Katherine H Karlsgodt

Summary

Affiliation: North Shore University Hospital
Country: USA

Publications

  1. doi White matter microstructure in the executive network associated with aggression in healthy adolescents and young adults
    Katherine H Karlsgodt
    Feinstein Institute for Medical Research, Manhasset NY, Zucker Hillside Hospital, Glen Oaks NY, and Hofstra NorthShore LIJ School of Medicine, Hempstead NY, USA
    Soc Cogn Affect Neurosci 10:1251-6. 2015
  2. pmc Disrupted working memory circuitry and psychotic symptoms in 22q11.2 deletion syndrome
    C A Montojo
    Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, University of California, Los Angeles, Los Angeles, CA 90095, USA Department of Psychology, 1285 Franz Hall, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Neuroimage Clin 4:392-402. 2014
  3. pmc Altered relationships between age and functional brain activation in adolescents at clinical high risk for psychosis
    Katherine H Karlsgodt
    Department of Psychiatry, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA Feinstein Institute for Medical Research, Manhasset, NY, USA Electronic address
    Psychiatry Res 221:21-9. 2014
  4. pmc Alterations in white matter microstructure in neurofibromatosis-1
    Katherine H Karlsgodt
    Semel Institute for Neuroscience and Behavior, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 7:e47854. 2012
  5. pmc Symptomatic and functional correlates of regional brain physiology during working memory processing in patients with recent onset schizophrenia
    Jacqueline H Sanz
    Department of Psychology, University of California Los Angeles, Los Angeles, CA 90095, United States
    Psychiatry Res 173:177-82. 2009
  6. ncbi Diffusion tensor imaging of the superior longitudinal fasciculus and working memory in recent-onset schizophrenia
    Katherine H Karlsgodt
    Department of Psychology, University of California, Los Angeles, California 90095 1563, USA
    Biol Psychiatry 63:512-8. 2008
  7. pmc Re-evaluating dorsolateral prefrontal cortex activation during working memory in schizophrenia
    Katherine H Karlsgodt
    Department of Psychology, UCLA, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095 1563, USA
    Schizophr Res 108:143-50. 2009
  8. pmc A multimodal assessment of the genetic control over working memory
    Katherine H Karlsgodt
    Department of Psychiatry, Cognitive Neuroscience Center, University of California Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 30:8197-202. 2010
  9. pmc Genetic architecture of declarative memory: implications for complex illnesses
    Carrie E Bearden
    Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA
    Neuroscientist 18:516-32. 2012
  10. pmc Neurofibromin regulates corticostriatal inhibitory networks during working memory performance
    Carrie Shilyansky
    Department of Neurobiology, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:13141-6. 2010

Collaborators

Detail Information

Publications26

  1. doi White matter microstructure in the executive network associated with aggression in healthy adolescents and young adults
    Katherine H Karlsgodt
    Feinstein Institute for Medical Research, Manhasset NY, Zucker Hillside Hospital, Glen Oaks NY, and Hofstra NorthShore LIJ School of Medicine, Hempstead NY, USA
    Soc Cogn Affect Neurosci 10:1251-6. 2015
    ..This has implications for our healthy behavior understanding of as well as that of patient populations known to have executive dysfunction. ..
  2. pmc Disrupted working memory circuitry and psychotic symptoms in 22q11.2 deletion syndrome
    C A Montojo
    Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, University of California, Los Angeles, Los Angeles, CA 90095, USA Department of Psychology, 1285 Franz Hall, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Neuroimage Clin 4:392-402. 2014
    ..These results suggest that 22q11DS patients show reduced neural recruitment of brain regions critical for spatial WM function, which may be related to characteristic behavioral manifestations of the disorder. ..
  3. pmc Altered relationships between age and functional brain activation in adolescents at clinical high risk for psychosis
    Katherine H Karlsgodt
    Department of Psychiatry, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA Feinstein Institute for Medical Research, Manhasset, NY, USA Electronic address
    Psychiatry Res 221:21-9. 2014
    ..Finding that age related variation in baseline patterns of neural activity differentiate individuals who subsequently convert to psychosis from healthy subjects suggests that these differences are likely to be clinically relevant. ..
  4. pmc Alterations in white matter microstructure in neurofibromatosis-1
    Katherine H Karlsgodt
    Semel Institute for Neuroscience and Behavior, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 7:e47854. 2012
    ..Further, this indicates that axial and radial diffusivity can uniquely contribute as markers of NF1-associated brain pathology in conjunction with the typically investigated measures...
  5. pmc Symptomatic and functional correlates of regional brain physiology during working memory processing in patients with recent onset schizophrenia
    Jacqueline H Sanz
    Department of Psychology, University of California Los Angeles, Los Angeles, CA 90095, United States
    Psychiatry Res 173:177-82. 2009
    ....
  6. ncbi Diffusion tensor imaging of the superior longitudinal fasciculus and working memory in recent-onset schizophrenia
    Katherine H Karlsgodt
    Department of Psychology, University of California, Los Angeles, California 90095 1563, USA
    Biol Psychiatry 63:512-8. 2008
    ....
  7. pmc Re-evaluating dorsolateral prefrontal cortex activation during working memory in schizophrenia
    Katherine H Karlsgodt
    Department of Psychology, UCLA, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095 1563, USA
    Schizophr Res 108:143-50. 2009
    ....
  8. pmc A multimodal assessment of the genetic control over working memory
    Katherine H Karlsgodt
    Department of Psychiatry, Cognitive Neuroscience Center, University of California Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 30:8197-202. 2010
    ....
  9. pmc Genetic architecture of declarative memory: implications for complex illnesses
    Carrie E Bearden
    Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA
    Neuroscientist 18:516-32. 2012
    ..And finally we review evidence from both complex and single-gene disorders, which provide insight into the molecular mechanisms underlying the genetic basis of human memory function...
  10. pmc Neurofibromin regulates corticostriatal inhibitory networks during working memory performance
    Carrie Shilyansky
    Department of Neurobiology, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:13141-6. 2010
    ..Collectively, these integrative mouse and human studies reveal molecular and cellular mechanisms contributing to working memory deficits in NF1...
  11. pmc Remember and know judgments during recognition in chronic schizophrenia
    Theo G M van Erp
    Department of Psychology, UCLA, Los Angeles, CA 90095, USA
    Schizophr Res 100:181-90. 2008
    ..Taken together, these findings are consistent with a deficit in recollection and increased reliance on familiarity in making recognition memory judgments in chronic schizophrenia...
  12. doi The accumbofrontal tract: Diffusion tensor imaging characterization and developmental change from childhood to adulthood
    Katherine H Karlsgodt
    Zucker Hillside Hospital, Glen Oaks, New York
    Hum Brain Mapp 36:4954-63. 2015
    ..Hum Brain Mapp 36:4954-4963, 2015. © 2015 Wiley Periodicals, Inc. ..
  13. pmc Altered age-related trajectories of amygdala-prefrontal circuitry in adolescents at clinical high risk for psychosis: a preliminary study
    Dylan G Gee
    University of California, Los Angeles, Department of Psychology, Los Angeles, CA 90095 1563, USA
    Schizophr Res 134:1-9. 2012
    ..Longitudinal data are needed to confirm aberrant developmental trajectories intra-individually and to examine whether these abnormalities are predictive of conversion to psychosis, and of later deficits in socioemotional functioning...
  14. doi Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia
    Katherine H Karlsgodt
    Department of Psychology, 1285 Franz Hall Box 951563, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    Dev Psychopathol 20:1297-327. 2008
    ....
  15. pmc Genetic influence on the working memory circuitry: behavior, structure, function and extensions to illness
    Katherine H Karlsgodt
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, USA
    Behav Brain Res 225:610-22. 2011
    ..This has implications for our understanding of the transmission of working memory deficits in both healthy and disordered populations...
  16. ncbi The relationship between performance and fMRI signal during working memory in patients with schizophrenia, unaffected co-twins, and control subjects
    Katherine H Karlsgodt
    Department of Psychology, UCLA, Los Angeles, CA 90095 1563, USA
    Schizophr Res 89:191-7. 2007
    ..Further, this study offers preliminary evidence that the relationship between behavior and physiology in schizophrenia may be heritable...
  17. pmc Brain white matter development is associated with a human-specific haplotype increasing the synthesis of long chain fatty acids
    Bart D Peters
    Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York 11004, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario M5T 1R8, Canada, Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada, Department of Psychiatry, University of Toronto, Toronto, Ontario M5T 1R8, Canada, Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, New York 11030, and Department of Communication Sciences and Disorders, School of Applied Sciences, University of Mississippi, University, Mississippi 38766
    J Neurosci 34:6367-76. 2014
    ..05). These findings suggest that LC-PUFAs are involved in human brain WM development from childhood into adulthood. This haplotype and LC-PUFAs may play a role in myelin-related disorders of neurodevelopmental origin...
  18. pmc Adding insult to injury: childhood and adolescent risk factors for psychosis predict lower fractional anisotropy in the superior longitudinal fasciculus in healthy adults
    Pamela DeRosse
    Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Manhasset, NY, USA Division of Psychiatry Research, The Zucker Hillside Hospital, Division of the North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA Electronic address
    Psychiatry Res 224:296-302. 2014
    ..Prospective longitudinal studies examining the effect of risk factors on the developmental trajectory of brain WM are warranted. ..
  19. doi Structural and functional neuroimaging phenotypes in dysbindin mutant mice
    Evan Lutkenhoff
    Interdisciplinary Neuroscience Program, University of California, Los Angeles, CA 90095, USA
    Neuroimage 62:120-9. 2012
    ..It revealed both hypothesized and novel structural and functional neural alterations related to dysbindin-1...
  20. pmc Reduced dysbindin expression mediates N-methyl-D-aspartate receptor hypofunction and impaired working memory performance
    Katherine H Karlsgodt
    Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 69:28-34. 2011
    ..At a cellular level, dysbindin is thought to mediate presynaptic glutamatergic transmission...
  21. doi Baseline Striatal Functional Connectivity as a Predictor of Response to Antipsychotic Drug Treatment
    Deepak K Sarpal
    From the Department of Psychiatry, Zucker Hillside Hospital, North Shore LIJ Health System, Glen Oaks, N Y the Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, N Y the Department of Psychiatry, Hofstra North Shore LIJ School of Medicine, Hempstead, N Y and the Department of Mathematics, Hofstra University, Hempstead, N Y
    Am J Psychiatry 173:69-77. 2016
    ..The goal of the present study was to test whether intrinsic striatal connectivity patterns provide prognostic information and can serve as a potential biomarker of treatment response to antipsychotic drugs...
  22. pmc Default mode network connectivity and reciprocal social behavior in 22q11.2 deletion syndrome
    Matthew J Schreiner
    Interdepartmental Neuroscience Program, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095, Department of Psychiatry, Feinstein Institute for Medical Research, Manhasset, NY 11030, Zucker Hillside Hospital, Glen Oaks, NY 11004, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 and Department of Psychology, University of California, Los Angeles, CA 90095, USA Interdepartmental Neuroscience Program, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095, Department of Psychiatry, Feinstein Institute for Medical Research, Manhasset, NY 11030, Zucker Hillside Hospital, Glen Oaks, NY 11004, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 and Department of Psychology, University of California, Los Angeles, CA 90095, USA
    Soc Cogn Affect Neurosci 9:1261-7. 2014
    ..Increased strength of long-range DMN connectivity was associated with improved social functioning in 22q11DS. These findings support a 'developmental-disconnection' hypothesis of symptom development in this disorder. ..
  23. pmc Neural activation during response inhibition in adult attention-deficit/hyperactivity disorder: preliminary findings on the effects of medication and symptom severity
    Eliza Congdon
    Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, USA Electronic address
    Psychiatry Res 222:17-28. 2014
    ..These findings help to explain some of the disparities in the literature, and advance our understanding of why deficits in response inhibition are more variable in adult, as compared with child and adolescent, ADHD patients. ..
  24. ncbi The relationship of developmental changes in white matter to the onset of psychosis
    Katherine H Karlsgodt
    Semel Institute for Neuroscience and Behavior, University of California, Los Angeles, CA, USA
    Curr Pharm Des 18:422-33. 2012
    ..Finally, we discuss the implications of these findings for future research directions and for potential therapeutic interventions...
  25. ncbi Hippocampal activations during encoding and retrieval in a verbal working memory paradigm
    Katherine H Karlsgodt
    Department of Psychology, UCLA, 1285 Franz Hall, Los Angeles, CA 90095 1563, USA
    Neuroimage 25:1224-31. 2005
    ....
  26. pmc White matter development in the early stages of psychosis
    Bart D Peters
    Division of Psychiatry Research, Zucker Hillside Hospital, Northshore LIJ Health System, Glen Oaks, NY, United States
    Schizophr Res 161:61-9. 2015
    ..Discovery of the factors driving healthy white matter development across the lifespan and deviations from the normal developmental trajectory may provide insights relevant to the discovery of early treatment interventions. ..