Research Topics
| Craig AltierSummaryAffiliation: North Carolina State University Country: USA Publications
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Detail Information
Publications
A recombinase-based selection of differentially expressed bacterial genesC Altier
Department of Microbiology, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough St, Raleigh, NC, USA
Gene 240:99-106. 1999..typhimurium genes that are specifically expressed when bacteria interact with cultured epithelial cells and identified a novel DNA fragment, not found in E. coli, which might represent part of a new pathogenicity island...
Genetic and environmental control of salmonella invasionCraig Altier
College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
J Microbiol 43:85-92. 2005..This review will discuss the current understanding of invasion control, with emphasis on the interaction of environmental factors with genetic regulators that leads to productive infection...
Regulation of Salmonella enterica serovar typhimurium invasion genes by csrAC Altier
Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
Infect Immun 68:6790-7. 2000....
Characterization of antimicrobial-resistant phenotypes and genotypes among Salmonella enterica recovered from pigs on farms, from transport trucks, and from pigs after slaughterWondwossen A Gebreyes
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
J Food Prot 67:698-705. 2004..Class I integrons were also common among various serovars...
Trends in antimicrobial resistance, phage types and integrons among Salmonella serotypes from pigs, 1997-2000Wondwossen A Gebreyes
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
J Antimicrob Chemother 53:997-1003. 2004..The objectives of this study were to determine antimicrobial resistance and to identify phage types and class 1 integrons among non-typhoidal Salmonella isolates from 24 pig farms in North Carolina collected between 1997 and 2000...
Genome-wide screen of Salmonella genes expressed during infection in pigs, using in vivo expression technologyYanyan Huang
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Appl Environ Microbiol 73:7522-30. 2007..High temperature and increased osmolarity were identified as environmental signals that induced in vivo-expressed genes, suggesting possible signals for expression...
Global regulation by CsrA in Salmonella typhimuriumSara D Lawhon
College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh 27606, USA
Mol Microbiol 48:1633-45. 2003....
Intestinal short-chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirASara D Lawhon
Department of Microbiology, Pathology and Parasitology, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Mol Microbiol 46:1451-64. 2002..These results suggest that the concentration and composition of SCFAs in the distal ileum provide a signal for productive infection by Salmonella, whereas those of the large intestine inhibit invasion...
Characterization of two novel regulatory genes affecting Salmonella invasion gene expressionC Altier
Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Mol Microbiol 35:635-46. 2000....
Identification of CsrC and characterization of its role in epithelial cell invasion in Salmonella enterica serovar TyphimuriumDoreen R Fortune
College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
Infect Immun 74:331-9. 2006..Similarly, the overexpression of csrA increased CsrC by nearly 11-fold and CsrB by 3-fold and also significantly increased the stability of both RNAs...
Molecular epidemiology and diversity of Salmonella serovar Typhimurium in pigs using phenotypic and genotypic approachesW A Gebreyes
Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, NC 27606, USA
Epidemiol Infect 134:187-98. 2006..Clonal types obtained from nursery farms and corresponding finishing units were, however, similar...
Salmonella enterica serovars from pigs on farms and after slaughter and validity of using bacteriologic data to define herd Salmonella statusWondwossen A Gebreyes
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
J Food Prot 67:691-7. 2004..The findings further imply that slaughter plant studies based on phenotyping of Salmonella alone (such as serovars) may not reliably indicate the Salmonella status of commercial swine farms...
Molecular characterization of multidrug-resistant Salmonella enterica subsp. enterica serovar Typhimurium isolates from swineWondwossen Abebe Gebreyes
Department of Farm Animal Health Resources Management, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
J Clin Microbiol 40:2813-22. 2002....
Effect of stacking method on Salmonella elimination from recycled poultry beddingDawn J Bush
College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, United States
Bioresour Technol 98:571-8. 2007..Ammonia concentration in the RPB was highest at the top of the DS-RPB. Salmonella was eliminated in 98.7% of sites, with at least a 5-log reduction in the Salmonella organisms in sites where it was still viable...
In vitro and in vivo assessment of Salmonella enterica serovar Typhimurium DT104 virulenceC A Allen
Department of Microbiology, North Carolina State University, Raleigh, North Carolina 27695
Infect Immun 69:4673-7. 2001..Our results failed to demonstrate that S. enterica serovar Typhimurium DT104 isolates are more virulent than S. enterica serovar Typhimurium ATCC 14028s...
In utero infection by porcine reproductive and respiratory syndrome virus is sufficient to increase susceptibility of piglets to challenge by Streptococcus suis type IIW Feng
Department of Farm Animal Health and Resource Management, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
J Virol 75:4889-95. 2001..suis type II. In utero infection by PRRSV may provide a useful model to study the interaction between PRRSV and bacterial coinfections in piglets...
Formate acts as a diffusible signal to induce Salmonella invasionYanyan Huang
Department of Population Medicine and Diagnostic Sciences, Upper Tower Road, Cornell University, Ithaca, NY 14853, USA
J Bacteriol 190:4233-41. 2008..Furthermore, we found that formate affected the major regulators of SPI1, hilA and hilD, but that the primary routes of formate metabolism played no role in its activity as a signal...
SdiA, an N-acylhomoserine lactone receptor, becomes active during the transit of Salmonella enterica through the gastrointestinal tract of turtlesJenee N Smith
Department of Microbiology, The Ohio State University, Columbus, Ohio, United States of America
PLoS ONE 3:e2826. 2008..However, while Escherichia and Salmonella encode a LuxR-type AHL receptor, SdiA, they cannot synthesize AHLs. In vitro, it is known that SdiA can detect AHLs produced by other bacterial species...
Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNANa Lin
Department of Chemistry and Center for Biotechnology and Drug Design, Campus Box 4098, Georgia State University, Atlanta, GA 30302 4098, USA
Nucleic Acids Res 35:1222-9. 2007..DNA polymerase recognitions of the B-TTP as a substrate and the boronic acid-labeled DNA as a template are critical issues for the development of DNA-based lectin mimics via in vitro selection...
Persistent urinary tract infections and reinfections in 100 dogs (1989-1999)M Alexis Seguin
Mesa Veterinary Hospital, Mesa, AZ, USA
J Vet Intern Med 17:622-31. 2003..By comparison, dogs in which predisposing disorders were corrected or those that were treated with low-dose, long-term antibiotic regimens subjectively had better control...
