of the infused Ag for Ag-citrate and Ag-silica, respectively...
  2. doi request reprint Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats
    T L Leavens
    Center for Chemical Toxicology Research and Pharmacokinetics, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27709, USA
    J Vet Pharmacol Ther 35:121-31. 2012
    ..The developed model and compilation of physiological parameters for goats provide initial tools that can be used as a basis for predicting withdrawal times of drugs in this minor species...
  3. doi request reprint Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles
    Teresa L Leavens
    Center for Chemical Toxicology Research and Pharmacokinetics, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, United States
    Toxicol Lett 197:1-6. 2010
    ....
  4. ncbi request reprint Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats
    Jessica Romanet
    Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Am J Vet Res 73:1634-40. 2012
    ..To determine the tissue depletion profile of tulathromycin and determine an appropriate slaughter withdrawal interval in meat goats after multiple SC injections of the drug...
  5. pmc Acute vascular effects of nanoparticle infusion in isolated perfused skin
    Jim E Riviere
    Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, Raleigh, NC, USA
    Nanomedicine 8:428-31. 2012
    ..In contrast, infusion with nC(60) nanoparticles did not produce these effects. These observations suggest certain nanoparticle infusions may be associated with acute vascular physiologic effects that merit further attention...
  6. doi request reprint Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats
    Gabrielle Young
    Food Animal Residue Avoidance Databank, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
    Res Vet Sci 90:477-9. 2011
    ..In this study, it was determined that the pharmacokinetics of tulathromycin after a single 2.5 mg/kg SC injection in goats were very similar to what has been previously reported in cattle...
  7. doi request reprint Comparison of quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model
    Hyun A Lee
    College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Nano Lett 9:794-9. 2009
    ..The model predicted the experimentally observed persistence of QDs in tissues but not early time profiles or different QD biodistribution. Therefore, more complex models will be needed to better predict QD biodistribution in vivo...