M S Ashwell

Summary

Affiliation: North Carolina State University
Country: USA

Publications

  1. ncbi request reprint Detection of quantitative trait loci influencing conformation traits and calving ease in Holstein-Friesian cattle
    M S Ashwell
    Department of Animal Science, North Carolina State University, Raleigh 27695, USA
    J Dairy Sci 88:4111-9. 2005
  2. doi request reprint Amount and source of dietary copper affects small intestine morphology, duodenal lipid peroxidation, hepatic oxidative stress,and mRNA expression of hepatic copper regulatory proteins in weanling pigs
    R S Fry
    North Carolina State University, Raleigh 27695, USA
    J Anim Sci 90:3112-9. 2012
  3. doi request reprint High dietary iron reduces transporters involved in iron and manganese metabolism and increases intestinal permeability in calves
    S L Hansen
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695 7621, USA
    J Dairy Sci 93:656-65. 2010
  4. doi request reprint Investigation of breed and sex effects on cytochrome P450 gene expression in cattle liver
    M S Ashwell
    Department of Animal Science, North Carolina State University, Campus Box 7621, Raleigh, NC 27695 7621, USA
    Res Vet Sci 90:235-7. 2011
  5. doi request reprint Effect of dietary copper and breed on gene products involved in copper acquisition, distribution, and use in Angus and Simmental cows and fetuses
    R S Fry
    Department of Animal Science, North Carolina State University, Raleigh 27695, USA
    J Anim Sci 91:861-71. 2013
  6. doi request reprint Gene expression profiling of chondrocytes from a porcine impact injury model
    M S Ashwell
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695, United States
    Osteoarthritis Cartilage 16:936-46. 2008
  7. ncbi request reprint Refinement of quantitative trait loci on bovine chromosome 18 affecting health and reproduction in US Holsteins
    S A Muncie
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695, USA
    Anim Genet 37:273-5. 2006
  8. ncbi request reprint Characterization of a line of pigs previously selected for increased litter size for RBP4 and follistatin
    C D Blowe
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695 7621, USA
    J Anim Breed Genet 123:389-95. 2006
  9. doi request reprint Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
    S L Hansen
    Department of Animal Science, North Carolina State University, Raleigh 27695 7621, USA
    J Anim Sci 88:275-83. 2010
  10. ncbi request reprint Mapping quantitative trait loci affecting dairy conformation to chromosome 27 in two Holstein grandsire families
    C P Van Tassell
    Bovine Functional Genomics Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    J Dairy Sci 87:450-7. 2004

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Detection of quantitative trait loci influencing conformation traits and calving ease in Holstein-Friesian cattle
    M S Ashwell
    Department of Animal Science, North Carolina State University, Raleigh 27695, USA
    J Dairy Sci 88:4111-9. 2005
    ..Additional work is needed to determine the precise locations of the QTL and select positional candidate genes influencing these traits...
  2. doi request reprint Amount and source of dietary copper affects small intestine morphology, duodenal lipid peroxidation, hepatic oxidative stress,and mRNA expression of hepatic copper regulatory proteins in weanling pigs
    R S Fry
    North Carolina State University, Raleigh 27695, USA
    J Anim Sci 90:3112-9. 2012
    ..Feeding weanling pigs increased Cu resulted in modulation of certain Cu transporters and chaperones at the transcription level...
  3. doi request reprint High dietary iron reduces transporters involved in iron and manganese metabolism and increases intestinal permeability in calves
    S L Hansen
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695 7621, USA
    J Dairy Sci 93:656-65. 2010
    ..Additionally, reduced levels of DMT1 protein appeared to decrease duodenal Mn, suggesting that Mn may also be a substrate for DMT1 in cattle...
  4. doi request reprint Investigation of breed and sex effects on cytochrome P450 gene expression in cattle liver
    M S Ashwell
    Department of Animal Science, North Carolina State University, Campus Box 7621, Raleigh, NC 27695 7621, USA
    Res Vet Sci 90:235-7. 2011
    ..Therefore breed and/or sex of an animal may need to be considered before administering a dose of a xenobiotic due to the potential for harmful drug residues in foodstuffs as well as improper treatment of disease conditions...
  5. doi request reprint Effect of dietary copper and breed on gene products involved in copper acquisition, distribution, and use in Angus and Simmental cows and fetuses
    R S Fry
    Department of Animal Science, North Carolina State University, Raleigh 27695, USA
    J Anim Sci 91:861-71. 2013
    ..Up-regulation of fetal liver Atox1, Cox17, and Commd1 in-Cu fetuses may reflect the great Cu demand by the fetus...
  6. doi request reprint Gene expression profiling of chondrocytes from a porcine impact injury model
    M S Ashwell
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695, United States
    Osteoarthritis Cartilage 16:936-46. 2008
    ..To identify differentially expressed genes between axially impacted and control articular cartilage taken from porcine patellae maintained in organ culture for 14 days...
  7. ncbi request reprint Refinement of quantitative trait loci on bovine chromosome 18 affecting health and reproduction in US Holsteins
    S A Muncie
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695, USA
    Anim Genet 37:273-5. 2006
    ..Analysis of the extended pedigree detected significant and suggestive QTL for DPR, productive life and somatic cell score. Further analysis is underway to refine the QTL region so that positional candidate genes can be identified...
  8. ncbi request reprint Characterization of a line of pigs previously selected for increased litter size for RBP4 and follistatin
    C D Blowe
    Department of Animal Science, North Carolina State University, Raleigh, NC 27695 7621, USA
    J Anim Breed Genet 123:389-95. 2006
    ..No significant additive or dominance effects of the FS markers were detected for NFF, NBA and MUM in either LS or LC. Response to selection for increased litter size could not be attributed to effects at the ESR, RBP4 or FS loci...
  9. doi request reprint Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
    S L Hansen
    Department of Animal Science, North Carolina State University, Raleigh 27695 7621, USA
    J Anim Sci 88:275-83. 2010
    ..However, the addition of 500 mg of Mn/kg of DM to a diet low in Cu reduced duodenal expression of the Fe import protein DMT1...
  10. ncbi request reprint Mapping quantitative trait loci affecting dairy conformation to chromosome 27 in two Holstein grandsire families
    C P Van Tassell
    Bovine Functional Genomics Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    J Dairy Sci 87:450-7. 2004
    ..Identification of quantitative trait loci affecting dairy conformation and fat components supports results reported by other groups, providing additional evidence that genes affecting fat metabolism are located on bovine chromosome 27...
  11. ncbi request reprint Whole-genome scan to detect QTL for milk production, conformation, fertility and functional traits in two US Holstein families
    R D Schnabel
    Bovine Functional Genomics Laboratory, USDA ARS, Beltsville, MD 20705, USA
    Anim Genet 36:408-16. 2005
    ..A total of 47 tests achieved at least genome-wise significance. However, results from the two methods of analysis were only concordant for QTL location and level of significance in eight instances...
  12. ncbi request reprint An expanded comparative map of bovine chromosome 27 targeting dairy form QTL regions
    E E Connor
    U S Beltsville Agricultural Research Center, ARS, USDA, 10300 Baltimore Ave, Beltsville, MD 20705, USA
    Anim Genet 35:265-9. 2004
    ..1 region and BTA8. These data increase the number of genes positioned on the bovine gene maps, refine the human-bovine comparative map, and should improve the efficiency of candidate gene selection for the dairy form trait in cattle...
  13. ncbi request reprint Detection of quantitative trait loci affecting milk production, health, and reproductive traits in Holstein cattle
    M S Ashwell
    United States Department of Agriculture Agricultural Research Service, Bovine Functional Genomics Laboratory, Beltsville, MD 20705, USA
    J Dairy Sci 87:468-75. 2004
    ..These findings may help identify the most useful markers available for QTL detection and, eventually, for marker-assisted selection for improvement of these economically important traits...
  14. ncbi request reprint Comparative mapping of bovine chromosome 27 with human chromosome 8 near a dairy form QTL in cattle
    E E Connor
    Beltsville Agricultural Research Center, ARS, USDA, Beltsville, MD 20705, USA
    Cytogenet Genome Res 112:98-102. 2006
    ..Further studies are underway to investigate the existence of polymorphisms in the bovine ADRB3 gene and their association with traits related to fat deposition in cattle...
  15. ncbi request reprint Genetic diversity and background linkage disequilibrium in the North American Holstein cattle population
    R L Vallejo
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park 16802, USA
    J Dairy Sci 86:4137-47. 2003
    ..These results suggest that the observed LD is not purely due to genetic drift and migration and that a portion might be due to DLD. This raises our hopes of successful fine-localization of genes for complex traits using LD mapping...
  16. ncbi request reprint Physical and linkage mapping of mammary-derived expressed sequence tags in cattle
    E E Connor
    U S Beltsville Agricultural Research Center, ARS, U S Department of Agriculture, Beltsville, MD 20705, USA
    Genomics 83:148-52. 2004
    ..Overall, these data improve the resolution of the human-bovine comparative maps and will assist future efforts to integrate bovine RH and linkage map data...
  17. ncbi request reprint Characterization and expression of the bovine growth hormone-releasing hormone (GHRH) receptor
    E E Connor
    Agricultural Research Service, USDA, Beltsville, MD 20705, USA
    Domest Anim Endocrinol 22:189-200. 2002
    ..In the present study, bST treatment of dairy heifers resulted in no significant decline in pituitary GHRH receptor expression...
  18. ncbi request reprint Isolation, characterization and mapping of the bovine signal peptidase subunit 18 gene
    M S Ashwell
    USDA ARS, Beltsville Agricultural Research Center, Beltsville, MD, USA
    Anim Genet 32:232-3. 2001
  19. ncbi request reprint Comparative map alignment of BTA27 and HSA4 and 8 to identify conserved segments of genome containing fat deposition QTL
    T S Sonstegard
    ARS USDA Gene Evaluation and Mapping Laboratory, Beltsville Agricultural Research Center BARC, Bdlg 200 Rm 2A, BARC East, Beltsville, Maryland 20705, USA
    Mamm Genome 11:682-8. 2000
    ..Comparative map alignment strongly suggests the conserved segment orthologous to HSA8p21-q11 contains QTL for fat deposition in cattle...